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The map label for this gene is aqpZ [H]

Identifier: 126173406

GI number: 126173406

Start: 1346027

End: 1346722

Strand: Reverse

Name: aqpZ [H]

Synonym: Sbal_1167

Alternate gene names: 126173406

Gene position: 1346722-1346027 (Counterclockwise)

Preceding gene: 126173407

Following gene: 126173405

Centisome position: 26.27

GC content: 51.72

Gene sequence:

>696_bases
ATGAATATGTCACAAAAAATGGCGGCGGAATTTCTTGGCACCTTGTGGTTAGTCCTTGGAGGCTGTGGCAGTGCGGTACT
TGCCGCTGCATTTCCCGAGGTGGGCATAGGCTTACTCGGTGTCGCGTTCGCATTTGGCTTAACTGTTCTCACTATGGCCT
TTGCGATTGGCCATATTTCAGGTTGTCACCTTAACCCAGCGGTGTCATTCGGCCTTTGGGCTGGCGGACGTTTTCCAGCG
GCAGAATTATTGCCCTATATCATAGCCCAAGTCGCGGGCGGGATTGCAGGGGCGGGTATCTTGTATCTTATTGCTTCTGG
GGAGGAAGGATTTTCACTCGCCGGCGGATTTGCCTCTAACGGTTTTGGTGAGCACTCCCCTGGCGGTTACAGCATGCTGT
CGGTCATGATTTGTGAAGTTGTTATGACACTGTTTTTCTTAATCATTATTTTAGGTGCCACCGATGAACGCGCACCCAAA
GGGTTCGCCCCGATTGCGATAGGTCTAGGCTTAACCTTGATCCACCTTATCAGTATTCCAGTGTCCAATACTTCGGTGAA
TCCTGCGCGCAGTACAGGTCCTGCGTTGTTTGTCGGTGACTGGGCGGTATCGCAGCTCTGGTTATTCTGGGTAGCACCGA
TTGTCGGCGCGATTTTGGCAGGCTTTATCTATCGCTACTTCCGCGCGGCAGAATAA

Upstream 100 bases:

>100_bases
TTTGCTCACTCAGACAAAACCCGCCAATAGACAGGTAAATAAGGAATAAAGACGCACTCGTTAACAAACAAGTGTCTTTA
ACATAATAGGAAACCAATCA

Downstream 100 bases:

>100_bases
ACATCGAAGATCTAACACAACAGCGCCCTCTTGGCGCTGTTGTTCTTTTTCTAATCCCGCTCTAATGTTACCATTTAGCC
AACTGGTGAATTTTGCTGTG

Product: aquaporin Z

Products: H2O [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNMSQKMAAEFLGTLWLVLGGCGSAVLAAAFPEVGIGLLGVAFAFGLTVLTMAFAIGHISGCHLNPAVSFGLWAGGRFPA
AELLPYIIAQVAGGIAGAGILYLIASGEEGFSLAGGFASNGFGEHSPGGYSMLSVMICEVVMTLFFLIIILGATDERAPK
GFAPIAIGLGLTLIHLISIPVSNTSVNPARSTGPALFVGDWAVSQLWLFWVAPIVGAILAGFIYRYFRAAE

Sequences:

>Translated_231_residues
MNMSQKMAAEFLGTLWLVLGGCGSAVLAAAFPEVGIGLLGVAFAFGLTVLTMAFAIGHISGCHLNPAVSFGLWAGGRFPA
AELLPYIIAQVAGGIAGAGILYLIASGEEGFSLAGGFASNGFGEHSPGGYSMLSVMICEVVMTLFFLIIILGATDERAPK
GFAPIAIGLGLTLIHLISIPVSNTSVNPARSTGPALFVGDWAVSQLWLFWVAPIVGAILAGFIYRYFRAAE
>Mature_231_residues
MNMSQKMAAEFLGTLWLVLGGCGSAVLAAAFPEVGIGLLGVAFAFGLTVLTMAFAIGHISGCHLNPAVSFGLWAGGRFPA
AELLPYIIAQVAGGIAGAGILYLIASGEEGFSLAGGFASNGFGEHSPGGYSMLSVMICEVVMTLFFLIIILGATDERAPK
GFAPIAIGLGLTLIHLISIPVSNTSVNPARSTGPALFVGDWAVSQLWLFWVAPIVGAILAGFIYRYFRAAE

Specific function: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response

COG id: COG0580

COG function: function code G; Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family [H]

Homologues:

Organism=Homo sapiens, GI4502183, Length=225, Percent_Identity=37.7777777777778, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI4502179, Length=225, Percent_Identity=35.5555555555556, Blast_Score=121, Evalue=5e-28,
Organism=Homo sapiens, GI4755125, Length=225, Percent_Identity=34.2222222222222, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI37694062, Length=233, Percent_Identity=37.3390557939914, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4502181, Length=225, Percent_Identity=34.2222222222222, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI6912506, Length=220, Percent_Identity=34.0909090909091, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI86792455, Length=225, Percent_Identity=32.4444444444444, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI45446752, Length=207, Percent_Identity=32.8502415458937, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI157266307, Length=242, Percent_Identity=31.404958677686, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI4826645, Length=241, Percent_Identity=31.5352697095436, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI22538420, Length=251, Percent_Identity=27.8884462151394, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI297307120, Length=93, Percent_Identity=39.7849462365591, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI297307116, Length=95, Percent_Identity=38.9473684210526, Blast_Score=64, Evalue=8e-11,
Organism=Homo sapiens, GI297307118, Length=95, Percent_Identity=38.9473684210526, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1787101, Length=224, Percent_Identity=71.4285714285714, Blast_Score=294, Evalue=4e-81,
Organism=Escherichia coli, GI1790362, Length=253, Percent_Identity=28.4584980237154, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71993722, Length=233, Percent_Identity=33.0472103004292, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17558372, Length=241, Percent_Identity=29.045643153527, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71992966, Length=247, Percent_Identity=27.1255060728745, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17531429, Length=241, Percent_Identity=27.8008298755187, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17531431, Length=241, Percent_Identity=27.8008298755187, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24652747, Length=218, Percent_Identity=37.6146788990826, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI45551084, Length=218, Percent_Identity=37.6146788990826, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI19922038, Length=227, Percent_Identity=31.2775330396476, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24652751, Length=227, Percent_Identity=31.2775330396476, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17136672, Length=191, Percent_Identity=30.8900523560209, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24762342, Length=198, Percent_Identity=29.7979797979798, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550503, Length=232, Percent_Identity=25.8620689655172, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012269
- InterPro:   IPR000425
- InterPro:   IPR022357 [H]

Pfam domain/function: PF00230 MIP [H]

EC number: NA

Molecular weight: Translated: 23857; Mature: 23857

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMSQKMAAEFLGTLWLVLGGCGSAVLAAAFPEVGIGLLGVAFAFGLTVLTMAFAIGHIS
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GCHLNPAVSFGLWAGGRFPAAELLPYIIAQVAGGIAGAGILYLIASGEEGFSLAGGFASN
CCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHCCCCEEEEECCCCCCEECCCCCCC
GFGEHSPGGYSMLSVMICEVVMTLFFLIIILGATDERAPKGFAPIAIGLGLTLIHLISIP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
VSNTSVNPARSTGPALFVGDWAVSQLWLFWVAPIVGAILAGFIYRYFRAAE
CCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNMSQKMAAEFLGTLWLVLGGCGSAVLAAAFPEVGIGLLGVAFAFGLTVLTMAFAIGHIS
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GCHLNPAVSFGLWAGGRFPAAELLPYIIAQVAGGIAGAGILYLIASGEEGFSLAGGFASN
CCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHCCCCEEEEECCCCCCEECCCCCCC
GFGEHSPGGYSMLSVMICEVVMTLFFLIIILGATDERAPKGFAPIAIGLGLTLIHLISIP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
VSNTSVNPARSTGPALFVGDWAVSQLWLFWVAPIVGAILAGFIYRYFRAAE
CCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O [Periplasm] [C]

Specific reaction: H2O [Periplasm] = H2O [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]