Click here to switch to the map view.

The map label for this gene is clpB [H]

Identifier: 126173263

GI number: 126173263

Start: 1164041

End: 1166614

Strand: Direct

Name: clpB [H]

Synonym: Sbal_1019

Alternate gene names: 126173263

Gene position: 1164041-1166614 (Clockwise)

Preceding gene: 126173262

Following gene: 126173265

Centisome position: 22.7

GC content: 49.38

Gene sequence:

>2574_bases
ATGCGACTCGATCGTATGACCAATAAATTTCAGCTTGCCATCTCAGATGCCCAGTCTCTCGCACTCGGGCGTGATCATCA
GTTTATTGAACCGCTGCATTTGATGATGGCATTGTTGAACCAAGATTCAGGTTCAATCCATCCCTTATTGACCCAAGCTG
GCATTCGCGTGAGTGCGCTGCGCTCGCTTTTGAGTCAAGAGCTGGAACGTTTACCTCAAGTCGAAGGTACGGGCGGCGAT
GTGCAATTATCCCAAGGTTTAATACGTTTATTAAATCTGTGCGATAAATTGGCGCAAAAGCGTAAAGACAAATATATCTC
TAGCGAGTTATTTGTATTAGCTGCGTTAGAAGGAGGCGATGCCCTCGCGCAAGCGTTGAAAAAAGCCGGCGCGACTAAAG
AGTTGATGGAGCAAACCATTGAACAAATGCGCGGCGGCCAAAAAGTGGATGATCCGAACGCTGAAGATCAACGCCAAGCG
TTGAAGAAGTTTACTATCGATCTGACCGAGCGAGCCGAACAAGGCAAGTTAGATCCTGTGATCGGCCGTGACGATGAAAT
TCGCCGCACGATCCAAGTATTACAACGTCGCAGTAAAAACAACCCCGTCCTTATCGGTGAACCGGGTGTGGGTAAAACGG
CGATTGTTGAAGGACTTGCCCAGCGTATCGTTAATGGTGAAGTCCCCGAGGGCATAAAAAATAAGCGCGTCTTATCCCTC
GATATGGGCTCATTGATTGCGGGCGCTAAATATCGCGGTGAGTTCGAAGAACGTTTAAAAGCGGTATTGAATGAGTTAGC
GCAGGAAGAAGGTCAAGTAATCCTCTTCATCGACGAGCTGCATACTATGGTCGGCGCCGGTAAAGGTGAAGGCGCAATGG
ATGCGGGTAACATGCTCAAACCTGCGTTAGCGCGTGGTGATTTGCACTGTGTGGGCGCTACCACGCTTGATGAGTATCGT
CAGTACATTGAAAAAGATGCGGCGCTTGAACGTCGTTTCCAAAAAGTGCTGGTGGATGAGCCAAGCGTTGAAGACACCAT
TGCCATTTTGCGTGGCCTGAAAGAACGTTACGAGCTGCATCACCATGTGGAAATTACCGATCCGGCGATTGTGGCGGCGG
CGACTATGTCGCATCGTTATGTGTCGGACCGTAAGTTGCCCGATAAAGCGATCGATTTGATCGACGAAGCGGCATCGAGC
ATCCGTATGCAGATGGACTCTAAACCTGAGTCACTCGACCGGCTCGAACGTCGTGCTATCCAGCTCAAACTGGAGGAGCA
AGCGTTAGCCAAAGAAAATGATGAGGCGAGCCGTCGCAGGCTTGACCATCTGCAAGAGGAATTACGCGACGTTGAAGCTA
AAGCTTCAGAGTTGAACGAAATCTGGCGTACTGAAAAAGCCGCACTAGCGGGAACTCAGCACATTAAAGCCGATCTCGAA
CAGGCTCGAATGGACTTAGAAGTGGCGCGTCGTGCGGGTGATTTAACTCGGATGTCTGAGCTGCAATACGGTCGTATTCC
TGAGCTTGAAAAACAGCTCGATTTGGCATCGCAAGCCGAAATGCAGGACATGACGTTATTGCGTAACAAGGTCACTGAGT
TCGAAATCGCCGAAGTCTTGTCGAAAGCGACGGGAATTCCCGTATCGAAAATGCTTGAAGGCGAGCGCGAAAAATTACTG
CAAATGGAAGTGGCGCTGCACGAGCGGGTGATAGGCCAAAACGAAGCCGTTGATGCGGTCGCGAATGCGATTCGTCGTAG
CCGCGCGGGTCTAGCGGATCCAAATCGCCCGATTGGCTCGTTCTTGTTCTTAGGCCCAACCGGTGTGGGTAAAACTGAGC
TGTGTAAATCACTGGCGAGGTTCTTATTCGATACCGAATCGGCCTTAGTGCGCATTGATATGTCTGAGTTTATGGAGAAA
CACTCAGTATCGCGTTTAGTGGGTGCGCCTCCTGGATACGTAGGTTATGAAGAGGGCGGTTACTTAACGGAAGCCGTTCG
TCGTAAACCGTATTCGGTGATATTGCTCGACGAAGTCGAGAAAGCGCATCCCGATGTGTTTAACATCTTACTGCAAGTGC
TTGATGATGGACGCTTAACCGATGGTCAAGGTCGTACTGTAGATTTTAGAAATACAGTGATCATCATGACCTCGAACTTA
GGCTCCGACATTATCCAAGAAGGATTTGGTCAAGTGACCTATGCAGAGATGAAAGCGGCGGTAATGAATGTGGTTACTCA
CAGTTTCAGACCTGAGTTTTTAAACCGTATCGATGAATCTGTGGTGTTCCATCCATTGGATGCTGCCAATATCAAGCGTA
TTGCTTCGATACAGATTGCTTCCTTACGCCAACGTTTGGCGGAAAAGGACTATACATTGGAGATCACCGACGACGCATTA
TCACTGATTGCGGAAATTGGTTTCGATCCTGTGTATGGCGCAAGACCGTTGAAACGGGCATTGCAGCAAGAAGTCGAAAA
CCCGCTGGCGCAGAAATTACTGCGTGGCGACTTGTTACCGGGTAAACCGATCAAGGTCAGCTGTGCGGGTGGCGAATTAG
TGTTCGAGCAATAA

Upstream 100 bases:

>100_bases
ATTAAGATCTCTTCATTAGCGGTACTGATTTAACGCCACTAAATTGGCAAGATATCTTGTGGATTGGCATATCTCTACTT
TGTGAGTTTTAGGAGGCTGT

Downstream 100 bases:

>100_bases
CCAGTAGCTGTAACTTAGTGTGTTGTTTGAATGCGATACGTTAACAGCAAGCTTGAAGTTGGATAGGTTGAAATAGGCGA
ACTGAAATAAGCGTTCTTGA

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 857; Mature: 857

Protein sequence:

>857_residues
MRLDRMTNKFQLAISDAQSLALGRDHQFIEPLHLMMALLNQDSGSIHPLLTQAGIRVSALRSLLSQELERLPQVEGTGGD
VQLSQGLIRLLNLCDKLAQKRKDKYISSELFVLAALEGGDALAQALKKAGATKELMEQTIEQMRGGQKVDDPNAEDQRQA
LKKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGIKNKRVLSL
DMGSLIAGAKYRGEFEERLKAVLNELAQEEGQVILFIDELHTMVGAGKGEGAMDAGNMLKPALARGDLHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYELHHHVEITDPAIVAAATMSHRYVSDRKLPDKAIDLIDEAASS
IRMQMDSKPESLDRLERRAIQLKLEEQALAKENDEASRRRLDHLQEELRDVEAKASELNEIWRTEKAALAGTQHIKADLE
QARMDLEVARRAGDLTRMSELQYGRIPELEKQLDLASQAEMQDMTLLRNKVTEFEIAEVLSKATGIPVSKMLEGEREKLL
QMEVALHERVIGQNEAVDAVANAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKSLARFLFDTESALVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
GSDIIQEGFGQVTYAEMKAAVMNVVTHSFRPEFLNRIDESVVFHPLDAANIKRIASIQIASLRQRLAEKDYTLEITDDAL
SLIAEIGFDPVYGARPLKRALQQEVENPLAQKLLRGDLLPGKPIKVSCAGGELVFEQ

Sequences:

>Translated_857_residues
MRLDRMTNKFQLAISDAQSLALGRDHQFIEPLHLMMALLNQDSGSIHPLLTQAGIRVSALRSLLSQELERLPQVEGTGGD
VQLSQGLIRLLNLCDKLAQKRKDKYISSELFVLAALEGGDALAQALKKAGATKELMEQTIEQMRGGQKVDDPNAEDQRQA
LKKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGIKNKRVLSL
DMGSLIAGAKYRGEFEERLKAVLNELAQEEGQVILFIDELHTMVGAGKGEGAMDAGNMLKPALARGDLHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYELHHHVEITDPAIVAAATMSHRYVSDRKLPDKAIDLIDEAASS
IRMQMDSKPESLDRLERRAIQLKLEEQALAKENDEASRRRLDHLQEELRDVEAKASELNEIWRTEKAALAGTQHIKADLE
QARMDLEVARRAGDLTRMSELQYGRIPELEKQLDLASQAEMQDMTLLRNKVTEFEIAEVLSKATGIPVSKMLEGEREKLL
QMEVALHERVIGQNEAVDAVANAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKSLARFLFDTESALVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
GSDIIQEGFGQVTYAEMKAAVMNVVTHSFRPEFLNRIDESVVFHPLDAANIKRIASIQIASLRQRLAEKDYTLEITDDAL
SLIAEIGFDPVYGARPLKRALQQEVENPLAQKLLRGDLLPGKPIKVSCAGGELVFEQ
>Mature_857_residues
MRLDRMTNKFQLAISDAQSLALGRDHQFIEPLHLMMALLNQDSGSIHPLLTQAGIRVSALRSLLSQELERLPQVEGTGGD
VQLSQGLIRLLNLCDKLAQKRKDKYISSELFVLAALEGGDALAQALKKAGATKELMEQTIEQMRGGQKVDDPNAEDQRQA
LKKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGIKNKRVLSL
DMGSLIAGAKYRGEFEERLKAVLNELAQEEGQVILFIDELHTMVGAGKGEGAMDAGNMLKPALARGDLHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYELHHHVEITDPAIVAAATMSHRYVSDRKLPDKAIDLIDEAASS
IRMQMDSKPESLDRLERRAIQLKLEEQALAKENDEASRRRLDHLQEELRDVEAKASELNEIWRTEKAALAGTQHIKADLE
QARMDLEVARRAGDLTRMSELQYGRIPELEKQLDLASQAEMQDMTLLRNKVTEFEIAEVLSKATGIPVSKMLEGEREKLL
QMEVALHERVIGQNEAVDAVANAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKSLARFLFDTESALVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
GSDIIQEGFGQVTYAEMKAAVMNVVTHSFRPEFLNRIDESVVFHPLDAANIKRIASIQIASLRQRLAEKDYTLEITDDAL
SLIAEIGFDPVYGARPLKRALQQEVENPLAQKLLRGDLLPGKPIKVSCAGGELVFEQ

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=309, Percent_Identity=37.5404530744337, Blast_Score=211, Evalue=3e-54,
Organism=Escherichia coli, GI1788943, Length=848, Percent_Identity=78.1839622641509, Blast_Score=1365, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=421, Percent_Identity=39.1923990498812, Blast_Score=276, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6320464, Length=728, Percent_Identity=52.8846153846154, Blast_Score=768, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=859, Percent_Identity=41.6763678696158, Blast_Score=655, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95357; Mature: 95357

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDRMTNKFQLAISDAQSLALGRDHQFIEPLHLMMALLNQDSGSIHPLLTQAGIRVSAL
CCCCHHCCHHEEEEHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHH
RSLLSQELERLPQVEGTGGDVQLSQGLIRLLNLCDKLAQKRKDKYISSELFVLAALEGGD
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCH
ALAQALKKAGATKELMEQTIEQMRGGQKVDDPNAEDQRQALKKFTIDLTERAEQGKLDPV
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
IGRDDEIRRTIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGIKNKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
DMGSLIAGAKYRGEFEERLKAVLNELAQEEGQVILFIDELHTMVGAGKGEGAMDAGNMLK
CHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALARGDLHCVGATTLDEYRQYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYELH
HHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HHVEITDPAIVAAATMSHRYVSDRKLPDKAIDLIDEAASSIRMQMDSKPESLDRLERRAI
HCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QLKLEEQALAKENDEASRRRLDHLQEELRDVEAKASELNEIWRTEKAALAGTQHIKADLE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARMDLEVARRAGDLTRMSELQYGRIPELEKQLDLASQAEMQDMTLLRNKVTEFEIAEVL
HHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKATGIPVSKMLEGEREKLLQMEVALHERVIGQNEAVDAVANAIRRSRAGLADPNRPIGS
HHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
FLFLGPTGVGKTELCKSLARFLFDTESALVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGG
EEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
YLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
HHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCC
GSDIIQEGFGQVTYAEMKAAVMNVVTHSFRPEFLNRIDESVVFHPLDAANIKRIASIQIA
CHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHH
SLRQRLAEKDYTLEITDDALSLIAEIGFDPVYGARPLKRALQQEVENPLAQKLLRGDLLP
HHHHHHHCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCC
GKPIKVSCAGGELVFEQ
CCCEEEEECCCCEEECC
>Mature Secondary Structure
MRLDRMTNKFQLAISDAQSLALGRDHQFIEPLHLMMALLNQDSGSIHPLLTQAGIRVSAL
CCCCHHCCHHEEEEHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHH
RSLLSQELERLPQVEGTGGDVQLSQGLIRLLNLCDKLAQKRKDKYISSELFVLAALEGGD
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCH
ALAQALKKAGATKELMEQTIEQMRGGQKVDDPNAEDQRQALKKFTIDLTERAEQGKLDPV
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
IGRDDEIRRTIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGIKNKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
DMGSLIAGAKYRGEFEERLKAVLNELAQEEGQVILFIDELHTMVGAGKGEGAMDAGNMLK
CHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALARGDLHCVGATTLDEYRQYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYELH
HHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HHVEITDPAIVAAATMSHRYVSDRKLPDKAIDLIDEAASSIRMQMDSKPESLDRLERRAI
HCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QLKLEEQALAKENDEASRRRLDHLQEELRDVEAKASELNEIWRTEKAALAGTQHIKADLE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARMDLEVARRAGDLTRMSELQYGRIPELEKQLDLASQAEMQDMTLLRNKVTEFEIAEVL
HHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKATGIPVSKMLEGEREKLLQMEVALHERVIGQNEAVDAVANAIRRSRAGLADPNRPIGS
HHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
FLFLGPTGVGKTELCKSLARFLFDTESALVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGG
EEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
YLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
HHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCC
GSDIIQEGFGQVTYAEMKAAVMNVVTHSFRPEFLNRIDESVVFHPLDAANIKRIASIQIA
CHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHH
SLRQRLAEKDYTLEITDDALSLIAEIGFDPVYGARPLKRALQQEVENPLAQKLLRGDLLP
HHHHHHHCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCC
GKPIKVSCAGGELVFEQ
CCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]