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The map label for this gene is rnd [H]

Identifier: 126174091

GI number: 126174091

Start: 2165176

End: 2166285

Strand: Direct

Name: rnd [H]

Synonym: Sbal_1865

Alternate gene names: 126174091

Gene position: 2165176-2166285 (Clockwise)

Preceding gene: 126174090

Following gene: 126174095

Centisome position: 42.23

GC content: 46.31

Gene sequence:

>1110_bases
TTGTCAGCGTTTCAATATGTGAGTGATGAAGCAAGCCTTAATGCCCTCGTTGCCCAATATAAACAGAGTAAGATACTCGT
GTTAGATACCGAGTTTGTTCGTACTCGTACTTATTATGCCAAGTTAGGTTTGATCCAAGCCTATGATGGTAAAACCTTAG
CTTTGATTGATCCGGTGGCTTTACCTGATTTAGCCCAGTTTTGGGCGCTGTTATCGGACCCGAATATCGTTAAGCTTGTG
CATTCCTGTAGTGAAGACTTAGAAGTCTTTGCCCACTACGGTAAATGTCAGCCTACGCCTTTATTTGATAGCCAAATTGC
CGCCTCTTTGTGCGGTATGGGCCATGGTGTGGGTTATGCCAAGTTAGTTGAAACTTGCTTGGGTGAAGTGATCGATAAAG
GCGAGTCGCGTACAGATTGGATCCGTCGTCCTTTAACGGAAGCCCAGTTAAGCTACGCCGCTAATGACGTCTTGTACTTG
TATCAGCTCTATCCTCAACTGGAAGCGAAACTCAGCGCCCAAGGCCGTTTAGCTTGGTTATACGAGGAAGGGGAAAGGAT
GACCCTGGGCAGGCTTGCAGATCCTGATCTCGACACGGCTTATTTGAAAGTGAAAAATGCTTTCCAACTGACCGAAATCC
AATTGGCTTACCTTAAAGTGCTTGCTAAGTGGCGTCTTGAAAAAGCCTTAGTGCGTGATTTAGCCCTAGGTTTTGTGGTC
AAAGATCATGGTCTTATCGCATTAGCGAAGAAGCAACCTAAATCCTCGGCTGACTTGTTTAAGCTCAATGATTTGACTGA
GCAAGAAAAACGTATCCACGGCAAAGATCTATTACGTGTGTTGCAAACCGCTGATTTGGTCAATTTACCCGAGTTAGTGG
ATGTGCTGGCGTTGAAGTCGGGTTATAAATCGGCCTTTAAGGCGATTAAAAGCTGCTTAGTCGAGTTGTGTGAACAGCAT
GATGTGCCGCAGGAAATGCTCGGTTCTAAACGCCATATCCATGAGTTTTTGCAATGGCGTTGGGATAAGCAACAAGGGGA
TTTGCCCGCGGTGTTATGCGGATGGCGGGGCGAGATTGCCGCTGAGTCCCTAGCTAAGCTTGAGGTCTAA

Upstream 100 bases:

>100_bases
GAGCTTAGAGACGAAGCTAAGCGCGCGTAAGATTGAAGCCGGCATTTGCCGGCTTTTGTTTTTATGGACTGTGATTGACC
CACAGGATCTGGAGAAGAAT

Downstream 100 bases:

>100_bases
GGCTTTCAATCTAGCCTTTAAAACTAGTGCGTGAAGTCTTGTACTTTATGTGCAGTATTTGAAACTTACCGATAGCCGAA
AAACAGCCAACAAAAAGCGT

Product: ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSAFQYVSDEASLNALVAQYKQSKILVLDTEFVRTRTYYAKLGLIQAYDGKTLALIDPVALPDLAQFWALLSDPNIVKLV
HSCSEDLEVFAHYGKCQPTPLFDSQIAASLCGMGHGVGYAKLVETCLGEVIDKGESRTDWIRRPLTEAQLSYAANDVLYL
YQLYPQLEAKLSAQGRLAWLYEEGERMTLGRLADPDLDTAYLKVKNAFQLTEIQLAYLKVLAKWRLEKALVRDLALGFVV
KDHGLIALAKKQPKSSADLFKLNDLTEQEKRIHGKDLLRVLQTADLVNLPELVDVLALKSGYKSAFKAIKSCLVELCEQH
DVPQEMLGSKRHIHEFLQWRWDKQQGDLPAVLCGWRGEIAAESLAKLEV

Sequences:

>Translated_369_residues
MSAFQYVSDEASLNALVAQYKQSKILVLDTEFVRTRTYYAKLGLIQAYDGKTLALIDPVALPDLAQFWALLSDPNIVKLV
HSCSEDLEVFAHYGKCQPTPLFDSQIAASLCGMGHGVGYAKLVETCLGEVIDKGESRTDWIRRPLTEAQLSYAANDVLYL
YQLYPQLEAKLSAQGRLAWLYEEGERMTLGRLADPDLDTAYLKVKNAFQLTEIQLAYLKVLAKWRLEKALVRDLALGFVV
KDHGLIALAKKQPKSSADLFKLNDLTEQEKRIHGKDLLRVLQTADLVNLPELVDVLALKSGYKSAFKAIKSCLVELCEQH
DVPQEMLGSKRHIHEFLQWRWDKQQGDLPAVLCGWRGEIAAESLAKLEV
>Mature_368_residues
SAFQYVSDEASLNALVAQYKQSKILVLDTEFVRTRTYYAKLGLIQAYDGKTLALIDPVALPDLAQFWALLSDPNIVKLVH
SCSEDLEVFAHYGKCQPTPLFDSQIAASLCGMGHGVGYAKLVETCLGEVIDKGESRTDWIRRPLTEAQLSYAANDVLYLY
QLYPQLEAKLSAQGRLAWLYEEGERMTLGRLADPDLDTAYLKVKNAFQLTEIQLAYLKVLAKWRLEKALVRDLALGFVVK
DHGLIALAKKQPKSSADLFKLNDLTEQEKRIHGKDLLRVLQTADLVNLPELVDVLALKSGYKSAFKAIKSCLVELCEQHD
VPQEMLGSKRHIHEFLQWRWDKQQGDLPAVLCGWRGEIAAESLAKLEV

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4505917, Length=239, Percent_Identity=26.3598326359833, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI50301240, Length=239, Percent_Identity=26.3598326359833, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788105, Length=368, Percent_Identity=42.9347826086957, Blast_Score=281, Evalue=4e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 41468; Mature: 41337

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFQYVSDEASLNALVAQYKQSKILVLDTEFVRTRTYYAKLGLIQAYDGKTLALIDPVA
CCCHHHCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCEEEECCCCEEEEECCCC
LPDLAQFWALLSDPNIVKLVHSCSEDLEVFAHYGKCQPTPLFDSQIAASLCGMGHGVGYA
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHH
KLVETCLGEVIDKGESRTDWIRRPLTEAQLSYAANDVLYLYQLYPQLEAKLSAQGRLAWL
HHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
YEEGERMTLGRLADPDLDTAYLKVKNAFQLTEIQLAYLKVLAKWRLEKALVRDLALGFVV
EECCCEEEECCCCCCCCCHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
KDHGLIALAKKQPKSSADLFKLNDLTEQEKRIHGKDLLRVLQTADLVNLPELVDVLALKS
ECCCEEEEECCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
GYKSAFKAIKSCLVELCEQHDVPQEMLGSKRHIHEFLQWRWDKQQGDLPAVLCGWRGEIA
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCEEEECCCCHHH
AESLAKLEV
HHHHHHCCC
>Mature Secondary Structure 
SAFQYVSDEASLNALVAQYKQSKILVLDTEFVRTRTYYAKLGLIQAYDGKTLALIDPVA
CCHHHCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCEEEECCCCEEEEECCCC
LPDLAQFWALLSDPNIVKLVHSCSEDLEVFAHYGKCQPTPLFDSQIAASLCGMGHGVGYA
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHH
KLVETCLGEVIDKGESRTDWIRRPLTEAQLSYAANDVLYLYQLYPQLEAKLSAQGRLAWL
HHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
YEEGERMTLGRLADPDLDTAYLKVKNAFQLTEIQLAYLKVLAKWRLEKALVRDLALGFVV
EECCCEEEECCCCCCCCCHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
KDHGLIALAKKQPKSSADLFKLNDLTEQEKRIHGKDLLRVLQTADLVNLPELVDVLALKS
ECCCEEEEECCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
GYKSAFKAIKSCLVELCEQHDVPQEMLGSKRHIHEFLQWRWDKQQGDLPAVLCGWRGEIA
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCEEEECCCCHHH
AESLAKLEV
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]