Click here to switch to the map view.

The map label for this gene is ribH [H]

Identifier: 126175358

GI number: 126175358

Start: 3696298

End: 3696777

Strand: Reverse

Name: ribH [H]

Synonym: Sbal_3157

Alternate gene names: 126175358

Gene position: 3696777-3696298 (Counterclockwise)

Preceding gene: 126175359

Following gene: 126175357

Centisome position: 72.1

GC content: 45.0

Gene sequence:

>480_bases
ATGAACGTAGTTCAAGGTAATATCGAAGCGAAAAATGCCAAAGTTGCGATTGTAATTTCGCGTTTCAACAGCTTTTTAGT
TGAGAGCTTGCTTGAAGGTGCACTTGACACGCTGAAACGTTTTGGCCAAGTCAGCGACGACAATATCACTGTTGTCCGTG
TACCAGGTGCGGTTGAGTTGCCGCTAGCTGCGCGTCGCGTAGCTGCCAGTGGTAAATTCGACGGTATTATCGCATTAGGT
GCGGTGATCCGTGGTGGTACTCCTCATTTTGATTTTGTTGCAGGCGAATGTAATAAAGGTCTAGCTCAAGTTGCTTTAGA
ATTTGATCTGCCTGTTGCTTTCGGTGTTTTGACCACAGATACCATTGAACAAGCTATTGAACGTTCAGGTACCAAAGCGG
GTAACAAAGGCGGCGAAGCTGCTTTAAGTCTGCTTGAAATGGTCAATGTTCTGCAAGAACTTGAACAACAGTTGTTATAG

Upstream 100 bases:

>100_bases
AATTTCTGATAATTTGCATAGGGCTCTGGGCAATTGGCTGTGATATCATGTCGCCACTTTTCGCCCCGAGCTGGGTGCTT
TAGCTAAATTAGGTAAGATA

Downstream 100 bases:

>100_bases
TAGGAAAAATAATGAAGCCTTCTGAGCGCCGCAAGGCCCGCCGTTTAGCCGTTCAAGCCATCTATTCATGGCAACTAAGC
GGGAATAATATTGCCGATGT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MNVVQGNIEAKNAKVAIVISRFNSFLVESLLEGALDTLKRFGQVSDDNITVVRVPGAVELPLAARRVAASGKFDGIIALG
AVIRGGTPHFDFVAGECNKGLAQVALEFDLPVAFGVLTTDTIEQAIERSGTKAGNKGGEAALSLLEMVNVLQELEQQLL

Sequences:

>Translated_159_residues
MNVVQGNIEAKNAKVAIVISRFNSFLVESLLEGALDTLKRFGQVSDDNITVVRVPGAVELPLAARRVAASGKFDGIIALG
AVIRGGTPHFDFVAGECNKGLAQVALEFDLPVAFGVLTTDTIEQAIERSGTKAGNKGGEAALSLLEMVNVLQELEQQLL
>Mature_159_residues
MNVVQGNIEAKNAKVAIVISRFNSFLVESLLEGALDTLKRFGQVSDDNITVVRVPGAVELPLAARRVAASGKFDGIIALG
AVIRGGTPHFDFVAGECNKGLAQVALEFDLPVAFGVLTTDTIEQAIERSGTKAGNKGGEAALSLLEMVNVLQELEQQLL

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=155, Percent_Identity=63.8709677419355, Blast_Score=209, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6324429, Length=143, Percent_Identity=32.8671328671329, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16776; Mature: 16776

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVVQGNIEAKNAKVAIVISRFNSFLVESLLEGALDTLKRFGQVSDDNITVVRVPGAVEL
CCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEC
PLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECNKGLAQVALEFDLPVAFGVLTTD
CHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHCCCCHHHHHHHHH
TIEQAIERSGTKAGNKGGEAALSLLEMVNVLQELEQQLL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVVQGNIEAKNAKVAIVISRFNSFLVESLLEGALDTLKRFGQVSDDNITVVRVPGAVEL
CCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEC
PLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECNKGLAQVALEFDLPVAFGVLTTD
CHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHCCCCHHHHHHHHH
TIEQAIERSGTKAGNKGGEAALSLLEMVNVLQELEQQLL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA