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The map label for this gene is xseA [H]

Identifier: 125624489

GI number: 125624489

Start: 1666467

End: 1667720

Strand: Reverse

Name: xseA [H]

Synonym: llmg_1692

Alternate gene names: 125624489

Gene position: 1667720-1666467 (Counterclockwise)

Preceding gene: 125624490

Following gene: 125624488

Centisome position: 65.93

GC content: 38.28

Gene sequence:

>1254_bases
ATGACAGAATATTTATCAGTATCAACCTTAACAAAATATTTGAAAGCAAAATTTGAACGAGACCCTTATCTTGAGCGCGT
GTATTTGACAGGGGAAATTTCAAATTTTAGAAGAAGACCTAATCATCAGTATTTTGCTCTTAAAGATGAAGGGGCTGTGA
TTCAAGCGACGATGTGGGCAGGGCAATTTCGTAAGTTGGATTTTGAATTGGAAGAAGGGATGAAAGTACTTGCGATTGGA
CGTATTAGCATTTATCCCCCTTCTGGGTCATATTCTATAAATATTGAGAGTTTAGTTCCTGATGGAGTTGGAGCGCTTGC
CCTTAAGTTTGAACAATTGAAGAAAAAATTAGCGGCAGAAGGACTTTTTGACCAACGTTGGAAACAAAATCTACCACAAT
TTTCCAAAAAAATTGCGGTGGTCACGAGTCCATCAGGAGCAGTTATCAGAGATATTATTACAACCGTTCAACGCCGTTTT
CCAATGAGTCAAATTGTCTTATATCCGACTAAAGTTCAAGGAGCTGGCGCGGCCGAAGAAATTTCTGGAAATATCCGACG
CGCCAATGAACGTGGCGATTTTGATGTGATGATTATTGGTCGGGGTGGCGGCTCTATCGAGGATTTATGGGGATTTAATG
AAGAGATTGTTGTTCGAGCAATTTTTGAATCACGTATTCCAATTATTTCATCAGTTGGACACGAAACTGATGTGACCTTG
GCCGATTTTGTAGCTGATAGTCGTGCTGCTACACCAACTGCCGCCGCTGAATTAGCCACACCAAATACAAAAATTGACTT
AATCAATTGGGCAAATGAGCAAGAAAGTCGTCTTTTTAATCGTTTAACTCATTTGATTAAAATTCGTAGAGAGCGACTTG
AAAAATTAAGTCAGTCAGTGGTGTTTAGACAACCTGAACGCCTTTACGATGGACATGTACAAAAACTTGACCGATTGTGC
GAACGATTGACAGTACTGACAGAAAATAAAGTTGCAAATATGAAGCACCGTTATGAGCTGTCAGCAAATAGATTGATTCC
AACCTATAGTAAAATTGTTGAAAGTAAAAAAAATAAGACCGAGCAACTCTATCAGTCTTTGCTTTTATTAGATATTTCAA
AAATAAAAGCGCGTGGTTTTTCCCTAATTACTGACGAAAATGGAAAAATCATTAAATCCGTAAGCGATGTAAAAAAAGGT
CAGGCACTTGATGTGGAATTAACTGACGGACAAGTAAAAGTGGAGGTAAAATAA

Upstream 100 bases:

>100_bases
TCAGGACATAAACTTTTTACTTTTTTTCGATTTTACAAAGTAGAGTAAAAATTGACAAGTTGTCAGTAAAATTAATTAGA
GAAATATGAAGAGTGAGGGA

Downstream 100 bases:

>100_bases
AAATGGCAACAAAAAAAGAAGAAGTAAAATTTGAAGATAATTTAGCAGAATTAGAAAATATCGTACGTAAGTTAGAATCT
GGTGATGTTGCGTTGGAAGA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTEYLSVSTLTKYLKAKFERDPYLERVYLTGEISNFRRRPNHQYFALKDEGAVIQATMWAGQFRKLDFELEEGMKVLAIG
RISIYPPSGSYSINIESLVPDGVGALALKFEQLKKKLAAEGLFDQRWKQNLPQFSKKIAVVTSPSGAVIRDIITTVQRRF
PMSQIVLYPTKVQGAGAAEEISGNIRRANERGDFDVMIIGRGGGSIEDLWGFNEEIVVRAIFESRIPIISSVGHETDVTL
ADFVADSRAATPTAAAELATPNTKIDLINWANEQESRLFNRLTHLIKIRRERLEKLSQSVVFRQPERLYDGHVQKLDRLC
ERLTVLTENKVANMKHRYELSANRLIPTYSKIVESKKNKTEQLYQSLLLLDISKIKARGFSLITDENGKIIKSVSDVKKG
QALDVELTDGQVKVEVK

Sequences:

>Translated_417_residues
MTEYLSVSTLTKYLKAKFERDPYLERVYLTGEISNFRRRPNHQYFALKDEGAVIQATMWAGQFRKLDFELEEGMKVLAIG
RISIYPPSGSYSINIESLVPDGVGALALKFEQLKKKLAAEGLFDQRWKQNLPQFSKKIAVVTSPSGAVIRDIITTVQRRF
PMSQIVLYPTKVQGAGAAEEISGNIRRANERGDFDVMIIGRGGGSIEDLWGFNEEIVVRAIFESRIPIISSVGHETDVTL
ADFVADSRAATPTAAAELATPNTKIDLINWANEQESRLFNRLTHLIKIRRERLEKLSQSVVFRQPERLYDGHVQKLDRLC
ERLTVLTENKVANMKHRYELSANRLIPTYSKIVESKKNKTEQLYQSLLLLDISKIKARGFSLITDENGKIIKSVSDVKKG
QALDVELTDGQVKVEVK
>Mature_416_residues
TEYLSVSTLTKYLKAKFERDPYLERVYLTGEISNFRRRPNHQYFALKDEGAVIQATMWAGQFRKLDFELEEGMKVLAIGR
ISIYPPSGSYSINIESLVPDGVGALALKFEQLKKKLAAEGLFDQRWKQNLPQFSKKIAVVTSPSGAVIRDIITTVQRRFP
MSQIVLYPTKVQGAGAAEEISGNIRRANERGDFDVMIIGRGGGSIEDLWGFNEEIVVRAIFESRIPIISSVGHETDVTLA
DFVADSRAATPTAAAELATPNTKIDLINWANEQESRLFNRLTHLIKIRRERLEKLSQSVVFRQPERLYDGHVQKLDRLCE
RLTVLTENKVANMKHRYELSANRLIPTYSKIVESKKNKTEQLYQSLLLLDISKIKARGFSLITDENGKIIKSVSDVKKGQ
ALDVELTDGQVKVEVK

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=437, Percent_Identity=36.3844393592677, Blast_Score=278, Evalue=5e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 47150; Mature: 47019

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEYLSVSTLTKYLKAKFERDPYLERVYLTGEISNFRRRPNHQYFALKDEGAVIQATMWA
CCCEEHHHHHHHHHHHHCCCCCCEEEEEEEEEHHHHHCCCCCCEEEEECCCCEEEEEECC
GQFRKLDFELEEGMKVLAIGRISIYPPSGSYSINIESLVPDGVGALALKFEQLKKKLAAE
CCHHEECEEHHCCCEEEEEEEEEEECCCCCEEEEEHEECCCCCHHHHHHHHHHHHHHHHC
GLFDQRWKQNLPQFSKKIAVVTSPSGAVIRDIITTVQRRFPMSQIVLYPTKVQGAGAAEE
CHHHHHHHHCCHHHHHCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHH
ISGNIRRANERGDFDVMIIGRGGGSIEDLWGFNEEIVVRAIFESRIPIISSVGHETDVTL
HCCCCEECCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCCHH
ADFVADSRAATPTAAAELATPNTKIDLINWANEQESRLFNRLTHLIKIRRERLEKLSQSV
HHHHHCCCCCCCCHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFRQPERLYDGHVQKLDRLCERLTVLTENKVANMKHRYELSANRLIPTYSKIVESKKNKT
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHEECCCCCCCHHHHHHHHHHCCHH
EQLYQSLLLLDISKIKARGFSLITDENGKIIKSVSDVKKGQALDVELTDGQVKVEVK
HHHHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHCCCCEEEEEEECCEEEEEEC
>Mature Secondary Structure 
TEYLSVSTLTKYLKAKFERDPYLERVYLTGEISNFRRRPNHQYFALKDEGAVIQATMWA
CCEEHHHHHHHHHHHHCCCCCCEEEEEEEEEHHHHHCCCCCCEEEEECCCCEEEEEECC
GQFRKLDFELEEGMKVLAIGRISIYPPSGSYSINIESLVPDGVGALALKFEQLKKKLAAE
CCHHEECEEHHCCCEEEEEEEEEEECCCCCEEEEEHEECCCCCHHHHHHHHHHHHHHHHC
GLFDQRWKQNLPQFSKKIAVVTSPSGAVIRDIITTVQRRFPMSQIVLYPTKVQGAGAAEE
CHHHHHHHHCCHHHHHCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHH
ISGNIRRANERGDFDVMIIGRGGGSIEDLWGFNEEIVVRAIFESRIPIISSVGHETDVTL
HCCCCEECCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCCHH
ADFVADSRAATPTAAAELATPNTKIDLINWANEQESRLFNRLTHLIKIRRERLEKLSQSV
HHHHHCCCCCCCCHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFRQPERLYDGHVQKLDRLCERLTVLTENKVANMKHRYELSANRLIPTYSKIVESKKNKT
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHEECCCCCCCHHHHHHHHHHCCHH
EQLYQSLLLLDISKIKARGFSLITDENGKIIKSVSDVKKGQALDVELTDGQVKVEVK
HHHHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHCCCCEEEEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]