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The map label for this gene is gntK [H]

Identifier: 125625224

GI number: 125625224

Start: 2425675

End: 2427183

Strand: Reverse

Name: gntK [H]

Synonym: llmg_2468

Alternate gene names: 125625224

Gene position: 2427183-2425675 (Counterclockwise)

Preceding gene: 125625225

Following gene: 125625223

Centisome position: 95.96

GC content: 39.76

Gene sequence:

>1509_bases
ATGCAATATTTAATAGGCGTAGATTTAGGGACAACGGCGACCAAGGCAGTGCTTTTTGAAAAAGATGGTAAGATTATTGC
AAGTAGTAGTCAAGCCTACCCTCTTCATCGTAATGCTAGTGGAATGGCAGAAGAATCACTTGAAGAAATTTTTGAAGCAG
TCTTAGTAACCATTCGAGAAGTTTCAATTAATTTAGAAGACGAAGACGAACTCTTAGCAGTTTCCTTTAGTACACAAATG
CACTCACTGATTGCTTTTGATGAAAATTGGCAACCACTTACAAGACTAATTACTTGGGCAGACACGAGGGCTGTGAAATA
CACAGAACAAATCAAAGCCTCTAAAAAAGGATTCGATATTTATCGGAGAACAGGAACCCCTCTTCATCCGATGGCTCCTT
TATCTAAATTTATGTGGTTACAAGCGGAATACCCAAGTATCTATCAAAAAGCAGCTCATTACTTGGAGTTGAAAGGTTAC
ATTTTTCAGCGACTTTTCGGAACTAATAAAATTGACTTATCAACGGCAACAGGAACCGGTGTTTTCAATATTTTTGAACT
TCAGTGGGATAAAGAAGCGCTGGAAATGACTGGGATTAAGGAAAGTCAGTTACCAAACGTGGTTGAGCCTTATGAAATTG
AAGAAAATCTTCCGCACGAATATGCAAAAAAAATGGGGATTCAAAGTAGCACCAAATTTATTTGGGGAGCAGCTGATGGA
CCTTTATCAAACTTAGGAGTCAATGCCATCAAACCGGGCGTTGCAGCCATAACTATTGGAACATCTGGGGCCATTCGAGT
GGTGACCGACAGACCAAAAACAGATGAAAAAGGACGTACCTTTACATATGCTTTAGACAGAGAGCATTGGGTAGTGGGTG
GTCCAGTTAATTCTGGAGGTGATGTTTTCCGATGGGCTCGTGACCAGATTTTTGATGGAAAAATCACTTTTGATGAAGTC
ACTGAGCTTGCAGCAAACATTTCACCAGGAGCTGACGGTCTGCTTTTCCATCCTTACCTTGGTGGGGAACGGGCACCGAT
TTGGGATGCTAATGCCAGAGGTTCATTTTTTGGCTTGAATTATGGTCATAACCGAAGTCACATGGCGCATAGCGTTCTTG
AAGGAGTTATTTTTAATATCTATATGGTTGCTCTTAGTCTTGTTGAAGTAGTGGGTGACCTCAACATGATTCAAGCAACA
GGAGGATTCACAAGTTCTGGATTATGGACACAAATTCTTGCAGATATCTTTGAACAACCGATTAATGTTCCTGAAAGTCG
AGAAGCAGGTTGTTTAGCAGCAGTTATTATGGCTGAGAAAGCATTAGGGCTCATTGACGACATTAGTGAAATTGAAAAGA
TGGTAGGGACTAACCAAACTTACCAACCCAATCCAGAAAATTTCAGTATTTATCGAGAAATAAGTCCAATCTTTATCCGA
CTTTCTCGCTCATTTTTAGCAGAATATGAAAATATCGCGAATTTTCAAAGAAAATTTGAAAAAGACTAA

Upstream 100 bases:

>100_bases
GACAGGCGTTTAAGTGCTTAAGCTTCTTGGGTGGTAAGTTCCAGTTTATAATTTGAACTTGGACCTGTCAGCAAATATAT
ATAGAAGAAAAGGAGCGCCA

Downstream 100 bases:

>100_bases
ATTTAGATTCTAAAAAACTCAATACCTACTATACTTAAGATAAAGCAAGTATTGAGTTAAATTTTAAATGCAAATTGTAA
GCGCAAGCAACTGATGTTTA

Product: gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MQYLIGVDLGTTATKAVLFEKDGKIIASSSQAYPLHRNASGMAEESLEEIFEAVLVTIREVSINLEDEDELLAVSFSTQM
HSLIAFDENWQPLTRLITWADTRAVKYTEQIKASKKGFDIYRRTGTPLHPMAPLSKFMWLQAEYPSIYQKAAHYLELKGY
IFQRLFGTNKIDLSTATGTGVFNIFELQWDKEALEMTGIKESQLPNVVEPYEIEENLPHEYAKKMGIQSSTKFIWGAADG
PLSNLGVNAIKPGVAAITIGTSGAIRVVTDRPKTDEKGRTFTYALDREHWVVGGPVNSGGDVFRWARDQIFDGKITFDEV
TELAANISPGADGLLFHPYLGGERAPIWDANARGSFFGLNYGHNRSHMAHSVLEGVIFNIYMVALSLVEVVGDLNMIQAT
GGFTSSGLWTQILADIFEQPINVPESREAGCLAAVIMAEKALGLIDDISEIEKMVGTNQTYQPNPENFSIYREISPIFIR
LSRSFLAEYENIANFQRKFEKD

Sequences:

>Translated_502_residues
MQYLIGVDLGTTATKAVLFEKDGKIIASSSQAYPLHRNASGMAEESLEEIFEAVLVTIREVSINLEDEDELLAVSFSTQM
HSLIAFDENWQPLTRLITWADTRAVKYTEQIKASKKGFDIYRRTGTPLHPMAPLSKFMWLQAEYPSIYQKAAHYLELKGY
IFQRLFGTNKIDLSTATGTGVFNIFELQWDKEALEMTGIKESQLPNVVEPYEIEENLPHEYAKKMGIQSSTKFIWGAADG
PLSNLGVNAIKPGVAAITIGTSGAIRVVTDRPKTDEKGRTFTYALDREHWVVGGPVNSGGDVFRWARDQIFDGKITFDEV
TELAANISPGADGLLFHPYLGGERAPIWDANARGSFFGLNYGHNRSHMAHSVLEGVIFNIYMVALSLVEVVGDLNMIQAT
GGFTSSGLWTQILADIFEQPINVPESREAGCLAAVIMAEKALGLIDDISEIEKMVGTNQTYQPNPENFSIYREISPIFIR
LSRSFLAEYENIANFQRKFEKD
>Mature_502_residues
MQYLIGVDLGTTATKAVLFEKDGKIIASSSQAYPLHRNASGMAEESLEEIFEAVLVTIREVSINLEDEDELLAVSFSTQM
HSLIAFDENWQPLTRLITWADTRAVKYTEQIKASKKGFDIYRRTGTPLHPMAPLSKFMWLQAEYPSIYQKAAHYLELKGY
IFQRLFGTNKIDLSTATGTGVFNIFELQWDKEALEMTGIKESQLPNVVEPYEIEENLPHEYAKKMGIQSSTKFIWGAADG
PLSNLGVNAIKPGVAAITIGTSGAIRVVTDRPKTDEKGRTFTYALDREHWVVGGPVNSGGDVFRWARDQIFDGKITFDEV
TELAANISPGADGLLFHPYLGGERAPIWDANARGSFFGLNYGHNRSHMAHSVLEGVIFNIYMVALSLVEVVGDLNMIQAT
GGFTSSGLWTQILADIFEQPINVPESREAGCLAAVIMAEKALGLIDDISEIEKMVGTNQTYQPNPENFSIYREISPIFIR
LSRSFLAEYENIANFQRKFEKD

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=450, Percent_Identity=26.2222222222222, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI189409120, Length=450, Percent_Identity=26.2222222222222, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI4504007, Length=450, Percent_Identity=26.2222222222222, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI41393575, Length=440, Percent_Identity=26.3636363636364, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI88196792, Length=502, Percent_Identity=21.3147410358566, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI164663828, Length=534, Percent_Identity=20.7865168539326, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI164663830, Length=264, Percent_Identity=23.8636363636364, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789987, Length=486, Percent_Identity=25.3086419753086, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1790005, Length=466, Percent_Identity=25.9656652360515, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1790361, Length=482, Percent_Identity=24.896265560166, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787789, Length=504, Percent_Identity=24.6031746031746, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789168, Length=490, Percent_Identity=21.4285714285714, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17535599, Length=469, Percent_Identity=24.9466950959488, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321755, Length=464, Percent_Identity=26.2931034482759, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24656367, Length=529, Percent_Identity=21.9281663516068, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17864214, Length=397, Percent_Identity=25.1889168765743, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24654573, Length=397, Percent_Identity=25.1889168765743, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21357867, Length=543, Percent_Identity=21.731123388582, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24655555, Length=391, Percent_Identity=24.5524296675192, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24655560, Length=391, Percent_Identity=24.5524296675192, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24655570, Length=391, Percent_Identity=24.5524296675192, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24655574, Length=391, Percent_Identity=24.5524296675192, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24655565, Length=391, Percent_Identity=24.5524296675192, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24656372, Length=378, Percent_Identity=22.4867724867725, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 55952; Mature: 55952

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYLIGVDLGTTATKAVLFEKDGKIIASSSQAYPLHRNASGMAEESLEEIFEAVLVTIRE
CCEEEEECCCCCHHEEEEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VSINLEDEDELLAVSFSTQMHSLIAFDENWQPLTRLITWADTRAVKYTEQIKASKKGFDI
HEECCCCCCCEEEEEECHHHHHHEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEE
YRRTGTPLHPMAPLSKFMWLQAEYPSIYQKAAHYLELKGYIFQRLFGTNKIDLSTATGTG
EECCCCCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
VFNIFELQWDKEALEMTGIKESQLPNVVEPYEIEENLPHEYAKKMGIQSSTKFIWGAADG
EEEEEEEEECHHHHHHCCCCHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCC
PLSNLGVNAIKPGVAAITIGTSGAIRVVTDRPKTDEKGRTFTYALDREHWVVGGPVNSGG
CHHHCCCHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCEEEEECCCCCCC
DVFRWARDQIFDGKITFDEVTELAANISPGADGLLFHPYLGGERAPIWDANARGSFFGLN
CHHHHHHHHHCCCEECHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEECC
YGHNRSHMAHSVLEGVIFNIYMVALSLVEVVGDLNMIQATGGFTSSGLWTQILADIFEQP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCC
INVPESREAGCLAAVIMAEKALGLIDDISEIEKMVGTNQTYQPNPENFSIYREISPIFIR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHH
LSRSFLAEYENIANFQRKFEKD
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQYLIGVDLGTTATKAVLFEKDGKIIASSSQAYPLHRNASGMAEESLEEIFEAVLVTIRE
CCEEEEECCCCCHHEEEEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VSINLEDEDELLAVSFSTQMHSLIAFDENWQPLTRLITWADTRAVKYTEQIKASKKGFDI
HEECCCCCCCEEEEEECHHHHHHEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEE
YRRTGTPLHPMAPLSKFMWLQAEYPSIYQKAAHYLELKGYIFQRLFGTNKIDLSTATGTG
EECCCCCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
VFNIFELQWDKEALEMTGIKESQLPNVVEPYEIEENLPHEYAKKMGIQSSTKFIWGAADG
EEEEEEEEECHHHHHHCCCCHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCC
PLSNLGVNAIKPGVAAITIGTSGAIRVVTDRPKTDEKGRTFTYALDREHWVVGGPVNSGG
CHHHCCCHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCEEEEECCCCCCC
DVFRWARDQIFDGKITFDEVTELAANISPGADGLLFHPYLGGERAPIWDANARGSFFGLN
CHHHHHHHHHCCCEECHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEECC
YGHNRSHMAHSVLEGVIFNIYMVALSLVEVVGDLNMIQATGGFTSSGLWTQILADIFEQP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCC
INVPESREAGCLAAVIMAEKALGLIDDISEIEKMVGTNQTYQPNPENFSIYREISPIFIR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHH
LSRSFLAEYENIANFQRKFEKD
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]