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The map label for this gene is galR [H]

Identifier: 126173369

GI number: 126173369

Start: 1300199

End: 1301203

Strand: Reverse

Name: galR [H]

Synonym: Sbal_1129

Alternate gene names: 126173369

Gene position: 1301203-1300199 (Counterclockwise)

Preceding gene: 126173370

Following gene: 126173366

Centisome position: 25.38

GC content: 46.37

Gene sequence:

>1005_bases
ATGGCCACTATTTACGACGTTTCGGTACTTGCAGGCGTTTCACTTGCGACTGTGTCACGGGTGATGAATAAAAACACCAA
TGTCAGTGACAAAACCAAACAAAAGGTATTAGACGCTATGGCTCAGTTGGACTATCGCCCCAATGCGATAGCCCAATCAT
TAGCGTCCAACTGCTCAAATAGTGTGGGCGTCCTAGTATCACAATTGGATGGTCCATTTTATGGGCCTATGATGACTGAA
ATTGAAGATGCCCTGCGTGATGCGGGTAAACACGTCATTATTGCCGCGGGTAAAAGCAATGAATCCCTAGAAAAGGATGC
GGTGCAGTTTTTACTGGATCGCGGCTGTGATGCGTTGATTATCGACGTGGAAGCGGTTTCAGATGACTATCTTATCGATC
TCTGTAAGCGCAGCACGCCAATCGTACTGATTAACCGCTATGTTGCCGCCATACGTGAACGCTGTATTTATCTCGATAAC
GAGCTTGGCGGTTACCTAGCGACTCAGCATATGTTGTCGTTAGGGCATGAGCATATTGCTTATATATCAGGACCTTTATT
CAAACTAGACGCTAGGCAGCGCCTGATGGGCCATAAAAAAGCGCTCACTGAATCGGCCATTCCCTATGAAAGCGAGCTGT
TCTACGAAGGGACGTTTAAAGAGTCGAGCGGTTGCGATGGCATGCGACATTTACTCAGCCTGCAACGGCCGTTTACTGCG
GTGATTTGCGCCAATGACCAAATGGCATCGGGAGCGATTTCAACCTGCCTTGAACAAGGGCTTAAGGTGCCCGAAGATTT
GTCCTTCATGGGTTATGATAACATCCCGTTTCCCCAGTATATTTCCCCTAAGCTCACCTCAGTCAGTAACCCAATCCATG
AAATGGGTAAAATGGCGGCGTTCTGGGTACTAAAACACGTTTACAATAAAACCGATGTGGAGATTGTTAGCCATTTTACG
CCTTCATTATTTGTAAGAGATTCAGCTGTTAAACGAGAAAAATAG

Upstream 100 bases:

>100_bases
AAAGTGGATGAAATCCATCTGGAATTAAATAGAGCCAGCTAATAAAAATATGCTAATCTTCAAGGCATTGTACTTTTCAG
TACCTCTAATTTGAGATGAT

Downstream 100 bases:

>100_bases
CGAATAATTGAAGGCTAGCACTGCTCTAGCCTGACCATGTTGAACTGCAAGAAGGCGCACTGCATTGCGTTTTCTCGTTA
GATTTTTCGTGCACAAGTGA

Product: periplasmic binding protein/LacI transcriptional regulator

Products: NA

Alternate protein names: Galactose operon repressor [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MATIYDVSVLAGVSLATVSRVMNKNTNVSDKTKQKVLDAMAQLDYRPNAIAQSLASNCSNSVGVLVSQLDGPFYGPMMTE
IEDALRDAGKHVIIAAGKSNESLEKDAVQFLLDRGCDALIIDVEAVSDDYLIDLCKRSTPIVLINRYVAAIRERCIYLDN
ELGGYLATQHMLSLGHEHIAYISGPLFKLDARQRLMGHKKALTESAIPYESELFYEGTFKESSGCDGMRHLLSLQRPFTA
VICANDQMASGAISTCLEQGLKVPEDLSFMGYDNIPFPQYISPKLTSVSNPIHEMGKMAAFWVLKHVYNKTDVEIVSHFT
PSLFVRDSAVKREK

Sequences:

>Translated_334_residues
MATIYDVSVLAGVSLATVSRVMNKNTNVSDKTKQKVLDAMAQLDYRPNAIAQSLASNCSNSVGVLVSQLDGPFYGPMMTE
IEDALRDAGKHVIIAAGKSNESLEKDAVQFLLDRGCDALIIDVEAVSDDYLIDLCKRSTPIVLINRYVAAIRERCIYLDN
ELGGYLATQHMLSLGHEHIAYISGPLFKLDARQRLMGHKKALTESAIPYESELFYEGTFKESSGCDGMRHLLSLQRPFTA
VICANDQMASGAISTCLEQGLKVPEDLSFMGYDNIPFPQYISPKLTSVSNPIHEMGKMAAFWVLKHVYNKTDVEIVSHFT
PSLFVRDSAVKREK
>Mature_333_residues
ATIYDVSVLAGVSLATVSRVMNKNTNVSDKTKQKVLDAMAQLDYRPNAIAQSLASNCSNSVGVLVSQLDGPFYGPMMTEI
EDALRDAGKHVIIAAGKSNESLEKDAVQFLLDRGCDALIIDVEAVSDDYLIDLCKRSTPIVLINRYVAAIRERCIYLDNE
LGGYLATQHMLSLGHEHIAYISGPLFKLDARQRLMGHKKALTESAIPYESELFYEGTFKESSGCDGMRHLLSLQRPFTAV
ICANDQMASGAISTCLEQGLKVPEDLSFMGYDNIPFPQYISPKLTSVSNPIHEMGKMAAFWVLKHVYNKTDVEIVSHFTP
SLFVRDSAVKREK

Specific function: Repressor of the galactose operon. Binds galactose as an inducer [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789202, Length=328, Percent_Identity=38.719512195122, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1788474, Length=334, Percent_Identity=36.5269461077844, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1789068, Length=298, Percent_Identity=32.5503355704698, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=31.2121212121212, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1790194, Length=331, Percent_Identity=31.4199395770393, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1790369, Length=309, Percent_Identity=30.42071197411, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1786540, Length=317, Percent_Identity=33.7539432176656, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1787906, Length=310, Percent_Identity=28.0645161290323, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787580, Length=329, Percent_Identity=25.2279635258359, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI48994940, Length=311, Percent_Identity=25.7234726688103, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790715, Length=311, Percent_Identity=24.7588424437299, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789456, Length=335, Percent_Identity=24.1791044776119, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1786268, Length=275, Percent_Identity=23.2727272727273, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790689, Length=312, Percent_Identity=22.7564102564103, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36897; Mature: 36766

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIYDVSVLAGVSLATVSRVMNKNTNVSDKTKQKVLDAMAQLDYRPNAIAQSLASNCSN
CCEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
SVGVLVSQLDGPFYGPMMTEIEDALRDAGKHVIIAAGKSNESLEKDAVQFLLDRGCDALI
CHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEE
IDVEAVSDDYLIDLCKRSTPIVLINRYVAAIRERCIYLDNELGGYLATQHMLSLGHEHIA
EEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCHHHHH
YISGPLFKLDARQRLMGHKKALTESAIPYESELFYEGTFKESSGCDGMRHLLSLQRPFTA
HHCCCCEEECHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCEE
VICANDQMASGAISTCLEQGLKVPEDLSFMGYDNIPFPQYISPKLTSVSNPIHEMGKMAA
EEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHH
FWVLKHVYNKTDVEIVSHFTPSLFVRDSAVKREK
HHHHHHHHCCCHHHHHHHCCCCCEEECCHHCCCC
>Mature Secondary Structure 
ATIYDVSVLAGVSLATVSRVMNKNTNVSDKTKQKVLDAMAQLDYRPNAIAQSLASNCSN
CEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
SVGVLVSQLDGPFYGPMMTEIEDALRDAGKHVIIAAGKSNESLEKDAVQFLLDRGCDALI
CHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEE
IDVEAVSDDYLIDLCKRSTPIVLINRYVAAIRERCIYLDNELGGYLATQHMLSLGHEHIA
EEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCHHHHH
YISGPLFKLDARQRLMGHKKALTESAIPYESELFYEGTFKESSGCDGMRHLLSLQRPFTA
HHCCCCEEECHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCEE
VICANDQMASGAISTCLEQGLKVPEDLSFMGYDNIPFPQYISPKLTSVSNPIHEMGKMAA
EEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHH
FWVLKHVYNKTDVEIVSHFTPSLFVRDSAVKREK
HHHHHHHHCCCHHHHHHHCCCCCEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6283521; 9278503; 6350601; 8188660; 8982002 [H]