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The map label for this gene is glmU [H]

Identifier: 126176545

GI number: 126176545

Start: 5108866

End: 5110248

Strand: Reverse

Name: glmU [H]

Synonym: Sbal_4364

Alternate gene names: 126176545

Gene position: 5110248-5108866 (Counterclockwise)

Preceding gene: 126176546

Following gene: 126176544

Centisome position: 99.67

GC content: 47.94

Gene sequence:

>1383_bases
ATGGCATTAAATGTAGTGATCTTAGCGGCTGGCAAGGGAACACGGATGCGTTCTGATCTTCCTAAGGTATTACATCCCAT
CGCCCATAAGAGCATGGTGCAACATGTCATCGATACCGCTCATAAAGTGGGCAGCGATGCGATTCAGTTAGTCTACGGTT
ATGGTGCTGACAAGCTACAAGCCAGCTTAGGTGAGCAACAACTTAACTGGGTATTGCAAGCTGAGCAATTAGGCACGGGA
CATGCGGTTGCGCAAGCGAGCCCGCATATTGCCGATAGCGATACAGTGCTTATTCTTTACGGCGATGTGCCGCTTATCCA
ACAATCAACTCTGGAAGCCTTACTCGCTGCCCGTCCTGAAAATGGCGTGGCCATCTTAACGGTGAATTTAGGTAATCCTA
TGGGTTATGGCCGTATCGTTCGTACTCCATGTGAAGGTCAAGAACAAGGTAAAGTAGTCGGTATTATTGAGCAGAAAGAT
GCTACAGCAGAGCAGCTACTGATCAACGAAATCAATACCGGCATCATGGCCGTTCCAGGTAAACAACTTAAAGCTTGGTT
GAGCCGTTTATCCAACAACAATGCCCAAGGCGAATATTATCTAACGGATATTATTGCCATGGCGCACGCTGATGGTGTTG
CTATTGATACTGCCCAACCACAATCTGCGATTGAAGTGGAAGGCGCTAATAACCGCGTGCAACTGGCGCAACTTGAACGC
GCTTACCAAGCCCGTGAAGCCGAAAAACTGATGTTGGCGGGAGCGAACCTGCGCGACCCAAGCCGTATCGATATCCGTGG
TGACGTCACCGTCGGTATGGATGTGATGATCGATATCAACGTGATATTCGAAGGCAAAGTGACCTTAGGTAATAATGTCA
CTATTGGCGCTGGCGCGATTTTAATCGATTGTGAGATTGCCGATAACGCTGAGATCAAACCTTACTCTATTATCGAAGGC
GCTAAGCTTGGTGTTGCTGCCAGTGCTGGTCCATTTGCGCGCTTACGTCCCGGCGCAGAGCTTAAGCAAGATGCGCACAT
TGGTAACTTTGTTGAAGTGAAGAAAGCGGTTATCGGCGTGGGTTCTAAGGCTGGACACTTAGCCTATTTAGGTGATGCTA
TTATAGGTGATGGCGTTAATATCGGCGCTGGCACTATTACTTGTAATTATGATGGCGCGAATAAGCATCTTACCGTTATA
GAAGATAATGTCTTTGTTGGCTCAGACACTCAGCTGGTGGCACCTGTCACTATCGGTAAAGGCGCAACCTTAGGCGCTGG
CTCAACCATTACCCGCGATGTGGGTGAGAATGAGTTAGTCATTACCCGTGTTAAACAAAAGCACCTGACGGGTTGGCAAC
GTCCAGTCAAAATTAAAAAGTAA

Upstream 100 bases:

>100_bases
ACTATCCGCTTCGCTTTTCGATGTGCTTTCCGTTAAAATTGCGCAACAAAATCGACCGTAATTTTTTCACCCTCTTGGGT
ATTTGTTCAAGGATATGGCA

Downstream 100 bases:

>100_bases
GTTTATTTAACTCAACTGAGTATCTATAAAGCGGCCATGTGCCGCTTTTATATTTAGTCAGATTGTTGGAAATTCGATTC
GTTTAATTCAGATGGAAAAC

Product: UDP-N-acetylglucosamine pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHKVGSDAIQLVYGYGADKLQASLGEQQLNWVLQAEQLGTG
HAVAQASPHIADSDTVLILYGDVPLIQQSTLEALLAARPENGVAILTVNLGNPMGYGRIVRTPCEGQEQGKVVGIIEQKD
ATAEQLLINEINTGIMAVPGKQLKAWLSRLSNNNAQGEYYLTDIIAMAHADGVAIDTAQPQSAIEVEGANNRVQLAQLER
AYQAREAEKLMLAGANLRDPSRIDIRGDVTVGMDVMIDINVIFEGKVTLGNNVTIGAGAILIDCEIADNAEIKPYSIIEG
AKLGVAASAGPFARLRPGAELKQDAHIGNFVEVKKAVIGVGSKAGHLAYLGDAIIGDGVNIGAGTITCNYDGANKHLTVI
EDNVFVGSDTQLVAPVTIGKGATLGAGSTITRDVGENELVITRVKQKHLTGWQRPVKIKK

Sequences:

>Translated_460_residues
MALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHKVGSDAIQLVYGYGADKLQASLGEQQLNWVLQAEQLGTG
HAVAQASPHIADSDTVLILYGDVPLIQQSTLEALLAARPENGVAILTVNLGNPMGYGRIVRTPCEGQEQGKVVGIIEQKD
ATAEQLLINEINTGIMAVPGKQLKAWLSRLSNNNAQGEYYLTDIIAMAHADGVAIDTAQPQSAIEVEGANNRVQLAQLER
AYQAREAEKLMLAGANLRDPSRIDIRGDVTVGMDVMIDINVIFEGKVTLGNNVTIGAGAILIDCEIADNAEIKPYSIIEG
AKLGVAASAGPFARLRPGAELKQDAHIGNFVEVKKAVIGVGSKAGHLAYLGDAIIGDGVNIGAGTITCNYDGANKHLTVI
EDNVFVGSDTQLVAPVTIGKGATLGAGSTITRDVGENELVITRVKQKHLTGWQRPVKIKK
>Mature_459_residues
ALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHKVGSDAIQLVYGYGADKLQASLGEQQLNWVLQAEQLGTGH
AVAQASPHIADSDTVLILYGDVPLIQQSTLEALLAARPENGVAILTVNLGNPMGYGRIVRTPCEGQEQGKVVGIIEQKDA
TAEQLLINEINTGIMAVPGKQLKAWLSRLSNNNAQGEYYLTDIIAMAHADGVAIDTAQPQSAIEVEGANNRVQLAQLERA
YQAREAEKLMLAGANLRDPSRIDIRGDVTVGMDVMIDINVIFEGKVTLGNNVTIGAGAILIDCEIADNAEIKPYSIIEGA
KLGVAASAGPFARLRPGAELKQDAHIGNFVEVKKAVIGVGSKAGHLAYLGDAIIGDGVNIGAGTITCNYDGANKHLTVIE
DNVFVGSDTQLVAPVTIGKGATLGAGSTITRDVGENELVITRVKQKHLTGWQRPVKIKK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=458, Percent_Identity=62.4454148471616, Blast_Score=582, Evalue=1e-167,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 48656; Mature: 48525

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHKVGSDAIQLVYGYGADKLQ
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHH
ASLGEQQLNWVLQAEQLGTGHAVAQASPHIADSDTVLILYGDVPLIQQSTLEALLAARPE
HHHCHHHHHEEEEHHHCCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCC
NGVAILTVNLGNPMGYGRIVRTPCEGQEQGKVVGIIEQKDATAEQLLINEINTGIMAVPG
CCEEEEEEECCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECC
KQLKAWLSRLSNNNAQGEYYLTDIIAMAHADGVAIDTAQPQSAIEVEGANNRVQLAQLER
HHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCCEEEECCCCCCEEEEECCCCEEEHHHHHH
AYQAREAEKLMLAGANLRDPSRIDIRGDVTVGMDVMIDINVIFEGKVTLGNNVTIGAGAI
HHHHHHHHEEEEECCCCCCCCEEEEEECEEECEEEEEEEEEEEEEEEEECCEEEEECCEE
LIDCEIADNAEIKPYSIIEGAKLGVAASAGPFARLRPGAELKQDAHIGNFVEVKKAVIGV
EEEEEECCCCCCCCEEEECCCCCCEEECCCCHHHCCCCCCHHCCCCCCCHHHHHHHHHCC
GSKAGHLAYLGDAIIGDGVNIGAGTITCNYDGANKHLTVIEDNVFVGSDTQLVAPVTIGK
CCCCCCEEEECCEEECCCCEECCEEEEEEECCCCCEEEEEECCEEECCCCEEEEEEEECC
GATLGAGSTITRDVGENELVITRVKQKHLTGWQRPVKIKK
CCCCCCCCCEECCCCCCCEEEEEEHHHHCCCCCCCEEECC
>Mature Secondary Structure 
ALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHKVGSDAIQLVYGYGADKLQ
CEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHH
ASLGEQQLNWVLQAEQLGTGHAVAQASPHIADSDTVLILYGDVPLIQQSTLEALLAARPE
HHHCHHHHHEEEEHHHCCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCC
NGVAILTVNLGNPMGYGRIVRTPCEGQEQGKVVGIIEQKDATAEQLLINEINTGIMAVPG
CCEEEEEEECCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECC
KQLKAWLSRLSNNNAQGEYYLTDIIAMAHADGVAIDTAQPQSAIEVEGANNRVQLAQLER
HHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCCEEEECCCCCCEEEEECCCCEEEHHHHHH
AYQAREAEKLMLAGANLRDPSRIDIRGDVTVGMDVMIDINVIFEGKVTLGNNVTIGAGAI
HHHHHHHHEEEEECCCCCCCCEEEEEECEEECEEEEEEEEEEEEEEEEECCEEEEECCEE
LIDCEIADNAEIKPYSIIEGAKLGVAASAGPFARLRPGAELKQDAHIGNFVEVKKAVIGV
EEEEEECCCCCCCCEEEECCCCCCEEECCCCHHHCCCCCCHHCCCCCCCHHHHHHHHHCC
GSKAGHLAYLGDAIIGDGVNIGAGTITCNYDGANKHLTVIEDNVFVGSDTQLVAPVTIGK
CCCCCCEEEECCEEECCCCEECCEEEEEEECCCCCEEEEEECCEEECCCCEEEEEEEECC
GATLGAGSTITRDVGENELVITRVKQKHLTGWQRPVKIKK
CCCCCCCCCEECCCCCCCEEEEEEHHHHCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA