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The map label for this gene is gcp [H]

Identifier: 126173387

GI number: 126173387

Start: 1325662

End: 1326678

Strand: Direct

Name: gcp [H]

Synonym: Sbal_1148

Alternate gene names: 126173387

Gene position: 1325662-1326678 (Clockwise)

Preceding gene: 126173382

Following gene: 126173389

Centisome position: 25.85

GC content: 50.64

Gene sequence:

>1017_bases
ATGCGGGTTCTAGGTATTGAAACATCTTGTGACGAGACAGGTATCGCCGTCTATGACGATGAACTGGGCTTATTATCGCA
CACTTTATACAGTCAAGTTAAGCTGCATGCTGACTATGGTGGTGTGGTGCCTGAGTTGGCGTCGCGTGACCATGTACGCA
AAATTGTGCCGCTTATTCGTCAAGCGCTGAAAGATGCGAATACTGAAATGGCTGATCTCGACGGGATTGCCTATACCAAG
GGCCCAGGTTTGATTGGTGCTTTGCTTGTCGGCGCTTGTGTTGGGCGTTCACTGGCGTTTGCTTGGGACAAGCCTGCAAT
CGGTGTGCACCATATGGAAGGGCACCTGCTGGCGCCTATGCTTGAAGATGATGCGCCTGAGTTCCCCTTTGTGGCCTTAT
TAGTTTCTGGTGGCCATTCTATGTTGGTTAAAGTCGATGGGATTGGCCGCTATGAAGTGTTAGGTGAGTCCGTTGACGAT
GCCGCGGGTGAAGCATTCGATAAAACGGCCAAGTTGATGGGGCTGGATTATCCCGGCGGTCCGCGCTTAGCGAAACTGGC
TGCTAAAGGCTTACCCGCAGGTTATAAGTTCCCGCGGCCTATGACCGACAGACCTGGACTCGATTTTAGCTTTTCGGGTT
TAAAAACTTTTACCGCTAATACTATTGCCGCTGAACCTGACGATGAGCAAACGCGCGCCAATATTGCCCGTGCCTTTGAA
GAAGCCGTGGTTGATACGCTAGCGATTAAATGTCGCCGTGCGCTGAAGCAAACTGGCTATAACCGCTTAGTGATTGCCGG
TGGCGTGAGTGCGAATACGCGTTTAAGGGAAACCTTGGCTGAAATGATGAACTCGCTAGGTGGACAAGTATTTTATCCCC
GCGGTGAGTTTTGTACCGATAACGGCGCCATGATTGCCTTTTCGGGATTGCAGCGTTTAAAGGCGGGACAATACGAAGAT
TTAGCGGTAAAAGGTCAACCTCGATGGCCATTAGATACCTTGCCACCTGTGGCATAA

Upstream 100 bases:

>100_bases
GCTCAGTCCTATAGTGGACTCAATATGGCCTGTGCGACTGGAGTAATCGAGCGCTTGCAGGTAGAATTAGCGCCCTTTTG
TTAGCAATTGATGAGACACC

Downstream 100 bases:

>100_bases
CACGCCTTTGATGCCGATGTATTGATGCTGAAATAAAAAACTGCGCTTTTAGCGCAGTTTTTTATTGGGGTAATTTTATT
GGGCGTAATGTCATCTCAAG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRVLGIETSCDETGIAVYDDELGLLSHTLYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALKDANTEMADLDGIAYTK
GPGLIGALLVGACVGRSLAFAWDKPAIGVHHMEGHLLAPMLEDDAPEFPFVALLVSGGHSMLVKVDGIGRYEVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLAKLAAKGLPAGYKFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMNSLGGQVFYPRGEFCTDNGAMIAFSGLQRLKAGQYED
LAVKGQPRWPLDTLPPVA

Sequences:

>Translated_338_residues
MRVLGIETSCDETGIAVYDDELGLLSHTLYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALKDANTEMADLDGIAYTK
GPGLIGALLVGACVGRSLAFAWDKPAIGVHHMEGHLLAPMLEDDAPEFPFVALLVSGGHSMLVKVDGIGRYEVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLAKLAAKGLPAGYKFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMNSLGGQVFYPRGEFCTDNGAMIAFSGLQRLKAGQYED
LAVKGQPRWPLDTLPPVA
>Mature_338_residues
MRVLGIETSCDETGIAVYDDELGLLSHTLYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALKDANTEMADLDGIAYTK
GPGLIGALLVGACVGRSLAFAWDKPAIGVHHMEGHLLAPMLEDDAPEFPFVALLVSGGHSMLVKVDGIGRYEVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLAKLAAKGLPAGYKFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMNSLGGQVFYPRGEFCTDNGAMIAFSGLQRLKAGQYED
LAVKGQPRWPLDTLPPVA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=355, Percent_Identity=34.0845070422535, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI8923380, Length=333, Percent_Identity=32.7327327327327, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI1789445, Length=335, Percent_Identity=74.9253731343284, Blast_Score=515, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17557464, Length=329, Percent_Identity=30.3951367781155, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71995670, Length=330, Percent_Identity=33.9393939393939, Blast_Score=145, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6320099, Length=376, Percent_Identity=32.9787234042553, Blast_Score=173, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=28.448275862069, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI20129063, Length=342, Percent_Identity=34.5029239766082, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI21357207, Length=332, Percent_Identity=31.3253012048193, Blast_Score=153, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36288; Mature: 36288

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIETSCDETGIAVYDDELGLLSHTLYSQVKLHADYGGVVPELASRDHVRKIVPLIR
CEEEECCCCCCCCCCEEEECCHHHHHHHHHHHEEEECCCCCCCHHHHCHHHHHHHHHHHH
QALKDANTEMADLDGIAYTKGPGLIGALLVGACVGRSLAFAWDKPAIGVHHMEGHLLAPM
HHHHHCCCCHHHCCCEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCCEEECCCCEECCH
LEDDAPEFPFVALLVSGGHSMLVKVDGIGRYEVLGESVDDAAGEAFDKTAKLMGLDYPGG
HCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
PRLAKLAAKGLPAGYKFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
CHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCEEEECCEEECCCCCHHHHHHHHHHHH
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMNSLGGQVFYPRGEFCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCEECC
NGAMIAFSGLQRLKAGQYEDLAVKGQPRWPLDTLPPVA
CCCEEEEHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLGIETSCDETGIAVYDDELGLLSHTLYSQVKLHADYGGVVPELASRDHVRKIVPLIR
CEEEECCCCCCCCCCEEEECCHHHHHHHHHHHEEEECCCCCCCHHHHCHHHHHHHHHHHH
QALKDANTEMADLDGIAYTKGPGLIGALLVGACVGRSLAFAWDKPAIGVHHMEGHLLAPM
HHHHHCCCCHHHCCCEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCCEEECCCCEECCH
LEDDAPEFPFVALLVSGGHSMLVKVDGIGRYEVLGESVDDAAGEAFDKTAKLMGLDYPGG
HCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
PRLAKLAAKGLPAGYKFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
CHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCEEEECCEEECCCCCHHHHHHHHHHHH
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMNSLGGQVFYPRGEFCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCEECC
NGAMIAFSGLQRLKAGQYEDLAVKGQPRWPLDTLPPVA
CCCEEEEHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA