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The map label for this gene is apbE [H]

Identifier: 126174119

GI number: 126174119

Start: 2193792

End: 2194697

Strand: Direct

Name: apbE [H]

Synonym: Sbal_1893

Alternate gene names: 126174119

Gene position: 2193792-2194697 (Clockwise)

Preceding gene: 126174118

Following gene: 126174120

Centisome position: 42.79

GC content: 49.34

Gene sequence:

>906_bases
ATGTCGACATCATCCCTAAAAACCGCACTTTATTCGCTGCAACGCCGTGATTGGGGTTATGTGGGCGAATTTAGGGCCAT
GGCGAGTCCCTGTGAAATACTCATTGCATGTGATCAACTTGATATCGCCGACGATATGTTGGATATGGCCGTCACTGAGG
CGCTGCGTATTGAACATAAGTACAGTCGCTTTATTGCGCAGAATTGTCTGTGGCAATTAAACCATGCCTATGGTCATAAG
CAGCTTATCGATGAAGAAACCTGGCAGTTATTGGCTTTTGCCAAACAATGTTTTCAGCTCAGTGATGGATTATTTGATAT
CTCTGCAGGGCCGTTAATGGAACTGTGGCGCTTTGATCCCAAAGCCCAATTGCCCGAACATGCCCGCATACTTGCCGCGA
AAGCCTTAGTGGGGTTTGAGCGTATCGAGTTTGATTCGCGCCATATTGAGATGCCATCGGGAATGAAATTGGATTTTGGC
GGCGTTGCTAAGGAATATGCAGTCGATAGAGTCGCCTATGAGTTGGCTGAATGTTATCCAGATATTCCTGTGCTAGTGAA
TTTTGGTGGCGATATCGCTTGTCCCGTGCCCAAAGTGAACCCATGGCAGGTGGGCATTGAAGATCCTCGCCATCTCGATC
GCGCCGCCAGTGTACTGGCGATCAGTCAGGGCGCATTAGCGACCAGCGGCGATACACGGCGCTTTTTTGAAGTAGATGGA
AAGCGTTACGGCCATATTGTCGATCCGCGTACTGGCTATCCCGTCGTCCATGCGCCGCGCTCCGTGACTGTGTTAGGGCC
AAACTGCGTGACCGCTGGAATGCTAGCGACTATGGCCATGTTACAGGGCCAAGATGCGGAAGCATTTTTACAGCAACAAG
ATGTTAAGTTTAGTATTTTCCGTTAA

Upstream 100 bases:

>100_bases
CGTTAAACTGTATGGGTAGCTTAGCTACCCATACTCAATTTACCCCTGAGCTTATTTAAGCTGAATGCCAGTGGGGTGCC
ATGTAAAGAGGTGATTTATG

Downstream 100 bases:

>100_bases
GGGTTCTTTTAAAAGGCTCTGTTAAGGACATTGAATGCGTATTATGTTGGTTGAAGACAATGAGTTATTGGCTCAAGGGA
TTTGCTTAAGTTTGGCAAAG

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSTSSLKTALYSLQRRDWGYVGEFRAMASPCEILIACDQLDIADDMLDMAVTEALRIEHKYSRFIAQNCLWQLNHAYGHK
QLIDEETWQLLAFAKQCFQLSDGLFDISAGPLMELWRFDPKAQLPEHARILAAKALVGFERIEFDSRHIEMPSGMKLDFG
GVAKEYAVDRVAYELAECYPDIPVLVNFGGDIACPVPKVNPWQVGIEDPRHLDRAASVLAISQGALATSGDTRRFFEVDG
KRYGHIVDPRTGYPVVHAPRSVTVLGPNCVTAGMLATMAMLQGQDAEAFLQQQDVKFSIFR

Sequences:

>Translated_301_residues
MSTSSLKTALYSLQRRDWGYVGEFRAMASPCEILIACDQLDIADDMLDMAVTEALRIEHKYSRFIAQNCLWQLNHAYGHK
QLIDEETWQLLAFAKQCFQLSDGLFDISAGPLMELWRFDPKAQLPEHARILAAKALVGFERIEFDSRHIEMPSGMKLDFG
GVAKEYAVDRVAYELAECYPDIPVLVNFGGDIACPVPKVNPWQVGIEDPRHLDRAASVLAISQGALATSGDTRRFFEVDG
KRYGHIVDPRTGYPVVHAPRSVTVLGPNCVTAGMLATMAMLQGQDAEAFLQQQDVKFSIFR
>Mature_300_residues
STSSLKTALYSLQRRDWGYVGEFRAMASPCEILIACDQLDIADDMLDMAVTEALRIEHKYSRFIAQNCLWQLNHAYGHKQ
LIDEETWQLLAFAKQCFQLSDGLFDISAGPLMELWRFDPKAQLPEHARILAAKALVGFERIEFDSRHIEMPSGMKLDFGG
VAKEYAVDRVAYELAECYPDIPVLVNFGGDIACPVPKVNPWQVGIEDPRHLDRAASVLAISQGALATSGDTRRFFEVDGK
RYGHIVDPRTGYPVVHAPRSVTVLGPNCVTAGMLATMAMLQGQDAEAFLQQQDVKFSIFR

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=197, Percent_Identity=33.502538071066, Blast_Score=98, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 33661; Mature: 33530

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSSLKTALYSLQRRDWGYVGEFRAMASPCEILIACDQLDIADDMLDMAVTEALRIEHK
CCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
YSRFIAQNCLWQLNHAYGHKQLIDEETWQLLAFAKQCFQLSDGLFDISAGPLMELWRFDP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHCCCC
KAQLPEHARILAAKALVGFERIEFDSRHIEMPSGMKLDFGGVAKEYAVDRVAYELAECYP
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEECCCCHHHHHHHHHHHHHHHHHCC
DIPVLVNFGGDIACPVPKVNPWQVGIEDPRHLDRAASVLAISQGALATSGDTRRFFEVDG
CCCEEEECCCCEECCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCEECCCCCCEEEEECC
KRYGHIVDPRTGYPVVHAPRSVTVLGPNCVTAGMLATMAMLQGQDAEAFLQQQDVKFSIF
CCCCCCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEC
R
C
>Mature Secondary Structure 
STSSLKTALYSLQRRDWGYVGEFRAMASPCEILIACDQLDIADDMLDMAVTEALRIEHK
CCHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
YSRFIAQNCLWQLNHAYGHKQLIDEETWQLLAFAKQCFQLSDGLFDISAGPLMELWRFDP
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHCCCC
KAQLPEHARILAAKALVGFERIEFDSRHIEMPSGMKLDFGGVAKEYAVDRVAYELAECYP
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEECCCCHHHHHHHHHHHHHHHHHCC
DIPVLVNFGGDIACPVPKVNPWQVGIEDPRHLDRAASVLAISQGALATSGDTRRFFEVDG
CCCEEEECCCCEECCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCEECCCCCCEEEEECC
KRYGHIVDPRTGYPVVHAPRSVTVLGPNCVTAGMLATMAMLQGQDAEAFLQQQDVKFSIF
CCCCCCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]