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The map label for this gene is alr [H]

Identifier: 126175832

GI number: 126175832

Start: 4258752

End: 4259828

Strand: Reverse

Name: alr [H]

Synonym: Sbal_3637

Alternate gene names: 126175832

Gene position: 4259828-4258752 (Counterclockwise)

Preceding gene: 126175833

Following gene: 126175830

Centisome position: 83.08

GC content: 50.42

Gene sequence:

>1077_bases
TTGAACCCTTTTCCCCGTGCAGAAATTAGCAGTAGTGCACTGCAAACCAATCTCGCTGCGTTGCGTCAACAGGCTCCAGC
GAGTCGCGTAATGGCCGTCGTTAAAGCGAACGGCTATGGTCATGGATTATTGAATGTCGCTAATTGTTTAGTCAGTGCCG
ATGGCTTTGGCTTAGCACGATTGGATGAAGCCTTAGAATTACGAGCGGGCGGCGTGACAGCGCGGTTGTTATTGCTGGAA
GGTTTTTTCCGCGCCACCGATCTCCCGTTACTCGTCGGGCATGATATCGACACTGTGGTGCATCATAGCTCTCAGCTTGA
GATGTTAGAGCAAACCGTGTTGTCTAAACCTGTGACTGTTTGGCTGAAAGTGGATTCAGGCATGCATCGCTTAGGCTTTA
CGCCTGAGCAATTCTCAACGGTTTACGACCGATTAATGGCCTGTCCCAATGTGGCAAAACCGATTCATTTGATGACGCAT
TTTGCCTGTGCAGATGAGCCAGATAACACTTATACCTCAGTGCAGATGGCGGCTTTTAACTCCTTAACGGCTGGCTTACC
CGGATTTAGAACCTTAGCCAACTCCGCCGGTGCATTGTATTGGCCGCAAAGCCAAGGCGATTGGATCCGTCCGGGAATCG
CACTCTATGGTGTGTCACCTGTCACTGGAGATTGCGGTGCGAATCACGGACTAGTACCTGCGATGGAACTGGTATCACAG
TTGATTGCGGTGCGGGATCATAAAGCCAATCAGCCTGTAGGTTATGGCTGTTTCTGGACCGCGAAGCAAGATACCCGTTT
AGGTGTTGTCGCAATTGGTTATGGTGATGGTTATCCCCGTAATGCACCGGAAGGTACACCCGTGTGGGTCAATGGTCGTC
GCGTACCCATAGTTGGTCGCGTCTCTATGGACATGTTGACTGTCGACCTAGGCCAAGATGCGCAGGATAAGGTTGGCGAT
AGCGCTTTGTTGTGGGGTAAAGCATTACCCGTAGAAGAAGTCGCTGAGCATATTGGTACTATCGCTTATGAATTAGTCAC
TAAGCTCACCCCAAGGGTTGCGGTTTGTTTAGCTTAG

Upstream 100 bases:

>100_bases
TACGTTTGAAAATTGTAAATTTGCGTATGCAGAAGACGTGCTGTGCTGATGTATTTTTTATATCCGTGACTTTTTATTTC
CTGAGTGAGCAAGGTAAATT

Downstream 100 bases:

>100_bases
CTTTGTTAACTTCATCTCGTGAGTTTACTCTCATGAGACTAGCCTGGTGAAATGAACCTCGTTAGCCTGAGCGACTTCAG
CATTAAAAATGCAGAATCAT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MNPFPRAEISSSALQTNLAALRQQAPASRVMAVVKANGYGHGLLNVANCLVSADGFGLARLDEALELRAGGVTARLLLLE
GFFRATDLPLLVGHDIDTVVHHSSQLEMLEQTVLSKPVTVWLKVDSGMHRLGFTPEQFSTVYDRLMACPNVAKPIHLMTH
FACADEPDNTYTSVQMAAFNSLTAGLPGFRTLANSAGALYWPQSQGDWIRPGIALYGVSPVTGDCGANHGLVPAMELVSQ
LIAVRDHKANQPVGYGCFWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGRVSMDMLTVDLGQDAQDKVGD
SALLWGKALPVEEVAEHIGTIAYELVTKLTPRVAVCLA

Sequences:

>Translated_358_residues
MNPFPRAEISSSALQTNLAALRQQAPASRVMAVVKANGYGHGLLNVANCLVSADGFGLARLDEALELRAGGVTARLLLLE
GFFRATDLPLLVGHDIDTVVHHSSQLEMLEQTVLSKPVTVWLKVDSGMHRLGFTPEQFSTVYDRLMACPNVAKPIHLMTH
FACADEPDNTYTSVQMAAFNSLTAGLPGFRTLANSAGALYWPQSQGDWIRPGIALYGVSPVTGDCGANHGLVPAMELVSQ
LIAVRDHKANQPVGYGCFWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGRVSMDMLTVDLGQDAQDKVGD
SALLWGKALPVEEVAEHIGTIAYELVTKLTPRVAVCLA
>Mature_358_residues
MNPFPRAEISSSALQTNLAALRQQAPASRVMAVVKANGYGHGLLNVANCLVSADGFGLARLDEALELRAGGVTARLLLLE
GFFRATDLPLLVGHDIDTVVHHSSQLEMLEQTVLSKPVTVWLKVDSGMHRLGFTPEQFSTVYDRLMACPNVAKPIHLMTH
FACADEPDNTYTSVQMAAFNSLTAGLPGFRTLANSAGALYWPQSQGDWIRPGIALYGVSPVTGDCGANHGLVPAMELVSQ
LIAVRDHKANQPVGYGCFWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGRVSMDMLTVDLGQDAQDKVGD
SALLWGKALPVEEVAEHIGTIAYELVTKLTPRVAVCLA

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=348, Percent_Identity=58.9080459770115, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1787439, Length=352, Percent_Identity=46.0227272727273, Blast_Score=291, Evalue=4e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 38411; Mature: 38411

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFPRAEISSSALQTNLAALRQQAPASRVMAVVKANGYGHGLLNVANCLVSADGFGLAR
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCHHHHHHHHHHCCCCCCHHH
LDEALELRAGGVTARLLLLEGFFRATDLPLLVGHDIDTVVHHSSQLEMLEQTVLSKPVTV
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCHHHHHHCHHHHHHHHHHHHCCCEEE
WLKVDSGMHRLGFTPEQFSTVYDRLMACPNVAKPIHLMTHFACADEPDNTYTSVQMAAFN
EEEECCCCHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHEEEHHHHH
SLTAGLPGFRTLANSAGALYWPQSQGDWIRPGIALYGVSPVTGDCGANHGLVPAMELVSQ
HHHCCCCHHHHHHCCCCEEEECCCCCCEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
LIAVRDHKANQPVGYGCFWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGR
HHHHHCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCCCEEEECCEEEEEEEE
VSMDMLTVDLGQDAQDKVGDSALLWGKALPVEEVAEHIGTIAYELVTKLTPRVAVCLA
CEEEEEEEECCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MNPFPRAEISSSALQTNLAALRQQAPASRVMAVVKANGYGHGLLNVANCLVSADGFGLAR
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCHHHHHHHHHHCCCCCCHHH
LDEALELRAGGVTARLLLLEGFFRATDLPLLVGHDIDTVVHHSSQLEMLEQTVLSKPVTV
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCHHHHHHCHHHHHHHHHHHHCCCEEE
WLKVDSGMHRLGFTPEQFSTVYDRLMACPNVAKPIHLMTHFACADEPDNTYTSVQMAAFN
EEEECCCCHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHEEEHHHHH
SLTAGLPGFRTLANSAGALYWPQSQGDWIRPGIALYGVSPVTGDCGANHGLVPAMELVSQ
HHHCCCCHHHHHHCCCCEEEECCCCCCEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
LIAVRDHKANQPVGYGCFWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGR
HHHHHCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCCCEEEECCEEEEEEEE
VSMDMLTVDLGQDAQDKVGDSALLWGKALPVEEVAEHIGTIAYELVTKLTPRVAVCLA
CEEEEEEEECCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA