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The map label for this gene is sseB [H]

Identifier: 126174174

GI number: 126174174

Start: 2265819

End: 2266619

Strand: Direct

Name: sseB [H]

Synonym: Sbal_1950

Alternate gene names: 126174174

Gene position: 2265819-2266619 (Clockwise)

Preceding gene: 126174173

Following gene: 126174175

Centisome position: 44.19

GC content: 48.19

Gene sequence:

>801_bases
GTGGAAATTACAAATGTAGCAACTCAAGGTACCAGCATTACCAACAGTCAAGCGTCGGATGAGGTGAAAGCTCAGATAGC
GTCTCGCGGAGATTCAGCGCTCTCTGGTGGTATAGCCGTACTGTATATGTTTATGAATTTGCTGTCAGAACTAGCCGATG
CCAAATATGGCCAAATGCAGCAAAAGGCTGATGTGTCGCGCCAAGCCCAAGAGATGGCGAATCGGGTCGATGAGGCGATA
GCCCAAGTCTCGAAGCAAGGTGATAAAGCCACGGCAAATCTGCCAGCCGATGTCGTTAAGTATATGAGTGACAATGGCTT
TGAAGTTGATGGAATGAGCATCTGCGCTTATCTCGACCACAATGATCCCTCCGCTGTTTATATGAAAGAGTTACTCGACA
AAATTGCCGCTGCTGGACCAGCAGGAATGCAATCGGCGAGTTGGCAAGATGTGGTTAGTTATATGGATGAACACGGGATC
AAGGTCGATGGTCAGCGTTGTTGTGATTTTATCTGGGGTCTTCCCGAAGTCGGACGGCAATCGTGGCAAAACATCAGTAA
GGCGCATATGCAACAGATTGCCGATGCCCTTGGCGCTGCAGGAGGACTAGATAAAGGCAAGTTGCAAGCGGTGAAATCGG
CTTTGGAATCGGTCTCAAATCGCGCCTCTGACTTTGTTTCCCAGTCACAACTGCAACTGCAAAAAATGATGCAGACCTAT
AACGTGACCGTCAGTTTACTCAATAGCATGCAGACCATGTTGGCCGAGATGAATAAATCTATCGCCCAAAATGTCCGCTA
A

Upstream 100 bases:

>100_bases
TTAAACAGTATGCAAACCATGCTGGCGGAAATGAACAAGTCGATTGCGCAAAACATTCGTTAATTTAACGCGTTATCGTT
TCTTGTTGGAGGTCATCATT

Downstream 100 bases:

>100_bases
GGAGTCAGTAATGAAACAGCAAGAATTTGAAGTCCTTGAACATTTTCTGCAACGGGGCGGCTCACTGCGTATGTTGGCTG
ATGTCGAGCAAAGTGACTTG

Product: EspA family secreted protein

Products: NA

Alternate protein names: Secretion system effector B [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MEITNVATQGTSITNSQASDEVKAQIASRGDSALSGGIAVLYMFMNLLSELADAKYGQMQQKADVSRQAQEMANRVDEAI
AQVSKQGDKATANLPADVVKYMSDNGFEVDGMSICAYLDHNDPSAVYMKELLDKIAAAGPAGMQSASWQDVVSYMDEHGI
KVDGQRCCDFIWGLPEVGRQSWQNISKAHMQQIADALGAAGGLDKGKLQAVKSALESVSNRASDFVSQSQLQLQKMMQTY
NVTVSLLNSMQTMLAEMNKSIAQNVR

Sequences:

>Translated_266_residues
MEITNVATQGTSITNSQASDEVKAQIASRGDSALSGGIAVLYMFMNLLSELADAKYGQMQQKADVSRQAQEMANRVDEAI
AQVSKQGDKATANLPADVVKYMSDNGFEVDGMSICAYLDHNDPSAVYMKELLDKIAAAGPAGMQSASWQDVVSYMDEHGI
KVDGQRCCDFIWGLPEVGRQSWQNISKAHMQQIADALGAAGGLDKGKLQAVKSALESVSNRASDFVSQSQLQLQKMMQTY
NVTVSLLNSMQTMLAEMNKSIAQNVR
>Mature_266_residues
MEITNVATQGTSITNSQASDEVKAQIASRGDSALSGGIAVLYMFMNLLSELADAKYGQMQQKADVSRQAQEMANRVDEAI
AQVSKQGDKATANLPADVVKYMSDNGFEVDGMSICAYLDHNDPSAVYMKELLDKIAAAGPAGMQSASWQDVVSYMDEHGI
KVDGQRCCDFIWGLPEVGRQSWQNISKAHMQQIADALGAAGGLDKGKLQAVKSALESVSNRASDFVSQSQLQLQKMMQTY
NVTVSLLNSMQTMLAEMNKSIAQNVR

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. May act as a translocator that mediates translocation of SPI-2 TTSS effector proteins from intraphagosomal bacterial cells into the host cells. SseB i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Cell surface. Note=Secreted via type III secretion system 2 (SPI-2 TTSS). After secretion, localizes mainly on the surface of the bacterial cell [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the espA/sseB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005095 [H]

Pfam domain/function: PF03433 EspA [H]

EC number: NA

Molecular weight: Translated: 28762; Mature: 28762

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9786193; 9786194; 11677609 [H]