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The map label for this gene is ribB [H]

Identifier: 126175359

GI number: 126175359

Start: 3696908

End: 3698011

Strand: Reverse

Name: ribB [H]

Synonym: Sbal_3158

Alternate gene names: 126175359

Gene position: 3698011-3696908 (Counterclockwise)

Preceding gene: 126175360

Following gene: 126175358

Centisome position: 72.12

GC content: 50.09

Gene sequence:

>1104_bases
ATGGCGCTGCACAGTATAGAAGAGATCATCGAAGATATTCGTCAAGGCAAAATGGTTATTTTGATGGATGACGAAGACAG
AGAAAACGAAGGTGATTTGATCATGGCGGCCGAAATGGTAACGCCAGAAGCGATTAACTTTATGGCGAAATATGGCCGTG
GACTCATTTGCCAGACCATGACCAAAGCCCGTTGTCAGCAGTTAAATCTGCCCTTAATGGTGACGAATAACAACGCCCAG
TTCTCGACTAACTTTACGGTTTCTATTGAAGCAGCCGAAGGCGTGACTACCGGTATTTCGGCCCACGACCGCGCGGTAAC
GGTAAAAGCGGCCGTGGCTAAAGAGGCTAAAGCGTCTGATTTAGTGCAACCTGGGCATATCTTCCCGTTAATGGCACAGG
ACGGCGGCGTATTAACCCGCGCAGGCCACACTGAAGCTGGTTGTGATTTAGCCCGTCTTGCGGGACTTGAGCCATCGGGC
GTTATCGTTGAGATTTTGAACGAAGACGGCACTATGGCACGCCGCCCAGATTTAGAGATTTTCTCCGAGTTGCACGGTAT
CAAAATCGGCACTATCGCGGCATTGATCGAGTATCGCAACACTAAAGAAACCACGGTTGTGCGTGAAGCTAAATGCAAAC
TACCGACCCGTTTCGGCGAGTTCGATATGGTGACTTTCAGAGACACTATCGACAATCAACTGCATTTTGCCTTAGTCAAA
GGTGAGGTGAAGAGTGATTGTTTGGTGCGCGTGCATCTGCAAAACACCTTCAACGATTTACTCCATTCAGAGCGCGATCA
GCAACGCAGCTGGCCACTCGAAAAGGCGATGGAGCGTATTTCAGCAGAAGGTGGCGTATTGGTTTTACTAGGGAATCAAG
AACATCCCTGTGAAATCCTCTCTAAGGTGAAAGCCTTTGAAGCCGAAGATCAAGGCCAAGCGCCTGCTTCTGCAAAATGG
CAGGGAACGTCGCGCCGTGTGGGTGTGGGTTCGCAAATCCTCGCTAGCCTTGGCGTGACTAAGATGCGCCTGCTCAGCTC
GCCTAAACGTTACCATTCACTTTCGGGCTTTGGCCTTGAAGTGACTGAGTATGTGGCGGACTAA

Upstream 100 bases:

>100_bases
GGAAATGTTAGCCCGTGCCGGCTTTGTGCGTTAGTGCACTGGTAATCGTACTGCTAAGGTATAGAATTTCATAACAACAG
CAAAATCATAAGGTCCTACA

Downstream 100 bases:

>100_bases
AACCCAAAGTTACACTGAAGTAAAATTAACAATTTCTGATAATTTGCATAGGGCTCTGGGCAATTGGCTGTGATATCATG
TCGCCACTTTTCGCCCCGAG

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MALHSIEEIIEDIRQGKMVILMDDEDRENEGDLIMAAEMVTPEAINFMAKYGRGLICQTMTKARCQQLNLPLMVTNNNAQ
FSTNFTVSIEAAEGVTTGISAHDRAVTVKAAVAKEAKASDLVQPGHIFPLMAQDGGVLTRAGHTEAGCDLARLAGLEPSG
VIVEILNEDGTMARRPDLEIFSELHGIKIGTIAALIEYRNTKETTVVREAKCKLPTRFGEFDMVTFRDTIDNQLHFALVK
GEVKSDCLVRVHLQNTFNDLLHSERDQQRSWPLEKAMERISAEGGVLVLLGNQEHPCEILSKVKAFEAEDQGQAPASAKW
QGTSRRVGVGSQILASLGVTKMRLLSSPKRYHSLSGFGLEVTEYVAD

Sequences:

>Translated_367_residues
MALHSIEEIIEDIRQGKMVILMDDEDRENEGDLIMAAEMVTPEAINFMAKYGRGLICQTMTKARCQQLNLPLMVTNNNAQ
FSTNFTVSIEAAEGVTTGISAHDRAVTVKAAVAKEAKASDLVQPGHIFPLMAQDGGVLTRAGHTEAGCDLARLAGLEPSG
VIVEILNEDGTMARRPDLEIFSELHGIKIGTIAALIEYRNTKETTVVREAKCKLPTRFGEFDMVTFRDTIDNQLHFALVK
GEVKSDCLVRVHLQNTFNDLLHSERDQQRSWPLEKAMERISAEGGVLVLLGNQEHPCEILSKVKAFEAEDQGQAPASAKW
QGTSRRVGVGSQILASLGVTKMRLLSSPKRYHSLSGFGLEVTEYVAD
>Mature_366_residues
ALHSIEEIIEDIRQGKMVILMDDEDRENEGDLIMAAEMVTPEAINFMAKYGRGLICQTMTKARCQQLNLPLMVTNNNAQF
STNFTVSIEAAEGVTTGISAHDRAVTVKAAVAKEAKASDLVQPGHIFPLMAQDGGVLTRAGHTEAGCDLARLAGLEPSGV
IVEILNEDGTMARRPDLEIFSELHGIKIGTIAALIEYRNTKETTVVREAKCKLPTRFGEFDMVTFRDTIDNQLHFALVKG
EVKSDCLVRVHLQNTFNDLLHSERDQQRSWPLEKAMERISAEGGVLVLLGNQEHPCEILSKVKAFEAEDQGQAPASAKWQ
GTSRRVGVGSQILASLGVTKMRLLSSPKRYHSLSGFGLEVTEYVAD

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=198, Percent_Identity=52.5252525252525, Blast_Score=217, Evalue=7e-58,
Organism=Escherichia coli, GI1787533, Length=166, Percent_Identity=32.5301204819277, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=45.771144278607, Blast_Score=182, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40292; Mature: 40160

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALHSIEEIIEDIRQGKMVILMDDEDRENEGDLIMAAEMVTPEAINFMAKYGRGLICQTM
CCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEHHH
TKARCQQLNLPLMVTNNNAQFSTNFTVSIEAAEGVTTGISAHDRAVTVKAAVAKEAKASD
HHHHHHHCCCCEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHC
LVQPGHIFPLMAQDGGVLTRAGHTEAGCDLARLAGLEPSGVIVEILNEDGTMARRPDLEI
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCHHH
FSELHGIKIGTIAALIEYRNTKETTVVREAKCKLPTRFGEFDMVTFRDTIDNQLHFALVK
HHHHCCCCHHHHHHHHHHCCCCHHHEEHHHHCCCCCCCCCEEEEEECCCCCCCEEEEEEE
GEVKSDCLVRVHLQNTFNDLLHSERDQQRSWPLEKAMERISAEGGVLVLLGNQEHPCEIL
CCCCCCEEEEEEEHHHHHHHHHCHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCHHHHH
SKVKAFEAEDQGQAPASAKWQGTSRRVGVGSQILASLGVTKMRLLSSPKRYHSLSGFGLE
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCHHHHCCCCCCCC
VTEYVAD
HHHHHCC
>Mature Secondary Structure 
ALHSIEEIIEDIRQGKMVILMDDEDRENEGDLIMAAEMVTPEAINFMAKYGRGLICQTM
CHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEHHH
TKARCQQLNLPLMVTNNNAQFSTNFTVSIEAAEGVTTGISAHDRAVTVKAAVAKEAKASD
HHHHHHHCCCCEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHC
LVQPGHIFPLMAQDGGVLTRAGHTEAGCDLARLAGLEPSGVIVEILNEDGTMARRPDLEI
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCHHH
FSELHGIKIGTIAALIEYRNTKETTVVREAKCKLPTRFGEFDMVTFRDTIDNQLHFALVK
HHHHCCCCHHHHHHHHHHCCCCHHHEEHHHHCCCCCCCCCEEEEEECCCCCCCEEEEEEE
GEVKSDCLVRVHLQNTFNDLLHSERDQQRSWPLEKAMERISAEGGVLVLLGNQEHPCEIL
CCCCCCEEEEEEEHHHHHHHHHCHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCHHHHH
SKVKAFEAEDQGQAPASAKWQGTSRRVGVGSQILASLGVTKMRLLSSPKRYHSLSGFGLE
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCHHHHCCCCCCCC
VTEYVAD
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339274 [H]