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The map label for this gene is speA

Identifier: 126173995

GI number: 126173995

Start: 2058303

End: 2060216

Strand: Direct

Name: speA

Synonym: Sbal_1768

Alternate gene names: 126173995

Gene position: 2058303-2060216 (Clockwise)

Preceding gene: 126173994

Following gene: 126173996

Centisome position: 40.14

GC content: 45.45

Gene sequence:

>1914_bases
ATGAATGATTGGTCTATTGATGATGCTCGTGCTGGGTACAATGTTACTCACTGGAGCCAAGGTTTTTATGGGATCAGCGA
TCACGGTGAGGTGACAGTGTCACCGGATCCAAAAAATCCTGATTACAAGATTGGCTTAAATGAGCTAGCCAAAGACATGG
TTAAAGCGGGCGTCGCTTTACCTGTACTAGTTCGTTTTCCGCAGATCCTGCACCACAGAGTGAACAGTTTGTGCCAAGCA
TTCGACCAAGCGATACAGAAGTACGAGTATCAGGCGGACTATTTGCTGGTTTACCCCATTAAAGTAAACCAACAGCAAAC
TGTGGTGGAAGAGATCCTGGCGAGTCAGGCATCAAAAGAAGTACCACAACTGGGTTTAGAAGCAGGCAGTAAGCCTGAGC
TGATGGCTGTGTTAGCCATGGCGCAAAAAGCCAGTTCAGTCATTGTGTGTAATGGTTATAAAGATAATGAATATATCCGT
TTAGCATTGATTGGTGAAAAGTTAGGCCACAAGGTTTACATCGTTTTAGAAAAACTGTCTGAACTGAAAATGGTGTTAGC
GGAATCTAAGCGTCTTGGTGTGACACCGCGTTTAGGTCTGCGTGCGCGTTTAGCGTTCCAAGGCAAAGGCAAATGGCAGG
CGAGCGGCGGTGAGAAGTCTAAGTTCGGTCTATCTGCTGCACAAATTTTGCTAGTTGTTGAACAACTTAAGCAAAACGAT
ATGCTAGATTCGCTGCAATTGCTGCATTTCCACTTAGGTTCGCAAATCGCTAACATTCGTGATATTCGCCAAGGTGTGAG
TGAAGCGGGTCGTTTCTATTGTGAATTACGTGCATTAGGCGCAAGCGTTAACTGCTTCGACGTCGGTGGTGGTTTAGCGG
TGGATTACGATGGCACACGTAGCCAAAGTAATAACTCGATGAACTATGGCCTGACCGAATACGCCAACAATATCGTTAAC
GTATTGACCGACATCTGTAATGAATACGAGCAGCCTATGCCACGTATTATTTCAGAGTCTGGCCGTTACTTAACCGCGCA
CCATGCTGTGCTGATTACCGATGTTATCGGTACTGAAGCTTATCAGCCTGAAGATATTCAACCGCCAGCGGAAGAGTCAC
CACAGTTATTGCATAACATGTGGCATTCATGGTCTGAGCTTAGTGGTCGCGCCGATCAACGTGCCTTGATTGAGATTTAT
CACGATAGCCAAAGTGACTTACAAGAAGCGCATTCGCTATTTGCTCTTGGTCAATTGAGCTTGGCAGAACGTGCTTGGGC
TGAACAAGCTAACCTGCGTGTTTGCCATGAAGTGCAAGGACTATTGAGTGCGAAGAACCGTTATCACAGACCTATCATTG
ATGAACTCAATGAAAAGTTAGCCGATAAGTTCTTTGTTAACTTCTCATTATTCCAGTCATTACCCGATGCTTGGGGTATT
GACCAAGTGTTCCCAGTATTGCCGTTATCGGGTTTAGATAAAGCCCCTGAGCGCCGTGCTGTCATGCTCGATATTACCTG
TGACTCTGACGGTATTGTCGATCAATACGTTGATGGTCAAGGGATTGAAACCACATTGCCAGTACCAGCCTGGAGTGCGG
ATAGCCCGTACCTGATTGGTTTCTTCCTTGTGGGCGCATACCAAGAAATCTTGGGTGATATGCATAACCTGTTTGGTGAT
ACTAACTCTGCGGTTGTTCGCATCGAAGATAACGGTGTGACTAACATTGAATCGGTATTAGCGGGTGATACTGTCGCTGA
CGTATTGCGTTACGTTAACTTAGATGCAGTGGCCTTTATGCGCACTTACGAAGAGTTAGTGAATTTGCATATTGCCGAAG
ATGAACGCGCACAAATTCTAGAAGAACTGCAAGTTGGCCTGAAAGGTTACACTTACTTGGAAGATTTTTCTTAA

Upstream 100 bases:

>100_bases
GTCAGGTAAGGTGTCCCTTTGCCTGGGTTTGTCGAACGGGCGGTTGTGCTATTAAGCCATAACCGTTTAACCCATTTTTT
AATAGACGGGCTAAATAATA

Downstream 100 bases:

>100_bases
GATATTTTTCTTAAGATTTAGTGTGTTAAAATAAATCAGCCTAAGGTAACTTAGGCTGATTTTTGCTTTCTGGACGATAA
ATATTTATTGTTTGTGGGAG

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MNDWSIDDARAGYNVTHWSQGFYGISDHGEVTVSPDPKNPDYKIGLNELAKDMVKAGVALPVLVRFPQILHHRVNSLCQA
FDQAIQKYEYQADYLLVYPIKVNQQQTVVEEILASQASKEVPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDNEYIR
LALIGEKLGHKVYIVLEKLSELKMVLAESKRLGVTPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILLVVEQLKQND
MLDSLQLLHFHLGSQIANIRDIRQGVSEAGRFYCELRALGASVNCFDVGGGLAVDYDGTRSQSNNSMNYGLTEYANNIVN
VLTDICNEYEQPMPRIISESGRYLTAHHAVLITDVIGTEAYQPEDIQPPAEESPQLLHNMWHSWSELSGRADQRALIEIY
HDSQSDLQEAHSLFALGQLSLAERAWAEQANLRVCHEVQGLLSAKNRYHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
DQVFPVLPLSGLDKAPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPAWSADSPYLIGFFLVGAYQEILGDMHNLFGD
TNSAVVRIEDNGVTNIESVLAGDTVADVLRYVNLDAVAFMRTYEELVNLHIAEDERAQILEELQVGLKGYTYLEDFS

Sequences:

>Translated_637_residues
MNDWSIDDARAGYNVTHWSQGFYGISDHGEVTVSPDPKNPDYKIGLNELAKDMVKAGVALPVLVRFPQILHHRVNSLCQA
FDQAIQKYEYQADYLLVYPIKVNQQQTVVEEILASQASKEVPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDNEYIR
LALIGEKLGHKVYIVLEKLSELKMVLAESKRLGVTPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILLVVEQLKQND
MLDSLQLLHFHLGSQIANIRDIRQGVSEAGRFYCELRALGASVNCFDVGGGLAVDYDGTRSQSNNSMNYGLTEYANNIVN
VLTDICNEYEQPMPRIISESGRYLTAHHAVLITDVIGTEAYQPEDIQPPAEESPQLLHNMWHSWSELSGRADQRALIEIY
HDSQSDLQEAHSLFALGQLSLAERAWAEQANLRVCHEVQGLLSAKNRYHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
DQVFPVLPLSGLDKAPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPAWSADSPYLIGFFLVGAYQEILGDMHNLFGD
TNSAVVRIEDNGVTNIESVLAGDTVADVLRYVNLDAVAFMRTYEELVNLHIAEDERAQILEELQVGLKGYTYLEDFS
>Mature_637_residues
MNDWSIDDARAGYNVTHWSQGFYGISDHGEVTVSPDPKNPDYKIGLNELAKDMVKAGVALPVLVRFPQILHHRVNSLCQA
FDQAIQKYEYQADYLLVYPIKVNQQQTVVEEILASQASKEVPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDNEYIR
LALIGEKLGHKVYIVLEKLSELKMVLAESKRLGVTPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILLVVEQLKQND
MLDSLQLLHFHLGSQIANIRDIRQGVSEAGRFYCELRALGASVNCFDVGGGLAVDYDGTRSQSNNSMNYGLTEYANNIVN
VLTDICNEYEQPMPRIISESGRYLTAHHAVLITDVIGTEAYQPEDIQPPAEESPQLLHNMWHSWSELSGRADQRALIEIY
HDSQSDLQEAHSLFALGQLSLAERAWAEQANLRVCHEVQGLLSAKNRYHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
DQVFPVLPLSGLDKAPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPAWSADSPYLIGFFLVGAYQEILGDMHNLFGD
TNSAVVRIEDNGVTNIESVLAGDTVADVLRYVNLDAVAFMRTYEELVNLHIAEDERAQILEELQVGLKGYTYLEDFS

Specific function: Catalyzes the biosynthesis of agmatine from arginine

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily

Homologues:

Organism=Escherichia coli, GI1789307, Length=624, Percent_Identity=56.8910256410256, Blast_Score=731, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEA_SHEB2 (B8EAI2)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002358434.1
- ProteinModelPortal:   B8EAI2
- GeneID:   7087053
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_2517
- HOGENOM:   HBG321436
- OMA:   TCDSDGE
- ProtClustDB:   PRK05354
- HAMAP:   MF_01417
- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR000183
- Gene3D:   G3DSA:2.40.37.10
- PANTHER:   PTHR11482:SF3
- PIRSF:   PIRSF001336
- PRINTS:   PR01180
- PRINTS:   PR01179
- TIGRFAMs:   TIGR01273

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC

EC number: =4.1.1.19

Molecular weight: Translated: 70895; Mature: 70895

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00878 ODR_DC_2_1; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDWSIDDARAGYNVTHWSQGFYGISDHGEVTVSPDPKNPDYKIGLNELAKDMVKAGVAL
CCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCEECHHHHHHHHHHCCCHH
PVLVRFPQILHHRVNSLCQAFDQAIQKYEYQADYLLVYPIKVNQQQTVVEEILASQASKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
VPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDNEYIRLALIGEKLGHKVYIVLEKLS
HHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECHHHCCEEEHHHHHHH
ELKMVLAESKRLGVTPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILLVVEQLKQND
HHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEECCCCCCCHHCHHHHHHHHHHHHHHHCC
MLDSLQLLHFHLGSQIANIRDIRQGVSEAGRFYCELRALGASVNCFDVGGGLAVDYDGTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCC
SQSNNSMNYGLTEYANNIVNVLTDICNEYEQPMPRIISESGRYLTAHHAVLITDVIGTEA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEECHHEEEEHHHCCCC
YQPEDIQPPAEESPQLLHNMWHSWSELSGRADQRALIEIYHDSQSDLQEAHSLFALGQLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEHEECCCHHHHHHHHHHHHHHHHH
LAERAWAEQANLRVCHEVQGLLSAKNRYHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DQVFPVLPLSGLDKAPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPAWSADSPYLIG
HHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHCCCCCCCCEECCCCCCCCCCCHHHH
FFLVGAYQEILGDMHNLFGDTNSAVVRIEDNGVTNIESVLAGDTVADVLRYVNLDAVAFM
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHCHHHHHHH
RTYEELVNLHIAEDERAQILEELQVGLKGYTYLEDFS
HHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNDWSIDDARAGYNVTHWSQGFYGISDHGEVTVSPDPKNPDYKIGLNELAKDMVKAGVAL
CCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCEECHHHHHHHHHHCCCHH
PVLVRFPQILHHRVNSLCQAFDQAIQKYEYQADYLLVYPIKVNQQQTVVEEILASQASKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
VPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDNEYIRLALIGEKLGHKVYIVLEKLS
HHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECHHHCCEEEHHHHHHH
ELKMVLAESKRLGVTPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILLVVEQLKQND
HHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEECCCCCCCHHCHHHHHHHHHHHHHHHCC
MLDSLQLLHFHLGSQIANIRDIRQGVSEAGRFYCELRALGASVNCFDVGGGLAVDYDGTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCC
SQSNNSMNYGLTEYANNIVNVLTDICNEYEQPMPRIISESGRYLTAHHAVLITDVIGTEA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEECHHEEEEHHHCCCC
YQPEDIQPPAEESPQLLHNMWHSWSELSGRADQRALIEIYHDSQSDLQEAHSLFALGQLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEHEECCCHHHHHHHHHHHHHHHHH
LAERAWAEQANLRVCHEVQGLLSAKNRYHRPIIDELNEKLADKFFVNFSLFQSLPDAWGI
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DQVFPVLPLSGLDKAPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPAWSADSPYLIG
HHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHCCCCCCCCEECCCCCCCCCCCHHHH
FFLVGAYQEILGDMHNLFGDTNSAVVRIEDNGVTNIESVLAGDTVADVLRYVNLDAVAFM
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHCHHHHHHH
RTYEELVNLHIAEDERAQILEELQVGLKGYTYLEDFS
HHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA