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The map label for this gene is rfbC [H]

Identifier: 126175069

GI number: 126175069

Start: 3374897

End: 3375436

Strand: Reverse

Name: rfbC [H]

Synonym: Sbal_2865

Alternate gene names: 126175069

Gene position: 3375436-3374897 (Counterclockwise)

Preceding gene: 126175070

Following gene: 126175068

Centisome position: 65.83

GC content: 48.15

Gene sequence:

>540_bases
ATGAAATGTAGCGAAACTGAGTTAGCCGAAGTGTTGGTGTTTGAACCGCAAGTCTTTGGGGATGAACGCGGTTTCTTTAT
GGAGACGTTTAGGCAATCCTATTTTGATGCCTGCTTTGCACAGCGTGGATTCGAGTCATGTGTGTTCGTGCAGGAGAATC
ACAGCCGTTCGCAACGTAATGTCCTGCGAGGCTTGCATTTTCAACGGCGTAAACCGCAGGGGAAGTTAGTGCGAGTCTGT
GCAGGGAGCATTTTTGATGTGGCCGTCGATATAAGGCCCGACTCTGCCACCTATGGGAAGTGGGTTGGGCGCGTGCTATC
AGCAGAGAATCATCTGCAAATGTGGATCCCACCGGGCTTTGCTCACGGTTTTTATGTTCTCAGTGATTATGCTGAGGTTA
TTTATCAATGTACCCAATATTATGATCCTGAAGATGAAGGCGTTGTCGCTTGGAATAGTGCAGAATTTGCCATTGATTGG
CCATTAATTGCCGCACCGATTTTATCCGCGCGAGATAGCCTCGCCAGTGCATCATCATAA

Upstream 100 bases:

>100_bases
GGTTGGATCAATGCGCAGCAATTAGTTGAATTAGCTCAGCCTTTACTCAAAAGTGGTTATGGTGAGTATTTGCTCGGCTT
ACTCGATAAGCAGGTATTTG

Downstream 100 bases:

>100_bases
AGCCAATCACGGTTTGTATTAAAAGGAATGACAATGAGTTTATTATTTTCGCCTTTAACCTTAGGTCAACTTGAGTTAGC
GAACCGCATTATTATCGCGC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKCSETELAEVLVFEPQVFGDERGFFMETFRQSYFDACFAQRGFESCVFVQENHSRSQRNVLRGLHFQRRKPQGKLVRVC
AGSIFDVAVDIRPDSATYGKWVGRVLSAENHLQMWIPPGFAHGFYVLSDYAEVIYQCTQYYDPEDEGVVAWNSAEFAIDW
PLIAAPILSARDSLASASS

Sequences:

>Translated_179_residues
MKCSETELAEVLVFEPQVFGDERGFFMETFRQSYFDACFAQRGFESCVFVQENHSRSQRNVLRGLHFQRRKPQGKLVRVC
AGSIFDVAVDIRPDSATYGKWVGRVLSAENHLQMWIPPGFAHGFYVLSDYAEVIYQCTQYYDPEDEGVVAWNSAEFAIDW
PLIAAPILSARDSLASASS
>Mature_179_residues
MKCSETELAEVLVFEPQVFGDERGFFMETFRQSYFDACFAQRGFESCVFVQENHSRSQRNVLRGLHFQRRKPQGKLVRVC
AGSIFDVAVDIRPDSATYGKWVGRVLSAENHLQMWIPPGFAHGFYVLSDYAEVIYQCTQYYDPEDEGVVAWNSAEFAIDW
PLIAAPILSARDSLASASS

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=173, Percent_Identity=55.4913294797688, Blast_Score=196, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17550412, Length=169, Percent_Identity=45.5621301775148, Blast_Score=137, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20324; Mature: 20324

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCSETELAEVLVFEPQVFGDERGFFMETFRQSYFDACFAQRGFESCVFVQENHSRSQRN
CCCCHHHHHHHHEECCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHH
VLRGLHFQRRKPQGKLVRVCAGSIFDVAVDIRPDSATYGKWVGRVLSAENHLQMWIPPGF
HHHHHHHHCCCCCCCCHHHHHCCEEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCC
AHGFYVLSDYAEVIYQCTQYYDPEDEGVVAWNSAEFAIDWPLIAAPILSARDSLASASS
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKCSETELAEVLVFEPQVFGDERGFFMETFRQSYFDACFAQRGFESCVFVQENHSRSQRN
CCCCHHHHHHHHEECCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHH
VLRGLHFQRRKPQGKLVRVCAGSIFDVAVDIRPDSATYGKWVGRVLSAENHLQMWIPPGF
HHHHHHHHCCCCCCCCHHHHHCCEEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCC
AHGFYVLSDYAEVIYQCTQYYDPEDEGVVAWNSAEFAIDWPLIAAPILSARDSLASASS
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7961452; 8655518 [H]