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The map label for this gene is cat2 [H]

Identifier: 126173762

GI number: 126173762

Start: 1775300

End: 1776586

Strand: Direct

Name: cat2 [H]

Synonym: Sbal_1526

Alternate gene names: 126173762

Gene position: 1775300-1776586 (Clockwise)

Preceding gene: 126173761

Following gene: 126173763

Centisome position: 34.62

GC content: 51.83

Gene sequence:

>1287_bases
ATGCCTGCAATCATTTGTCATAGCGCGCTCGAAGCCGTTGCATTAATTCAAAGTGGCGAGACGCTGTGGACGCATTCCAT
GGGCGCCACGCCGCGGATTTTACTCGATGCGTTGGCGCAGCACGCACTCACTAAAGACAATCTCACCTTATTACAGTTAC
ATACCGAAGGCGCTGAATCCTTAAGCCATCCGAGTTTACAGGGGCATTTACGTCATCGATGTTTTTTCGGTGGTCTGCCG
ACGCGGGCATTATTGCAAAGTGGTGATGCGGATTACGTGCCGATTTTCCTGTCTGAAGTGCCTAAGTTATTTCGCTCCGG
CGAGCAAAAAATTGATACTGCGATTATCCAAGTCTCGCCGCCCGATAAGCACGGCATGTGTTCCTTAGGGATCTCGGTCG
AAGCCACGCTTGCGGCCTGCCAAGTGGCGGGTAAGATCATCGCCCATATTAATCCTCAAATGCCACGCACCCACGGCGAT
GGATTTATCCATATCGACCGCTTTGCCGCTGTGTATGAAGAAAGTGCGGCCTTGCCGATCCATTCTTTTGGTACGGGCGA
TGCCGTGAGTCTGGCGATTGGCAAAAATGTCGCCCAATTGGTACGCGATGGTGATTGCCTGCAGATGGGCATAGGTGCAA
TCCCCGATGCTGTTTTATCTTGCTTAACCGACCATAAGGATTTGGGCGTTCACACTGAGCTATTTTCTGACGGCATATTA
CAACTGGTTGAAAAGGGCGTGATTAACAACAGCAAGAAGCGGTTTTATCCGGGGAAATTAGTCACAGGTTTTGCCCTGGG
TAGTCAAAAGTTATACGACTATGTTGATGATAATCCTGCGGTTATCTTTATGGACATAGAGCAAGTCAACGACACGTCCA
TTATCCGTAAAAACCCCAATGTAATGGCAATTAACTCGGCGCTGCAGGTCGACCTTTCTGGCCAAGTGTGCGCCGATTCG
ATTGGCACTAAAATCTATTCCGGCGTCGGCGGCCAGATGGATTTTATCCGCGGCGCAGGCTTATCCGAAGGCGGTCGCTC
TGTGATTGCGTTGCCCAGCACGGCTGCAGGCGGCACGATTTCCCGCATCGCCAGTGTGTTATCACCCGGCGCGGGTGTCG
TTACCACTCGGGCTCATGTGCATTATATTGTGACCGAATACGGCGCCGCCAATCTACGCGGTCGTTCACTGCGCGAACGG
GCACAAGCGTTGATCGCCATCGCTCACCCAGAATTTAGGGAGCAACTGAGTCGTGATGCCTTCGATGTTTGGGGCTTAAG
ACTGTAG

Upstream 100 bases:

>100_bases
GTCGCGCTAAGCCATTGAAATCGATATTGCTTAATTAGGATATCCCTTACACTACTGCTAGGGCCATTGCCGCCATCATG
CTTAGGGAAGGGAATTCATT

Downstream 100 bases:

>100_bases
TTTTTAGGTGTGATCCCTCGTTCTGATCTGTCGCTCAGTCTTCATTGATGGCAAGCATAAACATAAAGAGAGGTAGGCTG
GGCGTACTAGATCCCTCGCG

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MPAIICHSALEAVALIQSGETLWTHSMGATPRILLDALAQHALTKDNLTLLQLHTEGAESLSHPSLQGHLRHRCFFGGLP
TRALLQSGDADYVPIFLSEVPKLFRSGEQKIDTAIIQVSPPDKHGMCSLGISVEATLAACQVAGKIIAHINPQMPRTHGD
GFIHIDRFAAVYEESAALPIHSFGTGDAVSLAIGKNVAQLVRDGDCLQMGIGAIPDAVLSCLTDHKDLGVHTELFSDGIL
QLVEKGVINNSKKRFYPGKLVTGFALGSQKLYDYVDDNPAVIFMDIEQVNDTSIIRKNPNVMAINSALQVDLSGQVCADS
IGTKIYSGVGGQMDFIRGAGLSEGGRSVIALPSTAAGGTISRIASVLSPGAGVVTTRAHVHYIVTEYGAANLRGRSLRER
AQALIAIAHPEFREQLSRDAFDVWGLRL

Sequences:

>Translated_428_residues
MPAIICHSALEAVALIQSGETLWTHSMGATPRILLDALAQHALTKDNLTLLQLHTEGAESLSHPSLQGHLRHRCFFGGLP
TRALLQSGDADYVPIFLSEVPKLFRSGEQKIDTAIIQVSPPDKHGMCSLGISVEATLAACQVAGKIIAHINPQMPRTHGD
GFIHIDRFAAVYEESAALPIHSFGTGDAVSLAIGKNVAQLVRDGDCLQMGIGAIPDAVLSCLTDHKDLGVHTELFSDGIL
QLVEKGVINNSKKRFYPGKLVTGFALGSQKLYDYVDDNPAVIFMDIEQVNDTSIIRKNPNVMAINSALQVDLSGQVCADS
IGTKIYSGVGGQMDFIRGAGLSEGGRSVIALPSTAAGGTISRIASVLSPGAGVVTTRAHVHYIVTEYGAANLRGRSLRER
AQALIAIAHPEFREQLSRDAFDVWGLRL
>Mature_427_residues
PAIICHSALEAVALIQSGETLWTHSMGATPRILLDALAQHALTKDNLTLLQLHTEGAESLSHPSLQGHLRHRCFFGGLPT
RALLQSGDADYVPIFLSEVPKLFRSGEQKIDTAIIQVSPPDKHGMCSLGISVEATLAACQVAGKIIAHINPQMPRTHGDG
FIHIDRFAAVYEESAALPIHSFGTGDAVSLAIGKNVAQLVRDGDCLQMGIGAIPDAVLSCLTDHKDLGVHTELFSDGILQ
LVEKGVINNSKKRFYPGKLVTGFALGSQKLYDYVDDNPAVIFMDIEQVNDTSIIRKNPNVMAINSALQVDLSGQVCADSI
GTKIYSGVGGQMDFIRGAGLSEGGRSVIALPSTAAGGTISRIASVLSPGAGVVTTRAHVHYIVTEYGAANLRGRSLRERA
QALIAIAHPEFREQLSRDAFDVWGLRL

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=217, Percent_Identity=29.4930875576037, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32563853, Length=422, Percent_Identity=48.3412322274881, Blast_Score=397, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17538151, Length=425, Percent_Identity=43.2941176470588, Blast_Score=350, Evalue=6e-97,
Organism=Saccharomyces cerevisiae, GI6319456, Length=487, Percent_Identity=22.7926078028747, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358615, Length=417, Percent_Identity=48.4412470023981, Blast_Score=396, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 45706; Mature: 45575

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAIICHSALEAVALIQSGETLWTHSMGATPRILLDALAQHALTKDNLTLLQLHTEGAES
CCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCHHH
LSHPSLQGHLRHRCFFGGLPTRALLQSGDADYVPIFLSEVPKLFRSGEQKIDTAIIQVSP
HCCCCHHHHHHHHEEECCCCHHHHHHCCCCCEEHHHHHHHHHHHHCCCCEEEEEEEEECC
PDKHGMCSLGISVEATLAACQVAGKIIAHINPQMPRTHGDGFIHIDRFAAVYEESAALPI
CCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCE
HSFGTGDAVSLAIGKNVAQLVRDGDCLQMGIGAIPDAVLSCLTDHKDLGVHTELFSDGIL
ECCCCCCEEEEHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHH
QLVEKGVINNSKKRFYPGKLVTGFALGSQKLYDYVDDNPAVIFMDIEQVNDTSIIRKNPN
HHHHHHHCCCCCCEECCCCEEEEEECCCHHHHHHCCCCCEEEEEEECCCCCCEEEECCCC
VMAINSALQVDLSGQVCADSIGTKIYSGVGGQMDFIRGAGLSEGGRSVIALPSTAAGGTI
EEEECCEEEEECCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCHH
SRIASVLSPGAGVVTTRAHVHYIVTEYGAANLRGRSLRERAQALIAIAHPEFREQLSRDA
HHHHHHHCCCCCEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHEEEECCHHHHHHHCCCH
FDVWGLRL
HHHCCCCC
>Mature Secondary Structure 
PAIICHSALEAVALIQSGETLWTHSMGATPRILLDALAQHALTKDNLTLLQLHTEGAES
CCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCHHH
LSHPSLQGHLRHRCFFGGLPTRALLQSGDADYVPIFLSEVPKLFRSGEQKIDTAIIQVSP
HCCCCHHHHHHHHEEECCCCHHHHHHCCCCCEEHHHHHHHHHHHHCCCCEEEEEEEEECC
PDKHGMCSLGISVEATLAACQVAGKIIAHINPQMPRTHGDGFIHIDRFAAVYEESAALPI
CCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCE
HSFGTGDAVSLAIGKNVAQLVRDGDCLQMGIGAIPDAVLSCLTDHKDLGVHTELFSDGIL
ECCCCCCEEEEHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHH
QLVEKGVINNSKKRFYPGKLVTGFALGSQKLYDYVDDNPAVIFMDIEQVNDTSIIRKNPN
HHHHHHHCCCCCCEECCCCEEEEEECCCHHHHHHCCCCCEEEEEEECCCCCCEEEECCCC
VMAINSALQVDLSGQVCADSIGTKIYSGVGGQMDFIRGAGLSEGGRSVIALPSTAAGGTI
EEEECCEEEEECCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCHH
SRIASVLSPGAGVVTTRAHVHYIVTEYGAANLRGRSLRERAQALIAIAHPEFREQLSRDA
HHHHHHHCCCCCEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHEEEECCHHHHHHHCCCH
FDVWGLRL
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]