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The map label for this gene is hypB [H]

Identifier: 126174109

GI number: 126174109

Start: 2181580

End: 2182425

Strand: Reverse

Name: hypB [H]

Synonym: Sbal_1883

Alternate gene names: 126174109

Gene position: 2182425-2181580 (Counterclockwise)

Preceding gene: 126174110

Following gene: 126174108

Centisome position: 42.56

GC content: 47.87

Gene sequence:

>846_bases
ATGTGTAAAGACTGCGGCTGCTCCCTTACCCGCCACGACCATGATCATTTAGGCGCGCATTCACATGTTGATAGTCATGA
CCATAGCCATGATCACGGGCACAGTCATGATCACGGCCATTCGCATGAGCATGGCGCATCCCATAGCCCATCGCATAGTC
ATAGCGAGTTACACACCAATCCTCAGTTAAACGATAAAAAAACCTTGTCAGTGATCCACAAAATTTTAGATAAAAATGAT
GTCGAAGCCGGTCATAACCGCGCCCACTTTGAGGCACATAACATCACGGCCTTCAACATCATGAGTAGCCCAGGCAGCGG
TAAAACTACCCTTTTAGAAAATCTCAAAGAATACACCAAGCTCAACTATGCGGTGATTGAAGGCGACTTAGAAACCTCCC
GCGATGCCGACCGCTTAATCGCGAAAGGCATTACAGCCTATCAAATTCAAACGGGCTCGGCCTGTCACCTTGACGCCTTT
ATGGTGCACGGCGCCCTGCATCATCTGCCACTTGAAGGGCTGGATATTTGCTTTGTCGAAAACGTCGGCAATCTCGTCTG
CCCAGCCAGTTATGACGTAGGTACCCACAAAAATATCGTGCTGCTGTCCGTGCCAGAAGGCGATGATAAGATTGAGAAAT
ATCCTGTGATGTTCCGCCGCGCAGATGTAGTGTTTATCACTAAGTGCGATCTACTGCCCTATTTTGATTTCAAGCTGGAC
GAAGCCAGAGCACAGCTTAAAAAACTCAATCCAGCAACTCAAATCATTGAAGTCTCCATCAAAGATGGCGACTCCATGCA
GGCTGTGGCAGCTTGGCTTAAAGACAATATTCGAGGTGCACAATAA

Upstream 100 bases:

>100_bases
CACACTCAACATTAGCGTAACCAAATTAACGATCTGTACGTCAGCATTCACAATTCGTCAGGCAAAGTCCTCGCACTCTG
CCGATTCAAGGAGAGGTAAA

Downstream 100 bases:

>100_bases
TGTGCTTGTCCATACCTTCCCAAGTGGTGGCGGTCGATATTGAGCGCCAGAGTGTCACGGTCGATACCTTAGGCGTACGC
CGCGATGTCAGCAGTCATTT

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MCKDCGCSLTRHDHDHLGAHSHVDSHDHSHDHGHSHDHGHSHEHGASHSPSHSHSELHTNPQLNDKKTLSVIHKILDKND
VEAGHNRAHFEAHNITAFNIMSSPGSGKTTLLENLKEYTKLNYAVIEGDLETSRDADRLIAKGITAYQIQTGSACHLDAF
MVHGALHHLPLEGLDICFVENVGNLVCPASYDVGTHKNIVLLSVPEGDDKIEKYPVMFRRADVVFITKCDLLPYFDFKLD
EARAQLKKLNPATQIIEVSIKDGDSMQAVAAWLKDNIRGAQ

Sequences:

>Translated_281_residues
MCKDCGCSLTRHDHDHLGAHSHVDSHDHSHDHGHSHDHGHSHEHGASHSPSHSHSELHTNPQLNDKKTLSVIHKILDKND
VEAGHNRAHFEAHNITAFNIMSSPGSGKTTLLENLKEYTKLNYAVIEGDLETSRDADRLIAKGITAYQIQTGSACHLDAF
MVHGALHHLPLEGLDICFVENVGNLVCPASYDVGTHKNIVLLSVPEGDDKIEKYPVMFRRADVVFITKCDLLPYFDFKLD
EARAQLKKLNPATQIIEVSIKDGDSMQAVAAWLKDNIRGAQ
>Mature_281_residues
MCKDCGCSLTRHDHDHLGAHSHVDSHDHSHDHGHSHDHGHSHEHGASHSPSHSHSELHTNPQLNDKKTLSVIHKILDKND
VEAGHNRAHFEAHNITAFNIMSSPGSGKTTLLENLKEYTKLNYAVIEGDLETSRDADRLIAKGITAYQIQTGSACHLDAF
MVHGALHHLPLEGLDICFVENVGNLVCPASYDVGTHKNIVLLSVPEGDDKIEKYPVMFRRADVVFITKCDLLPYFDFKLD
EARAQLKKLNPATQIIEVSIKDGDSMQAVAAWLKDNIRGAQ

Specific function: Plays a role in both the hydrogenase and the urease nickel cofactor insertion step [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=226, Percent_Identity=43.8053097345133, Blast_Score=186, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 31147; Mature: 31147

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKDCGCSLTRHDHDHLGAHSHVDSHDHSHDHGHSHDHGHSHEHGASHSPSHSHSELHTN
CCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PQLNDKKTLSVIHKILDKNDVEAGHNRAHFEAHNITAFNIMSSPGSGKTTLLENLKEYTK
CCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHH
LNYAVIEGDLETSRDADRLIAKGITAYQIQTGSACHLDAFMVHGALHHLPLEGLDICFVE
CCEEEEECCCCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEC
NVGNLVCPASYDVGTHKNIVLLSVPEGDDKIEKYPVMFRRADVVFITKCDLLPYFDFKLD
CCCCEECCCCCCCCCCCCEEEEECCCCCCHHHHCCCEEEECCEEEEEEECCCCCCCCEEH
EARAQLKKLNPATQIIEVSIKDGDSMQAVAAWLKDNIRGAQ
HHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MCKDCGCSLTRHDHDHLGAHSHVDSHDHSHDHGHSHDHGHSHEHGASHSPSHSHSELHTN
CCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PQLNDKKTLSVIHKILDKNDVEAGHNRAHFEAHNITAFNIMSSPGSGKTTLLENLKEYTK
CCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHH
LNYAVIEGDLETSRDADRLIAKGITAYQIQTGSACHLDAFMVHGALHHLPLEGLDICFVE
CCEEEEECCCCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEC
NVGNLVCPASYDVGTHKNIVLLSVPEGDDKIEKYPVMFRRADVVFITKCDLLPYFDFKLD
CCCCEECCCCCCCCCCCCEEEEECCCCCCHHHHCCCEEEECCEEEEEEECCCCCCCCEEH
EARAQLKKLNPATQIIEVSIKDGDSMQAVAAWLKDNIRGAQ
HHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682; 11123699 [H]