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The map label for this gene is gntP [H]

Identifier: 125625223

GI number: 125625223

Start: 2424123

End: 2425538

Strand: Reverse

Name: gntP [H]

Synonym: llmg_2467

Alternate gene names: 125625223

Gene position: 2425538-2424123 (Counterclockwise)

Preceding gene: 125625224

Following gene: 125625221

Centisome position: 95.89

GC content: 40.18

Gene sequence:

>1416_bases
ATGATTGATTTACTTGTACTTTTAATTGGAGTGTTAATTCTTCTGTTGATGATTATCAAATTTAAGATTAACACCTTTGT
ATCACTAATTGTTGTAGCGGTTCTAGTTGGGTTGGGTCTTGGGATGCCCCTAGGACAAATTCCTGTTTCCATCCAAAACG
GAATAGGAGGATCATTAGGAGAATTAGCAATCGTCTTTGGTTTTGGTGCGATGCTTGGGCGTTTAATTGCTGACGCTGGC
GGTGCCTACCGAATTTCCAAAACTCTCATTAATAGTTTTGGTAAAAAGAGAATTCAATGGGCCATCATGGTTGCCAGTTT
TATCATTGGGATTGCTCTCTTCTTTGAAGTAGGTATGGTTCTATTGATTCCGATTGTCTTTGCCGTTGCCTTGGAAGCCA
GTGTACCTTTGATTTATCTTGGGATTCCGATGGCTGCAGGGCTTTCAGTTACGCATGGCTTCTTGCCACCGCATCCAGCA
CCTATTGCTATTGCTGGTGTACTTGGTGCAAATCCCGGGACAGTTCTACTTTACGGGATAATCGCGGCGATTCCTACAGT
TATTATTGCCGGTCCAGTTTTCACAAAAATTGCTAGAAAATGGGTACCAGAAGCTTTTGTTGTAAAAAATAAACTCTCTG
CTTTTGGTGAAATAAAAGAGTGGAAACTTGAAGAAACACCAGGCTTTGGAATATCTATCTTGACAGCTCTTATGCCAGTA
ATTTTAATGGCAATTAGTACAGTTTATTCTATTGCGGCTAATGATGGGAAACCCTTTGCCGCAGTAACGACAAGTGCGAT
GAAAGCTGGTAAAGTAGTTACGACGACGACTTATCCTTCAAGTATTGTTGAAAATGTGATGATGTTCATCGGAAATCCAG
TGTCAGCAATGATTATTTCTCTGCTCTTTACCTTAGTCACTATGGGTTGGATGCGCCGTAAGAAAAATTCTGAAATTGCT
TCTTCAATTGCGGATTCAGTTAAATCAATTGCCATGCTTTTATTAGTCATTGGTGGAGGAGCAGCGCTCAAACAAATTCT
TATTGATGGTGGAATCTCAGTTCAAATCGCTAATATGTTTAAAGATTCACCCCTTTCTCCTTTATTGCTTGCTTGGATTA
TCACGGTTATCTTAAGGGTTGCATTGGGATCAGCGACAGTGGCTGCCCTAACAGCAGCAGGTCTAGTTCAACCAATGCTT
GCTACAGCATCTCCAAATACAGCAGCTTTGATGGTTTTGGCAATAGGTGCCGGTTCAATTGCAGCTTCACATGTTAATGA
TGCTGGATTCTGGATGTTTAAAGAGTATTTTGATTTAGATGTGAAACAAACCTTAAAAACATGGACAGTCTTAGAAACAA
TTATCGCAGTAGTAGGTTTAGGAATGGTAATGTTGATGAGTATTTGGATTCACTGA

Upstream 100 bases:

>100_bases
AAGATAAAGCAAGTATTGAGTTAAATTTTAAATGCAAATTGTAAGCGCAAGCAACTGATGTTTACACAATGTCTTCAAGA
TTTTTGAAAGGAAAAAACAA

Downstream 100 bases:

>100_bases
TAAAAAATAAGTCATTTTTTGACTTATTTTTTTTATTTTCTCTAAGTCAGTGGTAGCAAACGATAAAACGCTATCAAAGT
TCGTTAAAACGAACAAAAGG

Product: gluconate transport protein

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MIDLLVLLIGVLILLLMIIKFKINTFVSLIVVAVLVGLGLGMPLGQIPVSIQNGIGGSLGELAIVFGFGAMLGRLIADAG
GAYRISKTLINSFGKKRIQWAIMVASFIIGIALFFEVGMVLLIPIVFAVALEASVPLIYLGIPMAAGLSVTHGFLPPHPA
PIAIAGVLGANPGTVLLYGIIAAIPTVIIAGPVFTKIARKWVPEAFVVKNKLSAFGEIKEWKLEETPGFGISILTALMPV
ILMAISTVYSIAANDGKPFAAVTTSAMKAGKVVTTTTYPSSIVENVMMFIGNPVSAMIISLLFTLVTMGWMRRKKNSEIA
SSIADSVKSIAMLLLVIGGGAALKQILIDGGISVQIANMFKDSPLSPLLLAWIITVILRVALGSATVAALTAAGLVQPML
ATASPNTAALMVLAIGAGSIAASHVNDAGFWMFKEYFDLDVKQTLKTWTVLETIIAVVGLGMVMLMSIWIH

Sequences:

>Translated_471_residues
MIDLLVLLIGVLILLLMIIKFKINTFVSLIVVAVLVGLGLGMPLGQIPVSIQNGIGGSLGELAIVFGFGAMLGRLIADAG
GAYRISKTLINSFGKKRIQWAIMVASFIIGIALFFEVGMVLLIPIVFAVALEASVPLIYLGIPMAAGLSVTHGFLPPHPA
PIAIAGVLGANPGTVLLYGIIAAIPTVIIAGPVFTKIARKWVPEAFVVKNKLSAFGEIKEWKLEETPGFGISILTALMPV
ILMAISTVYSIAANDGKPFAAVTTSAMKAGKVVTTTTYPSSIVENVMMFIGNPVSAMIISLLFTLVTMGWMRRKKNSEIA
SSIADSVKSIAMLLLVIGGGAALKQILIDGGISVQIANMFKDSPLSPLLLAWIITVILRVALGSATVAALTAAGLVQPML
ATASPNTAALMVLAIGAGSIAASHVNDAGFWMFKEYFDLDVKQTLKTWTVLETIIAVVGLGMVMLMSIWIH
>Mature_471_residues
MIDLLVLLIGVLILLLMIIKFKINTFVSLIVVAVLVGLGLGMPLGQIPVSIQNGIGGSLGELAIVFGFGAMLGRLIADAG
GAYRISKTLINSFGKKRIQWAIMVASFIIGIALFFEVGMVLLIPIVFAVALEASVPLIYLGIPMAAGLSVTHGFLPPHPA
PIAIAGVLGANPGTVLLYGIIAAIPTVIIAGPVFTKIARKWVPEAFVVKNKLSAFGEIKEWKLEETPGFGISILTALMPV
ILMAISTVYSIAANDGKPFAAVTTSAMKAGKVVTTTTYPSSIVENVMMFIGNPVSAMIISLLFTLVTMGWMRRKKNSEIA
SSIADSVKSIAMLLLVIGGGAALKQILIDGGISVQIANMFKDSPLSPLLLAWIITVILRVALGSATVAALTAAGLVQPML
ATASPNTAALMVLAIGAGSIAASHVNDAGFWMFKEYFDLDVKQTLKTWTVLETIIAVVGLGMVMLMSIWIH

Specific function: Part Of The Gluconate Utilization System Gnt-I; High- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=472, Percent_Identity=47.2457627118644, Blast_Score=413, Evalue=1e-116,
Organism=Escherichia coli, GI1790716, Length=471, Percent_Identity=45.2229299363057, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI2367370, Length=445, Percent_Identity=46.2921348314607, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1790776, Length=474, Percent_Identity=36.2869198312236, Blast_Score=284, Evalue=1e-77,
Organism=Escherichia coli, GI1788707, Length=470, Percent_Identity=33.6170212765957, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI48994939, Length=453, Percent_Identity=33.112582781457, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1789097, Length=466, Percent_Identity=33.6909871244635, Blast_Score=211, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 49464; Mature: 49464

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLLVLLIGVLILLLMIIKFKINTFVSLIVVAVLVGLGLGMPLGQIPVSIQNGIGGSLG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHH
ELAIVFGFGAMLGRLIADAGGAYRISKTLINSFGKKRIQWAIMVASFIIGIALFFEVGMV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIPIVFAVALEASVPLIYLGIPMAAGLSVTHGFLPPHPAPIAIAGVLGANPGTVLLYGI
HHHHHHHHHHHHCCCCEEEECCCHHCCCHHHCCCCCCCCCCEEEEEHHCCCCCHHHHHHH
IAAIPTVIIAGPVFTKIARKWVPEAFVVKNKLSAFGEIKEWKLEETPGFGISILTALMPV
HHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHH
ILMAISTVYSIAANDGKPFAAVTTSAMKAGKVVTTTTYPSSIVENVMMFIGNPVSAMIIS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHH
LLFTLVTMGWMRRKKNSEIASSIADSVKSIAMLLLVIGGGAALKQILIDGGISVQIANMF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEHHHH
KDSPLSPLLLAWIITVILRVALGSATVAALTAAGLVQPMLATASPNTAALMVLAIGAGSI
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEECCCHH
AASHVNDAGFWMFKEYFDLDVKQTLKTWTVLETIIAVVGLGMVMLMSIWIH
HHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDLLVLLIGVLILLLMIIKFKINTFVSLIVVAVLVGLGLGMPLGQIPVSIQNGIGGSLG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHH
ELAIVFGFGAMLGRLIADAGGAYRISKTLINSFGKKRIQWAIMVASFIIGIALFFEVGMV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIPIVFAVALEASVPLIYLGIPMAAGLSVTHGFLPPHPAPIAIAGVLGANPGTVLLYGI
HHHHHHHHHHHHCCCCEEEECCCHHCCCHHHCCCCCCCCCCEEEEEHHCCCCCHHHHHHH
IAAIPTVIIAGPVFTKIARKWVPEAFVVKNKLSAFGEIKEWKLEETPGFGISILTALMPV
HHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHH
ILMAISTVYSIAANDGKPFAAVTTSAMKAGKVVTTTTYPSSIVENVMMFIGNPVSAMIIS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHH
LLFTLVTMGWMRRKKNSEIASSIADSVKSIAMLLLVIGGGAALKQILIDGGISVQIANMF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEHHHH
KDSPLSPLLLAWIITVILRVALGSATVAALTAAGLVQPMLATASPNTAALMVLAIGAGSI
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEECCCHH
AASHVNDAGFWMFKEYFDLDVKQTLKTWTVLETIIAVVGLGMVMLMSIWIH
HHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]