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The map label for this gene is csrD [H]

Identifier: 126176031

GI number: 126176031

Start: 4511680

End: 4513623

Strand: Reverse

Name: csrD [H]

Synonym: Sbal_3840

Alternate gene names: 126176031

Gene position: 4513623-4511680 (Counterclockwise)

Preceding gene: 126176032

Following gene: 126176030

Centisome position: 88.03

GC content: 44.03

Gene sequence:

>1944_bases
ATGAAATTCACCCGAATGTTAACTACAAAATTAACCAGCTTTTGGTTAATGTCATTAGCAGCTATTGCCTTCGTATTTTT
GCTGAGCGCTATGATGAGTTTCGTGCAGCTGACCTATAAATTTCAGCAGCAAAAAGTCGCCGAACTCGAAACTATGTTAG
TGGACCAATATCAACACCAACCCGATTGGGATTTGGAGGCTTGGCTGCCGCCCATGCTGCTCGCCTACAATGCTGTTGAT
TTTCGGCTGACCTTGAAAGATGAAGTGATCTTTGCCTATGAAGGCAATCTCACTTCGCAAAATGCCATGGTGTATGACCA
TGTGTTAGATCCAAAATCTGGTCTGCGCATGCAGCTGACTTTGACTCAACCCTTCGAGCATTACACTTTTAGTTGGTATG
AAATCCTGATCCTGTTGGTCGGTGTGTTAGCTGTGGCTGCCTTAGTGCGTTTTGGCTATTTATGGTTTTCCCAGCAATTG
GATGGCATTGAAGAATTAGCCTTACGCAGTCGATTGATTCTGCAAGGTAAGCACGAGCAAGCACTCGCGACTCCCGGAAA
TGGCAAGCCAAGGCTGATTAACCGTGCTTTGACCAAGTTGTTAGAAGAATTACAAGACGCACAAAAAGAGCGCGGTCGTT
TTGACAAGTTCATTCGTTCTAATACTTTTCTCGATGCGGAAACGCGCATTGGTAATCGACTTTTCTTAAATAACCGTCTC
GACGCCCTTAGCCATAATCAGGCGATGCTCGCCCATGGGGTGATTTATTTATTAGAGATGGATGATCTGGATTTACTGCA
GCAATCCCAAGGTGAAGCGGTAACCAAAGAGTTATTAAACTCGACTGTTAACGCGATAAGCCAATTACTGCAAACCCAAG
CCAACAGTATTTTTGCCCGTCGTTCCCACAATCAATTTGCCATAGTCGTGCCGCAAATCTCGTTAATCGAAGCCGACCAA
TTTGCCAGTAAGTTGCTTAAGATATGTTTGAGCCAGCCGTTACCCGAAGTCGAGAATACCGATAACTTTTTCCACCTCGG
ATGCGCTTATTTTACCGCGGGCGACAATGCAGCGCAGTTAATTGAAGAAGCCGATATGGCTTTGAGGGCGGCACAATTAC
AGGGTAACAGTAATTGGTTTATGTACGACAAAGGCGCGATTGATGAAGAGTTTGCTAAAGGCTCGGTGCGTTGGCGTAGC
TTTTTAGAAAACGCATTAGTGCAACGGCGATTCTTCCCCTTTAGCCAGCCGATAATTGATTCAGATGGTAATGAGCACCA
TAAAGAGATATTTACTCGGGCGCGGGATAATCAAGGAGCGTTAATTCGTGCCACACTGTTTATTCCAATGGCGAATAAAT
GTGGTTTAATGCCGCAAGTCGAACGGCAAATTATTGAGCGGGTATTATTGTTACTGTCGAATGAATTATCGGACGGCGTG
TCGAATACTCAAAAAAATAAGAAATCAGCGCCACAGATATACAGTATTAATCTGAGTTTGGATTCGCTAATGAGTCGAGC
TTTTACCCAATGGCTAAAAACGACGCTGTTAGAATATCGCCATCTGACCACGCGACTGATTTTCGAAGTGTCGGAAGATA
TTGTTATTCAACATCAAGAAAAGTTACAGCCTAAATTAGATATGATCCGTAAAATGGGCGCGAGATTATGCGTCGATCAT
GTAGGCCAGCAGGTCGTTGGCACTTACTATATTCGTGAATGTCATTTTGATTTAATTAAGCTACATAGATCGATTGTGCG
GCATATTCATTTACGCCCAGAAAACCAATTATTCATTCGTAGCTTGATTGGCGGTTTGTATCGAACGGAAGTGCAAGTTT
GTGCCGAAGGGATTGAAGTCTTCGAAGAATGGCAGACACTGCAAATCCTCGGCGTTGGCGCAGCGCAGGGAATGTATTTC
AGTGAACCCATTGAAGCTAAGTAA

Upstream 100 bases:

>100_bases
GCCTTTTAGGTTATGCTACTGAATAATCAACGGACAACTTTGTTGTACTCCTGTTAAAATCGCACAAATAATTATAATAA
TCCTGCAGGATAGCGGATAG

Downstream 100 bases:

>100_bases
GGCAAGTGCGGTATTTGGGTGACTAATGTCGTCTTAGAGACAAATAGATCCTATTATTCACGTATTTATCTATAAAATAC
GAGTATTTGCAGCTAAACTA

Product: regulatory protein CsrD

Products: NA

Alternate protein names: Regulator of CsrB and CsrC decay CsrD [H]

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MKFTRMLTTKLTSFWLMSLAAIAFVFLLSAMMSFVQLTYKFQQQKVAELETMLVDQYQHQPDWDLEAWLPPMLLAYNAVD
FRLTLKDEVIFAYEGNLTSQNAMVYDHVLDPKSGLRMQLTLTQPFEHYTFSWYEILILLVGVLAVAALVRFGYLWFSQQL
DGIEELALRSRLILQGKHEQALATPGNGKPRLINRALTKLLEELQDAQKERGRFDKFIRSNTFLDAETRIGNRLFLNNRL
DALSHNQAMLAHGVIYLLEMDDLDLLQQSQGEAVTKELLNSTVNAISQLLQTQANSIFARRSHNQFAIVVPQISLIEADQ
FASKLLKICLSQPLPEVENTDNFFHLGCAYFTAGDNAAQLIEEADMALRAAQLQGNSNWFMYDKGAIDEEFAKGSVRWRS
FLENALVQRRFFPFSQPIIDSDGNEHHKEIFTRARDNQGALIRATLFIPMANKCGLMPQVERQIIERVLLLLSNELSDGV
SNTQKNKKSAPQIYSINLSLDSLMSRAFTQWLKTTLLEYRHLTTRLIFEVSEDIVIQHQEKLQPKLDMIRKMGARLCVDH
VGQQVVGTYYIRECHFDLIKLHRSIVRHIHLRPENQLFIRSLIGGLYRTEVQVCAEGIEVFEEWQTLQILGVGAAQGMYF
SEPIEAK

Sequences:

>Translated_647_residues
MKFTRMLTTKLTSFWLMSLAAIAFVFLLSAMMSFVQLTYKFQQQKVAELETMLVDQYQHQPDWDLEAWLPPMLLAYNAVD
FRLTLKDEVIFAYEGNLTSQNAMVYDHVLDPKSGLRMQLTLTQPFEHYTFSWYEILILLVGVLAVAALVRFGYLWFSQQL
DGIEELALRSRLILQGKHEQALATPGNGKPRLINRALTKLLEELQDAQKERGRFDKFIRSNTFLDAETRIGNRLFLNNRL
DALSHNQAMLAHGVIYLLEMDDLDLLQQSQGEAVTKELLNSTVNAISQLLQTQANSIFARRSHNQFAIVVPQISLIEADQ
FASKLLKICLSQPLPEVENTDNFFHLGCAYFTAGDNAAQLIEEADMALRAAQLQGNSNWFMYDKGAIDEEFAKGSVRWRS
FLENALVQRRFFPFSQPIIDSDGNEHHKEIFTRARDNQGALIRATLFIPMANKCGLMPQVERQIIERVLLLLSNELSDGV
SNTQKNKKSAPQIYSINLSLDSLMSRAFTQWLKTTLLEYRHLTTRLIFEVSEDIVIQHQEKLQPKLDMIRKMGARLCVDH
VGQQVVGTYYIRECHFDLIKLHRSIVRHIHLRPENQLFIRSLIGGLYRTEVQVCAEGIEVFEEWQTLQILGVGAAQGMYF
SEPIEAK
>Mature_647_residues
MKFTRMLTTKLTSFWLMSLAAIAFVFLLSAMMSFVQLTYKFQQQKVAELETMLVDQYQHQPDWDLEAWLPPMLLAYNAVD
FRLTLKDEVIFAYEGNLTSQNAMVYDHVLDPKSGLRMQLTLTQPFEHYTFSWYEILILLVGVLAVAALVRFGYLWFSQQL
DGIEELALRSRLILQGKHEQALATPGNGKPRLINRALTKLLEELQDAQKERGRFDKFIRSNTFLDAETRIGNRLFLNNRL
DALSHNQAMLAHGVIYLLEMDDLDLLQQSQGEAVTKELLNSTVNAISQLLQTQANSIFARRSHNQFAIVVPQISLIEADQ
FASKLLKICLSQPLPEVENTDNFFHLGCAYFTAGDNAAQLIEEADMALRAAQLQGNSNWFMYDKGAIDEEFAKGSVRWRS
FLENALVQRRFFPFSQPIIDSDGNEHHKEIFTRARDNQGALIRATLFIPMANKCGLMPQVERQIIERVLLLLSNELSDGV
SNTQKNKKSAPQIYSINLSLDSLMSRAFTQWLKTTLLEYRHLTTRLIFEVSEDIVIQHQEKLQPKLDMIRKMGARLCVDH
VGQQVVGTYYIRECHFDLIKLHRSIVRHIHLRPENQLFIRSLIGGLYRTEVQVCAEGIEVFEEWQTLQILGVGAAQGMYF
SEPIEAK

Specific function: Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility ge

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=654, Percent_Identity=28.2874617737003, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI87081845, Length=266, Percent_Identity=24.4360902255639, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1787541, Length=438, Percent_Identity=23.2876712328767, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788849, Length=252, Percent_Identity=25, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081921, Length=445, Percent_Identity=22.247191011236, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790496, Length=242, Percent_Identity=23.5537190082645, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI226510982, Length=303, Percent_Identity=25.0825082508251, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 74235; Mature: 74235

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTRMLTTKLTSFWLMSLAAIAFVFLLSAMMSFVQLTYKFQQQKVAELETMLVDQYQHQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDWDLEAWLPPMLLAYNAVDFRLTLKDEVIFAYEGNLTSQNAMVYDHVLDPKSGLRMQLT
CCCCHHHHCCHHHHHHCCEEEEEEEECCEEEEEECCCCCCCCEEEHHHCCCCCCCEEEEE
LTQPFEHYTFSWYEILILLVGVLAVAALVRFGYLWFSQQLDGIEELALRSRLILQGKHEQ
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCC
ALATPGNGKPRLINRALTKLLEELQDAQKERGRFDKFIRSNTFLDAETRIGNRLFLNNRL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEECCCH
DALSHNQAMLAHGVIYLLEMDDLDLLQQSQGEAVTKELLNSTVNAISQLLQTQANSIFAR
HHHCCCHHHHHCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSHNQFAIVVPQISLIEADQFASKLLKICLSQPLPEVENTDNFFHLGCAYFTAGDNAAQL
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCHHHHH
IEEADMALRAAQLQGNSNWFMYDKGAIDEEFAKGSVRWRSFLENALVQRRFFPFSQPIID
HHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCC
SDGNEHHKEIFTRARDNQGALIRATLFIPMANKCGLMPQVERQIIERVLLLLSNELSDGV
CCCCHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
SNTQKNKKSAPQIYSINLSLDSLMSRAFTQWLKTTLLEYRHLTTRLIFEVSEDIVIQHQE
HHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLQPKLDMIRKMGARLCVDHVGQQVVGTYYIRECHFDLIKLHRSIVRHIHLRPENQLFIR
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SLIGGLYRTEVQVCAEGIEVFEEWQTLQILGVGAAQGMYFSEPIEAK
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCCC
>Mature Secondary Structure
MKFTRMLTTKLTSFWLMSLAAIAFVFLLSAMMSFVQLTYKFQQQKVAELETMLVDQYQHQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDWDLEAWLPPMLLAYNAVDFRLTLKDEVIFAYEGNLTSQNAMVYDHVLDPKSGLRMQLT
CCCCHHHHCCHHHHHHCCEEEEEEEECCEEEEEECCCCCCCCEEEHHHCCCCCCCEEEEE
LTQPFEHYTFSWYEILILLVGVLAVAALVRFGYLWFSQQLDGIEELALRSRLILQGKHEQ
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCC
ALATPGNGKPRLINRALTKLLEELQDAQKERGRFDKFIRSNTFLDAETRIGNRLFLNNRL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEECCCH
DALSHNQAMLAHGVIYLLEMDDLDLLQQSQGEAVTKELLNSTVNAISQLLQTQANSIFAR
HHHCCCHHHHHCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSHNQFAIVVPQISLIEADQFASKLLKICLSQPLPEVENTDNFFHLGCAYFTAGDNAAQL
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCHHHHH
IEEADMALRAAQLQGNSNWFMYDKGAIDEEFAKGSVRWRSFLENALVQRRFFPFSQPIID
HHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCC
SDGNEHHKEIFTRARDNQGALIRATLFIPMANKCGLMPQVERQIIERVLLLLSNELSDGV
CCCCHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
SNTQKNKKSAPQIYSINLSLDSLMSRAFTQWLKTTLLEYRHLTTRLIFEVSEDIVIQHQE
HHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLQPKLDMIRKMGARLCVDHVGQQVVGTYYIRECHFDLIKLHRSIVRHIHLRPENQLFIR
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SLIGGLYRTEVQVCAEGIEVFEEWQTLQILGVGAAQGMYFSEPIEAK
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 3049542 [H]