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The map label for this gene is surA [H]

Identifier: 126207884

GI number: 126207884

Start: 454398

End: 455348

Strand: Reverse

Name: surA [H]

Synonym: APL_0400

Alternate gene names: 126207884

Gene position: 455348-454398 (Counterclockwise)

Preceding gene: 126207885

Following gene: 126207883

Centisome position: 20.02

GC content: 41.22

Gene sequence:

>951_bases
ATGAAATTAATCTCTGCAAAATCATTATTAGTCGCATTGGTTACTGCAATCGGCATTTCTCAAACGGCAATTGCCATTGA
AGAACGTGTCGTAGCACTTGTCGATGGCGTACCGGTAATGGAAAGCCAAGTTCAGCGCGCTTTAGGTAAAAAAGCAAATT
CCGAAGCAAATCACAAAGCCGCGTTAGAACAAATTATTGATGATCTTTTAGTACAAAAAGCGGTCAAAGAAGCGGGCGTA
AAAGTCAATTACTCTAAAGTGGATCAAGTGATTGAAGATATCGCGGCACGTAACGGTATCACTTACGGTCAGCTACTCGA
TGCGTTGGATTATCAAGGTATTACCTTAGAGCAATACCGTCAGCAAATCGCACAACAAATGGCGATGGAACAAGTACGTC
ATATCAGTATCGGTAAATCAATTCAAGTTGATCCGAAAGACGTTCACGCTTATGCAAAAGAATTACTCGAAAAAGATAAA
GCAAACGGCAAATTGAAAAATGTGACCGGCGTTCAACATCGAGTCAGTCATATTTTAATTAAAACGACACCGGTGTTAAA
TGATATTCAGGCAAAAGCGAAATTAGCTCAAATTGTTGCGGATATTAAAGCGGGTAAAACCACTTTTGAAGAAGCGGCGA
AAGCGAATTCGGTCGATTATCTTTCGGCTGCGGACGGTGGTGATTTAGGTTATAATTTCTTAGATATTTATGATCCTGCA
TTTGCAAAAGCCGCAAGCACGGCAAAACAAGAGCAAATTACCGCACCGTTTAAATCCCAATTCGGTTGGCATATTCTTAA
GGTAACCGGTACACAACAAGGCGACCGTACAGAAGACGCTTATAACCAACGTGCTTACGAGCAATTAGTGGACAAACAAG
CGCAAGAAGCGGCAAAAGACTGGGTAAAAGCATTGAGAAAAACCGCTGACGTTCAGTACGTTGGTAAATAA

Upstream 100 bases:

>100_bases
TTCGAGCGAAAGACGAGTGAATAAATACTAGGAACCTTTTTTAGAAAAATAGCTCTAATTATATCGGGGCTTATCTTTAA
CCTTTAGTAGGAAATAATAA

Downstream 100 bases:

>100_bases
ACATAACGATTTATCTGAGAACCTCGCTATTTGCGGGGTTCTTTGCTTATTTTAAAAGGATAACAATGAGTAATCAAAAT
TCAAAAAAACATTTAGGTCA

Product: peptidyl-prolyl cis-trans isomerase SurA

Products: Isomerized Proline [C]

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKLISAKSLLVALVTAIGISQTAIAIEERVVALVDGVPVMESQVQRALGKKANSEANHKAALEQIIDDLLVQKAVKEAGV
KVNYSKVDQVIEDIAARNGITYGQLLDALDYQGITLEQYRQQIAQQMAMEQVRHISIGKSIQVDPKDVHAYAKELLEKDK
ANGKLKNVTGVQHRVSHILIKTTPVLNDIQAKAKLAQIVADIKAGKTTFEEAAKANSVDYLSAADGGDLGYNFLDIYDPA
FAKAASTAKQEQITAPFKSQFGWHILKVTGTQQGDRTEDAYNQRAYEQLVDKQAQEAAKDWVKALRKTADVQYVGK

Sequences:

>Translated_316_residues
MKLISAKSLLVALVTAIGISQTAIAIEERVVALVDGVPVMESQVQRALGKKANSEANHKAALEQIIDDLLVQKAVKEAGV
KVNYSKVDQVIEDIAARNGITYGQLLDALDYQGITLEQYRQQIAQQMAMEQVRHISIGKSIQVDPKDVHAYAKELLEKDK
ANGKLKNVTGVQHRVSHILIKTTPVLNDIQAKAKLAQIVADIKAGKTTFEEAAKANSVDYLSAADGGDLGYNFLDIYDPA
FAKAASTAKQEQITAPFKSQFGWHILKVTGTQQGDRTEDAYNQRAYEQLVDKQAQEAAKDWVKALRKTADVQYVGK
>Mature_316_residues
MKLISAKSLLVALVTAIGISQTAIAIEERVVALVDGVPVMESQVQRALGKKANSEANHKAALEQIIDDLLVQKAVKEAGV
KVNYSKVDQVIEDIAARNGITYGQLLDALDYQGITLEQYRQQIAQQMAMEQVRHISIGKSIQVDPKDVHAYAKELLEKDK
ANGKLKNVTGVQHRVSHILIKTTPVLNDIQAKAKLAQIVADIKAGKTTFEEAAKANSVDYLSAADGGDLGYNFLDIYDPA
FAKAASTAKQEQITAPFKSQFGWHILKVTGTQQGDRTEDAYNQRAYEQLVDKQAQEAAKDWVKALRKTADVQYVGK

Specific function: Chaperone involved in the folding of extracytoplasmic proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=160, Percent_Identity=41.25, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: 5.2.1.8 [C]

Molecular weight: Translated: 34600; Mature: 34600

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLISAKSLLVALVTAIGISQTAIAIEERVVALVDGVPVMESQVQRALGKKANSEANHKA
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHH
ALEQIIDDLLVQKAVKEAGVKVNYSKVDQVIEDIAARNGITYGQLLDALDYQGITLEQYR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHH
QQIAQQMAMEQVRHISIGKSIQVDPKDVHAYAKELLEKDKANGKLKNVTGVQHRVSHILI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
KTTPVLNDIQAKAKLAQIVADIKAGKTTFEEAAKANSVDYLSAADGGDLGYNFLDIYDPA
HCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCCCCCHHHHHCCHH
FAKAASTAKQEQITAPFKSQFGWHILKVTGTQQGDRTEDAYNQRAYEQLVDKQAQEAAKD
HHHHHHHHHHHHHCCCHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WVKALRKTADVQYVGK
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKLISAKSLLVALVTAIGISQTAIAIEERVVALVDGVPVMESQVQRALGKKANSEANHKA
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHH
ALEQIIDDLLVQKAVKEAGVKVNYSKVDQVIEDIAARNGITYGQLLDALDYQGITLEQYR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHH
QQIAQQMAMEQVRHISIGKSIQVDPKDVHAYAKELLEKDKANGKLKNVTGVQHRVSHILI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
KTTPVLNDIQAKAKLAQIVADIKAGKTTFEEAAKANSVDYLSAADGGDLGYNFLDIYDPA
HCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCCCCCHHHHHCCHH
FAKAASTAKQEQITAPFKSQFGWHILKVTGTQQGDRTEDAYNQRAYEQLVDKQAQEAAKD
HHHHHHHHHHHHHCCCHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WVKALRKTADVQYVGK
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proline Imidic Peptide Bonds In Oligopeptides [C]

Specific reaction: Cis-Trans Isomerization Of Proline Imidic Peptide Bonds In Oligopeptides. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]