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The map label for this gene is xapR [H]

Identifier: 126175277

GI number: 126175277

Start: 3597488

End: 3598405

Strand: Direct

Name: xapR [H]

Synonym: Sbal_3076

Alternate gene names: 126175277

Gene position: 3597488-3598405 (Clockwise)

Preceding gene: 126175275

Following gene: 126175278

Centisome position: 70.16

GC content: 47.17

Gene sequence:

>918_bases
ATGAGCAAGATAAACGCACCAGAACTCGTCACCTTGAAGATGCTGCGGTATTTTCATCGGGTTGCGGAAGTAAAAAACTT
TACCGCTGCCGCCGAGCAACTGCATCTATCAAAATCTCCGCTGAGCGCACAAATCAAAGAGTTGGAATCGCTCCTTGGTG
TTGAGCTGTTCACTCGCAGCACTCGGCAAGTGGAGCTCACACCCTATGGCCAATTGTTAAGAGAAAAGTGCGAGCAAATA
TTCGAGCTGGTGAATACCTCATTGGAACAAGTGGCTCAGCTTGGGCGACTCGATAGAAACCATATTCGGATTGGCATCAT
GAGCTCGCTTTTTTGGATGGGATTTGGTGACATACTGAAAAGCTTTCGCAAGCAATGCCCTGATAATGAGCTGATCTTTC
AAGAGTTATCACCTGAAACTCAAAAAGTCGCCTTAGCGCATCAAGAAATCGATTTTGGCCTAGTGCGCTACGCCGACACC
TTAAATCTGCCGCACCTCATCGCCGAGACCATCACCAGCGAACCTATGGTGTTAGCGCTGGCAAATAAACATCCCTTAGC
CAGACGTAAAAGCATCGACTTGAGTGAACTCAAAGATGAGCCCTTTACCTTACTCAGCCGTGCCAACTCCGCTTCTAGCG
ATTTGATTATCGCCAGCTGTCAGGCCGCAGGATTTATGCCGCAACTGGTACAGGAAATGGTCGAGCCCAATAGCTTGATG
GCGATCATCGCTGGCGATAAAAGGGTATCCATAGTGCCGCAAAGTTATGCATCACAGCCTTGGCCTAGGGTAAAGTTTAT
TAAATTAAAACAAACTATTCCCGCCGATATCTGCCTGATTTATCGGCCAGAAATGGCTTCGCTGCCGATTATCGATAGCC
TTAGGGACTTATTGAAGCAACAAATCAAAACCATTTAG

Upstream 100 bases:

>100_bases
ACGACCCTCAGTATAAGCGGGCTTGGGGTTGCAAATAATCGCGATTAACCGCACTATTGCGCTGATAAAAAGGACAATAA
CTAAAAATAGTGAGCCTGAG

Downstream 100 bases:

>100_bases
ATTGTCTCCCAAACGAGTGCTATGCTGAGTTTAATATTCAGGGTTCATATTTTAAGGATATCAAGATGGATGAATTTTTA
GCGGCAGCCATTGAAGAAGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Xanthosine operon regulatory protein [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSKINAPELVTLKMLRYFHRVAEVKNFTAAAEQLHLSKSPLSAQIKELESLLGVELFTRSTRQVELTPYGQLLREKCEQI
FELVNTSLEQVAQLGRLDRNHIRIGIMSSLFWMGFGDILKSFRKQCPDNELIFQELSPETQKVALAHQEIDFGLVRYADT
LNLPHLIAETITSEPMVLALANKHPLARRKSIDLSELKDEPFTLLSRANSASSDLIIASCQAAGFMPQLVQEMVEPNSLM
AIIAGDKRVSIVPQSYASQPWPRVKFIKLKQTIPADICLIYRPEMASLPIIDSLRDLLKQQIKTI

Sequences:

>Translated_305_residues
MSKINAPELVTLKMLRYFHRVAEVKNFTAAAEQLHLSKSPLSAQIKELESLLGVELFTRSTRQVELTPYGQLLREKCEQI
FELVNTSLEQVAQLGRLDRNHIRIGIMSSLFWMGFGDILKSFRKQCPDNELIFQELSPETQKVALAHQEIDFGLVRYADT
LNLPHLIAETITSEPMVLALANKHPLARRKSIDLSELKDEPFTLLSRANSASSDLIIASCQAAGFMPQLVQEMVEPNSLM
AIIAGDKRVSIVPQSYASQPWPRVKFIKLKQTIPADICLIYRPEMASLPIIDSLRDLLKQQIKTI
>Mature_304_residues
SKINAPELVTLKMLRYFHRVAEVKNFTAAAEQLHLSKSPLSAQIKELESLLGVELFTRSTRQVELTPYGQLLREKCEQIF
ELVNTSLEQVAQLGRLDRNHIRIGIMSSLFWMGFGDILKSFRKQCPDNELIFQELSPETQKVALAHQEIDFGLVRYADTL
NLPHLIAETITSEPMVLALANKHPLARRKSIDLSELKDEPFTLLSRANSASSDLIIASCQAAGFMPQLVQEMVEPNSLMA
IIAGDKRVSIVPQSYASQPWPRVKFIKLKQTIPADICLIYRPEMASLPIIDSLRDLLKQQIKTI

Specific function: Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=270, Percent_Identity=32.5925925925926, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI157672245, Length=250, Percent_Identity=33.2, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787879, Length=250, Percent_Identity=31.6, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788748, Length=294, Percent_Identity=26.530612244898, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788887, Length=226, Percent_Identity=30.9734513274336, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790399, Length=280, Percent_Identity=24.2857142857143, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790262, Length=221, Percent_Identity=28.0542986425339, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081904, Length=195, Percent_Identity=25.6410256410256, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI145693105, Length=211, Percent_Identity=23.2227488151659, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34465; Mature: 34334

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKINAPELVTLKMLRYFHRVAEVKNFTAAAEQLHLSKSPLSAQIKELESLLGVELFTRS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
TRQVELTPYGQLLREKCEQIFELVNTSLEQVAQLGRLDRNHIRIGIMSSLFWMGFGDILK
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHH
SFRKQCPDNELIFQELSPETQKVALAHQEIDFGLVRYADTLNLPHLIAETITSEPMVLAL
HHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEE
ANKHPLARRKSIDLSELKDEPFTLLSRANSASSDLIIASCQAAGFMPQLVQEMVEPNSLM
CCCCCCHHHCCCCHHHHCCCHHHHHHHCCCCCCCEEEEECHHCCCHHHHHHHHHCCCCEE
AIIAGDKRVSIVPQSYASQPWPRVKFIKLKQTIPADICLIYRPEMASLPIIDSLRDLLKQ
EEEECCCEEEECCHHHCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
QIKTI
HHHCC
>Mature Secondary Structure 
SKINAPELVTLKMLRYFHRVAEVKNFTAAAEQLHLSKSPLSAQIKELESLLGVELFTRS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
TRQVELTPYGQLLREKCEQIFELVNTSLEQVAQLGRLDRNHIRIGIMSSLFWMGFGDILK
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHH
SFRKQCPDNELIFQELSPETQKVALAHQEIDFGLVRYADTLNLPHLIAETITSEPMVLAL
HHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEE
ANKHPLARRKSIDLSELKDEPFTLLSRANSASSDLIIASCQAAGFMPQLVQEMVEPNSLM
CCCCCCHHHCCCCHHHHCCCHHHHHHHCCCCCCCEEEEECHHCCCHHHHHHHHHCCCCEE
AIIAGDKRVSIVPQSYASQPWPRVKFIKLKQTIPADICLIYRPEMASLPIIDSLRDLLKQ
EEEECCCEEEECCHHHCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
QIKTI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2201776; 9205837; 9278503; 7559336 [H]