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The map label for this gene is thiL [H]

Identifier: 126175356

GI number: 126175356

Start: 3694847

End: 3695818

Strand: Reverse

Name: thiL [H]

Synonym: Sbal_3155

Alternate gene names: 126175356

Gene position: 3695818-3694847 (Counterclockwise)

Preceding gene: 126175357

Following gene: 126175355

Centisome position: 72.08

GC content: 51.23

Gene sequence:

>972_bases
GTGCCAAACTGTACAGTGAAAGAATTCCAATTAATTGAATGTTATTTTAGCAACCGCGGCCCCACTCGCCGCGATGTGAA
GCTTGGCATCGGTGACGATTGCGCTTTAGTGCAACCCGCAGAAAATAAGTCGATTGCTATCTCCTGTGACACCTTAGTCG
AAAATGTCCATTTCTTCCCCGATATGCCTCCTGCTGCCTTAGGTTACAAAGCCTTAGCGGTAAATTTATCTGATCTGGCT
GCCATGGGCGCTGAACCCGCGTGGATGACGCTTGCCTTGACGCTACCCGAAGTCGATGAAACTTGGCTCAGTGGTTTTAG
CGAAGGTTTATTTGAAGCGGCCGATTACTATGGCATCGCCTTAATTGGTGGCGATACGACTCGTGGCCCACGGGCGATTA
ATATCACAGTGCACGGCCAAGTCCCACAGGGTAAGGCACTGACGCGTCATGGTGCTAAAGCCGGTGATTGGATTTATGTC
ACGGGCACGCTCGGAGATTCGGCCTTAGGTCTGGATATCATTCGCGGCGCGCAACAGGCTAGAGCCGAGCATAAAGAATT
CCTGATCAATCGCCATTATCGTCCAACACCAAGAGTCTTAGCGGGCCAAGCATTGCGTTCGCTTGCCTCCAGTGCTATCG
ACCTTTCCGACGGGTTTATCTCGGATATCGGTCATGTACTTAAGGCTTCGGCAGTTGGCGCGGTTGTAGATGTTAATTGC
ATCCCGCTTTCGCGCGCGATGCAAGATACCGTCAGCGAGGAGCATGCCTTAGGTTATGCACTGACAGGCGGCGAAGATTA
CGAATTGTTGTTCACCGTTCCTGAGGCGCAAAAAGGCGCGCTTGAGACGGCATTAAGCCATGCAGGAGCAAAGTTTGTTA
GTGTTGGGCAAATTTGTGCGGGCAGTAAGCTCAAGTTACAACTCAATGGTGAGCCGTTTACGCCGCCGTATCACGGTTTC
GAGCACTTTTAA

Upstream 100 bases:

>100_bases
GAACGGACTGCTCGACAAACTGGTTGCACGCAAGTAATAAAGACAAACGGTATCTTAGGATACCGTTTTTCATTGCTAAC
AAAGGTGGCCGATGTAAGTC

Downstream 100 bases:

>100_bases
GCGAAGAGCATGTTAATGAAATGGTTGTCAAAGGATCAGGCGTTAACGCGCCTGTCATTAAAAAATCCTGTCCACTTTTT
GGCACTCGGTTTCGGTAGCG

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MPNCTVKEFQLIECYFSNRGPTRRDVKLGIGDDCALVQPAENKSIAISCDTLVENVHFFPDMPPAALGYKALAVNLSDLA
AMGAEPAWMTLALTLPEVDETWLSGFSEGLFEAADYYGIALIGGDTTRGPRAINITVHGQVPQGKALTRHGAKAGDWIYV
TGTLGDSALGLDIIRGAQQARAEHKEFLINRHYRPTPRVLAGQALRSLASSAIDLSDGFISDIGHVLKASAVGAVVDVNC
IPLSRAMQDTVSEEHALGYALTGGEDYELLFTVPEAQKGALETALSHAGAKFVSVGQICAGSKLKLQLNGEPFTPPYHGF
EHF

Sequences:

>Translated_323_residues
MPNCTVKEFQLIECYFSNRGPTRRDVKLGIGDDCALVQPAENKSIAISCDTLVENVHFFPDMPPAALGYKALAVNLSDLA
AMGAEPAWMTLALTLPEVDETWLSGFSEGLFEAADYYGIALIGGDTTRGPRAINITVHGQVPQGKALTRHGAKAGDWIYV
TGTLGDSALGLDIIRGAQQARAEHKEFLINRHYRPTPRVLAGQALRSLASSAIDLSDGFISDIGHVLKASAVGAVVDVNC
IPLSRAMQDTVSEEHALGYALTGGEDYELLFTVPEAQKGALETALSHAGAKFVSVGQICAGSKLKLQLNGEPFTPPYHGF
EHF
>Mature_322_residues
PNCTVKEFQLIECYFSNRGPTRRDVKLGIGDDCALVQPAENKSIAISCDTLVENVHFFPDMPPAALGYKALAVNLSDLAA
MGAEPAWMTLALTLPEVDETWLSGFSEGLFEAADYYGIALIGGDTTRGPRAINITVHGQVPQGKALTRHGAKAGDWIYVT
GTLGDSALGLDIIRGAQQARAEHKEFLINRHYRPTPRVLAGQALRSLASSAIDLSDGFISDIGHVLKASAVGAVVDVNCI
PLSRAMQDTVSEEHALGYALTGGEDYELLFTVPEAQKGALETALSHAGAKFVSVGQICAGSKLKLQLNGEPFTPPYHGFE
HF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=318, Percent_Identity=58.4905660377358, Blast_Score=369, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34525; Mature: 34393

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNCTVKEFQLIECYFSNRGPTRRDVKLGIGDDCALVQPAENKSIAISCDTLVENVHFFP
CCCCCCHHEEEEEEEECCCCCCCCEEEECCCCCCEEECCCCCCEEEEEHHHHHHHHHCCC
DMPPAALGYKALAVNLSDLAAMGAEPAWMTLALTLPEVDETWLSGFSEGLFEAADYYGIA
CCCHHHHCCEEEEEEHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEE
LIGGDTTRGPRAINITVHGQVPQGKALTRHGAKAGDWIYVTGTLGDSALGLDIIRGAQQA
EECCCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
RAEHKEFLINRHYRPTPRVLAGQALRSLASSAIDLSDGFISDIGHVLKASAVGAVVDVNC
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEE
IPLSRAMQDTVSEEHALGYALTGGEDYELLFTVPEAQKGALETALSHAGAKFVSVGQICA
EEHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCHHEEHHHHCC
GSKLKLQLNGEPFTPPYHGFEHF
CCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
PNCTVKEFQLIECYFSNRGPTRRDVKLGIGDDCALVQPAENKSIAISCDTLVENVHFFP
CCCCCHHEEEEEEEECCCCCCCCEEEECCCCCCEEECCCCCCEEEEEHHHHHHHHHCCC
DMPPAALGYKALAVNLSDLAAMGAEPAWMTLALTLPEVDETWLSGFSEGLFEAADYYGIA
CCCHHHHCCEEEEEEHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEE
LIGGDTTRGPRAINITVHGQVPQGKALTRHGAKAGDWIYVTGTLGDSALGLDIIRGAQQA
EECCCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
RAEHKEFLINRHYRPTPRVLAGQALRSLASSAIDLSDGFISDIGHVLKASAVGAVVDVNC
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEE
IPLSRAMQDTVSEEHALGYALTGGEDYELLFTVPEAQKGALETALSHAGAKFVSVGQICA
EEHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCHHEEHHHHCC
GSKLKLQLNGEPFTPPYHGFEHF
CCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]