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The map label for this gene is uppS [H]

Identifier: 126173692

GI number: 126173692

Start: 1686085

End: 1686912

Strand: Direct

Name: uppS [H]

Synonym: Sbal_1454

Alternate gene names: 126173692

Gene position: 1686085-1686912 (Clockwise)

Preceding gene: 126173691

Following gene: 126173693

Centisome position: 32.88

GC content: 46.98

Gene sequence:

>828_bases
ATGTCATCCACAGTGGAACTTGATCCGCACCCTAGGACGAGTGAGAGTGATTTACACACTCAAACGACCTTGCCGGGACA
ATTACCCGAACTCGTGAAACAGTCGTTACCTAAGCATGTTGCCATTATCATGGATGGCAATGGGCGCTGGGCACAAACCC
AAGGTAAACCACGAGTGTTGGGACATAAGGCCGGTGTTAAGGCCGTTAGAAGAGCCGTAAGCACGGCAAGCCAATTGGGC
ATTGAATCGCTAACGTTATTTGCATTTTCTAGCGAGAATTGGCGAAGACCCGATAAAGAAGTCAGCTTGCTGATGGAATT
GTTTTTTACCGTATTACAGCGCGAAATTAAATTGCTGCATAAGAATCAGGTTAAGCTGAAGATTATTGGTGATATCAGCC
GTTTTTCGGCGCGATTACAGAAGCAAATTGCAGCTGCGCAAGATAAAACATCAGGCAATACTGGCTTGGTTCTGAATGTT
GCCGCTAACTATGGTGGCCGTTGGGACATACTTCAAGCAGCCCAAAAATTAGCGGAAAAGGTCGAAACTGGCGAAATGAC
CAGCAGTCAGTTCACCGAAGAAGCCTTAAGTGCACATTTGTGCATGCAAAATCAGAGTGAAGTTGATTTAATGATCCGCA
CGGGCGGGGACTGTCGCATCAGCAATTTTGTGCTGTGGCAGGCGGCCTATGCAGAATTGGTGTTTACTGACACCCTTTGG
CCTGATTTCGATGAACAGGCTTTTCATGAAGCGATTGCCATTTTTGCAAGTCGCCAGCGCCGCTTTGGTTTGACTGGAAG
TCAGATTGATGAGATGCGTGCATTGTAA

Upstream 100 bases:

>100_bases
GAGTTGATGGAAGTCTAATCTCAAGTTCGATAAGCTAGAGTTGATGCGCCGTGTAGGGGTATACTACACGGCGTTTGTCT
ATTTTAAAGGGCTGTATTAG

Downstream 100 bases:

>100_bases
AACCTCATGAGGGATTTTTTTTGCTAAAACAACGAATAATAACAGCAATTTGGTTAGTTCCATTAGTTTTGGGGGCGATA
TTTTTACTCCCTGCCAACTA

Product: undecaprenyl diphosphate synthase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSSTVELDPHPRTSESDLHTQTTLPGQLPELVKQSLPKHVAIIMDGNGRWAQTQGKPRVLGHKAGVKAVRRAVSTASQLG
IESLTLFAFSSENWRRPDKEVSLLMELFFTVLQREIKLLHKNQVKLKIIGDISRFSARLQKQIAAAQDKTSGNTGLVLNV
AANYGGRWDILQAAQKLAEKVETGEMTSSQFTEEALSAHLCMQNQSEVDLMIRTGGDCRISNFVLWQAAYAELVFTDTLW
PDFDEQAFHEAIAIFASRQRRFGLTGSQIDEMRAL

Sequences:

>Translated_275_residues
MSSTVELDPHPRTSESDLHTQTTLPGQLPELVKQSLPKHVAIIMDGNGRWAQTQGKPRVLGHKAGVKAVRRAVSTASQLG
IESLTLFAFSSENWRRPDKEVSLLMELFFTVLQREIKLLHKNQVKLKIIGDISRFSARLQKQIAAAQDKTSGNTGLVLNV
AANYGGRWDILQAAQKLAEKVETGEMTSSQFTEEALSAHLCMQNQSEVDLMIRTGGDCRISNFVLWQAAYAELVFTDTLW
PDFDEQAFHEAIAIFASRQRRFGLTGSQIDEMRAL
>Mature_274_residues
SSTVELDPHPRTSESDLHTQTTLPGQLPELVKQSLPKHVAIIMDGNGRWAQTQGKPRVLGHKAGVKAVRRAVSTASQLGI
ESLTLFAFSSENWRRPDKEVSLLMELFFTVLQREIKLLHKNQVKLKIIGDISRFSARLQKQIAAAQDKTSGNTGLVLNVA
ANYGGRWDILQAAQKLAEKVETGEMTSSQFTEEALSAHLCMQNQSEVDLMIRTGGDCRISNFVLWQAAYAELVFTDTLWP
DFDEQAFHEAIAIFASRQRRFGLTGSQIDEMRAL

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580738, Length=223, Percent_Identity=35.8744394618834, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI45580742, Length=223, Percent_Identity=35.8744394618834, Blast_Score=137, Evalue=8e-33,
Organism=Escherichia coli, GI1786371, Length=228, Percent_Identity=63.5964912280702, Blast_Score=310, Evalue=9e-86,
Organism=Caenorhabditis elegans, GI71993029, Length=215, Percent_Identity=33.0232558139535, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6319474, Length=216, Percent_Identity=34.2592592592593, Blast_Score=115, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6323748, Length=235, Percent_Identity=31.4893617021277, Blast_Score=112, Evalue=7e-26,
Organism=Drosophila melanogaster, GI18857969, Length=241, Percent_Identity=31.5352697095436, Blast_Score=124, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 30680; Mature: 30549

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS01066 UPP_SYNTHETASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTVELDPHPRTSESDLHTQTTLPGQLPELVKQSLPKHVAIIMDGNGRWAQTQGKPRVL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCEECCCCCCCCC
GHKAGVKAVRRAVSTASQLGIESLTLFAFSSENWRRPDKEVSLLMELFFTVLQREIKLLH
CCHHHHHHHHHHHHHHHHHCHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KNQVKLKIIGDISRFSARLQKQIAAAQDKTSGNTGLVLNVAANYGGRWDILQAAQKLAEK
CCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
VETGEMTSSQFTEEALSAHLCMQNQSEVDLMIRTGGDCRISNFVLWQAAYAELVFTDTLW
HHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHEECCCC
PDFDEQAFHEAIAIFASRQRRFGLTGSQIDEMRAL
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure 
SSTVELDPHPRTSESDLHTQTTLPGQLPELVKQSLPKHVAIIMDGNGRWAQTQGKPRVL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCEECCCCCCCCC
GHKAGVKAVRRAVSTASQLGIESLTLFAFSSENWRRPDKEVSLLMELFFTVLQREIKLLH
CCHHHHHHHHHHHHHHHHHCHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KNQVKLKIIGDISRFSARLQKQIAAAQDKTSGNTGLVLNVAANYGGRWDILQAAQKLAEK
CCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
VETGEMTSSQFTEEALSAHLCMQNQSEVDLMIRTGGDCRISNFVLWQAAYAELVFTDTLW
HHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHEECCCC
PDFDEQAFHEAIAIFASRQRRFGLTGSQIDEMRAL
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]