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The map label for this gene is argS [H]

Identifier: 126176036

GI number: 126176036

Start: 4519500

End: 4521245

Strand: Direct

Name: argS [H]

Synonym: Sbal_3845

Alternate gene names: 126176036

Gene position: 4519500-4521245 (Clockwise)

Preceding gene: 126176035

Following gene: 126176037

Centisome position: 88.14

GC content: 48.45

Gene sequence:

>1746_bases
ATGAAATCACATATCCAATCATTACTTGAACAAACTCTAGAATCCTTTAAACAACAAGGTATTGTGCCTGCTGACTTTGA
AGCGCGCATTCAGGTAGATCGAACCAAGGATAAGAGTCATGGCGACTTGGCAACCAACTTAGCCATGATGCTGACTAAGG
TCGCGGGCAAGAATCCACGCGAATTAGCCCAACTGATCATCGACACCTTACCGGCTTCGGCTTATGTGGCTAAGGTTGAG
ATCGCAGGTCCTGGCTTTATCAACTTTTTTATCAACGACAGCGCCTTAGCGGATCAACTGCAAAATGCCGTCAACGATGA
GCATTTAGGTATCAAGTTACCGACACCGCAAACCGTTGTTGTTGATTACTCTTCACCAAACCTCGCCAAAGAAATGCACG
TAGGTCACCTACGTTCAACCATCATTGGTGACAGTGTGGTGCGTGCGCTGGAATTTTTAGGCCACAAAGTCATCCGTCAA
AACCATGTGGGCGACTGGGGCACACAATTTGGTATGTTGCTGGCCTACATGGAAGAGCTACGTGCCAAAAATGGTGAGAA
AGCGCAACTTGAACTGTCTGATTTAGAAAACTTTTATCGCGCAGCCAAACTGCGCTTCGACGAATCGGCCGAGTTTGCGA
CCCGCGCTCGTCAATTAGTGGTTGAGTTACAATCTGGCGACGAATATTGCAACAAATTGTGGCGCGAATTTAACGACATT
TCGTTAAGCCACTGCCATGAAGTCTACGCCCGTTTAGGTGTGAGCCTGACCCGCGCCGACGTGCACGGTGAAAGTGCGTA
TAACGCCGATCTCGAGCAAGTAGTTAAAGATTTAGATGCCCAAGGTTTATTAACCGAAAGCAACGGCGCCAAAGTTGTGT
TCCAAGAAGCCTTCCGTAATAAAGAAGGTGAGCCACTGCCAGTGATCATCCAAAAAGCTGATGGTGGCTACTTGTATGCC
ACCTCAGATCTTGCGGCAATGCGCTACCGTTCGAACGTGTTAAAGGCCGATCGCGTACTGTATTTTGTTGACCTACGTCA
GGCGCTGCATTTCCAACAAGTCTTCAGCCTAGCCAAGCTGGCTAAATTTGTTCGTGAAGATATGTCATTGGAACACTTAG
GGTTTGGCACGATGAACGGCGAAGATGGCCGTCCATTCAAAACCCGTAGCGGCGGCGTCGTTAAGTTAGTCGACCTGTTA
GAAGAAGCTAACGTGCGCGCACTTGAACTCGTTCGCAGTAAAAATCCAGATATGGATGAAGCTACGCTGACTGAAATCGC
CCGCGTCGTTGGGATCAGCGCCGTTAAATATGCTGACTTATCGAAAAACCGTACCAGCGATTATATCTTCAGCTTCGAAC
AAATGCTCAGCTTCGAAGGCAATACAGCGCCTTACCTGCTGTACGCTTACACCCGTGTTGCGGGCATCTTCAAGCGCGTA
ACCGATCTGGATTTGAGCCAAGCAAAAATCGTGCTTGAGCATGAAAAAGAGAAAGACCTCGGTAACAAGTTGGCGCAGTT
CGGCGAGATCCTCAGTCGCGTTGTCGATAAAGGCCAACCGCACGTACTGTGTGCTTACCTGTATGAATTAGCGGGTGCTT
TCTCAAGTTTCTACGAAGCGTGCCCCGTGCTTGCTGCCGATAACGACGCGCAAAAGAACAGCCGTTTATTACTCGCACAA
CTGACGGCTCGTACGTTACAAAAAGGCCTAAATCTACTCGGTATCGAAACCTTAGAGCGGATGTAA

Upstream 100 bases:

>100_bases
ATAAAAAATCATCGGGAAGATAGCAATTGTTAACCACAAACGGCTAAAATATGCGGTTATTCCCTGTATTCACTCTTAAA
GTTAGTGCCGATTAGAACCC

Downstream 100 bases:

>100_bases
GCCATGAGTAATCGCGATTATGCCAATAGAAGGCCGCAGTCGGGCGCTAAACCGCGCCCAGTCCGCGCGACTCGCCCAAC
CCGAGCAAAGCCTTCACAAT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MKSHIQSLLEQTLESFKQQGIVPADFEARIQVDRTKDKSHGDLATNLAMMLTKVAGKNPRELAQLIIDTLPASAYVAKVE
IAGPGFINFFINDSALADQLQNAVNDEHLGIKLPTPQTVVVDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFLGHKVIRQ
NHVGDWGTQFGMLLAYMEELRAKNGEKAQLELSDLENFYRAAKLRFDESAEFATRARQLVVELQSGDEYCNKLWREFNDI
SLSHCHEVYARLGVSLTRADVHGESAYNADLEQVVKDLDAQGLLTESNGAKVVFQEAFRNKEGEPLPVIIQKADGGYLYA
TSDLAAMRYRSNVLKADRVLYFVDLRQALHFQQVFSLAKLAKFVREDMSLEHLGFGTMNGEDGRPFKTRSGGVVKLVDLL
EEANVRALELVRSKNPDMDEATLTEIARVVGISAVKYADLSKNRTSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRV
TDLDLSQAKIVLEHEKEKDLGNKLAQFGEILSRVVDKGQPHVLCAYLYELAGAFSSFYEACPVLAADNDAQKNSRLLLAQ
LTARTLQKGLNLLGIETLERM

Sequences:

>Translated_581_residues
MKSHIQSLLEQTLESFKQQGIVPADFEARIQVDRTKDKSHGDLATNLAMMLTKVAGKNPRELAQLIIDTLPASAYVAKVE
IAGPGFINFFINDSALADQLQNAVNDEHLGIKLPTPQTVVVDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFLGHKVIRQ
NHVGDWGTQFGMLLAYMEELRAKNGEKAQLELSDLENFYRAAKLRFDESAEFATRARQLVVELQSGDEYCNKLWREFNDI
SLSHCHEVYARLGVSLTRADVHGESAYNADLEQVVKDLDAQGLLTESNGAKVVFQEAFRNKEGEPLPVIIQKADGGYLYA
TSDLAAMRYRSNVLKADRVLYFVDLRQALHFQQVFSLAKLAKFVREDMSLEHLGFGTMNGEDGRPFKTRSGGVVKLVDLL
EEANVRALELVRSKNPDMDEATLTEIARVVGISAVKYADLSKNRTSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRV
TDLDLSQAKIVLEHEKEKDLGNKLAQFGEILSRVVDKGQPHVLCAYLYELAGAFSSFYEACPVLAADNDAQKNSRLLLAQ
LTARTLQKGLNLLGIETLERM
>Mature_581_residues
MKSHIQSLLEQTLESFKQQGIVPADFEARIQVDRTKDKSHGDLATNLAMMLTKVAGKNPRELAQLIIDTLPASAYVAKVE
IAGPGFINFFINDSALADQLQNAVNDEHLGIKLPTPQTVVVDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFLGHKVIRQ
NHVGDWGTQFGMLLAYMEELRAKNGEKAQLELSDLENFYRAAKLRFDESAEFATRARQLVVELQSGDEYCNKLWREFNDI
SLSHCHEVYARLGVSLTRADVHGESAYNADLEQVVKDLDAQGLLTESNGAKVVFQEAFRNKEGEPLPVIIQKADGGYLYA
TSDLAAMRYRSNVLKADRVLYFVDLRQALHFQQVFSLAKLAKFVREDMSLEHLGFGTMNGEDGRPFKTRSGGVVKLVDLL
EEANVRALELVRSKNPDMDEATLTEIARVVGISAVKYADLSKNRTSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRV
TDLDLSQAKIVLEHEKEKDLGNKLAQFGEILSRVVDKGQPHVLCAYLYELAGAFSSFYEACPVLAADNDAQKNSRLLLAQ
LTARTLQKGLNLLGIETLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=564, Percent_Identity=41.3120567375887, Blast_Score=409, Evalue=1e-114,
Organism=Homo sapiens, GI197100773, Length=538, Percent_Identity=30.8550185873606, Blast_Score=201, Evalue=2e-51,
Organism=Escherichia coli, GI1788184, Length=580, Percent_Identity=54.3103448275862, Blast_Score=637, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=571, Percent_Identity=38.353765323993, Blast_Score=353, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI71985068, Length=530, Percent_Identity=39.811320754717, Blast_Score=346, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI17532153, Length=383, Percent_Identity=30.2872062663185, Blast_Score=158, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6320548, Length=572, Percent_Identity=31.8181818181818, Blast_Score=246, Evalue=8e-66,
Organism=Saccharomyces cerevisiae, GI6321883, Length=563, Percent_Identity=28.9520426287744, Blast_Score=216, Evalue=7e-57,
Organism=Drosophila melanogaster, GI18859963, Length=602, Percent_Identity=38.2059800664452, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI28571570, Length=490, Percent_Identity=32.6530612244898, Blast_Score=204, Evalue=1e-52,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64865; Mature: 64865

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSHIQSLLEQTLESFKQQGIVPADFEARIQVDRTKDKSHGDLATNLAMMLTKVAGKNPR
CHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHH
ELAQLIIDTLPASAYVAKVEIAGPGFINFFINDSALADQLQNAVNDEHLGIKLPTPQTVV
HHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCHHHHHHHHHHCCCCCCEEECCCCCEEE
VDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFLGHKVIRQNHVGDWGTQFGMLLAYMEEL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RAKNGEKAQLELSDLENFYRAAKLRFDESAEFATRARQLVVELQSGDEYCNKLWREFNDI
HHCCCCCEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
SLSHCHEVYARLGVSLTRADVHGESAYNADLEQVVKDLDAQGLLTESNGAKVVFQEAFRN
CHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCEEEEHHHHCC
KEGEPLPVIIQKADGGYLYATSDLAAMRYRSNVLKADRVLYFVDLRQALHFQQVFSLAKL
CCCCCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKFVREDMSLEHLGFGTMNGEDGRPFKTRSGGVVKLVDLLEEANVRALELVRSKNPDMDE
HHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCH
ATLTEIARVVGISAVKYADLSKNRTSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRV
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
TDLDLSQAKIVLEHEKEKDLGNKLAQFGEILSRVVDKGQPHVLCAYLYELAGAFSSFYEA
HCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
CPVLAADNDAQKNSRLLLAQLTARTLQKGLNLLGIETLERM
CCCEECCCCCCCCCHHHHHHHHHHHHHHCCCEECHHHHHCC
>Mature Secondary Structure
MKSHIQSLLEQTLESFKQQGIVPADFEARIQVDRTKDKSHGDLATNLAMMLTKVAGKNPR
CHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHH
ELAQLIIDTLPASAYVAKVEIAGPGFINFFINDSALADQLQNAVNDEHLGIKLPTPQTVV
HHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCHHHHHHHHHHCCCCCCEEECCCCCEEE
VDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFLGHKVIRQNHVGDWGTQFGMLLAYMEEL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RAKNGEKAQLELSDLENFYRAAKLRFDESAEFATRARQLVVELQSGDEYCNKLWREFNDI
HHCCCCCEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
SLSHCHEVYARLGVSLTRADVHGESAYNADLEQVVKDLDAQGLLTESNGAKVVFQEAFRN
CHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCEEEEHHHHCC
KEGEPLPVIIQKADGGYLYATSDLAAMRYRSNVLKADRVLYFVDLRQALHFQQVFSLAKL
CCCCCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKFVREDMSLEHLGFGTMNGEDGRPFKTRSGGVVKLVDLLEEANVRALELVRSKNPDMDE
HHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCH
ATLTEIARVVGISAVKYADLSKNRTSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRV
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
TDLDLSQAKIVLEHEKEKDLGNKLAQFGEILSRVVDKGQPHVLCAYLYELAGAFSSFYEA
HCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
CPVLAADNDAQKNSRLLLAQLTARTLQKGLNLLGIETLERM
CCCEECCCCCCCCCHHHHHHHHHHHHHHCCCEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA