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The map label for this gene is msbB [H]

Identifier: 126174102

GI number: 126174102

Start: 2176221

End: 2177162

Strand: Direct

Name: msbB [H]

Synonym: Sbal_1876

Alternate gene names: 126174102

Gene position: 2176221-2177162 (Clockwise)

Preceding gene: 126174101

Following gene: 126174103

Centisome position: 42.44

GC content: 49.04

Gene sequence:

>942_bases
TTGTCAAGACAGCCCAAACATTTTGACCGTCGCTTTAAACTCGCCTTATTACATCCTAAATACTGGGCCACTTGGTTGGC
GATTGGTCTACTAGTGATTTTCGGGCTCATGCCCGCATGGCTGCGTGATCCCATTGCAAGATTATTGGCAAGATTAGTGA
TGCCGATTGCCAAAAAGCCCATTAGTGTTGCAAGAGCCAACTTAAGAGCTTGCTTTCCTGAACAATCTGCCGCCGAGATC
GAAGCGTTAATCCGTGAGAACGTACAAAACTTCGTTTTAGTCTTGTTAGCACAGGGCGAATTGCTGGTGCGCTCAAAAGC
GCATTTGCGTCGTCGAGTGAATTTAATCGGCTTTGAGCATGTGACGAAAGCACAAGCGGCGGGGCAACCGATCATTTTCA
TCATGCCCCATGTGTGGCCAATCGATTATGCTGGTTTACGCCTTAACCTTGAGTTGCCTATGGTGACGATGGCCAAAGCC
CATAAAAACGGCTTATTCAATTGGTTTAGTAATCGTGTGCGCAGCAGTTGTGGTGGCCATGTATACATGCGCGAGGCGGG
AATTCGTGCGTTGTTAGCTGAGCTTAAGTGCGGTAACAGTTTCTTTTATCTACCCGACGAAGATTTAGGCCCAGAACAAA
GCGTGTTTGCGCCATTTTTAGGCACAGTGAAAGCAACGCTGCCTGTCGTTGGGCGTTTAGCACAGGCGGGTAATGCCCAA
GTGCTGCCAGTAAAGATTGGCTACAATCAAACCTCACGGCAGTTTGATCTCACTGTGATGACGGCCGTTGCGCCCGAAGA
CATGGTCGGCAAGGAAAACGAGGCGCTGGCGCTGAACAAAGTGGTCGAGCAAGTTATATTAGCTTACCCAGAGCAATATA
TGTGGTTCCTACGGGTGCTCAAGACTCGCCCAGAGGGTGAAGCTTCTATCTACGGTCAATGA

Upstream 100 bases:

>100_bases
GTTTGTTTGATGGGAAAGCCACTCCTTAGAGAGTGGCTTTCCTGTTTATTTTTTTGTGCAATATCTCCATTATTTCTATC
CACTGTCTGAGGTGAATTCT

Downstream 100 bases:

>100_bases
CGGGCCTGTCAATTTAGTATGGCTAAAAATGGCTTTGAGCGCTCAGTGCTCAAAGCCATTTTTGTTTTAGCAAGCTGTGC
TTACCAGTGATGAGCATTCT

Product: lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSRQPKHFDRRFKLALLHPKYWATWLAIGLLVIFGLMPAWLRDPIARLLARLVMPIAKKPISVARANLRACFPEQSAAEI
EALIRENVQNFVLVLLAQGELLVRSKAHLRRRVNLIGFEHVTKAQAAGQPIIFIMPHVWPIDYAGLRLNLELPMVTMAKA
HKNGLFNWFSNRVRSSCGGHVYMREAGIRALLAELKCGNSFFYLPDEDLGPEQSVFAPFLGTVKATLPVVGRLAQAGNAQ
VLPVKIGYNQTSRQFDLTVMTAVAPEDMVGKENEALALNKVVEQVILAYPEQYMWFLRVLKTRPEGEASIYGQ

Sequences:

>Translated_313_residues
MSRQPKHFDRRFKLALLHPKYWATWLAIGLLVIFGLMPAWLRDPIARLLARLVMPIAKKPISVARANLRACFPEQSAAEI
EALIRENVQNFVLVLLAQGELLVRSKAHLRRRVNLIGFEHVTKAQAAGQPIIFIMPHVWPIDYAGLRLNLELPMVTMAKA
HKNGLFNWFSNRVRSSCGGHVYMREAGIRALLAELKCGNSFFYLPDEDLGPEQSVFAPFLGTVKATLPVVGRLAQAGNAQ
VLPVKIGYNQTSRQFDLTVMTAVAPEDMVGKENEALALNKVVEQVILAYPEQYMWFLRVLKTRPEGEASIYGQ
>Mature_312_residues
SRQPKHFDRRFKLALLHPKYWATWLAIGLLVIFGLMPAWLRDPIARLLARLVMPIAKKPISVARANLRACFPEQSAAEIE
ALIRENVQNFVLVLLAQGELLVRSKAHLRRRVNLIGFEHVTKAQAAGQPIIFIMPHVWPIDYAGLRLNLELPMVTMAKAH
KNGLFNWFSNRVRSSCGGHVYMREAGIRALLAELKCGNSFFYLPDEDLGPEQSVFAPFLGTVKATLPVVGRLAQAGNAQV
LPVKIGYNQTSRQFDLTVMTAVAPEDMVGKENEALALNKVVEQVILAYPEQYMWFLRVLKTRPEGEASIYGQ

Specific function: Transfers myristate or laurate, activated on ACP, to (KDO)2-(lauroyl)-lipid IVA [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI1788161, Length=308, Percent_Identity=32.7922077922078, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI87082094, Length=307, Percent_Identity=30.6188925081433, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1787292, Length=304, Percent_Identity=28.9473684210526, Blast_Score=145, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011921 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 35195; Mature: 35064

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQPKHFDRRFKLALLHPKYWATWLAIGLLVIFGLMPAWLRDPIARLLARLVMPIAKKP
CCCCCCCHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ISVARANLRACFPEQSAAEIEALIRENVQNFVLVLLAQGELLVRSKAHLRRRVNLIGFEH
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHH
VTKAQAAGQPIIFIMPHVWPIDYAGLRLNLELPMVTMAKAHKNGLFNWFSNRVRSSCGGH
HHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHCCCCE
VYMREAGIRALLAELKCGNSFFYLPDEDLGPEQSVFAPFLGTVKATLPVVGRLAQAGNAQ
EEEHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLPVKIGYNQTSRQFDLTVMTAVAPEDMVGKENEALALNKVVEQVILAYPEQYMWFLRVL
EEEEEECCCCCCCEEEEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
KTRPEGEASIYGQ
HCCCCCCCCCCCC
>Mature Secondary Structure 
SRQPKHFDRRFKLALLHPKYWATWLAIGLLVIFGLMPAWLRDPIARLLARLVMPIAKKP
CCCCCCHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ISVARANLRACFPEQSAAEIEALIRENVQNFVLVLLAQGELLVRSKAHLRRRVNLIGFEH
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHH
VTKAQAAGQPIIFIMPHVWPIDYAGLRLNLELPMVTMAKAHKNGLFNWFSNRVRSSCGGH
HHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHCCCCE
VYMREAGIRALLAELKCGNSFFYLPDEDLGPEQSVFAPFLGTVKATLPVVGRLAQAGNAQ
EEEHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLPVKIGYNQTSRQFDLTVMTAVAPEDMVGKENEALALNKVVEQVILAYPEQYMWFLRVL
EEEEEECCCCCCCEEEEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
KTRPEGEASIYGQ
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]