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The map label for this gene is ruvA [H]

Identifier: 125625244

GI number: 125625244

Start: 2443004

End: 2443597

Strand: Reverse

Name: ruvA [H]

Synonym: llmg_2488

Alternate gene names: 125625244

Gene position: 2443597-2443004 (Counterclockwise)

Preceding gene: 125625245

Following gene: 125625243

Centisome position: 96.6

GC content: 37.37

Gene sequence:

>594_bases
ATGTTTGAATATCTAAATGGAAAATTAGTTAAAATTTCCCCAACAAATATCGTGATTGACCTATCGGGAATAGGTTATCT
TATCAGCGTAGCCAATCCTTATGCTTGGTCTGCTTTAATGAATACAGAAGTAAAGATTTATGTTCATCAAGTTATTCGGG
AAGATGCACATAGCTTATATGGTTTTGTTAATGAGTCTGAAAAAGCTTTATTCTTGCGCCTGATTAGTGTTTCAGGAATC
GGCCCAAAGTCAGCTCTAGCTATTATTGCGGCAGCTGACAATGAAGGTTTAATCAATGCTATCGATAATAGCGATATTAA
GTATTTGACGAAATTTCCAGGAGTTGGTAAAAAAACAGCCATGCAAATGGTGCTTGATTTAGCTGGGAAATTTGATGCGA
CAGGAGCTGTTGGGATTTCCCTTCTTGATGCTGCGCCTGCTAGTAATCTGGCTTTAGAAGAAGCCATTGAAGCTTTGCAA
GCTTTGGGCTATAAGGCGACAGAACTCAAGAAAATTGAGAAAAAATTGGCGCAAGAAGCAGGATTAACCAGTGAAGAATA
TATCAAATCAGCCTTAAAACTTATGATGAAATAA

Upstream 100 bases:

>100_bases
TCAAGAAACGCATCGTTCAAAAGCGGCCTCTTGGAAAGATTTTGAGTAAAAGAAAAGAACTGGCAGCGGTCAGTTAATCA
AAAAATTAGAAAAGTAAAAA

Downstream 100 bases:

>100_bases
AAATTACTGACAAAAAATCTAGTTGTCCTGTGATCAGGCTGTCAGTAAAATACAAACAGCTAGAGAAGTAATTGTTATTC
GTAAGTGAATCTTTAAAGTT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MFEYLNGKLVKISPTNIVIDLSGIGYLISVANPYAWSALMNTEVKIYVHQVIREDAHSLYGFVNESEKALFLRLISVSGI
GPKSALAIIAAADNEGLINAIDNSDIKYLTKFPGVGKKTAMQMVLDLAGKFDATGAVGISLLDAAPASNLALEEAIEALQ
ALGYKATELKKIEKKLAQEAGLTSEEYIKSALKLMMK

Sequences:

>Translated_197_residues
MFEYLNGKLVKISPTNIVIDLSGIGYLISVANPYAWSALMNTEVKIYVHQVIREDAHSLYGFVNESEKALFLRLISVSGI
GPKSALAIIAAADNEGLINAIDNSDIKYLTKFPGVGKKTAMQMVLDLAGKFDATGAVGISLLDAAPASNLALEEAIEALQ
ALGYKATELKKIEKKLAQEAGLTSEEYIKSALKLMMK
>Mature_197_residues
MFEYLNGKLVKISPTNIVIDLSGIGYLISVANPYAWSALMNTEVKIYVHQVIREDAHSLYGFVNESEKALFLRLISVSGI
GPKSALAIIAAADNEGLINAIDNSDIKYLTKFPGVGKKTAMQMVLDLAGKFDATGAVGISLLDAAPASNLALEEAIEALQ
ALGYKATELKKIEKKLAQEAGLTSEEYIKSALKLMMK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=34.3283582089552, Blast_Score=121, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 21210; Mature: 21210

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEYLNGKLVKISPTNIVIDLSGIGYLISVANPYAWSALMNTEVKIYVHQVIREDAHSLY
CCCCCCCEEEEEECCEEEEEECCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
GFVNESEKALFLRLISVSGIGPKSALAIIAAADNEGLINAIDNSDIKYLTKFPGVGKKTA
HHHCCCCCEEHHHHHHHCCCCCCCEEEEEEECCCCCCEEECCCCCCEEEECCCCCCHHHH
MQMVLDLAGKFDATGAVGISLLDAAPASNLALEEAIEALQALGYKATELKKIEKKLAQEA
HHHHHHHHCCCCCCCHHHEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GLTSEEYIKSALKLMMK
CCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFEYLNGKLVKISPTNIVIDLSGIGYLISVANPYAWSALMNTEVKIYVHQVIREDAHSLY
CCCCCCCEEEEEECCEEEEEECCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
GFVNESEKALFLRLISVSGIGPKSALAIIAAADNEGLINAIDNSDIKYLTKFPGVGKKTA
HHHCCCCCEEHHHHHHHCCCCCCCEEEEEEECCCCCCEEECCCCCCEEEECCCCCCHHHH
MQMVLDLAGKFDATGAVGISLLDAAPASNLALEEAIEALQALGYKATELKKIEKKLAQEA
HHHHHHHHCCCCCCCHHHEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GLTSEEYIKSALKLMMK
CCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]