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The map label for this gene is frr

Identifier: 126173691

GI number: 126173691

Start: 1685445

End: 1686002

Strand: Direct

Name: frr

Synonym: Sbal_1453

Alternate gene names: 126173691

Gene position: 1685445-1686002 (Clockwise)

Preceding gene: 126173690

Following gene: 126173692

Centisome position: 32.87

GC content: 44.27

Gene sequence:

>558_bases
GTGATTGAGAACATTAAGAAAGATGCGCAAGAACGCATGGGTAAATGTGTAGACGCAACTAAAAACCAAATGGCAAAAGT
GCGTACAGGTCGTGCCCACCCAAGCCTGCTTGATTCAATTCAAGTGTCTTACTACGGTACTATGACACCACTGAACCAAG
TGGCTAACGTGGGTGTTGAAGACTCTCGCACTCTGTCTGTGACTGTATTCGATCGTAGTGCAATCCAAGCCGTTGAAAAA
GCCATTATGAGCTCTGATCTAGGTCTGAACCCTATGTCTGCAGGCGCGACATTACGTATTCCATTACCCGCGCTGACTGA
AGAACGTCGTAAAGACTTCATTAAAGTTGTGCGTAACGAAGCTGAAAACGGTCGTATCGCCATCCGTAACGTACGTCGTG
ATGCCATTTCTGAAGTGAAAAAACTTGAGAAAGCCAAAGCTTGTACTGAAGATGATGTTCGTCGCAGCGAAGAAGAAGTA
CAAAAGTTCACCGATGCTCACATTAAAAAGATTGATGAGATTTTAGCGGCCAAAGAAATTGAGTTGATGGAAGTCTAA

Upstream 100 bases:

>100_bases
GAACAAGCCTGGCGCTCTACGCCGCGTTATCATGGGTGAAGAAGAAGGCACGCTGATCAGAGCGAAAAAAGTTATTTAAT
GACCAAGAAGGACATTTAAC

Downstream 100 bases:

>100_bases
TCTCAAGTTCGATAAGCTAGAGTTGATGCGCCGTGTAGGGGTATACTACACGGCGTTTGTCTATTTTAAAGGGCTGTATT
AGATGTCATCCACAGTGGAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIENIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVEDSRTLSVTVFDRSAIQAVEK
AIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRNEAENGRIAIRNVRRDAISEVKKLEKAKACTEDDVRRSEEEV
QKFTDAHIKKIDEILAAKEIELMEV

Sequences:

>Translated_185_residues
MIENIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVEDSRTLSVTVFDRSAIQAVEK
AIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRNEAENGRIAIRNVRRDAISEVKKLEKAKACTEDDVRRSEEEV
QKFTDAHIKKIDEILAAKEIELMEV
>Mature_185_residues
MIENIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVEDSRTLSVTVFDRSAIQAVEK
AIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRNEAENGRIAIRNVRRDAISEVKKLEKAKACTEDDVRRSEEEV
QKFTDAHIKKIDEILAAKEIELMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=178, Percent_Identity=26.9662921348315, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI291042689, Length=149, Percent_Identity=27.5167785234899, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=65.7608695652174, Blast_Score=241, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=29.4797687861272, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_SHEB2 (B8E7R3)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002358808.1
- ProteinModelPortal:   B8E7R3
- SMR:   B8E7R3
- GeneID:   7089468
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_2899
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20698; Mature: 20698

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIENIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
DSRTLSVTVFDRSAIQAVEKAIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRNE
CCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCC
AENGRIAIRNVRRDAISEVKKLEKAKACTEDDVRRSEEEVQKFTDAHIKKIDEILAAKEI
CCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC
>Mature Secondary Structure
MIENIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
DSRTLSVTVFDRSAIQAVEKAIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRNE
CCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCC
AENGRIAIRNVRRDAISEVKKLEKAKACTEDDVRRSEEEVQKFTDAHIKKIDEILAAKEI
CCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA