Click here to switch to the map view.

The map label for this gene is xseA [H]

Identifier: 126175187

GI number: 126175187

Start: 3510964

End: 3512310

Strand: Direct

Name: xseA [H]

Synonym: Sbal_2985

Alternate gene names: 126175187

Gene position: 3510964-3512310 (Clockwise)

Preceding gene: 126175183

Following gene: 126175196

Centisome position: 68.47

GC content: 50.26

Gene sequence:

>1347_bases
ATGCAAGGCACCAAAAACAATATTTATACTGTCTCGCGGCTCAATGGTGAAGTCAGACAAATTCTCGAGGGACAACTGGG
TAAAATTTGGCTCAATGGCGAAATATCCAACTTTTCCTCCCCCAGCTCAGGTCATTGGTATCTCACCTTAAAAGACCACT
CTTCCCAGATCCGTTGCGCCATGTTTAAAGGCCGTAATCAAACGGTCAGCTTTAAGCCCATCAATGGTCAGCAAGTGTTA
GTCAAAGGCGCGATCAGCGTGTATGAACCCAGAGGCGACTATCAATTATTAATTGAGTCCATGCTGCCTGCAGGGGATGG
ATTACTCGCCCAGCAGTTCGATGCACTCAAAATGAAACTCGCCGCCGAAGGATTATTCGCCGCGGACACCAAAAGACCAT
TGCCGAAAAATATCCAACGTATTGGCGTAATCACTTCGCCAACCGGCGCGGCAATTCGCGACGTCTTACACGTACTCGCA
AGGCGCGACCCTTCAATCGAAGTCATTATCTATCCGACTCAGGTTCAAGGCGAAACTGCAGCGCAGAGTATTTGTCAGGC
AATCAATATCGCCAACCAGCGTTTAGAGGTCGACGTATTACTGCTTACCCGCGGCGGCGGTTCGCTTGAGGATTTGTGGT
GTTTTAACAGCGAAGCCCTCGCCCACACAATTTATAACAGCGCCCTGCCCGTGGTCAGCGCCGTCGGCCACGAAGTCGAC
ACCACCATCAGTGATTACGTGGCTGATATTCGCGCCCCAACACCATCTGCAGGTGCCGAGTTGTTATCCCAAGATAGCGA
CAATAAGGCGCAAAAACTCGCAACAGCCTTATCGCGCTTGCAACAAAGTGCGAAACATTATCAACTTAAGCAAGAAAGAC
GACTCAGTTTGCTTGAGCACAGACTGCAGCGCCAAGATCCCAAACGGACCCTGCAACAGTTCGAGCAAAGATTCGATGAG
ATGCAATTAAGACTGGAGTCGGCGCTGTTGAATCGCTTGCACATACTCAGCCGCCGTCAGCAGTTACTCGCAAGTCGCCT
TGAACAGCAATCTCCCAAGCATAAGCTCACCATTGAGGGTAACCGCCTAAGTTATCTTGCGAGTCGCTTACAGGATGCAT
TACAGGACAAACTGAGCCAAAGTGAGCAACGGATAAAATACGCGGCCCATCAACTCGAAACCGTCAGTCCGCTTGCTACC
TTGAGCCGTGGTTACAGCATCACCACTGACATCCACAATCAAGTGGTCGACTCTGCCGATAAACTGACAATCGGTGATAG
CCTGCAAACCCGCTTACGCCATGGGCAAGTGATATCAACCGTCACTCAGATCAAGCCGCTCGAATAA

Upstream 100 bases:

>100_bases
AGTAGGATTTAGAGGTGAAATATTGCGGCGGGATTATACCTTGCATATCGGCACTGGTAAATGGAAAATAGCAAATATCC
CCATTTAATTGAGTAATTCG

Downstream 100 bases:

>100_bases
ATCTACATGACGCTGAAATAGTCTTAAAACACAAAAGGAACCCTAAGGTTCCTTTTGTTTCAAATGTGTCTGGTAAAAAA
CACTATTTGGTTTTTCTGTC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MQGTKNNIYTVSRLNGEVRQILEGQLGKIWLNGEISNFSSPSSGHWYLTLKDHSSQIRCAMFKGRNQTVSFKPINGQQVL
VKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFDALKMKLAAEGLFAADTKRPLPKNIQRIGVITSPTGAAIRDVLHVLA
RRDPSIEVIIYPTQVQGETAAQSICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
TTISDYVADIRAPTPSAGAELLSQDSDNKAQKLATALSRLQQSAKHYQLKQERRLSLLEHRLQRQDPKRTLQQFEQRFDE
MQLRLESALLNRLHILSRRQQLLASRLEQQSPKHKLTIEGNRLSYLASRLQDALQDKLSQSEQRIKYAAHQLETVSPLAT
LSRGYSITTDIHNQVVDSADKLTIGDSLQTRLRHGQVISTVTQIKPLE

Sequences:

>Translated_448_residues
MQGTKNNIYTVSRLNGEVRQILEGQLGKIWLNGEISNFSSPSSGHWYLTLKDHSSQIRCAMFKGRNQTVSFKPINGQQVL
VKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFDALKMKLAAEGLFAADTKRPLPKNIQRIGVITSPTGAAIRDVLHVLA
RRDPSIEVIIYPTQVQGETAAQSICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
TTISDYVADIRAPTPSAGAELLSQDSDNKAQKLATALSRLQQSAKHYQLKQERRLSLLEHRLQRQDPKRTLQQFEQRFDE
MQLRLESALLNRLHILSRRQQLLASRLEQQSPKHKLTIEGNRLSYLASRLQDALQDKLSQSEQRIKYAAHQLETVSPLAT
LSRGYSITTDIHNQVVDSADKLTIGDSLQTRLRHGQVISTVTQIKPLE
>Mature_448_residues
MQGTKNNIYTVSRLNGEVRQILEGQLGKIWLNGEISNFSSPSSGHWYLTLKDHSSQIRCAMFKGRNQTVSFKPINGQQVL
VKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFDALKMKLAAEGLFAADTKRPLPKNIQRIGVITSPTGAAIRDVLHVLA
RRDPSIEVIIYPTQVQGETAAQSICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
TTISDYVADIRAPTPSAGAELLSQDSDNKAQKLATALSRLQQSAKHYQLKQERRLSLLEHRLQRQDPKRTLQQFEQRFDE
MQLRLESALLNRLHILSRRQQLLASRLEQQSPKHKLTIEGNRLSYLASRLQDALQDKLSQSEQRIKYAAHQLETVSPLAT
LSRGYSITTDIHNQVVDSADKLTIGDSLQTRLRHGQVISTVTQIKPLE

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=441, Percent_Identity=49.6598639455782, Blast_Score=440, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 49976; Mature: 49976

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGTKNNIYTVSRLNGEVRQILEGQLGKIWLNGEISNFSSPSSGHWYLTLKDHSSQIRCA
CCCCCCCEEEEECCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEE
MFKGRNQTVSFKPINGQQVLVKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFDALKMKL
EECCCCCEEEEECCCCCEEEEEECHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAEGLFAADTKRPLPKNIQRIGVITSPTGAAIRDVLHVLARRDPSIEVIIYPTQVQGETA
HHCCCEECCCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
AQSICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
HHHHHHHHHHHCCEEEEEEEEEECCCCCCHHHEECCCHHHHHHHHHHHHHHHHHHCCHHH
TTISDYVADIRAPTPSAGAELLSQDSDNKAQKLATALSRLQQSAKHYQLKQERRLSLLEH
HHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQRQDPKRTLQQFEQRFDEMQLRLESALLNRLHILSRRQQLLASRLEQQSPKHKLTIEG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NRLSYLASRLQDALQDKLSQSEQRIKYAAHQLETVSPLATLSRGYSITTDIHNQVVDSAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCC
KLTIGDSLQTRLRHGQVISTVTQIKPLE
CEEECHHHHHHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure
MQGTKNNIYTVSRLNGEVRQILEGQLGKIWLNGEISNFSSPSSGHWYLTLKDHSSQIRCA
CCCCCCCEEEEECCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEE
MFKGRNQTVSFKPINGQQVLVKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFDALKMKL
EECCCCCEEEEECCCCCEEEEEECHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAEGLFAADTKRPLPKNIQRIGVITSPTGAAIRDVLHVLARRDPSIEVIIYPTQVQGETA
HHCCCEECCCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
AQSICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
HHHHHHHHHHHCCEEEEEEEEEECCCCCCHHHEECCCHHHHHHHHHHHHHHHHHHCCHHH
TTISDYVADIRAPTPSAGAELLSQDSDNKAQKLATALSRLQQSAKHYQLKQERRLSLLEH
HHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQRQDPKRTLQQFEQRFDEMQLRLESALLNRLHILSRRQQLLASRLEQQSPKHKLTIEG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NRLSYLASRLQDALQDKLSQSEQRIKYAAHQLETVSPLATLSRGYSITTDIHNQVVDSAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCC
KLTIGDSLQTRLRHGQVISTVTQIKPLE
CEEECHHHHHHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA