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The map label for this gene is degQ [H]

Identifier: 126175849

GI number: 126175849

Start: 4276474

End: 4277826

Strand: Direct

Name: degQ [H]

Synonym: Sbal_3654

Alternate gene names: 126175849

Gene position: 4276474-4277826 (Clockwise)

Preceding gene: 126175840

Following gene: 126175850

Centisome position: 83.4

GC content: 48.48

Gene sequence:

>1353_bases
ATGAAAACAAAATTATCTGTACTTTCAGCCGCAATGTTAGCCGCGACCCTGACTATGATGCCTGTCGTCTCACAGGCCGC
CATTCCACAGACGGTTGAGGGACAATCCATTCCAAGTCTTGCGCCCATGCTTGAGCGTACGACACCTGCTGTTGTGTCCG
TAGCCGTTACGGGTACTCATGTTTCAAAACAAAGAGTACCTGATGTTTTCCGTTACTTCTTTGGCCCCAATGCGCCACAG
GAGCAAGTGCAGGAACGTCCTTTTAGAGGCTTAGGCTCAGGCGTTATTATTGACGCCGAAAAAGGCTACATAGTCACTAA
CAACCACGTGATTGACGGTGCTGATGATATTCAAGTTGGTCTACATGACGGTCGTGAAGTAAAGGCCAAACTCATTGGTA
CTGACTCAGAATCGGATATTGCATTGCTGCAAATTGAGGCAAAAAATCTTGTCGCAATCAAGTCATCAAACTCTGACGAC
TTGCGTGTTGGTGACTTTGCCGTTGCCATTGGTAACCCCTTCGGTTTAGGGCAAACCGTGACTTCAGGTATTGTCAGTGC
TTTAGGCCGTAGCGGTTTAGGCATAGAAATGCTGGAAAACTTTATTCAAACCGATGCCGCGATTAACAGTGGTAACTCGG
GTGGTGCACTCGTTAACTTAAACGGGGAATTGATTGGGATTAACACCGCAATCGTAGCGCCGGGGGGTGGTAACGTTGGT
ATCGGCTTTGCGATCCCAGCCAATATGGTGAAAAACTTGGTCGCGCAAATTGCCGAACACGGTGAAGTACGCCGCGGAGT
ACTGGGGATTTCGGGACGCGATCTTGATAGCCAACTCGCCCAAGGCTTTGGTTTAGACACCCAGCACGGCGGCTTCGTGA
ATGAAGTAGCCAAAGACAGTGCCGCCGAAAAAGCCGGTATTAAAGCGGGTGATATCATTATCAGCGTCGATGGCCGTGGT
ATTAAGTCCTTCCAAGAACTGCGAGCCAAAGTCGCCACTATGGGTGCGGGTGCTAAGGTTGAGTTAGGACTCATCCGTGA
CGGAGATAAGAAAACCGTTAAGGTGACCTTAGGTGAAGCAAGCCAAACCAGTGAATCTGCGGCTGGCGCCGTGCATCCTA
TGTTGCAAGGTGCATCCTTAGAAAACACATCTAAGGGCATTGAAATTACCGATGTCGCCCAAGGTTCACCAGCGGCAATG
AGTGGCTTACAAAAAGGAGATGTGATTGTCGGTATTAACCGTACTGCAATTAAAGATCTTAAGGCACTTAAAGCACAGCT
AAAAGATCAAGAAGGTGCGGTGGCACTGAAGATCATGCGTGATAAGAGCATGTTGTATTTAGTCCTACGTTAA

Upstream 100 bases:

>100_bases
AGGCAAATAGCCGGTACCGATACAGATTTGATCTGGCACTCGCACAATAGCTGATGCATTACATCCAGATCGTTCAACCC
TTATTTGGAGTTATGAATAG

Downstream 100 bases:

>100_bases
TCGACTAAATAGGTCATTTTTTCTGCCACACATAAGCATAGGGAGCTTAGGTTCCCTATACTTACATAGATTAAACATGT
TAATCTAACTCACCTTTTTC

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MKTKLSVLSAAMLAATLTMMPVVSQAAIPQTVEGQSIPSLAPMLERTTPAVVSVAVTGTHVSKQRVPDVFRYFFGPNAPQ
EQVQERPFRGLGSGVIIDAEKGYIVTNNHVIDGADDIQVGLHDGREVKAKLIGTDSESDIALLQIEAKNLVAIKSSNSDD
LRVGDFAVAIGNPFGLGQTVTSGIVSALGRSGLGIEMLENFIQTDAAINSGNSGGALVNLNGELIGINTAIVAPGGGNVG
IGFAIPANMVKNLVAQIAEHGEVRRGVLGISGRDLDSQLAQGFGLDTQHGGFVNEVAKDSAAEKAGIKAGDIIISVDGRG
IKSFQELRAKVATMGAGAKVELGLIRDGDKKTVKVTLGEASQTSESAAGAVHPMLQGASLENTSKGIEITDVAQGSPAAM
SGLQKGDVIVGINRTAIKDLKALKAQLKDQEGAVALKIMRDKSMLYLVLR

Sequences:

>Translated_450_residues
MKTKLSVLSAAMLAATLTMMPVVSQAAIPQTVEGQSIPSLAPMLERTTPAVVSVAVTGTHVSKQRVPDVFRYFFGPNAPQ
EQVQERPFRGLGSGVIIDAEKGYIVTNNHVIDGADDIQVGLHDGREVKAKLIGTDSESDIALLQIEAKNLVAIKSSNSDD
LRVGDFAVAIGNPFGLGQTVTSGIVSALGRSGLGIEMLENFIQTDAAINSGNSGGALVNLNGELIGINTAIVAPGGGNVG
IGFAIPANMVKNLVAQIAEHGEVRRGVLGISGRDLDSQLAQGFGLDTQHGGFVNEVAKDSAAEKAGIKAGDIIISVDGRG
IKSFQELRAKVATMGAGAKVELGLIRDGDKKTVKVTLGEASQTSESAAGAVHPMLQGASLENTSKGIEITDVAQGSPAAM
SGLQKGDVIVGINRTAIKDLKALKAQLKDQEGAVALKIMRDKSMLYLVLR
>Mature_450_residues
MKTKLSVLSAAMLAATLTMMPVVSQAAIPQTVEGQSIPSLAPMLERTTPAVVSVAVTGTHVSKQRVPDVFRYFFGPNAPQ
EQVQERPFRGLGSGVIIDAEKGYIVTNNHVIDGADDIQVGLHDGREVKAKLIGTDSESDIALLQIEAKNLVAIKSSNSDD
LRVGDFAVAIGNPFGLGQTVTSGIVSALGRSGLGIEMLENFIQTDAAINSGNSGGALVNLNGELIGINTAIVAPGGGNVG
IGFAIPANMVKNLVAQIAEHGEVRRGVLGISGRDLDSQLAQGFGLDTQHGGFVNEVAKDSAAEKAGIKAGDIIISVDGRG
IKSFQELRAKVATMGAGAKVELGLIRDGDKKTVKVTLGEASQTSESAAGAVHPMLQGASLENTSKGIEITDVAQGSPAAM
SGLQKGDVIVGINRTAIKDLKALKAQLKDQEGAVALKIMRDKSMLYLVLR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=312, Percent_Identity=35.8974358974359, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI4506141, Length=251, Percent_Identity=39.0438247011952, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI24308541, Length=299, Percent_Identity=32.1070234113712, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI7019477, Length=314, Percent_Identity=33.7579617834395, Blast_Score=137, Evalue=1e-32,
Organism=Escherichia coli, GI1789629, Length=458, Percent_Identity=54.1484716157205, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1786356, Length=440, Percent_Identity=54.0909090909091, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI1789630, Length=334, Percent_Identity=42.5149700598802, Blast_Score=214, Evalue=9e-57,
Organism=Drosophila melanogaster, GI24646839, Length=253, Percent_Identity=36.3636363636364, Blast_Score=132, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 46629; Mature: 46629

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKLSVLSAAMLAATLTMMPVVSQAAIPQTVEGQSIPSLAPMLERTTPAVVSVAVTGTH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEEEEECCC
VSKQRVPDVFRYFFGPNAPQEQVQERPFRGLGSGVIIDAEKGYIVTNNHVIDGADDIQVG
CCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEECCCCEEEECCEEECCCCCEEEE
LHDGREVKAKLIGTDSESDIALLQIEAKNLVAIKSSNSDDLRVGDFAVAIGNPFGLGQTV
CCCCCEEEEEEEECCCCCCEEEEEEECCCEEEEECCCCCCEEECEEEEEECCCCCCCHHH
TSGIVSALGRSGLGIEMLENFIQTDAAINSGNSGGALVNLNGELIGINTAIVAPGGGNVG
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEEEEEECCCCCEE
IGFAIPANMVKNLVAQIAEHGEVRRGVLGISGRDLDSQLAQGFGLDTQHGGFVNEVAKDS
EEEECCHHHHHHHHHHHHHCCHHHHCEEECCCCCHHHHHHHCCCCCCCCCCHHHHHHHHH
AAEKAGIKAGDIIISVDGRGIKSFQELRAKVATMGAGAKVELGLIRDGDKKTVKVTLGEA
HHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEECCC
SQTSESAAGAVHPMLQGASLENTSKGIEITDVAQGSPAAMSGLQKGDVIVGINRTAIKDL
CCCCHHHCCHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHCCCCCCEEEECCHHHHHHH
KALKAQLKDQEGAVALKIMRDKSMLYLVLR
HHHHHHHCCCCCCEEEEEEECCCEEEEEEC
>Mature Secondary Structure
MKTKLSVLSAAMLAATLTMMPVVSQAAIPQTVEGQSIPSLAPMLERTTPAVVSVAVTGTH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEEEEECCC
VSKQRVPDVFRYFFGPNAPQEQVQERPFRGLGSGVIIDAEKGYIVTNNHVIDGADDIQVG
CCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEECCCCEEEECCEEECCCCCEEEE
LHDGREVKAKLIGTDSESDIALLQIEAKNLVAIKSSNSDDLRVGDFAVAIGNPFGLGQTV
CCCCCEEEEEEEECCCCCCEEEEEEECCCEEEEECCCCCCEEECEEEEEECCCCCCCHHH
TSGIVSALGRSGLGIEMLENFIQTDAAINSGNSGGALVNLNGELIGINTAIVAPGGGNVG
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEEEEEECCCCCEE
IGFAIPANMVKNLVAQIAEHGEVRRGVLGISGRDLDSQLAQGFGLDTQHGGFVNEVAKDS
EEEECCHHHHHHHHHHHHHCCHHHHCEEECCCCCHHHHHHHCCCCCCCCCCHHHHHHHHH
AAEKAGIKAGDIIISVDGRGIKSFQELRAKVATMGAGAKVELGLIRDGDKKTVKVTLGEA
HHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEECCC
SQTSESAAGAVHPMLQGASLENTSKGIEITDVAQGSPAAMSGLQKGDVIVGINRTAIKDL
CCCCHHHCCHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHCCCCCCEEEECCHHHHHHH
KALKAQLKDQEGAVALKIMRDKSMLYLVLR
HHHHHHHCCCCCCEEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]