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The map label for this gene is actR [H]

Identifier: 126176066

GI number: 126176066

Start: 4552712

End: 4553263

Strand: Reverse

Name: actR [H]

Synonym: Sbal_3876

Alternate gene names: 126176066

Gene position: 4553263-4552712 (Counterclockwise)

Preceding gene: 126176067

Following gene: 126176062

Centisome position: 88.8

GC content: 52.72

Gene sequence:

>552_bases
ATGAAACGTTTATTGATTGTCGAGGATGATCTTTCTCTGGCGAGTATTTTAGGCCGACGGCTCACGCGCCACGGCTTTGA
GTGCCGCTTAACCCATGATGCCAGCGATGCTCTGCTGGTGGCGCGGGAGTTTCGCCCTAGCCACATTTTGTTGGACATGA
AGCTGGCCGAAGCTAACGGCCTAGGGCTAATTGTGCCTCTACGTAACCTGCTGCCTAAGGTGACCATGGTGTTGCTCACC
GGTTATGCCAGTATCGCCACTGCGGTGGAAGCGATTCGCCTCGGCGCCGATAATTATTTAGCTAAACCTGTGGATACTCA
AACCTTGCTCGCCGCGTTGGAAATGGAAGGGCATTCCCATACCCTTCAAGAGGATGAAGTCGATGACTCGCCCCTTAATC
CTAAGCGTTTGGAGTGGGAACACATTCAGCAAGTACTTAATGCCAACCAAGGCAATGTGTCCGCCACCGCCCGCCAACTC
GGAATGCATCGCCGCACCTTACAACGTAAGTTGCTCAAGAAGCCTGTGGGTGAAAGTGGCCATTTGAAGTAA

Upstream 100 bases:

>100_bases
ATCCCCAAGGCGGTACTGTGGCACAAATTCGCTTTACGATTCTAAAGGACAAAGCGGCATCGTTATCGCCCAAGACTAAG
GCCGCTGACGGAGTCAGATC

Downstream 100 bases:

>100_bases
CCAAGGCAATGTGTCCGCTACCGCCCGACAATTGGGGATGCATCTTCGCACCTTACAACGTAAGTTACTCAAAAAACCTG
TGGGTGAAAGGTGGACATTT

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKRLLIVEDDLSLASILGRRLTRHGFECRLTHDASDALLVAREFRPSHILLDMKLAEANGLGLIVPLRNLLPKVTMVLLT
GYASIATAVEAIRLGADNYLAKPVDTQTLLAALEMEGHSHTLQEDEVDDSPLNPKRLEWEHIQQVLNANQGNVSATARQL
GMHRRTLQRKLLKKPVGESGHLK

Sequences:

>Translated_183_residues
MKRLLIVEDDLSLASILGRRLTRHGFECRLTHDASDALLVAREFRPSHILLDMKLAEANGLGLIVPLRNLLPKVTMVLLT
GYASIATAVEAIRLGADNYLAKPVDTQTLLAALEMEGHSHTLQEDEVDDSPLNPKRLEWEHIQQVLNANQGNVSATARQL
GMHRRTLQRKLLKKPVGESGHLK
>Mature_183_residues
MKRLLIVEDDLSLASILGRRLTRHGFECRLTHDASDALLVAREFRPSHILLDMKLAEANGLGLIVPLRNLLPKVTMVLLT
GYASIATAVEAIRLGADNYLAKPVDTQTLLAALEMEGHSHTLQEDEVDDSPLNPKRLEWEHIQQVLNANQGNVSATARQL
GMHRRTLQRKLLKKPVGESGHLK

Specific function: Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response [H]

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=35, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=31.1926605504587, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20345; Mature: 20345

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLIVEDDLSLASILGRRLTRHGFECRLTHDASDALLVAREFRPSHILLDMKLAEANG
CCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEHHHCCCCEEEEEEEEECCCC
LGLIVPLRNLLPKVTMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTLLAALEMEGHSH
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCC
TLQEDEVDDSPLNPKRLEWEHIQQVLNANQGNVSATARQLGMHRRTLQRKLLKKPVGESG
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HLK
CCC
>Mature Secondary Structure
MKRLLIVEDDLSLASILGRRLTRHGFECRLTHDASDALLVAREFRPSHILLDMKLAEANG
CCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEHHHCCCCEEEEEEEEECCCC
LGLIVPLRNLLPKVTMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTLLAALEMEGHSH
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCC
TLQEDEVDDSPLNPKRLEWEHIQQVLNANQGNVSATARQLGMHRRTLQRKLLKKPVGESG
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HLK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]