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The map label for this gene is asnC

Identifier: 126174140

GI number: 126174140

Start: 2223939

End: 2225339

Strand: Reverse

Name: asnC

Synonym: Sbal_1914

Alternate gene names: 126174140

Gene position: 2225339-2223939 (Counterclockwise)

Preceding gene: 126174142

Following gene: 126174129

Centisome position: 43.4

GC content: 48.39

Gene sequence:

>1401_bases
ATGAGCATCGCATCTGTCGCATCTGTATTTAAAGGTGAGCACGCCGTCGGTTCTAAAGTCACAGTTCGTGGCTGGGTCAG
AACCCGTCGTGACTCTAAAGCCGGCATCTCTTTTTTAGCTGTTTATGACGGCTCTTGCTTTAATCCTATCCAAGGTGTCG
TGCCCAATAGCTTAGATAATTACGACAACGAAGTGTTAAAGCTGACTGCGGGTTGTTCTGTTGTGATGACAGGCGACGTG
GTGGAGTCTCCAGGCGCAGGTCAAGCATTTGAACTGCAAGTGACTGATATTGAAGTCGCGGGCTGGGTTGATGATCCAGA
CACTTACCCAATGGCCGCTAAACGTCACTCAATTGAACATTTACGTGAATTAGCGCACTTACGCCCACGCACTAACATTA
TTGGTGCCGTTGCCCGCGTGCGTAACTGTTTATCCCAAGCGATTCACCGCTTCTACCACGAAGAAGGCTTTATTTGGGTA
TCGACCCCACTTATCACCGCCTCTGACTGTGAAGGCGCCGGTGAAATGTTCCGCGTATCGACCTTAGATATGGAAAACCT
GCCACGTACTGATGCAGGGAAAGTCGATTACGATAAAGATTTCTTCGGTAAAGAAGCTTTCCTAACCGTATCTGGCCAGT
TGAACGCTGAAACATACGCCTGTGCACTGTCAAAAGTGTATACCTTTGGCCCAACTTTCCGTGCTGAAAACTCAAACACC
AGCCGCCACTTAGCGGAATTTTGGATGGTTGAGCCTGAAGTGGCCTTCGCTAACTTAAACGACATCGCTGGCCTTGCCGA
AGCTATGTTGAAATACGCATTCAATGCCGTATTGACTGAGCGTATGGACGATTTAACTTTCTTCGCCCAGCACGTTGATA
AGACAGTGATCGACCGTCTGCAATCTTTCGTTTCAAGTGATTTTGCTCAAGTGGATTACACAGATGCGGTTGAAATTCTG
CAAAACTGTGGCAGAACCTTCGAGTTCCCAGTGTCTTGGGGTATCGACTTATCTTCTGAGCATGAGCGTTACTTAGCCGA
AGAACACTTCAAAGCCCCTGTGGTTGTGAAGAACTATCCAAAAGATATCAAAGCCTTCTACATGCGCTTAAACGATGACG
GTAAAACCGTTGCCGCGATGGACGTGTTAGCCCCAGGTATCGGTGAAATCATCGGTGGGTCTCAACGTGAAGAGCGTTTA
GACGTGCTGGATATGCGTTTAGCCGAAATGGATCTGAACCAAGAAGATTACTGGTGGTACCGTGATATGCGCCGTTATGG
CACAGTGCCACACGCCGGTTTTGGTCTAGGGTTTGAGCGTTTAGTGTCTTACGTGACGGGCGTTAACAACATTCGTGATG
TTATCCCGTTCCCACGTGCACCGCGCACTGCGAACTTCTAA

Upstream 100 bases:

>100_bases
AACCTCAGGATACCTTTTCAGCTTGAGAAAAGCCACCAGTAAGGTAATATAAACCTCCAAAATTTTCATATAAAACGTTT
CGTTGGAGAATTAAGCAACA

Downstream 100 bases:

>100_bases
TATCCTTTTGATTGGGCTTGTGACTCTTTGGGGAGTAACAAGCTCAACATTAGAATATAAGCTAAGGCGTCGCTACTGCG
CCTTAACAAAACGAAAAGGA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLDNYDNEVLKLTAGCSVVMTGDV
VESPGAGQAFELQVTDIEVAGWVDDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWV
STPLITASDCEGAGEMFRVSTLDMENLPRTDAGKVDYDKDFFGKEAFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFANLNDIAGLAEAMLKYAFNAVLTERMDDLTFFAQHVDKTVIDRLQSFVSSDFAQVDYTDAVEIL
QNCGRTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDMRLAEMDLNQEDYWWYRDMRRYGTVPHAGFGLGFERLVSYVTGVNNIRDVIPFPRAPRTANF

Sequences:

>Translated_466_residues
MSIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLDNYDNEVLKLTAGCSVVMTGDV
VESPGAGQAFELQVTDIEVAGWVDDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWV
STPLITASDCEGAGEMFRVSTLDMENLPRTDAGKVDYDKDFFGKEAFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFANLNDIAGLAEAMLKYAFNAVLTERMDDLTFFAQHVDKTVIDRLQSFVSSDFAQVDYTDAVEIL
QNCGRTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDMRLAEMDLNQEDYWWYRDMRRYGTVPHAGFGLGFERLVSYVTGVNNIRDVIPFPRAPRTANF
>Mature_465_residues
SIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLDNYDNEVLKLTAGCSVVMTGDVV
ESPGAGQAFELQVTDIEVAGWVDDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWVS
TPLITASDCEGAGEMFRVSTLDMENLPRTDAGKVDYDKDFFGKEAFLTVSGQLNAETYACALSKVYTFGPTFRAENSNTS
RHLAEFWMVEPEVAFANLNDIAGLAEAMLKYAFNAVLTERMDDLTFFAQHVDKTVIDRLQSFVSSDFAQVDYTDAVEILQ
NCGRTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLD
VLDMRLAEMDLNQEDYWWYRDMRRYGTVPHAGFGLGFERLVSYVTGVNNIRDVIPFPRAPRTANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=464, Percent_Identity=42.2413793103448, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI4758762, Length=463, Percent_Identity=28.0777537796976, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI45439306, Length=355, Percent_Identity=27.3239436619718, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=80.4721030042919, Blast_Score=810, Evalue=0.0,
Organism=Escherichia coli, GI1788173, Length=109, Percent_Identity=33.9449541284404, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17556372, Length=429, Percent_Identity=31.002331002331, Blast_Score=198, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI71984122, Length=452, Percent_Identity=29.646017699115, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17551876, Length=340, Percent_Identity=26.7647058823529, Blast_Score=105, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6319872, Length=489, Percent_Identity=35.9918200408998, Blast_Score=294, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6321807, Length=464, Percent_Identity=30.1724137931034, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6323011, Length=486, Percent_Identity=24.8971193415638, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI19922416, Length=464, Percent_Identity=34.9137931034483, Blast_Score=278, Evalue=5e-75,
Organism=Drosophila melanogaster, GI19921528, Length=479, Percent_Identity=28.1837160751566, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI17136276, Length=343, Percent_Identity=27.4052478134111, Blast_Score=99, Evalue=7e-21,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_SHEB5 (A3D3V7)

Other databases:

- EMBL:   CP000563
- RefSeq:   YP_001050289.1
- ProteinModelPortal:   A3D3V7
- SMR:   A3D3V7
- STRING:   A3D3V7
- GeneID:   4842629
- GenomeReviews:   CP000563_GR
- KEGG:   sbl:Sbal_1914
- NMPDR:   fig|325240.3.peg.2697
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- PhylomeDB:   A3D3V7
- ProtClustDB:   PRK03932
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 52151; Mature: 52020

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLDN
CCHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCCCCCCC
YDNEVLKLTAGCSVVMTGDVVESPGAGQAFELQVTDIEVAGWVDDPDTYPMAAKRHSIEH
CCCCEEEEECCCEEEEECCEECCCCCCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHH
LRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWVSTPLITASDCEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCEEEEE
TLDMENLPRTDAGKVDYDKDFFGKEAFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
ECCHHCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFANLNDIAGLAEAMLKYAFNAVLTERMDDLTFFAQHVDKTVIDRL
HHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSFVSSDFAQVDYTDAVEILQNCGRTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCCCCCHHHHHHHHHHCCCCEECCCEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDMRLAEMDLNQEDYWWY
HHHEEEEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
RDMRRYGTVPHAGFGLGFERLVSYVTGVNNIRDVIPFPRAPRTANF
HHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLDN
CHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCCCCCCC
YDNEVLKLTAGCSVVMTGDVVESPGAGQAFELQVTDIEVAGWVDDPDTYPMAAKRHSIEH
CCCCEEEEECCCEEEEECCEECCCCCCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHH
LRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWVSTPLITASDCEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCEEEEE
TLDMENLPRTDAGKVDYDKDFFGKEAFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
ECCHHCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFANLNDIAGLAEAMLKYAFNAVLTERMDDLTFFAQHVDKTVIDRL
HHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSFVSSDFAQVDYTDAVEILQNCGRTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCCCCCHHHHHHHHHHCCCCEECCCEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDMRLAEMDLNQEDYWWY
HHHEEEEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
RDMRRYGTVPHAGFGLGFERLVSYVTGVNNIRDVIPFPRAPRTANF
HHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA