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The map label for this gene is gntU [H]

Identifier: 126176274

GI number: 126176274

Start: 4796461

End: 4797804

Strand: Direct

Name: gntU [H]

Synonym: Sbal_4088

Alternate gene names: 126176274

Gene position: 4796461-4797804 (Clockwise)

Preceding gene: 126176272

Following gene: 126176278

Centisome position: 93.55

GC content: 49.78

Gene sequence:

>1344_bases
ATGTCTGATATGTCATTGATTCTGACAGCGCTGGGTTCAATCGCCCTGCTACTGTTCTTAGTGATGAAAGTGAGATTACA
TGCAGTGGTATCACTGATACTGGTGTCGATCATTGCCGGTCTTTTCTCTGGCATGAACCCAGCCGATATCACTAATACTA
TTCAACAAGGTATGGGGGGTACACTGGGCTTTGTGGCGGTGGTGGTCGCTTTGGGAGCGATGTTTGGTCGCGTCATGGAA
GAGACTGGTGCGCTAGATCAGATAGCCCATACACTGCTGAATAAATTTGGTAACGACAAAGCCCACTGGGCGATGACCTT
TACTGGCTTTATCTGTGCGCTACCCCTCTTCTTCGACGTTGCTGTGGTGTTGCTGATTGGCATCGCCTTTGCCGTGGTTC
GTAAAGGGGGCGGTAGCGTCGTTAAAATTGGTATTTCGCTGCTCGCGGGTATTGCCACCTGTCAGGCGTTTCTTATCCCT
GCACCTGGGCCTATTTTGGTCGCTTCACAGCTCAATGCCGACTTTGGCTACATGATAGTCTTCGGTCTGCTGGCATCGAT
TCCGGCGATGATTCTAGGCGGTCCACTCTTTGCCAGTCTCATCTCACAAAAAGTCCATGTTGAGCTGCCATCTCACGAGC
AGCAAGAAAAAGGTGAACGAGAAGGCGGACCTATCCCCTCATTCGCGCTCTCAATCAGTATTGTGATTTTTCCACTGCTG
CTTATCGGTTTGAAGACGGTTGTGTCGCGCTTTATTGATGAAAAATCCGATCTGCATAATTGGCTCGCCTTGATAGGTCA
TCCTTTCACCGCCATTCTGCTAGCCTGTTTAATCGCATTTTATGTGCTGGGCGTGAGACGTAACATTCCCAATGACCGCA
TCATGGAAATCTGTAGCAGTGCGCTCCAACCTGCGGGGGTTATTATTCTCGTCACCGGTGCTGGCGGCGTGTTCAAGCAA
GTGCTGATTGATTCGGGTGTCGGCGATGCTTTAGGGAATATGTTGGCAGGTTCTGGATTACCGATTGTGATACTGGCATT
TATTTTGTCGGCTTCGGTGCGCGTTATCCAAGGTTCGGCAACCGTGGCCATGTTAACGGCTTGCGGCCTTATCATCCCGA
TACTTGAACCATTGAACTTAGATGGTGCTCAATTGGCGGCGATTACGATTGCCATTGGCGGTGGTTCGATTGTGCTCTCG
CACGTTAATGACTCAGGCTTCTGGCTCGCAAACCGTTTTCTTGGATTGTCAGAAAAACAAACGCTGCAAACGTGGACGGT
AATGGAAACCATTATTGGCACGACGGGCGGCATAGTTGCAGTCATCATCTCAGCGTTTCTCTAA

Upstream 100 bases:

>100_bases
CTCGAATTTAGTCACTTCCCACTCTATCATATTACGGGTAACATGTTACCGGTAACCTACAAAAATGTGGACAACTTAAC
TAACAAGGAAAAGTCCTCTT

Downstream 100 bases:

>100_bases
CGCTAGCCAGAGATCAAAAACCTTAGGCATTAGCCGTTAAGCGAAAGATCGAGGGGAAGTCTACAATGTTTCCCCTAGAT
CAATACGATAGCCCAGATCG

Product: low affinity gluconate transporter

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: Gluconate permease; Gnt-I system [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSDMSLILTALGSIALLLFLVMKVRLHAVVSLILVSIIAGLFSGMNPADITNTIQQGMGGTLGFVAVVVALGAMFGRVME
ETGALDQIAHTLLNKFGNDKAHWAMTFTGFICALPLFFDVAVVLLIGIAFAVVRKGGGSVVKIGISLLAGIATCQAFLIP
APGPILVASQLNADFGYMIVFGLLASIPAMILGGPLFASLISQKVHVELPSHEQQEKGEREGGPIPSFALSISIVIFPLL
LIGLKTVVSRFIDEKSDLHNWLALIGHPFTAILLACLIAFYVLGVRRNIPNDRIMEICSSALQPAGVIILVTGAGGVFKQ
VLIDSGVGDALGNMLAGSGLPIVILAFILSASVRVIQGSATVAMLTACGLIIPILEPLNLDGAQLAAITIAIGGGSIVLS
HVNDSGFWLANRFLGLSEKQTLQTWTVMETIIGTTGGIVAVIISAFL

Sequences:

>Translated_447_residues
MSDMSLILTALGSIALLLFLVMKVRLHAVVSLILVSIIAGLFSGMNPADITNTIQQGMGGTLGFVAVVVALGAMFGRVME
ETGALDQIAHTLLNKFGNDKAHWAMTFTGFICALPLFFDVAVVLLIGIAFAVVRKGGGSVVKIGISLLAGIATCQAFLIP
APGPILVASQLNADFGYMIVFGLLASIPAMILGGPLFASLISQKVHVELPSHEQQEKGEREGGPIPSFALSISIVIFPLL
LIGLKTVVSRFIDEKSDLHNWLALIGHPFTAILLACLIAFYVLGVRRNIPNDRIMEICSSALQPAGVIILVTGAGGVFKQ
VLIDSGVGDALGNMLAGSGLPIVILAFILSASVRVIQGSATVAMLTACGLIIPILEPLNLDGAQLAAITIAIGGGSIVLS
HVNDSGFWLANRFLGLSEKQTLQTWTVMETIIGTTGGIVAVIISAFL
>Mature_446_residues
SDMSLILTALGSIALLLFLVMKVRLHAVVSLILVSIIAGLFSGMNPADITNTIQQGMGGTLGFVAVVVALGAMFGRVMEE
TGALDQIAHTLLNKFGNDKAHWAMTFTGFICALPLFFDVAVVLLIGIAFAVVRKGGGSVVKIGISLLAGIATCQAFLIPA
PGPILVASQLNADFGYMIVFGLLASIPAMILGGPLFASLISQKVHVELPSHEQQEKGEREGGPIPSFALSISIVIFPLLL
IGLKTVVSRFIDEKSDLHNWLALIGHPFTAILLACLIAFYVLGVRRNIPNDRIMEICSSALQPAGVIILVTGAGGVFKQV
LIDSGVGDALGNMLAGSGLPIVILAFILSASVRVIQGSATVAMLTACGLIIPILEPLNLDGAQLAAITIAIGGGSIVLSH
VNDSGFWLANRFLGLSEKQTLQTWTVMETIIGTTGGIVAVIISAFL

Specific function: Part of the gluconate utilization system Gnt-I; low- affinity intake of gluconate [H]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994939, Length=443, Percent_Identity=57.7878103837472, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI1790716, Length=449, Percent_Identity=33.8530066815145, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1789097, Length=447, Percent_Identity=36.9127516778523, Blast_Score=251, Evalue=9e-68,
Organism=Escherichia coli, GI48994935, Length=435, Percent_Identity=32.183908045977, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI2367370, Length=424, Percent_Identity=33.4905660377358, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI1788707, Length=430, Percent_Identity=33.0232558139535, Blast_Score=234, Evalue=6e-63,
Organism=Escherichia coli, GI1790776, Length=441, Percent_Identity=29.7052154195011, Blast_Score=216, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 46640; Mature: 46509

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDMSLILTALGSIALLLFLVMKVRLHAVVSLILVSIIAGLFSGMNPADITNTIQQGMGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
TLGFVAVVVALGAMFGRVMEETGALDQIAHTLLNKFGNDKAHWAMTFTGFICALPLFFDV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AVVLLIGIAFAVVRKGGGSVVKIGISLLAGIATCQAFLIPAPGPILVASQLNADFGYMIV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCHHHHHH
FGLLASIPAMILGGPLFASLISQKVHVELPSHEQQEKGEREGGPIPSFALSISIVIFPLL
HHHHHHHHHHHHCHHHHHHHHCCHHEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LIGLKTVVSRFIDEKSDLHNWLALIGHPFTAILLACLIAFYVLGVRRNIPNDRIMEICSS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ALQPAGVIILVTGAGGVFKQVLIDSGVGDALGNMLAGSGLPIVILAFILSASVRVIQGSA
HCCCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHCCHHEEECCH
TVAMLTACGLIIPILEPLNLDGAQLAAITIAIGGGSIVLSHVNDSGFWLANRFLGLSEKQ
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCEEEEEEECCCCHHHHHHHCCCCCHH
TLQTWTVMETIIGTTGGIVAVIISAFL
HHHHHHHHHHHHCCCCHHHHHHHHHHC
>Mature Secondary Structure 
SDMSLILTALGSIALLLFLVMKVRLHAVVSLILVSIIAGLFSGMNPADITNTIQQGMGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
TLGFVAVVVALGAMFGRVMEETGALDQIAHTLLNKFGNDKAHWAMTFTGFICALPLFFDV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AVVLLIGIAFAVVRKGGGSVVKIGISLLAGIATCQAFLIPAPGPILVASQLNADFGYMIV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCHHHHHH
FGLLASIPAMILGGPLFASLISQKVHVELPSHEQQEKGEREGGPIPSFALSISIVIFPLL
HHHHHHHHHHHHCHHHHHHHHCCHHEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LIGLKTVVSRFIDEKSDLHNWLALIGHPFTAILLACLIAFYVLGVRRNIPNDRIMEICSS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ALQPAGVIILVTGAGGVFKQVLIDSGVGDALGNMLAGSGLPIVILAFILSASVRVIQGSA
HCCCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHCCHHEEECCH
TVAMLTACGLIIPILEPLNLDGAQLAAITIAIGGGSIVLSHVNDSGFWLANRFLGLSEKQ
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCEEEEEEECCCCHHHHHHHCCCCCHH
TLQTWTVMETIIGTTGGIVAVIISAFL
HHHHHHHHHHHHCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]