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The map label for this gene is umuD [H]

Identifier: 126175750

GI number: 126175750

Start: 4176611

End: 4177018

Strand: Reverse

Name: umuD [H]

Synonym: Sbal_3554

Alternate gene names: 126175750

Gene position: 4177018-4176611 (Counterclockwise)

Preceding gene: 126175760

Following gene: 126175749

Centisome position: 81.47

GC content: 41.91

Gene sequence:

>408_bases
ATGCGTGTTATCCCTATACCTGCCCGTGCTGGTATTACTGGTTTTGAGTCACCTGCTGCTGAATACACTCAACTAGGTCT
AAGTTTGGATGAGTTATTGATTAACCATCCAAGCTCGACTTTTCTCGCCTTTGCAGAAGGGGATTCGATGCAAGGTAAAG
GTATATTTGATGGAGATATACTCATTATTGACCGCCATGAAACAGCGCGTTATGGCGATGTGATTGTTGCCAGTTTAAAT
AGGGAGTTTATTTGCAAAATCATTGATATACCCCGCCGTTTACTGCTTTCCTCCAATCCACAACACCAGCCTGTCATCAT
TCACGAATATGATGAATTTAGTATTGAAGGGGTTATTACTCGTTCTATCCGTTGCCACCGTAAAAGTCCCTTATTGAGTG
AAAAGTAG

Upstream 100 bases:

>100_bases
GAGAAGAACCAATGGTGTTACATTGCGGTCGTTGAATAATTCTTGCTAGCTGCTATTCTACGACTATAATTGCTGTATAT
AATTACAGTGGTTTATTACT

Downstream 100 bases:

>100_bases
ATGTTTGCGCTAGTCGATGCCAATAGCTTCTACTGTAGCGCGGAACAGGTGTTCCGGCCTGATTGGCGTGGTAAGCCTGT
TGTTGTACTCAGTAATAACG

Product: putative prophage repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MRVIPIPARAGITGFESPAAEYTQLGLSLDELLINHPSSTFLAFAEGDSMQGKGIFDGDILIIDRHETARYGDVIVASLN
REFICKIIDIPRRLLLSSNPQHQPVIIHEYDEFSIEGVITRSIRCHRKSPLLSEK

Sequences:

>Translated_135_residues
MRVIPIPARAGITGFESPAAEYTQLGLSLDELLINHPSSTFLAFAEGDSMQGKGIFDGDILIIDRHETARYGDVIVASLN
REFICKIIDIPRRLLLSSNPQHQPVIIHEYDEFSIEGVITRSIRCHRKSPLLSEK
>Mature_135_residues
MRVIPIPARAGITGFESPAAEYTQLGLSLDELLINHPSSTFLAFAEGDSMQGKGIFDGDILIIDRHETARYGDVIVASLN
REFICKIIDIPRRLLLSSNPQHQPVIIHEYDEFSIEGVITRSIRCHRKSPLLSEK

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=115, Percent_Identity=39.1304347826087, Blast_Score=92, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 15100; Mature: 15100

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIPIPARAGITGFESPAAEYTQLGLSLDELLINHPSSTFLAFAEGDSMQGKGIFDGDI
CEEECCCCCCCCCCCCCCCHHHHHHCCCHHHHHHCCCCCEEEEEECCCCCCCCEEECCCE
LIIDRHETARYGDVIVASLNREFICKIIDIPRRLLLSSNPQHQPVIIHEYDEFSIEGVIT
EEEECCCCCCCCCEEEEECCHHHHHHHHHCCHHHHHCCCCCCCCEEEEECCCEEEEEEEE
RSIRCHRKSPLLSEK
ECEEECCCCCCCCCC
>Mature Secondary Structure
MRVIPIPARAGITGFESPAAEYTQLGLSLDELLINHPSSTFLAFAEGDSMQGKGIFDGDI
CEEECCCCCCCCCCCCCCCHHHHHHCCCHHHHHHCCCCCEEEEEECCCCCCCCEEECCCE
LIIDRHETARYGDVIVASLNREFICKIIDIPRRLLLSSNPQHQPVIIHEYDEFSIEGVIT
EEEECCCCCCCCCEEEEECCHHHHHHHHHCCHHHHHCCCCCCCCEEEEECCCEEEEEEEE
RSIRCHRKSPLLSEK
ECEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]