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The map label for this gene is pheS [H]

Identifier: 126174099

GI number: 126174099

Start: 2172394

End: 2173413

Strand: Direct

Name: pheS [H]

Synonym: Sbal_1873

Alternate gene names: 126174099

Gene position: 2172394-2173413 (Clockwise)

Preceding gene: 126174097

Following gene: 126174100

Centisome position: 42.37

GC content: 45.29

Gene sequence:

>1020_bases
TTGTTTATCAAGCGCGACTATGCAGTGGAAGAGAAAATGCAGCAGTTAACTGAGATCGTAGAACAAGCCTTAGTCATTAT
TGACCAGGCCAGTGATCTAAAAGCACTGGATGATATCCGTGTCGATTACCTTGGTAAGAAAGGTAAGATCACCGACATGA
TGAAAATGATGGGTAGCTTAAGCCCTGAAGAAAAGCCAGCCTTTGGCCAAGCGGTCAATGATGCTAAACAGGCGATTCAA
CAAAAATTAACTGAGCGCATCGATGGTCTGAAGAGTTCGGAACTGGAAGCCAAATTAATCGCTGAAAAGATTGATGTGAC
TTTGCCAGGCCGCACCCAAGAGATCGGTGGCTTACATCCAGTGACTCGCACCATTGAACGTATCGAAACCTTTTTCGGGG
AATTAGGGTTCTCGGTAAAGCAGGGTCCTGAAATTGAAGATGATTTCCACAATTTCGATGCGCTGAATATCTCTGAACAC
CACCCAGCCCGTGCCGATCAGGATACCTTTTATTTCAATCCTAAACTGATGCTGCGTACCCAAACCTCGGGCGTGCAAAT
CCGTACTATGGAAACTGAAAAGCCACCATTACGCATTATTTCTCCGGGTCGTGTTTATCGTAACGATTACGACCAAACGC
ACACACCAATGTTCCACCAAGTGGAAGGGCTGTTGGTTGATGAGCATGTGAACTTTGCCGAATTGAAAGGCATTTTGCAT
GACTTCCTGCGTAACTTCTTCGAAGAAGATCTGCAAGTGCGTTTCCGTCCATCTTACTTCCCATTCACAGAACCTTCAGC
GGAAATGGACGTAATGGGCAAAAATGGTAAATGGCTAGAAGTGGGTGGCTGCGGTATGGTACATCCTAATGTGCTGCGCA
GCGTTGGCATAGATCCAGAAAAATACTCTGGTTTTGCTTTTGGTATGGGTGTCGAGCGCTTAACTATGTTGCGTTACGGC
GTAAACGATTTACGTGCGTTTTTCGAAAACGACCTACGTTTCCTGAAGCAATTTAAATAA

Upstream 100 bases:

>100_bases
ATTTCTATCCTTTTATTTCGTAATAGCTAGCAAAGCGTCTGGCATTAACGCCCGATAACCTGAGCACCCAAATAGCCTGA
AAGTTTGGCGCCCATAGCAC

Downstream 100 bases:

>100_bases
CGGAGCTGTAATAGCATGAAATTTAGCGAATCTTGGCTTCGTGAATGGGTAAACCCTTCAGTCAGCCGTGAAGCATTATC
GCACCAGATCACTATGGCCG

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MFIKRDYAVEEKMQQLTEIVEQALVIIDQASDLKALDDIRVDYLGKKGKITDMMKMMGSLSPEEKPAFGQAVNDAKQAIQ
QKLTERIDGLKSSELEAKLIAEKIDVTLPGRTQEIGGLHPVTRTIERIETFFGELGFSVKQGPEIEDDFHNFDALNISEH
HPARADQDTFYFNPKLMLRTQTSGVQIRTMETEKPPLRIISPGRVYRNDYDQTHTPMFHQVEGLLVDEHVNFAELKGILH
DFLRNFFEEDLQVRFRPSYFPFTEPSAEMDVMGKNGKWLEVGGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYG
VNDLRAFFENDLRFLKQFK

Sequences:

>Translated_339_residues
MFIKRDYAVEEKMQQLTEIVEQALVIIDQASDLKALDDIRVDYLGKKGKITDMMKMMGSLSPEEKPAFGQAVNDAKQAIQ
QKLTERIDGLKSSELEAKLIAEKIDVTLPGRTQEIGGLHPVTRTIERIETFFGELGFSVKQGPEIEDDFHNFDALNISEH
HPARADQDTFYFNPKLMLRTQTSGVQIRTMETEKPPLRIISPGRVYRNDYDQTHTPMFHQVEGLLVDEHVNFAELKGILH
DFLRNFFEEDLQVRFRPSYFPFTEPSAEMDVMGKNGKWLEVGGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYG
VNDLRAFFENDLRFLKQFK
>Mature_339_residues
MFIKRDYAVEEKMQQLTEIVEQALVIIDQASDLKALDDIRVDYLGKKGKITDMMKMMGSLSPEEKPAFGQAVNDAKQAIQ
QKLTERIDGLKSSELEAKLIAEKIDVTLPGRTQEIGGLHPVTRTIERIETFFGELGFSVKQGPEIEDDFHNFDALNISEH
HPARADQDTFYFNPKLMLRTQTSGVQIRTMETEKPPLRIISPGRVYRNDYDQTHTPMFHQVEGLLVDEHVNFAELKGILH
DFLRNFFEEDLQVRFRPSYFPFTEPSAEMDVMGKNGKWLEVGGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYG
VNDLRAFFENDLRFLKQFK

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=257, Percent_Identity=33.0739299610895, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI5729820, Length=278, Percent_Identity=32.7338129496403, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1788007, Length=327, Percent_Identity=72.782874617737, Blast_Score=513, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI32566635, Length=238, Percent_Identity=34.8739495798319, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32563657, Length=259, Percent_Identity=30.8880308880309, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17508957, Length=259, Percent_Identity=30.8880308880309, Blast_Score=124, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6321087, Length=366, Percent_Identity=28.9617486338798, Blast_Score=132, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6325304, Length=152, Percent_Identity=33.5526315789474, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI18858079, Length=258, Percent_Identity=31.7829457364341, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17137424, Length=289, Percent_Identity=28.719723183391, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 38861; Mature: 38861

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIKRDYAVEEKMQQLTEIVEQALVIIDQASDLKALDDIRVDYLGKKGKITDMMKMMGSL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCC
SPEEKPAFGQAVNDAKQAIQQKLTERIDGLKSSELEAKLIAEKIDVTLPGRTQEIGGLHP
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCEECCCCCHHHCCCCH
VTRTIERIETFFGELGFSVKQGPEIEDDFHNFDALNISEHHPARADQDTFYFNPKLMLRT
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEEEECCEEEEEE
QTSGVQIRTMETEKPPLRIISPGRVYRNDYDQTHTPMFHQVEGLLVDEHVNFAELKGILH
ECCCEEEEEECCCCCCEEEECCCHHHCCCCCCCCCCHHHHHHCEEEECCCCHHHHHHHHH
DFLRNFFEEDLQVRFRPSYFPFTEPSAEMDVMGKNGKWLEVGGCGMVHPNVLRSVGIDPE
HHHHHHHHHHHEEEECCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCHHHHHHCCCCHH
KYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK
HCCCEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFIKRDYAVEEKMQQLTEIVEQALVIIDQASDLKALDDIRVDYLGKKGKITDMMKMMGSL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCC
SPEEKPAFGQAVNDAKQAIQQKLTERIDGLKSSELEAKLIAEKIDVTLPGRTQEIGGLHP
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCEECCCCCHHHCCCCH
VTRTIERIETFFGELGFSVKQGPEIEDDFHNFDALNISEHHPARADQDTFYFNPKLMLRT
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEEEECCEEEEEE
QTSGVQIRTMETEKPPLRIISPGRVYRNDYDQTHTPMFHQVEGLLVDEHVNFAELKGILH
ECCCEEEEEECCCCCCEEEECCCHHHCCCCCCCCCCHHHHHHCEEEECCCCHHHHHHHHH
DFLRNFFEEDLQVRFRPSYFPFTEPSAEMDVMGKNGKWLEVGGCGMVHPNVLRSVGIDPE
HHHHHHHHHHHEEEECCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCHHHHHHCCCCHH
KYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK
HCCCEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA