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The map label for this gene is atpA [H]

Identifier: 125624727

GI number: 125624727

Start: 1929984

End: 1931486

Strand: Reverse

Name: atpA [H]

Synonym: llmg_1948

Alternate gene names: 125624727

Gene position: 1931486-1929984 (Counterclockwise)

Preceding gene: 125624728

Following gene: 125624726

Centisome position: 76.36

GC content: 41.12

Gene sequence:

>1503_bases
TTGGCAATTAAAGCTAATGAAATCAGCTCACTGATTAAAAAACAAATTGAAAATTTCACACCAGATTTTGAAGTTGCTGA
AACTGGTGTCGTTACCTATGTTGGTGATGGTATCGCGCGTGCCTATGGCCTTGAAAATGCGATGAGCGGTGAGCTTGTTG
AGTTTTCAAATGGTATACTTGGTATGGCGCAAAACTTGGATGCTACAGACGTTGGTATTATCGTACTTGGTGATTTCCTC
TCAATTCGTGAAGGTGACACTGTTAAACGTACAGGTAAAATCATGGAAATCCAAGTTGGTGAAGAACTCATCGGACGTGT
TGTAAACCCACTTGGACAACCCGTTGATGGACTTGGAGAACTTAATACAGGTAAAACTCGTCCAGTTGAAGCAAAAGCTC
CTGGTGTTATGCAACGTAAATCAGTCTCTGAGCCATTACAAACTGGTCTTAAAGCGATTGATGCCCTCGTTCCAATTGGA
CGTGGACAACGTGAATTAATTATCGGAGACCGTCAAACTGGTAAAACTTCAGTCGCTATTGATGCAATCTTGAACCAAAA
AGGTCAAGATATGATTTGTATCTATGTTGCGATTGGACAAAAAGAGTCAACAGTTCGTACACAAGTTGAAACGCTCCGTA
AACTCGGTGCGATGGATTATACTATCGTCGTAACTGCGTCAGCTTCTCAACCTTCTCCACTCCTTTACATCGCTCCTTAC
GCTGGAGCTGCAATGGGTGAAGAATTTATGTATAACGGTAAACATGTCTTGGTTGTTTATGATGATTTATCTAAACAAGC
GGTCGCTTACCGTGAACTTTCTCTCTTGCTCCGTCGTCCACCAGGTCGTGAAGCATACCCAGGTGACGTTTTCTACTTGC
ACTCACGTCTTTTGGAACGTGCTGCTAAATTGTCTGATGATCTTGGTGGTGGATCAATGACGGCTTTGCCATTCATTGAA
ACACAAGCAGGTGATATCTCAGCTTATATTGCAACAAACGTTATCTCTATTACCGACGGTCAAATTTTCCTTGAAAATGA
CTTGTTCTATTCAGGTGTACGTCCTGCCATTGATGCTGGTTCATCAGTATCACGTGTTGGTGGTGCCGCACAAATCAAAG
CCATGAAGAAAGTAGCTGGTACTTTGCGTCTTGACCTTGCGTCGTTCCGTGAACTTGAAGCCTTTACACAATTTGGTTCT
GACCTTGATGAAGCGACTCAAGCAAAATTGAATCGTGGTCGTCGTACCGTTGAAGTCTTGAAACAACCATTGCACAAACC
ATTGGCTGTTGAAAAACAAGTTTTGATTCTCTATGCATTGACTCATGGTCATCTTGATAATGTTCCAGTTGATGATGTTC
TTGATTTTGAAACTAAAATGTTCGATTTCTTCGATGCAAATTATGCAGATCTCTTGAACGTAATTACTGACACTAAAGAT
TTGCCAGAAGAAGCAAAACTTGACGAAGCAATTAAAGCATTCAAAAATACAACGAATTATTAA

Upstream 100 bases:

>100_bases
GTAATTTTAAAACTTGCTTATTCATGCTCAAAAAGTATAACTGCAGTTTAAAGCTAAATAGCCTTGAACTAGTAAAAAAT
TTCTAGAAGGGAGCATATTT

Downstream 100 bases:

>100_bases
TAAGGAGGCTAACTAATGGGAGCTTCACTTAACGAAATAAAAACTAAGATTGCGTCAACAAAGAAAACAAGTCAAATCAC
AGGTGCCATGCAAATGGTTT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MAIKANEISSLIKKQIENFTPDFEVAETGVVTYVGDGIARAYGLENAMSGELVEFSNGILGMAQNLDATDVGIIVLGDFL
SIREGDTVKRTGKIMEIQVGEELIGRVVNPLGQPVDGLGELNTGKTRPVEAKAPGVMQRKSVSEPLQTGLKAIDALVPIG
RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRKLGAMDYTIVVTASASQPSPLLYIAPY
AGAAMGEEFMYNGKHVLVVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFIE
TQAGDISAYIATNVISITDGQIFLENDLFYSGVRPAIDAGSSVSRVGGAAQIKAMKKVAGTLRLDLASFRELEAFTQFGS
DLDEATQAKLNRGRRTVEVLKQPLHKPLAVEKQVLILYALTHGHLDNVPVDDVLDFETKMFDFFDANYADLLNVITDTKD
LPEEAKLDEAIKAFKNTTNY

Sequences:

>Translated_500_residues
MAIKANEISSLIKKQIENFTPDFEVAETGVVTYVGDGIARAYGLENAMSGELVEFSNGILGMAQNLDATDVGIIVLGDFL
SIREGDTVKRTGKIMEIQVGEELIGRVVNPLGQPVDGLGELNTGKTRPVEAKAPGVMQRKSVSEPLQTGLKAIDALVPIG
RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRKLGAMDYTIVVTASASQPSPLLYIAPY
AGAAMGEEFMYNGKHVLVVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFIE
TQAGDISAYIATNVISITDGQIFLENDLFYSGVRPAIDAGSSVSRVGGAAQIKAMKKVAGTLRLDLASFRELEAFTQFGS
DLDEATQAKLNRGRRTVEVLKQPLHKPLAVEKQVLILYALTHGHLDNVPVDDVLDFETKMFDFFDANYADLLNVITDTKD
LPEEAKLDEAIKAFKNTTNY
>Mature_499_residues
AIKANEISSLIKKQIENFTPDFEVAETGVVTYVGDGIARAYGLENAMSGELVEFSNGILGMAQNLDATDVGIIVLGDFLS
IREGDTVKRTGKIMEIQVGEELIGRVVNPLGQPVDGLGELNTGKTRPVEAKAPGVMQRKSVSEPLQTGLKAIDALVPIGR
GQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRKLGAMDYTIVVTASASQPSPLLYIAPYA
GAAMGEEFMYNGKHVLVVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFIET
QAGDISAYIATNVISITDGQIFLENDLFYSGVRPAIDAGSSVSRVGGAAQIKAMKKVAGTLRLDLASFRELEAFTQFGSD
LDEATQAKLNRGRRTVEVLKQPLHKPLAVEKQVLILYALTHGHLDNVPVDDVLDFETKMFDFFDANYADLLNVITDTKDL
PEEAKLDEAIKAFKNTTNY

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=498, Percent_Identity=58.2329317269076, Blast_Score=574, Evalue=1e-164,
Organism=Homo sapiens, GI4757810, Length=498, Percent_Identity=58.2329317269076, Blast_Score=574, Evalue=1e-164,
Organism=Homo sapiens, GI19913426, Length=305, Percent_Identity=27.2131147540984, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI19913428, Length=305, Percent_Identity=26.8852459016393, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI32189394, Length=383, Percent_Identity=24.8041775456919, Blast_Score=90, Evalue=5e-18,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=51.4619883040936, Blast_Score=523, Evalue=1e-150,
Organism=Escherichia coli, GI1788251, Length=272, Percent_Identity=33.0882352941176, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790170, Length=406, Percent_Identity=24.384236453202, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=57.7689243027888, Blast_Score=574, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=57.7689243027888, Blast_Score=573, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=53.9840637450199, Blast_Score=522, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17510931, Length=357, Percent_Identity=26.3305322128852, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17570191, Length=299, Percent_Identity=27.0903010033445, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144756, Length=415, Percent_Identity=23.6144578313253, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71988068, Length=74, Percent_Identity=44.5945945945946, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=504, Percent_Identity=56.7460317460317, Blast_Score=573, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6319603, Length=305, Percent_Identity=26.8852459016393, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322581, Length=412, Percent_Identity=24.0291262135922, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24658560, Length=504, Percent_Identity=57.5396825396825, Blast_Score=577, Evalue=1e-165,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=26.578073089701, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=26.578073089701, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=26.578073089701, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24638766, Length=415, Percent_Identity=24.3373493975904, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28574560, Length=427, Percent_Identity=23.6533957845433, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI20129479, Length=259, Percent_Identity=27.7992277992278, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54311; Mature: 54180

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKANEISSLIKKQIENFTPDFEVAETGVVTYVGDGIARAYGLENAMSGELVEFSNGIL
CCCCHHHHHHHHHHHHHHCCCCCCHHCCCEEEEECCHHHHHHCCCCCCCCCCEECCCCCE
GMAQNLDATDVGIIVLGDFLSIREGDTVKRTGKIMEIQVGEELIGRVVNPLGQPVDGLGE
EHHCCCCCCCEEEEEEECHHHCCCCCCHHHCCCEEEEECCHHHHHHHHHHCCCCCCCCCC
LNTGKTRPVEAKAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
DAILNQKGQDMICIYVAIGQKESTVRTQVETLRKLGAMDYTIVVTASASQPSPLLYIAPY
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCC
AGAAMGEEFMYNGKHVLVVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCCHHCHHHEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLSDDLGGGSMTALPFIETQAGDISAYIATNVISITDGQIFLENDLFYSGVRPAIDAG
HHHHCCCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCEEEEECCCEECCCCHHHCCC
SSVSRVGGAAQIKAMKKVAGTLRLDLASFRELEAFTQFGSDLDEATQAKLNRGRRTVEVL
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHH
KQPLHKPLAVEKQVLILYALTHGHLDNVPVDDVLDFETKMFDFFDANYADLLNVITDTKD
HHHCCCCHHHCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
LPEEAKLDEAIKAFKNTTNY
CCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AIKANEISSLIKKQIENFTPDFEVAETGVVTYVGDGIARAYGLENAMSGELVEFSNGIL
CCCHHHHHHHHHHHHHHCCCCCCHHCCCEEEEECCHHHHHHCCCCCCCCCCEECCCCCE
GMAQNLDATDVGIIVLGDFLSIREGDTVKRTGKIMEIQVGEELIGRVVNPLGQPVDGLGE
EHHCCCCCCCEEEEEEECHHHCCCCCCHHHCCCEEEEECCHHHHHHHHHHCCCCCCCCCC
LNTGKTRPVEAKAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
DAILNQKGQDMICIYVAIGQKESTVRTQVETLRKLGAMDYTIVVTASASQPSPLLYIAPY
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCC
AGAAMGEEFMYNGKHVLVVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCCHHCHHHEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLSDDLGGGSMTALPFIETQAGDISAYIATNVISITDGQIFLENDLFYSGVRPAIDAG
HHHHCCCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCEEEEECCCEECCCCHHHCCC
SSVSRVGGAAQIKAMKKVAGTLRLDLASFRELEAFTQFGSDLDEATQAKLNRGRRTVEVL
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHH
KQPLHKPLAVEKQVLILYALTHGHLDNVPVDDVLDFETKMFDFFDANYADLLNVITDTKD
HHHCCCCHHHCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
LPEEAKLDEAIKAFKNTTNY
CCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]