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The map label for this gene is lepB [H]

Identifier: 126173761

GI number: 126173761

Start: 1774244

End: 1775020

Strand: Direct

Name: lepB [H]

Synonym: Sbal_1525

Alternate gene names: 126173761

Gene position: 1774244-1775020 (Clockwise)

Preceding gene: 126173760

Following gene: 126173762

Centisome position: 34.6

GC content: 42.99

Gene sequence:

>777_bases
ATGGCTTGGCTTCAACATATTTACCTCTCTTGGTTATTTATTGTTATTTGTCCCATTCACGGGTTTATGATCGCCCGTCG
TTACGATATTACTCAACCCCGCCGCTGGTATGCTCGCTGGTGGATAGTGTTAGCGAGTTACGCTTTGATGATGTTACCGC
TGATTGTGTTACGAGGTTTTTTCTTTGAGCCTTTTAGTATTCCGGCCTCTTCCATGAAGCCGACGTTAGCGCCCGGCAAT
CATGTGTTGGTGAGCAAGTATGGTTTTGGTAACTATCGATATTTAGGTTTTCAACTGGCTAAGTCGACGCCATCGGTAAC
ACCCGCAAGAGGGGATATATTGGTATTTCAATACCCTGCAAACCCGACGATTGACTATGTAAAACGTGTAATTGGTCTAC
CCGGCGATAGGATTATCTATCGCGACAAAACCATTTTTGTGCAGAAAGCCTGCGATGTATCGAGGGAAGCCTGTGCAGGA
TTGGGCTCTCAATACGATCTTATCGATAAAACCTTATTACCCGAGTTCAGTACTGAGACTCAAGCCGTTTACCAAGAGTC
GCTGGATGATATTCACTATCAGGTATTATTACTCCGCCATCAGAAAGAACTGGTTGATCGCTATTATGTGCAAGAAAACA
CATTAAGGGGTGAATGGTTAGTTCCCGCTGGTCAGTATTTCGTCTTGGGTGATAACAGAGACAATAGCTTAGATAGTCGA
TATTTTGGGTTTATTCCTCAAGACTTGATTATTGGTAAAGTGATATATATTTGGTAA

Upstream 100 bases:

>100_bases
TCAATTTAAATATTTTATTCGATATTTTATTGGTGCGCTGATTATCGCGGCCGTGGATGTATTTTTACACTCCAATTACT
TCCCATTTAAATCGGGGAAT

Downstream 100 bases:

>100_bases
GGCTGAGTGCTGATGGGGATAACCTAATACGGGCTTATTGGTGTTATCCCTAATCAAACTGTTGCAAAGCATTTTAGCCA
GAGGCTTTATTACCCTCTAG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MAWLQHIYLSWLFIVICPIHGFMIARRYDITQPRRWYARWWIVLASYALMMLPLIVLRGFFFEPFSIPASSMKPTLAPGN
HVLVSKYGFGNYRYLGFQLAKSTPSVTPARGDILVFQYPANPTIDYVKRVIGLPGDRIIYRDKTIFVQKACDVSREACAG
LGSQYDLIDKTLLPEFSTETQAVYQESLDDIHYQVLLLRHQKELVDRYYVQENTLRGEWLVPAGQYFVLGDNRDNSLDSR
YFGFIPQDLIIGKVIYIW

Sequences:

>Translated_258_residues
MAWLQHIYLSWLFIVICPIHGFMIARRYDITQPRRWYARWWIVLASYALMMLPLIVLRGFFFEPFSIPASSMKPTLAPGN
HVLVSKYGFGNYRYLGFQLAKSTPSVTPARGDILVFQYPANPTIDYVKRVIGLPGDRIIYRDKTIFVQKACDVSREACAG
LGSQYDLIDKTLLPEFSTETQAVYQESLDDIHYQVLLLRHQKELVDRYYVQENTLRGEWLVPAGQYFVLGDNRDNSLDSR
YFGFIPQDLIIGKVIYIW
>Mature_257_residues
AWLQHIYLSWLFIVICPIHGFMIARRYDITQPRRWYARWWIVLASYALMMLPLIVLRGFFFEPFSIPASSMKPTLAPGNH
VLVSKYGFGNYRYLGFQLAKSTPSVTPARGDILVFQYPANPTIDYVKRVIGLPGDRIIYRDKTIFVQKACDVSREACAGL
GSQYDLIDKTLLPEFSTETQAVYQESLDDIHYQVLLLRHQKELVDRYYVQENTLRGEWLVPAGQYFVLGDNRDNSLDSRY
FGFIPQDLIIGKVIYIW

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=244, Percent_Identity=32.7868852459016, Blast_Score=147, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR019533
- InterPro:   IPR019766 [H]

Pfam domain/function: PF00717 Peptidase_S24; PF10502 Peptidase_S26 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 29997; Mature: 29866

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWLQHIYLSWLFIVICPIHGFMIARRYDITQPRRWYARWWIVLASYALMMLPLIVLRGF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFEPFSIPASSMKPTLAPGNHVLVSKYGFGNYRYLGFQLAKSTPSVTPARGDILVFQYPA
CCCCCCCCHHCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCEEEEEECC
NPTIDYVKRVIGLPGDRIIYRDKTIFVQKACDVSREACAGLGSQYDLIDKTLLPEFSTET
CCHHHHHHHHHCCCCCEEEEECCEEEEEHHHCCCHHHHHCCCCCHHHHHHHHCCCCCCHH
QAVYQESLDDIHYQVLLLRHQKELVDRYYVQENTLRGEWLVPAGQYFVLGDNRDNSLDSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCCCCH
YFGFIPQDLIIGKVIYIW
HCCCCCHHHHHCEEEEEC
>Mature Secondary Structure 
AWLQHIYLSWLFIVICPIHGFMIARRYDITQPRRWYARWWIVLASYALMMLPLIVLRGF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFEPFSIPASSMKPTLAPGNHVLVSKYGFGNYRYLGFQLAKSTPSVTPARGDILVFQYPA
CCCCCCCCHHCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCEEEEEECC
NPTIDYVKRVIGLPGDRIIYRDKTIFVQKACDVSREACAGLGSQYDLIDKTLLPEFSTET
CCHHHHHHHHHCCCCCEEEEECCEEEEEHHHCCCHHHHHCCCCCHHHHHHHHCCCCCCHH
QAVYQESLDDIHYQVLLLRHQKELVDRYYVQENTLRGEWLVPAGQYFVLGDNRDNSLDSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCCCCH
YFGFIPQDLIIGKVIYIW
HCCCCCHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]