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The map label for this gene is pgcA [H]

Identifier: 126173795

GI number: 126173795

Start: 1819042

End: 1820763

Strand: Direct

Name: pgcA [H]

Synonym: Sbal_1561

Alternate gene names: 126173795

Gene position: 1819042-1820763 (Clockwise)

Preceding gene: 126173794

Following gene: 126173796

Centisome position: 35.48

GC content: 51.8

Gene sequence:

>1722_bases
ATGAATACCCATCTGCAGTTACAGGTAAACCATTGGCTTGAAAATGATCCTGACCCTCGCACTCAAACCCAATTACAAAC
CCTAATTGATAACGGCAGTGAAGCCGAACTCGCGGCGCGCTTTGCCGGTCGCTTAGAGTTTGGTACCGCAGGATTACGCG
GTGTGGTCGGCGCAGGACCCATGGGGATGAACCGTCTGGTGATCCGTCAAACCTCGGCAGGCCTTGGTGCTTATCTACTT
GATCAGATTAAAGATGCCGCCGAGCGTGGTGTGGTGATTGGTTACGATGGTCGCCACGACTCATTCAATTTTGCCCATGA
TGCGGCGAGCGTACTGACCGCTATGGGCATTAAGGTGCGCTTAACGTCTAAAGTGGCGCCGACACCGCTGGTGGCCTTTG
GGGTGAAGCATTTTAATGCGGCAGCAGGCATTGTAGTGACCGCGAGTCATAACCCGCCGCAATACAATGGCTATAAAGTC
TATTGGGAGAATGGCGCGCAGATTATTCCGCCCCATGATTCTGGTATTGCCGCGCAAATTGAGCGCGCCGCGAATCAAGC
GATTCCGTTTTTAGAACATGATGAGGCGGTAAAACAAGGTAAGTTGACACTCCTGCAGGACGATTTTTACCAAAGCTATC
GCCATGGCGTGCAGCACGCTGAGGTGCTGCAAAACCATACGGCTCCAGAAAAGGTCAGTTTAGCCTATACCGCCATGCAC
GGCGTGGGAGCTGAAATGGCTGAAACCGTATTGAAAGATGCGGGTTTCACCCAAGTGTATTCGGTAGCCTCCCAGCGCGA
ACCCGATGGCGATTTCCCGACGGTGAACTTCCCCAATCCGGAAGAAAAGGGCGCGATGGATTTAGTGATCGCCGAGGCGA
AAAAACACGGCGCTATGCTCGCCTGTGCCAACGATCCCGATGCCGACCGTTTTGCGGTCGCAGTGCGCCGTGATGATGGC
GAATACCAGATGCTAACGGGCGATCAAGTCGGTGTGCTCTTTGGGCATTACTTGTTATCTCACGCTAAAGATAATCAGCG
ACTTACGGGCACCACGATAGTGTCATCGAGTCTGTTATCTAAAATTGCTCAAGGGTTTGGCACGCAAAGCTTTACCACGC
TCACCGGCTTTAAGTGGCTGATGAATGTGGGTATCGCGAAAACGTCCCCTGAGGATCAATTCCTGTTTGCCTATGAAGAA
GCCCTTGGTTACACAGTTGGCAGCATGGTGTGGGATAAAGATGGCTTGTCGGCGCTGGTGGCATTTGCCCAATTAACTGC
CGAGCTGGTGGCGAAGGGGCAAACGATTTGGGACAGACTCGAGCAAATTTACCGTGAGCATGGCTTCCATCTCAATGCAC
AGGTGAGTATTGCACTAAAACCTGACACGCCTAATATTGGCGCCTATTTACGCGAACATCCCCCCGTGAAGATTGGTGAG
CATGACGTGCTCTCAACCGATGATTTAAAAGCCCTTGAGCGTCGTTTTGCCGATGGTAGCGTTGAGAAAATCGACTTGCC
ACCGAGTGATGTATTGACCTATTGCTTAGCGGGTGGCGCTCGGGTGATCGTTAGGCCATCTGGTACTGAACCTAAAATTA
AGTGCTACTACGAAGTGGTCGAAACTATGGTCGATACGGATACCTTAGCCAGTGCCCAAGCGAGAGCGAGCAAAGCCATG
GATGATTTTATTCAGGCGCACCAAGCCAGTTTGCCAAAGTAA

Upstream 100 bases:

>100_bases
AAATTAAGCCTCAGCTCATTTTGAAATTAATGCAAATTAGCTTGTTCTTCGCCGCTGTTTTTCCTAATGTGATTGCAAAT
GATTTTCAATGAGGCGTGTT

Downstream 100 bases:

>100_bases
CGCTTTTAACTGCTAAGCCAAAAACCTCAACATTCACTTTTATTAAAAGGCTACTGACATCATGCTGTCAGTAGCCTTGT
TTTATTCTTGTTGTCGCCCG

Product: phosphoglucomutase/phosphomannomutase alpha/beta/subunit

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MNTHLQLQVNHWLENDPDPRTQTQLQTLIDNGSEAELAARFAGRLEFGTAGLRGVVGAGPMGMNRLVIRQTSAGLGAYLL
DQIKDAAERGVVIGYDGRHDSFNFAHDAASVLTAMGIKVRLTSKVAPTPLVAFGVKHFNAAAGIVVTASHNPPQYNGYKV
YWENGAQIIPPHDSGIAAQIERAANQAIPFLEHDEAVKQGKLTLLQDDFYQSYRHGVQHAEVLQNHTAPEKVSLAYTAMH
GVGAEMAETVLKDAGFTQVYSVASQREPDGDFPTVNFPNPEEKGAMDLVIAEAKKHGAMLACANDPDADRFAVAVRRDDG
EYQMLTGDQVGVLFGHYLLSHAKDNQRLTGTTIVSSSLLSKIAQGFGTQSFTTLTGFKWLMNVGIAKTSPEDQFLFAYEE
ALGYTVGSMVWDKDGLSALVAFAQLTAELVAKGQTIWDRLEQIYREHGFHLNAQVSIALKPDTPNIGAYLREHPPVKIGE
HDVLSTDDLKALERRFADGSVEKIDLPPSDVLTYCLAGGARVIVRPSGTEPKIKCYYEVVETMVDTDTLASAQARASKAM
DDFIQAHQASLPK

Sequences:

>Translated_573_residues
MNTHLQLQVNHWLENDPDPRTQTQLQTLIDNGSEAELAARFAGRLEFGTAGLRGVVGAGPMGMNRLVIRQTSAGLGAYLL
DQIKDAAERGVVIGYDGRHDSFNFAHDAASVLTAMGIKVRLTSKVAPTPLVAFGVKHFNAAAGIVVTASHNPPQYNGYKV
YWENGAQIIPPHDSGIAAQIERAANQAIPFLEHDEAVKQGKLTLLQDDFYQSYRHGVQHAEVLQNHTAPEKVSLAYTAMH
GVGAEMAETVLKDAGFTQVYSVASQREPDGDFPTVNFPNPEEKGAMDLVIAEAKKHGAMLACANDPDADRFAVAVRRDDG
EYQMLTGDQVGVLFGHYLLSHAKDNQRLTGTTIVSSSLLSKIAQGFGTQSFTTLTGFKWLMNVGIAKTSPEDQFLFAYEE
ALGYTVGSMVWDKDGLSALVAFAQLTAELVAKGQTIWDRLEQIYREHGFHLNAQVSIALKPDTPNIGAYLREHPPVKIGE
HDVLSTDDLKALERRFADGSVEKIDLPPSDVLTYCLAGGARVIVRPSGTEPKIKCYYEVVETMVDTDTLASAQARASKAM
DDFIQAHQASLPK
>Mature_573_residues
MNTHLQLQVNHWLENDPDPRTQTQLQTLIDNGSEAELAARFAGRLEFGTAGLRGVVGAGPMGMNRLVIRQTSAGLGAYLL
DQIKDAAERGVVIGYDGRHDSFNFAHDAASVLTAMGIKVRLTSKVAPTPLVAFGVKHFNAAAGIVVTASHNPPQYNGYKV
YWENGAQIIPPHDSGIAAQIERAANQAIPFLEHDEAVKQGKLTLLQDDFYQSYRHGVQHAEVLQNHTAPEKVSLAYTAMH
GVGAEMAETVLKDAGFTQVYSVASQREPDGDFPTVNFPNPEEKGAMDLVIAEAKKHGAMLACANDPDADRFAVAVRRDDG
EYQMLTGDQVGVLFGHYLLSHAKDNQRLTGTTIVSSSLLSKIAQGFGTQSFTTLTGFKWLMNVGIAKTSPEDQFLFAYEE
ALGYTVGSMVWDKDGLSALVAFAQLTAELVAKGQTIWDRLEQIYREHGFHLNAQVSIALKPDTPNIGAYLREHPPVKIGE
HDVLSTDDLKALERRFADGSVEKIDLPPSDVLTYCLAGGARVIVRPSGTEPKIKCYYEVVETMVDTDTLASAQARASKAM
DDFIQAHQASLPK

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=578, Percent_Identity=35.9861591695502, Blast_Score=333, Evalue=2e-91,
Organism=Homo sapiens, GI31377548, Length=594, Percent_Identity=32.996632996633, Blast_Score=301, Evalue=1e-81,
Organism=Escherichia coli, GI1789566, Length=292, Percent_Identity=26.027397260274, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71993870, Length=554, Percent_Identity=35.7400722021661, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI71993878, Length=318, Percent_Identity=36.1635220125786, Blast_Score=195, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6323934, Length=578, Percent_Identity=35.4671280276817, Blast_Score=280, Evalue=3e-76,
Organism=Drosophila melanogaster, GI20129809, Length=572, Percent_Identity=36.5384615384615, Blast_Score=320, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24651977, Length=517, Percent_Identity=36.9439071566731, Blast_Score=301, Evalue=7e-82,
Organism=Drosophila melanogaster, GI24653722, Length=562, Percent_Identity=31.3167259786477, Blast_Score=257, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 62345; Mature: 62345

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTHLQLQVNHWLENDPDPRTQTQLQTLIDNGSEAELAARFAGRLEFGTAGLRGVVGAGP
CCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
MGMNRLVIRQTSAGLGAYLLDQIKDAAERGVVIGYDGRHDSFNFAHDAASVLTAMGIKVR
CCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHCCEEEE
LTSKVAPTPLVAFGVKHFNAAAGIVVTASHNPPQYNGYKVYWENGAQIIPPHDSGIAAQI
EECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCEEECCCCCCHHHHH
ERAANQAIPFLEHDEAVKQGKLTLLQDDFYQSYRHGVQHAEVLQNHTAPEKVSLAYTAMH
HHHHHHCCCCCCCHHHHHCCCEEEEHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEEHHHH
GVGAEMAETVLKDAGFTQVYSVASQREPDGDFPTVNFPNPEEKGAMDLVIAEAKKHGAML
CCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCEE
ACANDPDADRFAVAVRRDDGEYQMLTGDQVGVLFGHYLLSHAKDNQRLTGTTIVSSSLLS
EECCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
KIAQGFGTQSFTTLTGFKWLMNVGIAKTSPEDQFLFAYEEALGYTVGSMVWDKDGLSALV
HHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHEECCCHHHHHH
AFAQLTAELVAKGQTIWDRLEQIYREHGFHLNAQVSIALKPDTPNIGAYLREHPPVKIGE
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCHHHHCCCCCCCCC
HDVLSTDDLKALERRFADGSVEKIDLPPSDVLTYCLAGGARVIVRPSGTEPKIKCYYEVV
CCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHH
ETMVDTDTLASAQARASKAMDDFIQAHQASLPK
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTHLQLQVNHWLENDPDPRTQTQLQTLIDNGSEAELAARFAGRLEFGTAGLRGVVGAGP
CCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
MGMNRLVIRQTSAGLGAYLLDQIKDAAERGVVIGYDGRHDSFNFAHDAASVLTAMGIKVR
CCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHCCEEEE
LTSKVAPTPLVAFGVKHFNAAAGIVVTASHNPPQYNGYKVYWENGAQIIPPHDSGIAAQI
EECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCEEECCCCCCHHHHH
ERAANQAIPFLEHDEAVKQGKLTLLQDDFYQSYRHGVQHAEVLQNHTAPEKVSLAYTAMH
HHHHHHCCCCCCCHHHHHCCCEEEEHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEEHHHH
GVGAEMAETVLKDAGFTQVYSVASQREPDGDFPTVNFPNPEEKGAMDLVIAEAKKHGAML
CCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCEE
ACANDPDADRFAVAVRRDDGEYQMLTGDQVGVLFGHYLLSHAKDNQRLTGTTIVSSSLLS
EECCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
KIAQGFGTQSFTTLTGFKWLMNVGIAKTSPEDQFLFAYEEALGYTVGSMVWDKDGLSALV
HHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHEECCCHHHHHH
AFAQLTAELVAKGQTIWDRLEQIYREHGFHLNAQVSIALKPDTPNIGAYLREHPPVKIGE
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCHHHHCCCCCCCCC
HDVLSTDDLKALERRFADGSVEKIDLPPSDVLTYCLAGGARVIVRPSGTEPKIKCYYEVV
CCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHH
ETMVDTDTLASAQARASKAMDDFIQAHQASLPK
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]