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The map label for this gene is nadA [H]

Identifier: 126174435

GI number: 126174435

Start: 2566811

End: 2567878

Strand: Reverse

Name: nadA [H]

Synonym: Sbal_2219

Alternate gene names: 126174435

Gene position: 2567878-2566811 (Counterclockwise)

Preceding gene: 126174436

Following gene: 126174432

Centisome position: 50.08

GC content: 50.47

Gene sequence:

>1068_bases
ATGAGTCAGTTTGCCCCCAGCATAGAAACCATTGATTACCCGTTTCCGCCTAAGCCAGTTCCTTTGTCCGATGCGCAAAA
AGCCGATTACAAGGCGCGTATCAAACAACTGCTCATTGAAAAAGATGCCGTTCTGGTTGCCCACTATTATACCGATCCTG
AAATCCAAGCCCTTGCCGAAGAAACCGGCGGCTGCGTTTCAGACTCCTTAGAAATGGCGCGCTTTGGCCGCGATCACCCA
GCAAAAACCTTAATCGTTGCTGGGGTCAAGTTTATGGGCGAAACCGCCAAGATTTTGAGCCCAGAAAAAACCATTTTAAT
GCCGACCTTAGAAGCCACTTGTTCATTGGACTTAGGTTGTCCAATCGATAAGTTCAGTGCTTTTTGCGATGCGCACCCAG
ATCATACTGTGGTGGTTTACGCCAATACTTCGGCTGCCGTTAAAGCGCGCGCCGACTGGGTGGTGACCTCTAGTATTGCC
CTCGAAATCGTTGAGCACTTAGACAGCGAAGGTAAAAAGATCATTTGGGGTCCAGACCGTCATTTGGGCAGCTATATTGC
TAAACAGACGGGCGCCGAAATGTTGATGTGGCAGGGCGATTGTATCGTTCACGACGAGTTTAAATCGAACGCGCTGCGCG
ATATGAAAAGCGTTTACCCAGATGCGGCTATCCTTGTGCACCCTGAGTCGCCAGCCAGTGTGGTGGCGATGGCTGATGCC
GTTGGCTCGACCAGTCAGCTGATCAAAGCGGCGCAGACAATGCCGAATGAGCGTTTTATCGTGGCAACCGATCGCGGTAT
CTTCTATAAAATGCAGCAGGCGGCGCCAGGTAAAATCTTAATCGAAGCGCCAACCGGCGGTAACGGTGCAACCTGTAAGA
GCTGTGCCCACTGTCCTTGGATGGCGATGAACGGTCTACAGGCCATTGAAGCGTCACTCGCCGACAGCGATAAAACCACC
CATGAGATTTTTGTGGATGAAGACTTAAGAGTTAAAGCGCTGATCCCGCTGACGCGCATGTTGGATTTTGCTAAGACACT
GAATATGAAAGTGAAGGGTAATGCCTAA

Upstream 100 bases:

>100_bases
GCTTTAGAGCGTCCTTTTTTATTTGCTTTGCACAAATGGGTTAATCTTTTGATCCCGATTACGTATAATTCCCGGACGTA
GTTATCCTGATGGATGTGTT

Downstream 100 bases:

>100_bases
ACATGGCTAAGTCCCTTCTTTAGCTGTTCTCCAGTGTCATAAAAATCCCCGCCATAGAGTGGGGATTTTTATGGCTGAAA
TTTAAGGTAATAAAAAGCCC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSQFAPSIETIDYPFPPKPVPLSDAQKADYKARIKQLLIEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHP
AKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPIDKFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIA
LEIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLMWQGDCIVHDEFKSNALRDMKSVYPDAAILVHPESPASVVAMADA
VGSTSQLIKAAQTMPNERFIVATDRGIFYKMQQAAPGKILIEAPTGGNGATCKSCAHCPWMAMNGLQAIEASLADSDKTT
HEIFVDEDLRVKALIPLTRMLDFAKTLNMKVKGNA

Sequences:

>Translated_355_residues
MSQFAPSIETIDYPFPPKPVPLSDAQKADYKARIKQLLIEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHP
AKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPIDKFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIA
LEIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLMWQGDCIVHDEFKSNALRDMKSVYPDAAILVHPESPASVVAMADA
VGSTSQLIKAAQTMPNERFIVATDRGIFYKMQQAAPGKILIEAPTGGNGATCKSCAHCPWMAMNGLQAIEASLADSDKTT
HEIFVDEDLRVKALIPLTRMLDFAKTLNMKVKGNA
>Mature_354_residues
SQFAPSIETIDYPFPPKPVPLSDAQKADYKARIKQLLIEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHPA
KTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPIDKFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAL
EIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLMWQGDCIVHDEFKSNALRDMKSVYPDAAILVHPESPASVVAMADAV
GSTSQLIKAAQTMPNERFIVATDRGIFYKMQQAAPGKILIEAPTGGNGATCKSCAHCPWMAMNGLQAIEASLADSDKTTH
EIFVDEDLRVKALIPLTRMLDFAKTLNMKVKGNA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=340, Percent_Identity=73.5294117647059, Blast_Score=537, Evalue=1e-154,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38567; Mature: 38436

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFAPSIETIDYPFPPKPVPLSDAQKADYKARIKQLLIEKDAVLVAHYYTDPEIQALAE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHH
ETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGC
HHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHCCCCCEEEEEECHHHEEECCCC
PIDKFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKKIIWGPDR
CHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHHHHCCCCCEEEECCCH
HLGSYIAKQTGAEMLMWQGDCIVHDEFKSNALRDMKSVYPDAAILVHPESPASVVAMADA
HHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHH
VGSTSQLIKAAQTMPNERFIVATDRGIFYKMQQAAPGKILIEAPTGGNGATCKSCAHCPW
CCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCHHHCCCCH
MAMNGLQAIEASLADSDKTTHEIFVDEDLRVKALIPLTRMLDFAKTLNMKVKGNA
HHHCCHHHHHHHHCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHCCEEEECCC
>Mature Secondary Structure 
SQFAPSIETIDYPFPPKPVPLSDAQKADYKARIKQLLIEKDAVLVAHYYTDPEIQALAE
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHH
ETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGC
HHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHCCCCCEEEEEECHHHEEECCCC
PIDKFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKKIIWGPDR
CHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHHHHCCCCCEEEECCCH
HLGSYIAKQTGAEMLMWQGDCIVHDEFKSNALRDMKSVYPDAAILVHPESPASVVAMADA
HHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHH
VGSTSQLIKAAQTMPNERFIVATDRGIFYKMQQAAPGKILIEAPTGGNGATCKSCAHCPW
CCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCHHHCCCCH
MAMNGLQAIEASLADSDKTTHEIFVDEDLRVKALIPLTRMLDFAKTLNMKVKGNA
HHHCCHHHHHHHHCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]