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The map label for this gene is dapB

Identifier: 126175506

GI number: 126175506

Start: 3872289

End: 3873101

Strand: Reverse

Name: dapB

Synonym: Sbal_3306

Alternate gene names: 126175506

Gene position: 3873101-3872289 (Counterclockwise)

Preceding gene: 126175507

Following gene: 126175505

Centisome position: 75.54

GC content: 50.06

Gene sequence:

>813_bases
ATGAGTGGACAAGTGAGAGTGGCAATCGTCGGTGCCGGTGGTCGTATGGGACGCACTCTTATTGAAGCGGCTTACAATCA
TGACCATATATTGCTGGGTGCCGCTATTGAGCGCGCTGGCTCTAGTTTAGTGGGCGTGGATGCAGGTGAGCTAGCTGGTG
TGGGTAAATTAAAAGTCATGATCATGGATTCGCTGGATTACGCGACCGATGATTTTGATGTCTTGATTGATTTCACTGCG
CCAGACGCCAGTATTGTCCATTTAGATTGGTGTGTGCGCCATAAGAAAGCCATGGTGATCGGCACAACCGGTTTCAATCA
TGCTCAAAAAGAACAGATCAATGCTTTTGCCGAGCAAACGCCGGTAGTGATGGCGCCGAATATGTCTGTGGGTGTCAACC
TGATGTGGAAATTGCTCGAACTGGCTGCCGAAGTCATGGGTGATTACACGGATATCGAAATTATCGAAGGTCACCACAGA
CACAAAAAAGATGCGCCATCGGGTACAGCCTTGAAAATGGGTGAAGTAATTGCTAAGACCTTAGGTCGCGATCTTGAGAA
ATGTGCCGTGTATGGCCGCGAGGGGATCACGGGTGAACGCGATCGTGAAACCATAGGTTTTGCGACTATTCGTGCCGGTG
ACTTAGTCGGTGAACATACGGCCATGTTTGCCGATATCGGTGAGCGTTTAGAGATCACCCATAAAGCCTCGAGCCGTATG
ACCTTTGCTAACGGCGCTATGCGCGCCGCCCACTGGCTCGTGGAGCAAAAGCCGGGCTTGTATGATATGCAGCAGGTTTT
AGGTTTGCATTAA

Upstream 100 bases:

>100_bases
TCGAAGTTGAATTATTAGATATCATCTAATATTGATAAAACGCCTAAGCCTGTCTTAGGCGTTTTCTTATGGAAGACAAA
GAAAGATTGAGGAGATTGAA

Downstream 100 bases:

>100_bases
TATTAAAAACGCCGATATGGCGTTTTTTTTTGCACCCAGATACCAATGGGTGGACGGTTTCGCGTTTTTCCTGTAAACTC
GCTGGAATTTGTCAAAATTT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSGQVRVAIVGAGGRMGRTLIEAAYNHDHILLGAAIERAGSSLVGVDAGELAGVGKLKVMIMDSLDYATDDFDVLIDFTA
PDASIVHLDWCVRHKKAMVIGTTGFNHAQKEQINAFAEQTPVVMAPNMSVGVNLMWKLLELAAEVMGDYTDIEIIEGHHR
HKKDAPSGTALKMGEVIAKTLGRDLEKCAVYGREGITGERDRETIGFATIRAGDLVGEHTAMFADIGERLEITHKASSRM
TFANGAMRAAHWLVEQKPGLYDMQQVLGLH

Sequences:

>Translated_270_residues
MSGQVRVAIVGAGGRMGRTLIEAAYNHDHILLGAAIERAGSSLVGVDAGELAGVGKLKVMIMDSLDYATDDFDVLIDFTA
PDASIVHLDWCVRHKKAMVIGTTGFNHAQKEQINAFAEQTPVVMAPNMSVGVNLMWKLLELAAEVMGDYTDIEIIEGHHR
HKKDAPSGTALKMGEVIAKTLGRDLEKCAVYGREGITGERDRETIGFATIRAGDLVGEHTAMFADIGERLEITHKASSRM
TFANGAMRAAHWLVEQKPGLYDMQQVLGLH
>Mature_269_residues
SGQVRVAIVGAGGRMGRTLIEAAYNHDHILLGAAIERAGSSLVGVDAGELAGVGKLKVMIMDSLDYATDDFDVLIDFTAP
DASIVHLDWCVRHKKAMVIGTTGFNHAQKEQINAFAEQTPVVMAPNMSVGVNLMWKLLELAAEVMGDYTDIEIIEGHHRH
KKDAPSGTALKMGEVIAKTLGRDLEKCAVYGREGITGERDRETIGFATIRAGDLVGEHTAMFADIGERLEITHKASSRMT
FANGAMRAAHWLVEQKPGLYDMQQVLGLH

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=267, Percent_Identity=66.6666666666667, Blast_Score=347, Evalue=7e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_SHEB2 (B8E4S9)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002356988.1
- ProteinModelPortal:   B8E4S9
- SMR:   B8E4S9
- GeneID:   7087823
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_1050
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29265; Mature: 29134

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQVRVAIVGAGGRMGRTLIEAAYNHDHILLGAAIERAGSSLVGVDAGELAGVGKLKVM
CCCCEEEEEEECCCHHHHHHHHHHCCCCEEEEEHHHHHCCCCEEECCCHHHCCCCEEEEE
IMDSLDYATDDFDVLIDFTAPDASIVHLDWCVRHKKAMVIGTTGFNHAQKEQINAFAEQT
EEECCCCCCCCEEEEEEECCCCCEEEEEHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCC
PVVMAPNMSVGVNLMWKLLELAAEVMGDYTDIEIIEGHHRHKKDAPSGTALKMGEVIAKT
CEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHH
LGRDLEKCAVYGREGITGERDRETIGFATIRAGDLVGEHTAMFADIGERLEITHKASSRM
HCCCHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCE
TFANGAMRAAHWLVEQKPGLYDMQQVLGLH
EECCCHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SGQVRVAIVGAGGRMGRTLIEAAYNHDHILLGAAIERAGSSLVGVDAGELAGVGKLKVM
CCCEEEEEEECCCHHHHHHHHHHCCCCEEEEEHHHHHCCCCEEECCCHHHCCCCEEEEE
IMDSLDYATDDFDVLIDFTAPDASIVHLDWCVRHKKAMVIGTTGFNHAQKEQINAFAEQT
EEECCCCCCCCEEEEEEECCCCCEEEEEHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCC
PVVMAPNMSVGVNLMWKLLELAAEVMGDYTDIEIIEGHHRHKKDAPSGTALKMGEVIAKT
CEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHH
LGRDLEKCAVYGREGITGERDRETIGFATIRAGDLVGEHTAMFADIGERLEITHKASSRM
HCCCHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCE
TFANGAMRAAHWLVEQKPGLYDMQQVLGLH
EECCCHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA