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The map label for this gene is aroB [H]

Identifier: 125624718

GI number: 125624718

Start: 1918746

End: 1919816

Strand: Reverse

Name: aroB [H]

Synonym: llmg_1938

Alternate gene names: 125624718

Gene position: 1919816-1918746 (Counterclockwise)

Preceding gene: 125624719

Following gene: 125624717

Centisome position: 75.9

GC content: 38.84

Gene sequence:

>1071_bases
ATGAAATTAAATGTAAATCTACCAGACCATCCCTATGATGTCATCATTGAAAATGGGGCTTTGGCTAATATAGGAAATTG
GGTTTCATCATTGTGGAAAAAGCAAAAAATTGTCTTGATTTCGGATAATCATGTCAACGGGCTTTATGGTCAGAAAGTTG
TTGACCAACTTGAAAAATCAGGTTTTGAAGTAGAAACTTTTGAATTTCCAGAGGGTGAAGCCAGTAAAAATTTACTGACA
GCCGAAAAAGCTTGGAATTTTTGTGCTGAGTTTGGACTGACACGTTCTGACGGAATTATTGCACTCGGTGGTGGAGTGAC
AGGTGATTTAGCTGGTTTTGTAGCTTCTACTTATATGCGTGGCATTCATTTCTTACAAATTCCAACCAGTTTAACCGCGC
AAGTTGATAGTTCTATTGGCGGGAAAACAGGGATTAACTCTAAAATGGCTAAAAATATGATTGGGACTTTTACACAACCA
GATGGGGTGCTGATTGACCCAGAAGTTCTGAAAACATTAGGTCAAAGAGAGTTTTGTGAAGGCTTGGGAGAAGTCATTAA
ATGTGCCCTAATTGCTGATAAAGACCTGTGGAATTTACTGACAGACCTGTCAGCCAAAGATTTGCTGGAAAATTTTGCAA
AAATTGAAGAAATTATTTATCGGTCTTGTGAAGTAAAACGAAAAGTGGTTGTTGATGATGAGCTTGATAATGGCGTGCGG
CTTTATCTAAATTTTGGACATACGATTGGGCATGCTGTCGAAAATACGGCGGGTTATGGAAAAGTCATGCACGGCGAAGC
CGTTGCCATTGGGATGGTACAAATCAGTAAAATTGCTGAGAAAAAAGGTCTCATGCCTCTCGGAATTACTGATGAAATCC
GAAAGATGGTCAAAAAATATGGTTTGCCTGATGACTATCAACCTTGGGACGAGGCGCTTTTGTTTAAAGCGCTCACTCAC
GATAAAAAAGCGCGTGGAACAATCATCAAAACAGTTATTGTCCCTGAAATTGGCACTGCCAAAATCAATGAAGTGACTTT
TGAAGAAATGAAAGAATATCTCAAAAAATAA

Upstream 100 bases:

>100_bases
GGCTCGGTATGCTCATTGGACAGGCGGCGGAAAGCTTTTATTTATGGACAGGCAAAGAAATGCCTGTGGACAAAATTACA
TTAGAAATGGAGAGAGAAGT

Downstream 100 bases:

>100_bases
GTTGATTCGATTGAAAGAGAAAATCTTTCTAAAAAATACAAAATGTGGTAGCATTGAAAAACTCCCAGCTTAGATAAAAA
AGCTGTTAAAACACTTAATT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKLNVNLPDHPYDVIIENGALANIGNWVSSLWKKQKIVLISDNHVNGLYGQKVVDQLEKSGFEVETFEFPEGEASKNLLT
AEKAWNFCAEFGLTRSDGIIALGGGVTGDLAGFVASTYMRGIHFLQIPTSLTAQVDSSIGGKTGINSKMAKNMIGTFTQP
DGVLIDPEVLKTLGQREFCEGLGEVIKCALIADKDLWNLLTDLSAKDLLENFAKIEEIIYRSCEVKRKVVVDDELDNGVR
LYLNFGHTIGHAVENTAGYGKVMHGEAVAIGMVQISKIAEKKGLMPLGITDEIRKMVKKYGLPDDYQPWDEALLFKALTH
DKKARGTIIKTVIVPEIGTAKINEVTFEEMKEYLKK

Sequences:

>Translated_356_residues
MKLNVNLPDHPYDVIIENGALANIGNWVSSLWKKQKIVLISDNHVNGLYGQKVVDQLEKSGFEVETFEFPEGEASKNLLT
AEKAWNFCAEFGLTRSDGIIALGGGVTGDLAGFVASTYMRGIHFLQIPTSLTAQVDSSIGGKTGINSKMAKNMIGTFTQP
DGVLIDPEVLKTLGQREFCEGLGEVIKCALIADKDLWNLLTDLSAKDLLENFAKIEEIIYRSCEVKRKVVVDDELDNGVR
LYLNFGHTIGHAVENTAGYGKVMHGEAVAIGMVQISKIAEKKGLMPLGITDEIRKMVKKYGLPDDYQPWDEALLFKALTH
DKKARGTIIKTVIVPEIGTAKINEVTFEEMKEYLKK
>Mature_356_residues
MKLNVNLPDHPYDVIIENGALANIGNWVSSLWKKQKIVLISDNHVNGLYGQKVVDQLEKSGFEVETFEFPEGEASKNLLT
AEKAWNFCAEFGLTRSDGIIALGGGVTGDLAGFVASTYMRGIHFLQIPTSLTAQVDSSIGGKTGINSKMAKNMIGTFTQP
DGVLIDPEVLKTLGQREFCEGLGEVIKCALIADKDLWNLLTDLSAKDLLENFAKIEEIIYRSCEVKRKVVVDDELDNGVR
LYLNFGHTIGHAVENTAGYGKVMHGEAVAIGMVQISKIAEKKGLMPLGITDEIRKMVKKYGLPDDYQPWDEALLFKALTH
DKKARGTIIKTVIVPEIGTAKINEVTFEEMKEYLKK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=350, Percent_Identity=35.4285714285714, Blast_Score=209, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6320332, Length=343, Percent_Identity=35.2769679300292, Blast_Score=182, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39266; Mature: 39266

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNVNLPDHPYDVIIENGALANIGNWVSSLWKKQKIVLISDNHVNGLYGQKVVDQLEKS
CEEECCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHC
GFEVETFEFPEGEASKNLLTAEKAWNFCAEFGLTRSDGIIALGGGVTGDLAGFVASTYMR
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHC
GIHFLQIPTSLTAQVDSSIGGKTGINSKMAKNMIGTFTQPDGVLIDPEVLKTLGQREFCE
CEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCEEECHHHHHHCCHHHHHH
GLGEVIKCALIADKDLWNLLTDLSAKDLLENFAKIEEIIYRSCEVKRKVVVDDELDNGVR
HHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEE
LYLNFGHTIGHAVENTAGYGKVMHGEAVAIGMVQISKIAEKKGLMPLGITDEIRKMVKKY
EEEECCCHHHHHHHCCCCCCEEECCCEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
GLPDDYQPWDEALLFKALTHDKKARGTIIKTVIVPEIGTAKINEVTFEEMKEYLKK
CCCCCCCCHHHHHHHHHHHCCCHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLNVNLPDHPYDVIIENGALANIGNWVSSLWKKQKIVLISDNHVNGLYGQKVVDQLEKS
CEEECCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHC
GFEVETFEFPEGEASKNLLTAEKAWNFCAEFGLTRSDGIIALGGGVTGDLAGFVASTYMR
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHC
GIHFLQIPTSLTAQVDSSIGGKTGINSKMAKNMIGTFTQPDGVLIDPEVLKTLGQREFCE
CEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCEEECHHHHHHCCHHHHHH
GLGEVIKCALIADKDLWNLLTDLSAKDLLENFAKIEEIIYRSCEVKRKVVVDDELDNGVR
HHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEE
LYLNFGHTIGHAVENTAGYGKVMHGEAVAIGMVQISKIAEKKGLMPLGITDEIRKMVKKY
EEEECCCHHHHHHHCCCCCCEEECCCEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
GLPDDYQPWDEALLFKALTHDKKARGTIIKTVIVPEIGTAKINEVTFEEMKEYLKK
CCCCCCCCHHHHHHHHHHHCCCHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]