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The map label for this gene is dipZ [H]

Identifier: 126175920

GI number: 126175920

Start: 4359396

End: 4361255

Strand: Direct

Name: dipZ [H]

Synonym: Sbal_3726

Alternate gene names: 126175920

Gene position: 4359396-4361255 (Clockwise)

Preceding gene: 126175919

Following gene: 126175921

Centisome position: 85.02

GC content: 49.57

Gene sequence:

>1860_bases
ATGAAAAAACTACTCAGCCTTATTTTTACGTCTTTATTGCTCCTCACGCCCTTAGCGCACAGTGAAGGGGTTTTCGGTAA
CAAATTCGACTTCATGAAGAGTGAGCCGGAATTGATGCCTGTCGATCAAGCATTTGCCTTCGATTTTAAGCAAGAAGGTA
ATCAGGTCAAACTCAATTGGGTGATTGCCGACGGTTACTACATGTACCGCGACAAGCTTAAATTTACTGTCAATGGCGCC
GAGCTAGGCACAGTGGCGCTGCCCAAGGGCAAGCCCCATGAAGATGAGTATTTTGGCGAGCAAGAAGTCTATTACACCTA
TGTGGATATTCCCGTTGCGCTGAAACAGGCCGATGAAAATGCCACGCTTACCGTCACTTTTATGGGCTGCGCCGAAGGCA
AGTTGTGTTATCCACCGACCAAACGTGACGTGGTGCTAAAAGCGATTGCCGCCAACGATGGGTTAATCGCAGGTGCCGAA
GCGAGCGAATCGACCGCCGCAGCAAAGCCAGCAAGCACTGAGTCAGCCAGCATTGAACCGAGCACGGCCGATAAAGCCAA
TACCCAACCTATTACTCAGCAAGATACCCTGAGCCAAATGCTGTCAAACGACAGCCTGATTTGGACCTTATTGATCTTCT
TTGGTCTAGGTGTCGGTCTGGCATTAACGCCTTGCGTGTTCCCTATGTACCCGATTTTGTCAGGCATTATTGTCGGCCAA
GGGCAAAAACTCTCAACCGCGAAAGCCTTTACCTTGTCTATGGCTTACGTGCAAGGCATGGCAATCACTTACTCTATCTT
AGGGTTAGTAGTCGCATCGGCGGGACTGAAATACCAAGCGGCGTTACAACATCCCGCCGTGTTAGTGGTGCTCGCTATCC
TGTTCTTTGTGCTCAGCTTATCTATGTTTGGCCTGTACGATTTGAAACTGCCATCGAGCTGGCAGGAGAAGATGAACTCA
GTATCGAACAACCAAAAAGGCGGCAACTTAGTTGGCGTATTCTTGATGGGCGTGATTTCTGGCCTGGTCGCATCACCTTG
TACTACCGCGCCGCTATCGGGTGCGCTCGTTTATGTGGCGCAAACCGGCGACTTACTCCAAGGCTTCTTAGCCCTGTATG
TGCTCAGTATGGGCATGGGTTTACCTCTGCTGATTATCGGCACCTCGGGCGGTAAATTATTACCCAGAGCGGGCGCTTGG
ATGGACATCATCAAGACCGTCTTCGGCTTCCTGTTGATCGCTGTGTCTATCGTAATGCTCGGTCGTATTTGGACGGGCGT
GGTATCCGATGTGCTTTGGTCACTGTGGGGCGTGAGCTTCACCGGCTACTTGATGCATCAGAACAAACTCAGTCCCTTCA
ACTGGAAACAGACTGTCCGTTCAGTGCTATTAACTCTGACGCTACTGGCAAGTTTCTCCTACGGATTCCAAGCTGTGATG
GGCCACTTTGGTTTTAATCACAATCCCGTAGGCACCGCGGCGACGACCGAAGAAGCCCATGGCTTTAAACGGATTAAATC
CATTAAAGATCTTGATCAAGAAATCGCCGCCGCTGCCGCCCAAGGTAAGCCTGTGATGCTGGATCTCTATGCCGATTGGT
GTGTTGCCTGTAAAGAGTTTGAAGCCATCACCTTTAAGGATGCCGACGTGTTAGCCCGCATGAATAAAATCGTGCTGCTG
CAAGCCGATGTGACTAAGAGTGACAAGGTCGATGTGGCCTTACTCGAAAAATACAATGTGCTCGGTTTGCCTACGTTGTT
GATGTTTAACGAACAAGGTGAGCAAAGGGAAGATTTACGAGTGACTGGTTTTATGGGTCCTAAAGATTTTGCCGCCCATT
TAGATCATCTGGTGAAATAG

Upstream 100 bases:

>100_bases
TGCTTAGACTTCACCCTTATCAAGTACCCGAAATTATTGCCGTGCCTGTGACTCACGGGCTACCAGCCTACTTAGATTGG
ATAAAAGACAACACTCAGCC

Downstream 100 bases:

>100_bases
TCACGATTTAGACTTAGACCACAAAAGCGATTTAACTCGCGCCGGTTTTAACCAGCAAGTGTATTTGCCGCAACACCAAT
AGAAAGCGGACTTTTTTCAT

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MKKLLSLIFTSLLLLTPLAHSEGVFGNKFDFMKSEPELMPVDQAFAFDFKQEGNQVKLNWVIADGYYMYRDKLKFTVNGA
ELGTVALPKGKPHEDEYFGEQEVYYTYVDIPVALKQADENATLTVTFMGCAEGKLCYPPTKRDVVLKAIAANDGLIAGAE
ASESTAAAKPASTESASIEPSTADKANTQPITQQDTLSQMLSNDSLIWTLLIFFGLGVGLALTPCVFPMYPILSGIIVGQ
GQKLSTAKAFTLSMAYVQGMAITYSILGLVVASAGLKYQAALQHPAVLVVLAILFFVLSLSMFGLYDLKLPSSWQEKMNS
VSNNQKGGNLVGVFLMGVISGLVASPCTTAPLSGALVYVAQTGDLLQGFLALYVLSMGMGLPLLIIGTSGGKLLPRAGAW
MDIIKTVFGFLLIAVSIVMLGRIWTGVVSDVLWSLWGVSFTGYLMHQNKLSPFNWKQTVRSVLLTLTLLASFSYGFQAVM
GHFGFNHNPVGTAATTEEAHGFKRIKSIKDLDQEIAAAAAQGKPVMLDLYADWCVACKEFEAITFKDADVLARMNKIVLL
QADVTKSDKVDVALLEKYNVLGLPTLLMFNEQGEQREDLRVTGFMGPKDFAAHLDHLVK

Sequences:

>Translated_619_residues
MKKLLSLIFTSLLLLTPLAHSEGVFGNKFDFMKSEPELMPVDQAFAFDFKQEGNQVKLNWVIADGYYMYRDKLKFTVNGA
ELGTVALPKGKPHEDEYFGEQEVYYTYVDIPVALKQADENATLTVTFMGCAEGKLCYPPTKRDVVLKAIAANDGLIAGAE
ASESTAAAKPASTESASIEPSTADKANTQPITQQDTLSQMLSNDSLIWTLLIFFGLGVGLALTPCVFPMYPILSGIIVGQ
GQKLSTAKAFTLSMAYVQGMAITYSILGLVVASAGLKYQAALQHPAVLVVLAILFFVLSLSMFGLYDLKLPSSWQEKMNS
VSNNQKGGNLVGVFLMGVISGLVASPCTTAPLSGALVYVAQTGDLLQGFLALYVLSMGMGLPLLIIGTSGGKLLPRAGAW
MDIIKTVFGFLLIAVSIVMLGRIWTGVVSDVLWSLWGVSFTGYLMHQNKLSPFNWKQTVRSVLLTLTLLASFSYGFQAVM
GHFGFNHNPVGTAATTEEAHGFKRIKSIKDLDQEIAAAAAQGKPVMLDLYADWCVACKEFEAITFKDADVLARMNKIVLL
QADVTKSDKVDVALLEKYNVLGLPTLLMFNEQGEQREDLRVTGFMGPKDFAAHLDHLVK
>Mature_619_residues
MKKLLSLIFTSLLLLTPLAHSEGVFGNKFDFMKSEPELMPVDQAFAFDFKQEGNQVKLNWVIADGYYMYRDKLKFTVNGA
ELGTVALPKGKPHEDEYFGEQEVYYTYVDIPVALKQADENATLTVTFMGCAEGKLCYPPTKRDVVLKAIAANDGLIAGAE
ASESTAAAKPASTESASIEPSTADKANTQPITQQDTLSQMLSNDSLIWTLLIFFGLGVGLALTPCVFPMYPILSGIIVGQ
GQKLSTAKAFTLSMAYVQGMAITYSILGLVVASAGLKYQAALQHPAVLVVLAILFFVLSLSMFGLYDLKLPSSWQEKMNS
VSNNQKGGNLVGVFLMGVISGLVASPCTTAPLSGALVYVAQTGDLLQGFLALYVLSMGMGLPLLIIGTSGGKLLPRAGAW
MDIIKTVFGFLLIAVSIVMLGRIWTGVVSDVLWSLWGVSFTGYLMHQNKLSPFNWKQTVRSVLLTLTLLASFSYGFQAVM
GHFGFNHNPVGTAATTEEAHGFKRIKSIKDLDQEIAAAAAQGKPVMLDLYADWCVACKEFEAITFKDADVLARMNKIVLL
QADVTKSDKVDVALLEKYNVLGLPTLLMFNEQGEQREDLRVTGFMGPKDFAAHLDHLVK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=607, Percent_Identity=45.4695222405272, Blast_Score=512, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 67159; Mature: 67159

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLSLIFTSLLLLTPLAHSEGVFGNKFDFMKSEPELMPVDQAFAFDFKQEGNQVKLNW
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEE
VIADGYYMYRDKLKFTVNGAELGTVALPKGKPHEDEYFGEQEVYYTYVDIPVALKQADEN
EEECCEEEEEEEEEEEECCCCCCEEECCCCCCCCHHHCCCCEEEEEEEECEEEEEECCCC
ATLTVTFMGCAEGKLCYPPTKRDVVLKAIAANDGLIAGAEASESTAAAKPASTESASIEP
CEEEEEEEECCCCCEECCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCC
STADKANTQPITQQDTLSQMLSNDSLIWTLLIFFGLGVGLALTPCVFPMYPILSGIIVGQ
CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECC
GQKLSTAKAFTLSMAYVQGMAITYSILGLVVASAGLKYQAALQHPAVLVVLAILFFVLSL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHH
SMFGLYDLKLPSSWQEKMNSVSNNQKGGNLVGVFLMGVISGLVASPCTTAPLSGALVYVA
HHHCEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
QTGDLLQGFLALYVLSMGMGLPLLIIGTSGGKLLPRAGAWMDIIKTVFGFLLIAVSIVML
CCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GRIWTGVVSDVLWSLWGVSFTGYLMHQNKLSPFNWKQTVRSVLLTLTLLASFSYGFQAVM
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GHFGFNHNPVGTAATTEEAHGFKRIKSIKDLDQEIAAAAAQGKPVMLDLYADWCVACKEF
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHC
EAITFKDADVLARMNKIVLLQADVTKSDKVDVALLEKYNVLGLPTLLMFNEQGEQREDLR
CEEEECCHHHHHHCCEEEEEEECCCCCCCCCEEEHHCCCCCCCCEEEEECCCCCCCCCCE
VTGFMGPKDFAAHLDHLVK
EEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKKLLSLIFTSLLLLTPLAHSEGVFGNKFDFMKSEPELMPVDQAFAFDFKQEGNQVKLNW
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEE
VIADGYYMYRDKLKFTVNGAELGTVALPKGKPHEDEYFGEQEVYYTYVDIPVALKQADEN
EEECCEEEEEEEEEEEECCCCCCEEECCCCCCCCHHHCCCCEEEEEEEECEEEEEECCCC
ATLTVTFMGCAEGKLCYPPTKRDVVLKAIAANDGLIAGAEASESTAAAKPASTESASIEP
CEEEEEEEECCCCCEECCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCC
STADKANTQPITQQDTLSQMLSNDSLIWTLLIFFGLGVGLALTPCVFPMYPILSGIIVGQ
CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECC
GQKLSTAKAFTLSMAYVQGMAITYSILGLVVASAGLKYQAALQHPAVLVVLAILFFVLSL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHH
SMFGLYDLKLPSSWQEKMNSVSNNQKGGNLVGVFLMGVISGLVASPCTTAPLSGALVYVA
HHHCEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
QTGDLLQGFLALYVLSMGMGLPLLIIGTSGGKLLPRAGAWMDIIKTVFGFLLIAVSIVML
CCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GRIWTGVVSDVLWSLWGVSFTGYLMHQNKLSPFNWKQTVRSVLLTLTLLASFSYGFQAVM
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GHFGFNHNPVGTAATTEEAHGFKRIKSIKDLDQEIAAAAAQGKPVMLDLYADWCVACKEF
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHC
EAITFKDADVLARMNKIVLLQADVTKSDKVDVALLEKYNVLGLPTLLMFNEQGEQREDLR
CEEEECCHHHHHHCCEEEEEEECCCCCCCCCEEEHHCCCCCCCCEEEEECCCCCCCCCCE
VTGFMGPKDFAAHLDHLVK
EEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA