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The map label for this gene is rlrB [H]

Identifier: 125624839

GI number: 125624839

Start: 2050435

End: 2051313

Strand: Reverse

Name: rlrB [H]

Synonym: llmg_2067

Alternate gene names: 125624839

Gene position: 2051313-2050435 (Counterclockwise)

Preceding gene: 125624840

Following gene: 125624838

Centisome position: 81.1

GC content: 37.32

Gene sequence:

>879_bases
ATGGAACTTCGATTATTAAAGTATTTTTGGACAGTTGCCACTGCTGGGACGGTATCCAAAGCTGCTGAGCAGTTATATAT
TACACAGCCAACATTATCTAGACAAATTAAAGAACTTGAACGAGAATTAGATACTCAGCTTTTTATGCGTGATGGGAAAA
AGCTTATCTTGACTGAAGATGGTCAATTTCTTAAAATCAAAGCTGAAGAGATTTTACAGCTGACGAGTAAAACAGTCCAA
GTTTTTGAAGACCGGAAAAATGCGGAATTATCAGGACATTTGACAATTGGAGCCTTAGAAGGATGGACAAGTTCCAGCAT
TGCTAAAACACTTCAAACACTCACAAATAAGTATCCTGCCATCACTTTTACAATCTTGTCAGGAAATGCAGATGACATCA
AATGGAAGATTGATAATGGACTTGTGGATGTCGGATTTTTGTTAGAGCCAACGTCTACAGAAAAATATAATGTAGAAAAA
ATTGGCTTTCCTGAGCGTTGGATGATGCTCACACAATCCGATTCAGAACTTGCAGAATTAGATGAAGTAAGGCCAGAAGT
ATTTAAAAAACAACGAATTTTGATTTCAGAACGACCAGAAGTTCGTCAGTATATGGCTGATTGGGCGGACTGCCAAGTGA
GTGATTTAAATATTATTGGGGGCTTCAATCTTGGATTTCATCTTTTTGAGATTGCTCGTGCAGGAATTGGTGAGGCAGTC
GTTACAGAAGGTGCACTCATTAGAAATTATCCAGATTTAAAAGCGATTCCCTTAAGTCCAGAAGTGAAGACATATAGCGT
TCTTGCTTGGAAGAAAAATATTCCATTGACACCAGTCACTAGAGCATTTATCAAACAATACTTACAAGAAAATGATTAA

Upstream 100 bases:

>100_bases
ATTCAAAATTGAAAATTATGATGAAGTCATGCTTCCAAGCGAAATGAATTTGAATCAAAGTTCAACAGAAGCAATAAAAA
TTTGAAGAGGATAAGGATAA

Downstream 100 bases:

>100_bases
AAATTTACTGACCAATCTGTCAGTAAATTTTTTATTTTTTAATATGCTTTATAAGCATAATTAATACTAAAATAAGCATT
TTTCATCAGTTGATTTTTGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MELRLLKYFWTVATAGTVSKAAEQLYITQPTLSRQIKELERELDTQLFMRDGKKLILTEDGQFLKIKAEEILQLTSKTVQ
VFEDRKNAELSGHLTIGALEGWTSSSIAKTLQTLTNKYPAITFTILSGNADDIKWKIDNGLVDVGFLLEPTSTEKYNVEK
IGFPERWMMLTQSDSELAELDEVRPEVFKKQRILISERPEVRQYMADWADCQVSDLNIIGGFNLGFHLFEIARAGIGEAV
VTEGALIRNYPDLKAIPLSPEVKTYSVLAWKKNIPLTPVTRAFIKQYLQEND

Sequences:

>Translated_292_residues
MELRLLKYFWTVATAGTVSKAAEQLYITQPTLSRQIKELERELDTQLFMRDGKKLILTEDGQFLKIKAEEILQLTSKTVQ
VFEDRKNAELSGHLTIGALEGWTSSSIAKTLQTLTNKYPAITFTILSGNADDIKWKIDNGLVDVGFLLEPTSTEKYNVEK
IGFPERWMMLTQSDSELAELDEVRPEVFKKQRILISERPEVRQYMADWADCQVSDLNIIGGFNLGFHLFEIARAGIGEAV
VTEGALIRNYPDLKAIPLSPEVKTYSVLAWKKNIPLTPVTRAFIKQYLQEND
>Mature_292_residues
MELRLLKYFWTVATAGTVSKAAEQLYITQPTLSRQIKELERELDTQLFMRDGKKLILTEDGQFLKIKAEEILQLTSKTVQ
VFEDRKNAELSGHLTIGALEGWTSSSIAKTLQTLTNKYPAITFTILSGNADDIKWKIDNGLVDVGFLLEPTSTEKYNVEK
IGFPERWMMLTQSDSELAELDEVRPEVFKKQRILISERPEVRQYMADWADCQVSDLNIIGGFNLGFHLFEIARAGIGEAV
VTEGALIRNYPDLKAIPLSPEVKTYSVLAWKKNIPLTPVTRAFIKQYLQEND

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=291, Percent_Identity=25.4295532646048, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788297, Length=253, Percent_Identity=25.6916996047431, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788748, Length=287, Percent_Identity=25.7839721254355, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788887, Length=292, Percent_Identity=27.0547945205479, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790208, Length=150, Percent_Identity=29.3333333333333, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788296, Length=178, Percent_Identity=28.6516853932584, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787806, Length=288, Percent_Identity=21.875, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788481, Length=158, Percent_Identity=28.4810126582279, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787879, Length=303, Percent_Identity=24.7524752475248, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87082132, Length=197, Percent_Identity=24.8730964467005, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790399, Length=147, Percent_Identity=25.8503401360544, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788706, Length=128, Percent_Identity=31.25, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789173, Length=161, Percent_Identity=32.2981366459627, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33180; Mature: 33180

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRLLKYFWTVATAGTVSKAAEQLYITQPTLSRQIKELERELDTQLFMRDGKKLILTED
CCEEHHHHHHHHHCCCHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GQFLKIKAEEILQLTSKTVQVFEDRKNAELSGHLTIGALEGWTSSSIAKTLQTLTNKYPA
CCEEEEEHHHHHHHHHHHHHHHHCCCCCCEECEEEEEEECCCCHHHHHHHHHHHHCCCCE
ITFTILSGNADDIKWKIDNGLVDVGFLLEPTSTEKYNVEKIGFPERWMMLTQSDSELAEL
EEEEEEECCCCCEEEEECCCEEEEEEEECCCCCCCCCEEECCCCHHEEEEECCCHHHHHH
DEVRPEVFKKQRILISERPEVRQYMADWADCQVSDLNIIGGFNLGFHLFEIARAGIGEAV
HHHCHHHHHHHHHEECCCHHHHHHHHHHCCCEEECEEEEECCCHHHHHHHHHHCCCCHHH
VTEGALIRNYPDLKAIPLSPEVKTYSVLAWKKNIPLTPVTRAFIKQYLQEND
HHCCHHCCCCCCCEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELRLLKYFWTVATAGTVSKAAEQLYITQPTLSRQIKELERELDTQLFMRDGKKLILTED
CCEEHHHHHHHHHCCCHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GQFLKIKAEEILQLTSKTVQVFEDRKNAELSGHLTIGALEGWTSSSIAKTLQTLTNKYPA
CCEEEEEHHHHHHHHHHHHHHHHCCCCCCEECEEEEEEECCCCHHHHHHHHHHHHCCCCE
ITFTILSGNADDIKWKIDNGLVDVGFLLEPTSTEKYNVEKIGFPERWMMLTQSDSELAEL
EEEEEEECCCCCEEEEECCCEEEEEEEECCCCCCCCCEEECCCCHHEEEEECCCHHHHHH
DEVRPEVFKKQRILISERPEVRQYMADWADCQVSDLNIIGGFNLGFHLFEIARAGIGEAV
HHHCHHHHHHHHHEECCCHHHHHHHHHHCCCEEECEEEEECCCHHHHHHHHHHCCCCHHH
VTEGALIRNYPDLKAIPLSPEVKTYSVLAWKKNIPLTPVTRAFIKQYLQEND
HHCCHHCCCCCCCEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]