Click here to switch to the map view.

The map label for this gene is ruvB [H]

Identifier: 125625243

GI number: 125625243

Start: 2441855

End: 2442856

Strand: Reverse

Name: ruvB [H]

Synonym: llmg_2487

Alternate gene names: 125625243

Gene position: 2442856-2441855 (Counterclockwise)

Preceding gene: 125625244

Following gene: 125625242

Centisome position: 96.58

GC content: 39.92

Gene sequence:

>1002_bases
ATGAATGATATATTAAATAAAGAGCCAATGGAAGAGGATTATGGCATTGAAAAATCTCTTCGCCCGCAATTTTTCAATCA
ATACATTGGTCAAGACAAAGTCAAAGAACAGTTAGAAATCTTTATTAAAGCGGCAAAAATGCGGGAAGAAGTTTTGGACC
ATGTTTTACTCTTTGGTCCTCCCGGGCTTGGTAAAACAACCATGGCTTTTGTGATTGCCAATGAACTTGGGGTTAATATT
AAACAAACCGCTGGTCCTGCTATTGAGAAACCAGGTGATTTAGTCGCAATTTTGAATGAATTAGAACCTGGGGATGTCCT
ATTTATTGATGAAATTCATCGGATGCCCATGCAGGTTGAAGAAGTGCTTTATAGCGCCATGGAAGATTTCTACATTGATA
TCATGCTTGGCTCTGGTGACGGCTCACGTTCGGTTCATTTAGACTTACCACCTTTTACTTTGGTTGGCGCAACAACGAGA
GCTGGGATGCTTTCTAATCCATTGCGGGCCCGCTTTGGTATTTCTAGTCACATGGAATATTATCAAGAGCGTGATTTAGA
GGAAATTGTTAAAAGAACAGCTGATATTTTTGAGGTTGAAGTCATTGATAATGCTGCTATGGAAATTGCTTTACGCAGTC
GTGGGACTCCGCGGATTGCCAATCGTTTACTTAAAAGAGTGCGTGATTTTGCCCAAATAATGGGTGACGGACGAGTGGAT
AAAGCTATTACAGACAAAGCCTTGACAATTCTTGATGTTGATGCTGCTGGTTTGGATTATATTGACCAAAAAATATTGCG
CACAATGATTGAAATATATCACGGTGGACCTGTTGGAATTGGGACTTTGGCAGTAAATATTGCTGAGGACCGCGAAACTG
TCGAAGACATGTATGAGCCCTATTTGATTCAAAAAGGATTTTTGATGAGAACTAAACAGGGACGTAAAGTTACCCAAAGA
GCTTATGAGCATTTGGGTTACGTTTATAATGAAGAGGAATGA

Upstream 100 bases:

>100_bases
AAATACAAACAGCTAGAGAAGTAATTGTTATTCGTAAGTGAATCTTTAAAGTTGATAAATGCACTGACAGCACATGAATT
TCTAAAAGGAAGTCGAAACG

Downstream 100 bases:

>100_bases
TAGAAATTCTAAAAGGAAAAGTTTGTCAGATTTTGGCAAGCTTTTTCCTTTTAGAATTCTGTCAGTAATATCTTATGAAA
TAAGGTATAATAGAATAAAT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNDILNKEPMEEDYGIEKSLRPQFFNQYIGQDKVKEQLEIFIKAAKMREEVLDHVLLFGPPGLGKTTMAFVIANELGVNI
KQTAGPAIEKPGDLVAILNELEPGDVLFIDEIHRMPMQVEEVLYSAMEDFYIDIMLGSGDGSRSVHLDLPPFTLVGATTR
AGMLSNPLRARFGISSHMEYYQERDLEEIVKRTADIFEVEVIDNAAMEIALRSRGTPRIANRLLKRVRDFAQIMGDGRVD
KAITDKALTILDVDAAGLDYIDQKILRTMIEIYHGGPVGIGTLAVNIAEDRETVEDMYEPYLIQKGFLMRTKQGRKVTQR
AYEHLGYVYNEEE

Sequences:

>Translated_333_residues
MNDILNKEPMEEDYGIEKSLRPQFFNQYIGQDKVKEQLEIFIKAAKMREEVLDHVLLFGPPGLGKTTMAFVIANELGVNI
KQTAGPAIEKPGDLVAILNELEPGDVLFIDEIHRMPMQVEEVLYSAMEDFYIDIMLGSGDGSRSVHLDLPPFTLVGATTR
AGMLSNPLRARFGISSHMEYYQERDLEEIVKRTADIFEVEVIDNAAMEIALRSRGTPRIANRLLKRVRDFAQIMGDGRVD
KAITDKALTILDVDAAGLDYIDQKILRTMIEIYHGGPVGIGTLAVNIAEDRETVEDMYEPYLIQKGFLMRTKQGRKVTQR
AYEHLGYVYNEEE
>Mature_333_residues
MNDILNKEPMEEDYGIEKSLRPQFFNQYIGQDKVKEQLEIFIKAAKMREEVLDHVLLFGPPGLGKTTMAFVIANELGVNI
KQTAGPAIEKPGDLVAILNELEPGDVLFIDEIHRMPMQVEEVLYSAMEDFYIDIMLGSGDGSRSVHLDLPPFTLVGATTR
AGMLSNPLRARFGISSHMEYYQERDLEEIVKRTADIFEVEVIDNAAMEIALRSRGTPRIANRLLKRVRDFAQIMGDGRVD
KAITDKALTILDVDAAGLDYIDQKILRTMIEIYHGGPVGIGTLAVNIAEDRETVEDMYEPYLIQKGFLMRTKQGRKVTQR
AYEHLGYVYNEEE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=315, Percent_Identity=57.1428571428571, Blast_Score=388, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37662; Mature: 37662

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDILNKEPMEEDYGIEKSLRPQFFNQYIGQDKVKEQLEIFIKAAKMREEVLDHVLLFGP
CCCCCCCCCCCHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGLGKTTMAFVIANELGVNIKQTAGPAIEKPGDLVAILNELEPGDVLFIDEIHRMPMQVE
CCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHCCCCCCEEEHHHHHCCCHHHH
EVLYSAMEDFYIDIMLGSGDGSRSVHLDLPPFTLVGATTRAGMLSNPLRARFGISSHMEY
HHHHHHHHHEEEEEEEECCCCCCEEEEECCCEEEECCCHHCCHHCCCHHHHHCHHHHHHH
YQERDLEEIVKRTADIFEVEVIDNAAMEIALRSRGTPRIANRLLKRVRDFAQIMGDGRVD
HHHCCHHHHHHHHHHHEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
KAITDKALTILDVDAAGLDYIDQKILRTMIEIYHGGPVGIGTLAVNIAEDRETVEDMYEP
HHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEHHEEEEEHHHHHHHHHHHHH
YLIQKGFLMRTKQGRKVTQRAYEHLGYVYNEEE
HHHCCCHHHCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNDILNKEPMEEDYGIEKSLRPQFFNQYIGQDKVKEQLEIFIKAAKMREEVLDHVLLFGP
CCCCCCCCCCCHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGLGKTTMAFVIANELGVNIKQTAGPAIEKPGDLVAILNELEPGDVLFIDEIHRMPMQVE
CCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHCCCCCCEEEHHHHHCCCHHHH
EVLYSAMEDFYIDIMLGSGDGSRSVHLDLPPFTLVGATTRAGMLSNPLRARFGISSHMEY
HHHHHHHHHEEEEEEEECCCCCCEEEEECCCEEEECCCHHCCHHCCCHHHHHCHHHHHHH
YQERDLEEIVKRTADIFEVEVIDNAAMEIALRSRGTPRIANRLLKRVRDFAQIMGDGRVD
HHHCCHHHHHHHHHHHEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
KAITDKALTILDVDAAGLDYIDQKILRTMIEIYHGGPVGIGTLAVNIAEDRETVEDMYEP
HHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEHHEEEEEHHHHHHHHHHHHH
YLIQKGFLMRTKQGRKVTQRAYEHLGYVYNEEE
HHHCCCHHHCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]