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The map label for this gene is mraY [H]

Identifier: 125624476

GI number: 125624476

Start: 1652246

End: 1653235

Strand: Reverse

Name: mraY [H]

Synonym: llmg_1678

Alternate gene names: 125624476

Gene position: 1653235-1652246 (Counterclockwise)

Preceding gene: 125624477

Following gene: 125624475

Centisome position: 65.36

GC content: 37.07

Gene sequence:

>990_bases
ATGTTATTGAATGGAATAGTGGCGGCGGTAATTACAATGATTATAACAATCATTGGTATTCCTCGCTTCATTATGTTCTT
CCACAAGAAAAAATTGGGTGGACAGCCAACACTTGAAGATGTGAAGCAACATGCTAGTAAAGCCGGAACTCCCACGATGG
GTGGATTTGTCTTTGTGGTTGTCAGCTTAGTTGTTTCATTGGTTGCGGCTTTGGTTTTTGGAAAATTTAGTCCAGCTTTT
ATTACCGCTTGGTGGGTTTTTGCCATGTATGCTGTCATTGGTTTCTTGGATGACTTCTTGAAAGTCTTCAAACAAATTAA
TGAAGGTTTGACAGCTAAACAAAAAATGCTCGCTCAAATTTTAATTGGGATTGTTTCATATTTTATTTACAGTCATGGTG
AAAAATCACATATCATTCATATTTTGAGTTGGCAAGTTAATATTGGGATTTTCTTCTCTATTTTCATTATTATTTGGCTA
GTAGGCTGGTCAAATGCGGTCAATCTTACTGATGGAATTGATGGATTGGCTTCAATTACTGTCGCGATTTCACTGACAGC
TTATGCAGTTATTGCTGTTGTTCATCAACAGTATGATGTTTTACTGATTATTCTGTCAGTAATTGGTGGTCTACTTGGAT
TCTTCGTTTTCAATCACAAACCGGCAAAAATTTTCATGGGTGATGTGGGTTCGTTAGCCTTAGGTGGATTTCTTGCTATT
GTTTCAATCTTGCTTCATGCAGAATGGACCTTACTTTTAATTGGTGCTGTCTATGTGATTGAAACACTTTCAGTGATGTT
ACAAGTGGCCTACTTCAAGAAAACTGGTGGTAAACGTATTTTTAGAATGACACCTATTCATCATCATTTTGAACTTGGAG
GTTTTTCTGGGAAAGCTGCTGGTTGGTCAGAATGGAAAATTGACATTGTTTTCTGGCTCTTTACAGCTGTTCTGTCAGTA
ATCGCGCTTTGTATTTACTTCGCTTTTTAA

Upstream 100 bases:

>100_bases
CGCTCACTGTAAAAATGGGTAATTAAGTAGAATTTAAATTTATCAATTTGGGGCTCCACAAAGTTGGTCTTTGTGGAGCT
TCAAAAATTAGGAGAAGAAA

Downstream 100 bases:

>100_bases
TTAATAAATTTACTGACAGAATGGTCAGTGAAAAGTCGCTCTTGTGAGCGGCTTTTTTTATTTAAAAAATCTAATAGTTT
GCTGACAGAATACTCAAGAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MLLNGIVAAVITMIITIIGIPRFIMFFHKKKLGGQPTLEDVKQHASKAGTPTMGGFVFVVVSLVVSLVAALVFGKFSPAF
ITAWWVFAMYAVIGFLDDFLKVFKQINEGLTAKQKMLAQILIGIVSYFIYSHGEKSHIIHILSWQVNIGIFFSIFIIIWL
VGWSNAVNLTDGIDGLASITVAISLTAYAVIAVVHQQYDVLLIILSVIGGLLGFFVFNHKPAKIFMGDVGSLALGGFLAI
VSILLHAEWTLLLIGAVYVIETLSVMLQVAYFKKTGGKRIFRMTPIHHHFELGGFSGKAAGWSEWKIDIVFWLFTAVLSV
IALCIYFAF

Sequences:

>Translated_329_residues
MLLNGIVAAVITMIITIIGIPRFIMFFHKKKLGGQPTLEDVKQHASKAGTPTMGGFVFVVVSLVVSLVAALVFGKFSPAF
ITAWWVFAMYAVIGFLDDFLKVFKQINEGLTAKQKMLAQILIGIVSYFIYSHGEKSHIIHILSWQVNIGIFFSIFIIIWL
VGWSNAVNLTDGIDGLASITVAISLTAYAVIAVVHQQYDVLLIILSVIGGLLGFFVFNHKPAKIFMGDVGSLALGGFLAI
VSILLHAEWTLLLIGAVYVIETLSVMLQVAYFKKTGGKRIFRMTPIHHHFELGGFSGKAAGWSEWKIDIVFWLFTAVLSV
IALCIYFAF
>Mature_329_residues
MLLNGIVAAVITMIITIIGIPRFIMFFHKKKLGGQPTLEDVKQHASKAGTPTMGGFVFVVVSLVVSLVAALVFGKFSPAF
ITAWWVFAMYAVIGFLDDFLKVFKQINEGLTAKQKMLAQILIGIVSYFIYSHGEKSHIIHILSWQVNIGIFFSIFIIIWL
VGWSNAVNLTDGIDGLASITVAISLTAYAVIAVVHQQYDVLLIILSVIGGLLGFFVFNHKPAKIFMGDVGSLALGGFLAI
VSILLHAEWTLLLIGAVYVIETLSVMLQVAYFKKTGGKRIFRMTPIHHHFELGGFSGKAAGWSEWKIDIVFWLFTAVLSV
IALCIYFAF

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=342, Percent_Identity=35.0877192982456, Blast_Score=175, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 36222; Mature: 36222

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLNGIVAAVITMIITIIGIPRFIMFFHKKKLGGQPTLEDVKQHASKAGTPTMGGFVFVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHH
VSLVVSLVAALVFGKFSPAFITAWWVFAMYAVIGFLDDFLKVFKQINEGLTAKQKMLAQI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LIGIVSYFIYSHGEKSHIIHILSWQVNIGIFFSIFIIIWLVGWSNAVNLTDGIDGLASIT
HHHHHHHHHHCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VAISLTAYAVIAVVHQQYDVLLIILSVIGGLLGFFVFNHKPAKIFMGDVGSLALGGFLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHH
VSILLHAEWTLLLIGAVYVIETLSVMLQVAYFKKTGGKRIFRMTPIHHHFELGGFSGKAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHEECCCCCCCC
GWSEWKIDIVFWLFTAVLSVIALCIYFAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLNGIVAAVITMIITIIGIPRFIMFFHKKKLGGQPTLEDVKQHASKAGTPTMGGFVFVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHH
VSLVVSLVAALVFGKFSPAFITAWWVFAMYAVIGFLDDFLKVFKQINEGLTAKQKMLAQI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LIGIVSYFIYSHGEKSHIIHILSWQVNIGIFFSIFIIIWLVGWSNAVNLTDGIDGLASIT
HHHHHHHHHHCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VAISLTAYAVIAVVHQQYDVLLIILSVIGGLLGFFVFNHKPAKIFMGDVGSLALGGFLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHH
VSILLHAEWTLLLIGAVYVIETLSVMLQVAYFKKTGGKRIFRMTPIHHHFELGGFSGKAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHEECCCCCCCC
GWSEWKIDIVFWLFTAVLSVIALCIYFAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]