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The map label for this gene is oxaA

Identifier: 126176561

GI number: 126176561

Start: 5124611

End: 5126236

Strand: Reverse

Name: oxaA

Synonym: Sbal_4380

Alternate gene names: 126176561

Gene position: 5126236-5124611 (Counterclockwise)

Preceding gene: 126176562

Following gene: 126176560

Centisome position: 99.98

GC content: 45.14

Gene sequence:

>1626_bases
ATGGAATCTCAACGCAATATATTGCTCATAGGACTACTGTTTGTCAGCTTTTTGCTGTGGCAACAGTGGCAAGCAGACAA
AGCTCCTAAACCAGTTGCAACCGAATCGTCCTTAGTGGCGAACGCGGCAAACTCACACAGTGCCGATGTTCCAGAAGCTG
ATACAGGTGTTCCTGCAGCAGTGACAGCAACCAGCAAACTGATTACCGTGAAAACCGACCAGTTGGATGTTCAAATTAAT
CCAATCGGTGGCGACATTGTTTTTGCTGCGTTAGTTTCACACAAGATGGAACAGGATAAAGATCAACCCTTCGTGTTGCT
TGAGCAAACGAAAGATTTCACTTATATAGCCCAGAGCGGTCTTATAGGTCGCGATGGTATCGACAGTAGCGCCAAAGGCC
GTGCCGCATTTAGCACTGCAGCGACTGAATATACCTTAGCCGAAGGTCAAGACACTTTAGAAGTGCCGTTAACTTATGTA
GCCGACAATGGCGTGACATACACTAAAGTGTTTGTATTCCATCGCGGTAAGTTCAACGTCGATGTTGACTATAAAATCAA
CAACACTTCAGCGGCTCCGCTGCAAGTTCAGATGTACGGTCAAATTAAACAAACGATTAAACCGTCTGAAAGCAGCATGG
TTATGCCTACCTACCGTGGTGGCGCATTCTCTACGCAAGATGTGCGTTATGAGAAATACAAATTTGATGACATGGCGAAA
AGCAACCTGAACCAAGCGACGTTGGGCGGTTGGGCTGCCATGCTACAACATTACTTTGTTTCAGCTTGGATCCCACCGGC
TACCGACAGCAACACAATTTTCTCTAGTGTCAGTGCGGGCGGTTTAGCCAATATTGGTTTCCGCGGCGCGGTATATGATA
TTGCACCAGGTGCGACTCAAGAAATTAGCTCACAGTTCTACGTTGGTCCTAAGGATCAAAAAGCACTGTCAGCCATCTCT
GATACCTTAAACCTAGTGGTCGATTACGGCTTCCTATGGTGGTTAGCTGTACCTATTCACTGGCTATTGATGTTCTATCA
ATCATTCGTCGGTAACTGGGGTATGGCTATTATTCTGATCACCCTAACCGTTCGTGGTTTACTGTTCCCACTGACAAAAG
CGCAGTACACCTCAATGGCGAAGATGCGTAACCTGCAACCTAAACTGACTGACTTGAAAGAACGCTTTGGTGATGACCGT
CAAAAGATGGGTCAGGCCATGATGGAGCTGTATAAGAAAGAAAAAGTTAACCCTATGGGTGGCTGTTTACCTATTATTTT
ACAGATGCCAATCTTCATTGCCTTGTACTGGGTATTGTTAGAAAGCTTCGAATTACGTCACGCACCATTTATGCTGTGGA
TCCACGATTTATCGGTACAAGATCCTTACTACATATTGCCGTTGCTGATGGGCGTATCTATGTTTGTGATGCAGAAGATG
CAACCTATTGCACCGACTATGGACCCAATGCAAGTGAAAATGATGCAATGGATGCCAGTGATCTTTACTGTATTCTTCCT
CTGGTTCCCAGCGGGTCTAGTACTGTACTGGTTAGTAGGTAACATAGTTGCTATCACGCAACAGAAGATTATTTATGCAG
GTCTGGCGAAAAAAGGCTTAAAATAA

Upstream 100 bases:

>100_bases
TTGTTGGTTTGCATTGAAACGCATATTAAAATGTCACCCTTTACATCCCGGCGGTAGTGATCCCGTCCCCCCTAAAAATG
ACAGGTGTAATAAATAGGCT

Downstream 100 bases:

>100_bases
GCCTAAGATTTGCAAGACTCTAGCGCATCGTTACAGATTAATGTGAACGAATGACACTAAAAGGCGGCTTAATTGGCCGC
CTTTTCCTTTACATATTTTA

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANAANSHSADVPEADTGVPAAVTATSKLITVKTDQLDVQIN
PIGGDIVFAALVSHKMEQDKDQPFVLLEQTKDFTYIAQSGLIGRDGIDSSAKGRAAFSTAATEYTLAEGQDTLEVPLTYV
ADNGVTYTKVFVFHRGKFNVDVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMVMPTYRGGAFSTQDVRYEKYKFDDMAK
SNLNQATLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQEISSQFYVGPKDQKALSAIS
DTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGMAIILITLTVRGLLFPLTKAQYTSMAKMRNLQPKLTDLKERFGDDR
QKMGQAMMELYKKEKVNPMGGCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFVMQKM
QPIAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNIVAITQQKIIYAGLAKKGLK

Sequences:

>Translated_541_residues
MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANAANSHSADVPEADTGVPAAVTATSKLITVKTDQLDVQIN
PIGGDIVFAALVSHKMEQDKDQPFVLLEQTKDFTYIAQSGLIGRDGIDSSAKGRAAFSTAATEYTLAEGQDTLEVPLTYV
ADNGVTYTKVFVFHRGKFNVDVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMVMPTYRGGAFSTQDVRYEKYKFDDMAK
SNLNQATLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQEISSQFYVGPKDQKALSAIS
DTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGMAIILITLTVRGLLFPLTKAQYTSMAKMRNLQPKLTDLKERFGDDR
QKMGQAMMELYKKEKVNPMGGCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFVMQKM
QPIAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNIVAITQQKIIYAGLAKKGLK
>Mature_541_residues
MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANAANSHSADVPEADTGVPAAVTATSKLITVKTDQLDVQIN
PIGGDIVFAALVSHKMEQDKDQPFVLLEQTKDFTYIAQSGLIGRDGIDSSAKGRAAFSTAATEYTLAEGQDTLEVPLTYV
ADNGVTYTKVFVFHRGKFNVDVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMVMPTYRGGAFSTQDVRYEKYKFDDMAK
SNLNQATLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQEISSQFYVGPKDQKALSAIS
DTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGMAIILITLTVRGLLFPLTKAQYTSMAKMRNLQPKLTDLKERFGDDR
QKMGQAMMELYKKEKVNPMGGCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFVMQKM
QPIAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNIVAITQQKIIYAGLAKKGLK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=548, Percent_Identity=52.007299270073, Blast_Score=566, Evalue=1e-162,
Organism=Drosophila melanogaster, GI24662345, Length=198, Percent_Identity=25.2525252525253, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356443, Length=198, Percent_Identity=25.2525252525253, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_SHEB2 (B8EDW5)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002360214.1
- ProteinModelPortal:   B8EDW5
- SMR:   B8EDW5
- GeneID:   7089130
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_4325
- HOGENOM:   HBG507812
- OMA:   TYRGAAF
- ProtClustDB:   CLSK905534
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 60380; Mature: 60380

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x189e661c)-; HASH(0x1a15eb44)-; HASH(0x195c47c4)-; HASH(0x40a9a878)-; HASH(0x1a6e9c48)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANAANSHSADVPEADTGVPAA
CCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEE
VTATSKLITVKTDQLDVQINPIGGDIVFAALVSHKMEQDKDQPFVLLEQTKDFTYIAQSG
EECCCEEEEEEECEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEHHHCC
LIGRDGIDSSAKGRAAFSTAATEYTLAEGQDTLEVPLTYVADNGVTYTKVFVFHRGKFNV
CCCCCCCCCCCCCCCHHHHHHCEEEECCCCCCEECCEEEEECCCCEEEEEEEEECCEEEE
DVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMVMPTYRGGAFSTQDVRYEKYKFDDMAK
EEEEEECCCCCCCEEEEEHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHCCHHHHH
SNLNQATLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEECCCCCHH
EISSQFYVGPKDQKALSAISDTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGMAIILI
HHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
TLTVRGLLFPLTKAQYTSMAKMRNLQPKLTDLKERFGDDRQKMGQAMMELYKKEKVNPMG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
GCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFVMQKM
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QPIAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNIVAITQQKIIYAGLAKKGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
K
H
>Mature Secondary Structure
MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANAANSHSADVPEADTGVPAA
CCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEE
VTATSKLITVKTDQLDVQINPIGGDIVFAALVSHKMEQDKDQPFVLLEQTKDFTYIAQSG
EECCCEEEEEEECEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEHHHCC
LIGRDGIDSSAKGRAAFSTAATEYTLAEGQDTLEVPLTYVADNGVTYTKVFVFHRGKFNV
CCCCCCCCCCCCCCCHHHHHHCEEEECCCCCCEECCEEEEECCCCEEEEEEEEECCEEEE
DVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMVMPTYRGGAFSTQDVRYEKYKFDDMAK
EEEEEECCCCCCCEEEEEHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHCCHHHHH
SNLNQATLGGWAAMLQHYFVSAWIPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGATQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEECCCCCHH
EISSQFYVGPKDQKALSAISDTLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGMAIILI
HHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
TLTVRGLLFPLTKAQYTSMAKMRNLQPKLTDLKERFGDDRQKMGQAMMELYKKEKVNPMG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
GCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFVMQKM
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QPIAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNIVAITQQKIIYAGLAKKGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
K
H

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA