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The map label for this gene is cheA [H]

Identifier: 126175108

GI number: 126175108

Start: 3419861

End: 3422104

Strand: Reverse

Name: cheA [H]

Synonym: Sbal_2906

Alternate gene names: 126175108

Gene position: 3422104-3419861 (Counterclockwise)

Preceding gene: 126175109

Following gene: 126175107

Centisome position: 66.74

GC content: 46.66

Gene sequence:

>2244_bases
ATGGCCTTTGATGTAGATGAAGAGATACTCCAGGACTTTTTAATCGAAGCCGGTGAAATTTTAGAGCTTCTGCAAGAGCA
ACTCGTTGCGCTTGAAAATAATCCTGATGACACTAACTTGCTAAACGCCATTTTTCGAGGGTTCCATACCGTTAAAGGTG
GCGCAGGCTTTCTTAGCTTAACTCCCATGGTCGATGTGTGTCATGAGGCTGAAAATACCTTCGATCTATTGCGCACAGGC
AAACGCAGCGTAAACGCAGAGCTGATGGATATTATTTTGCAGGCTGTTGATGCAATTAATACCATGTTTGCTCAAACGCA
GCGGGGCGAACAACAAGATCCTGCTGAGTCAGGCCTGTTGGCTAGACTTAAAATGCTGAGTTCAGGTGCGCCATTGCCAT
CTGAAGTTGCGTCTGCAGAAGTGGTAGAAGTTGTCGAGCCAGAGCCTGTCGTTGAAGCCATTGTTGAAACTCCCGTCCCA
CAAGACATTCCCTCAGAGATAAGTAATAGCTCATCTTCAAGTATTGATGATATCAACGATGCTGAATTTGAAGCTTTGTT
AGATGCGCTTCATGGCTCTGGAAAAGGCCCAGCGGCTGCTACCGCTGTGGCGTCTGAACCTGTGGTCGCTAAGCCAGCAG
CGCCAGTTAAAGCGCCTTCAGCATCGGGTGATGACATCACTGATGATGAGTTTGAGGCATTGCTTGATGAACTGCATGGT
TCAGGCAGCAAGTTTAAAGCAGAGGAAGAAGTGCCAGCTAAACCAAAGGTCGCTTCGGCTCCCACGCCTCAACCGATAGT
GGATGCCGATGAAATTACTGATGATGAGTTTGAAAGATTACTCGATGAACTCCATGGTAAAAATGCGGCCCCTGCAAAAA
CGGAAGTAAAAGCGCCTACTGCATCAGTAACGCCAGCTTCGACTGCAGCACCTAAAGTTGCGACTCCCGTACCAGTTAAA
GCTGCCGCGCCTGCTCCAGTCCTTGTAGTTGCCGCAAAACCGAAAGTGGACATTGCGGTTGTTGAGAAAGCGCCAGCTAA
AGCAAGTTCAGCAAATGTGCCTCAAGGTGAAACTACAGTACGTGTTGATACTGCACGGCTCGACCAAATCATGAATATGG
TGGGCGAGTTAGTGTTAGTGCGTAATCGATTAGTGAGCTTAGGTATCAGTCGTGATGATGAGGAAATGTCTAAGGCCCTT
GCGAACTTAGATCTCGTGACTGCCGATTTGCAAGGCGCGGTGATGAAAACCCGTATGCAACCGATCAAGAAAGTGTTTGG
TCGTTTCCCTCGGGTAGTACGTGATCTTGCGCGTACACTCAATAAAGAAATTGATTTGATCATGGTCGGTGAAGAAACCG
ACCTAGATAAAAACTTAGTTGAAGCGCTTGCTGATCCACTCGTCCACTTAGTGCGTAACTCAGTGGATCACGGTATTGAA
ATGCCAAATGAGCGTGAAGCCAACGGCAAGCCGAGAACGGGTACGATTACCTTATCTGCAAGTCAGGAAGGTGACCATAT
ACTGCTGAAAATCGAAGACGATGGCGCAGGTATGGACCCTGAAAAACTGAAAAAGATCGCGATAACGCGTGGTGTGCTTG
ATGAAGATTCAGCTTCGCGAATGACTGACAGCGAAGCGTATAATTTGATTTTTGCGCCCGGTTTTTCGACTAAGGTCGAG
ATTTCAGATATTTCTGGTCGTGGCGTTGGGATGGACGTGGTAAAAACGCGTATCACTCAGCTTAACGGCACAGTGCATAT
TGATTCTATGAAAGGTAAGGGCACGATACTTGAGATTAAAGTACCGTTAACGCTGGCGATTATGCCAACCTTAATGGTTG
ATGTCGCTAAACAAGTGTTTGCATTACCTCTGTCTAGTGTGAACGAGATATTCCATCTCGATCTCACTAAGACCAATATC
GTCGATGGACAACTCACCGTCATAGTGCGTAACAAGGCTGTGCCTTTGTTCTATTTGGAGCACTGGCTGCATAGAAATAA
AACCACCTTTAAACATGGCGATAAAAAGCATGGTCATGTGGTGATTGTACAATTAGGTATGATGCAAATTGGTTTTGTTG
TGGATGCCCTAATAGGCCAAGAAGAGGTGGTGATTAAACCCCTTGGCGCTATGTTACACGGCACTCCTGGGATGGCTGGC
GCGACGATTACATCGGATGGTGGTATCGCACTGATCTTAGATGTCCCTGGATTGTTAAAGCATTATGCGAAAAGTAAGAA
TTAG

Upstream 100 bases:

>100_bases
GCCGATAATGAATGCCGAGCTTCGTCAAGATGTAGTAACGGGTCAAGACGAAGTGGATGATCTTCTATCGAGTCTGGGTT
TCTAACTGGGAGTCAATTTG

Downstream 100 bases:

>100_bases
TTTCCAAGCTAAGGAATGGAATGGCCATTAAAGTATTAGTCGTTGATGACTCAAGTTTTTTCAGACGACGTGTTAGTGAA
ATAGTCAATCAAGATCCTGA

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 747; Mature: 746

Protein sequence:

>747_residues
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSLTPMVDVCHEAENTFDLLRTG
KRSVNAELMDIILQAVDAINTMFAQTQRGEQQDPAESGLLARLKMLSSGAPLPSEVASAEVVEVVEPEPVVEAIVETPVP
QDIPSEISNSSSSSIDDINDAEFEALLDALHGSGKGPAAATAVASEPVVAKPAAPVKAPSASGDDITDDEFEALLDELHG
SGSKFKAEEEVPAKPKVASAPTPQPIVDADEITDDEFERLLDELHGKNAAPAKTEVKAPTASVTPASTAAPKVATPVPVK
AAAPAPVLVVAAKPKVDIAVVEKAPAKASSANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLVSLGISRDDEEMSKAL
ANLDLVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLIMVGEETDLDKNLVEALADPLVHLVRNSVDHGIE
MPNEREANGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKKIAITRGVLDEDSASRMTDSEAYNLIFAPGFSTKVE
ISDISGRGVGMDVVKTRITQLNGTVHIDSMKGKGTILEIKVPLTLAIMPTLMVDVAKQVFALPLSSVNEIFHLDLTKTNI
VDGQLTVIVRNKAVPLFYLEHWLHRNKTTFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAG
ATITSDGGIALILDVPGLLKHYAKSKN

Sequences:

>Translated_747_residues
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSLTPMVDVCHEAENTFDLLRTG
KRSVNAELMDIILQAVDAINTMFAQTQRGEQQDPAESGLLARLKMLSSGAPLPSEVASAEVVEVVEPEPVVEAIVETPVP
QDIPSEISNSSSSSIDDINDAEFEALLDALHGSGKGPAAATAVASEPVVAKPAAPVKAPSASGDDITDDEFEALLDELHG
SGSKFKAEEEVPAKPKVASAPTPQPIVDADEITDDEFERLLDELHGKNAAPAKTEVKAPTASVTPASTAAPKVATPVPVK
AAAPAPVLVVAAKPKVDIAVVEKAPAKASSANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLVSLGISRDDEEMSKAL
ANLDLVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLIMVGEETDLDKNLVEALADPLVHLVRNSVDHGIE
MPNEREANGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKKIAITRGVLDEDSASRMTDSEAYNLIFAPGFSTKVE
ISDISGRGVGMDVVKTRITQLNGTVHIDSMKGKGTILEIKVPLTLAIMPTLMVDVAKQVFALPLSSVNEIFHLDLTKTNI
VDGQLTVIVRNKAVPLFYLEHWLHRNKTTFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAG
ATITSDGGIALILDVPGLLKHYAKSKN
>Mature_746_residues
AFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSLTPMVDVCHEAENTFDLLRTGK
RSVNAELMDIILQAVDAINTMFAQTQRGEQQDPAESGLLARLKMLSSGAPLPSEVASAEVVEVVEPEPVVEAIVETPVPQ
DIPSEISNSSSSSIDDINDAEFEALLDALHGSGKGPAAATAVASEPVVAKPAAPVKAPSASGDDITDDEFEALLDELHGS
GSKFKAEEEVPAKPKVASAPTPQPIVDADEITDDEFERLLDELHGKNAAPAKTEVKAPTASVTPASTAAPKVATPVPVKA
AAPAPVLVVAAKPKVDIAVVEKAPAKASSANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLVSLGISRDDEEMSKALA
NLDLVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLIMVGEETDLDKNLVEALADPLVHLVRNSVDHGIEM
PNEREANGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKKIAITRGVLDEDSASRMTDSEAYNLIFAPGFSTKVEI
SDISGRGVGMDVVKTRITQLNGTVHIDSMKGKGTILEIKVPLTLAIMPTLMVDVAKQVFALPLSSVNEIFHLDLTKTNIV
DGQLTVIVRNKAVPLFYLEHWLHRNKTTFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAGA
TITSDGGIALILDVPGLLKHYAKSKN

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=435, Percent_Identity=40.4597701149425, Blast_Score=293, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79866; Mature: 79735

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSL
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEH
TPMVDVCHEAENTFDLLRTGKRSVNAELMDIILQAVDAINTMFAQTQRGEQQDPAESGLL
HHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ARLKMLSSGAPLPSEVASAEVVEVVEPEPVVEAIVETPVPQDIPSEISNSSSSSIDDIND
HHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCH
AEFEALLDALHGSGKGPAAATAVASEPVVAKPAAPVKAPSASGDDITDDEFEALLDELHG
HHHHHHHHHHHCCCCCCCHHHHHCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
SGSKFKAEEEVPAKPKVASAPTPQPIVDADEITDDEFERLLDELHGKNAAPAKTEVKAPT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
ASVTPASTAAPKVATPVPVKAAAPAPVLVVAAKPKVDIAVVEKAPAKASSANVPQGETTV
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEE
RVDTARLDQIMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTADLQGAVMKTRMQ
EEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHH
PIKKVFGRFPRVVRDLARTLNKEIDLIMVGEETDLDKNLVEALADPLVHLVRNSVDHGIE
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
MPNEREANGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKKIAITRGVLDEDSASR
CCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHH
MTDSEAYNLIFAPGFSTKVEISDISGRGVGMDVVKTRITQLNGTVHIDSMKGKGTILEIK
CCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEE
VPLTLAIMPTLMVDVAKQVFALPLSSVNEIFHLDLTKTNIVDGQLTVIVRNKAVPLFYLE
CCCHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEECCCCEEECCEEEEEEECCCCHHHHHH
HWLHRNKTTFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAG
HHHHCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCCC
ATITSDGGIALILDVPGLLKHYAKSKN
CEEECCCCEEEEEECCHHHHHHHCCCC
>Mature Secondary Structure 
AFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSL
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEH
TPMVDVCHEAENTFDLLRTGKRSVNAELMDIILQAVDAINTMFAQTQRGEQQDPAESGLL
HHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ARLKMLSSGAPLPSEVASAEVVEVVEPEPVVEAIVETPVPQDIPSEISNSSSSSIDDIND
HHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCH
AEFEALLDALHGSGKGPAAATAVASEPVVAKPAAPVKAPSASGDDITDDEFEALLDELHG
HHHHHHHHHHHCCCCCCCHHHHHCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
SGSKFKAEEEVPAKPKVASAPTPQPIVDADEITDDEFERLLDELHGKNAAPAKTEVKAPT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
ASVTPASTAAPKVATPVPVKAAAPAPVLVVAAKPKVDIAVVEKAPAKASSANVPQGETTV
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEE
RVDTARLDQIMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTADLQGAVMKTRMQ
EEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHH
PIKKVFGRFPRVVRDLARTLNKEIDLIMVGEETDLDKNLVEALADPLVHLVRNSVDHGIE
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
MPNEREANGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKKIAITRGVLDEDSASR
CCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHH
MTDSEAYNLIFAPGFSTKVEISDISGRGVGMDVVKTRITQLNGTVHIDSMKGKGTILEIK
CCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEE
VPLTLAIMPTLMVDVAKQVFALPLSSVNEIFHLDLTKTNIVDGQLTVIVRNKAVPLFYLE
CCCHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEECCCCEEECCEEEEEEECCCCHHHHHH
HWLHRNKTTFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAG
HHHHCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCCC
ATITSDGGIALILDVPGLLKHYAKSKN
CEEECCCCEEEEEECCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]