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The map label for this gene is nagA [H]

Identifier: 126173328

GI number: 126173328

Start: 1251103

End: 1252239

Strand: Direct

Name: nagA [H]

Synonym: Sbal_1086

Alternate gene names: 126173328

Gene position: 1251103-1252239 (Clockwise)

Preceding gene: 126173327

Following gene: 126173329

Centisome position: 24.4

GC content: 51.54

Gene sequence:

>1137_bases
ATGAAAATTACCTTGATCGCCGAGCGTATTTTTGATGGTGAATATTTCCATCAAGATGTGCCTGTAACTGTTGAAGACGG
GCACATTCTGGCGTTTGATACGGTTGTTGGCGCGAAGGAAATCCGCCAAGTCGGAACGCTGGTGCCAGGTTTTATCGATG
TACAAGTGAACGGTGGCGGCGGGGCGTTATTCAATGCCGATCCGAGTGTTAATTGCATTGAAACTATCGGCCGTGCCCAT
GCGCGTTTTGGCACGACAGGTTTTTTACCTACGCTTATTACCGACGATGTCAGCGTGATGGCAAATGCAGCCGATGCAGT
GGCCGAGGCTTTAGTTAAGGGTAGCGCTGGCGTTTTAGGGGTGCATTTTGAAGGACCACATTTATCTGTGCCTAAAAAAG
GCGTGCATCCGCAGGGGTTTATTCGCGAAATCACCGATGCCGAACTCGCGGTATTTTGTCGTCAAGATCTGGGGATTAAA
GTTGTCACGCTTGCGCCTGAGAATGTGTCGCCAGAGGTGATCCGTACGCTCGTTGCTTCGGGCGTTAAGGTGTGTTTGGG
CCATTCTAATGCCGACTACGATACTGTGATTACAGCATTAGCGGCAGGCGCGACGGGCTTTACCCATCTTTATAATGCGA
TGTCACCACTCGGTTCCCGTGAGCCGGGCATGGTTGGTGCGGCGATTGAGAGTGAAACCGCTTGGTGTGGTTTGATTGTC
GATGGTCACCATGTGCACCCTGCGGCGGCAAAGGTTGCACTACGGGCAAAACCGAGGGGCAAGATGATGTTAGTCACCGA
TGCTATGCCGCCAGTTGGTATGGAGGATGAGACTAGCTTCGAGCTCTTTGGTACTCGAGTGTTAAGAGTCGGCGACAGAT
TAAATGCCGTGACAGGTGAGCTGGCGGGCTGTGTGCTCGATATGGCAACTGCGGTCAATAATACTGTGAACTTGTTGGGT
TTACCTTTGGCGGAAGCCTTGAGAATGGCGGCGTTATATCCCGCACAGTTCCTCGGGATTGACCATAAGGCTGGCCGTTT
AGCACTGGGACACAGGGCTGACTTTGTCTTGCTCGATGTGCAGAACAAAGTGCAGGCAAACTACATTGCGGGACAAGCAG
TTTATACACACCCTTAA

Upstream 100 bases:

>100_bases
CGATTAAGCAGCTGCATGATTAAACCTGTTCAGCTAAGCCCGCGCAGTAACTTAATTTAAGACCTAAGTCACTCGTGTTA
TTTATTGAAAGAGGTTTGCG

Downstream 100 bases:

>100_bases
ATTGCTTTTGTAGTTTAGGCGCTCTGAAATTCGTATCTTCAGGTAGCTTGGGTATAGCCCTTGTCGTATTTTGATGACAG
GGGCTAAGTTTTTTTTTTGT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKITLIAERIFDGEYFHQDVPVTVEDGHILAFDTVVGAKEIRQVGTLVPGFIDVQVNGGGGALFNADPSVNCIETIGRAH
ARFGTTGFLPTLITDDVSVMANAADAVAEALVKGSAGVLGVHFEGPHLSVPKKGVHPQGFIREITDAELAVFCRQDLGIK
VVTLAPENVSPEVIRTLVASGVKVCLGHSNADYDTVITALAAGATGFTHLYNAMSPLGSREPGMVGAAIESETAWCGLIV
DGHHVHPAAAKVALRAKPRGKMMLVTDAMPPVGMEDETSFELFGTRVLRVGDRLNAVTGELAGCVLDMATAVNNTVNLLG
LPLAEALRMAALYPAQFLGIDHKAGRLALGHRADFVLLDVQNKVQANYIAGQAVYTHP

Sequences:

>Translated_378_residues
MKITLIAERIFDGEYFHQDVPVTVEDGHILAFDTVVGAKEIRQVGTLVPGFIDVQVNGGGGALFNADPSVNCIETIGRAH
ARFGTTGFLPTLITDDVSVMANAADAVAEALVKGSAGVLGVHFEGPHLSVPKKGVHPQGFIREITDAELAVFCRQDLGIK
VVTLAPENVSPEVIRTLVASGVKVCLGHSNADYDTVITALAAGATGFTHLYNAMSPLGSREPGMVGAAIESETAWCGLIV
DGHHVHPAAAKVALRAKPRGKMMLVTDAMPPVGMEDETSFELFGTRVLRVGDRLNAVTGELAGCVLDMATAVNNTVNLLG
LPLAEALRMAALYPAQFLGIDHKAGRLALGHRADFVLLDVQNKVQANYIAGQAVYTHP
>Mature_378_residues
MKITLIAERIFDGEYFHQDVPVTVEDGHILAFDTVVGAKEIRQVGTLVPGFIDVQVNGGGGALFNADPSVNCIETIGRAH
ARFGTTGFLPTLITDDVSVMANAADAVAEALVKGSAGVLGVHFEGPHLSVPKKGVHPQGFIREITDAELAVFCRQDLGIK
VVTLAPENVSPEVIRTLVASGVKVCLGHSNADYDTVITALAAGATGFTHLYNAMSPLGSREPGMVGAAIESETAWCGLIV
DGHHVHPAAAKVALRAKPRGKMMLVTDAMPPVGMEDETSFELFGTRVLRVGDRLNAVTGELAGCVLDMATAVNNTVNLLG
LPLAEALRMAALYPAQFLGIDHKAGRLALGHRADFVLLDVQNKVQANYIAGQAVYTHP

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=418, Percent_Identity=35.6459330143541, Blast_Score=188, Evalue=7e-48,
Organism=Homo sapiens, GI224922791, Length=410, Percent_Identity=36.0975609756098, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1786892, Length=377, Percent_Identity=38.4615384615385, Blast_Score=212, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17553768, Length=353, Percent_Identity=32.0113314447592, Blast_Score=151, Evalue=5e-37,
Organism=Drosophila melanogaster, GI19920392, Length=343, Percent_Identity=38.7755102040816, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI281361140, Length=355, Percent_Identity=37.4647887323944, Blast_Score=188, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39825; Mature: 39825

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITLIAERIFDGEYFHQDVPVTVEDGHILAFDTVVGAKEIRQVGTLVPGFIDVQVNGGG
CEEEEEEHHHCCCHHHCCCCCEEEECCEEEEEEHHHCHHHHHHHHCCCCCEEEEEEECCC
GALFNADPSVNCIETIGRAHARFGTTGFLPTLITDDVSVMANAADAVAEALVKGSAGVLG
EEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEE
VHFEGPHLSVPKKGVHPQGFIREITDAELAVFCRQDLGIKVVTLAPENVSPEVIRTLVAS
EEECCCCCCCCCCCCCCCHHHHHHCCHHHEEEECCCCCEEEEEECCCCCCHHHHHHHHHC
GVKVCLGHSNADYDTVITALAAGATGFTHLYNAMSPLGSREPGMVGAAIESETAWCGLIV
CCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEE
DGHHVHPAAAKVALRAKPRGKMMLVTDAMPPVGMEDETSFELFGTRVLRVGDRLNAVTGE
ECCEECHHHHEEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
LAGCVLDMATAVNNTVNLLGLPLAEALRMAALYPAQFLGIDHKAGRLALGHRADFVLLDV
HHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCHHHHCCCCCCCEEEECCCCCEEEEEC
QNKVQANYIAGQAVYTHP
CCCCEEEEEECCEEEECC
>Mature Secondary Structure
MKITLIAERIFDGEYFHQDVPVTVEDGHILAFDTVVGAKEIRQVGTLVPGFIDVQVNGGG
CEEEEEEHHHCCCHHHCCCCCEEEECCEEEEEEHHHCHHHHHHHHCCCCCEEEEEEECCC
GALFNADPSVNCIETIGRAHARFGTTGFLPTLITDDVSVMANAADAVAEALVKGSAGVLG
EEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEE
VHFEGPHLSVPKKGVHPQGFIREITDAELAVFCRQDLGIKVVTLAPENVSPEVIRTLVAS
EEECCCCCCCCCCCCCCCHHHHHHCCHHHEEEECCCCCEEEEEECCCCCCHHHHHHHHHC
GVKVCLGHSNADYDTVITALAAGATGFTHLYNAMSPLGSREPGMVGAAIESETAWCGLIV
CCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEE
DGHHVHPAAAKVALRAKPRGKMMLVTDAMPPVGMEDETSFELFGTRVLRVGDRLNAVTGE
ECCEECHHHHEEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
LAGCVLDMATAVNNTVNLLGLPLAEALRMAALYPAQFLGIDHKAGRLALGHRADFVLLDV
HHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCHHHHCCCCCCCEEEECCCCCEEEEEC
QNKVQANYIAGQAVYTHP
CCCCEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]