| Definition | Lactococcus lactis subsp. cremoris MG1363, complete genome. |
|---|---|
| Accession | NC_009004 |
| Length | 2,529,478 |
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The map label for this gene is ppiB [C]
Identifier: 125624445
GI number: 125624445
Start: 1623991
End: 1624581
Strand: Reverse
Name: ppiB [C]
Synonym: llmg_1646
Alternate gene names: 125624445
Gene position: 1624581-1623991 (Counterclockwise)
Preceding gene: 125624446
Following gene: 125624444
Centisome position: 64.23
GC content: 38.07
Gene sequence:
>591_bases ATGACTTACCCACAACTTGATCTTGAAAACTACAAAGGCACCACAGCAATTATTAATACCAATCATGGAAAAATGACTGT CAAATTATTTGATAGTCTTGCTCCTAAAACAGTAAAAAACTTTATTGAACTCAGTAAAGAAGGCTATTATGATGGTGTGA TTTTCCACCGAATCATCAAAGATTTTATGATTCAAGGAGGAGATCCAACAGGAACTGGGATGGGTGGTTCTTCAATTTAT GGTGAAAAATTTGAGGATGAGTTCTCAATGGATCTCTTTAATCTTCGTGGAGCTTTGTCAATGGCAAATGCTGGGCCTAA TACGAACGGTAGTCAATTTTTCATCGTTCAAAATAAAAACTTGCCTTATCCAAAGGACTCTCTTATTCAAGGGGGTTGGC CTGAAGAAGTAGCAGAAACATATACTGATGGTGGAACTCCGCATCTTGACGGTCGTCATACTGTTTTTGGTCAATTAGTT GACGAAGAAAGCTACAAAGTCCTTGATAAAATCGTAGCTGTACGTGTGGGTGCACAAGATAAACCAGTTGACGATGTTGT CATTGAATCAGTTGAGATTATCGAGCCATAA
Upstream 100 bases:
>100_bases GACAAATCTGTCAGTAAAAAATAAAACTGACAGATTCGTCAGTAACTTAAACTATGAAGAAAGGAAGGCATTTTTTAAAT AGAATGCCGACTAAAAAATT
Downstream 100 bases:
>100_bases AATGGATAAAAAAAGTCCTAAAATCGGAGATATTGTTGAAGTTGAAATCATTGGAATGCAGGATTATGGTGCATTTGTAA AGTTTTTCCTGCAAAATCCA
Product: peptidyl-prolyl cis-trans isomerase
Products: NA
Alternate protein names: Phosphatase; Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]
Number of amino acids: Translated: 196; Mature: 195
Protein sequence:
>196_residues MTYPQLDLENYKGTTAIINTNHGKMTVKLFDSLAPKTVKNFIELSKEGYYDGVIFHRIIKDFMIQGGDPTGTGMGGSSIY GEKFEDEFSMDLFNLRGALSMANAGPNTNGSQFFIVQNKNLPYPKDSLIQGGWPEEVAETYTDGGTPHLDGRHTVFGQLV DEESYKVLDKIVAVRVGAQDKPVDDVVIESVEIIEP
Sequences:
>Translated_196_residues MTYPQLDLENYKGTTAIINTNHGKMTVKLFDSLAPKTVKNFIELSKEGYYDGVIFHRIIKDFMIQGGDPTGTGMGGSSIY GEKFEDEFSMDLFNLRGALSMANAGPNTNGSQFFIVQNKNLPYPKDSLIQGGWPEEVAETYTDGGTPHLDGRHTVFGQLV DEESYKVLDKIVAVRVGAQDKPVDDVVIESVEIIEP >Mature_195_residues TYPQLDLENYKGTTAIINTNHGKMTVKLFDSLAPKTVKNFIELSKEGYYDGVIFHRIIKDFMIQGGDPTGTGMGGSSIYG EKFEDEFSMDLFNLRGALSMANAGPNTNGSQFFIVQNKNLPYPKDSLIQGGWPEEVAETYTDGGTPHLDGRHTVFGQLVD EESYKVLDKIVAVRVGAQDKPVDDVVIESVEIIEP
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI7706339, Length=181, Percent_Identity=44.7513812154696, Blast_Score=150, Evalue=5e-37, Organism=Homo sapiens, GI24308049, Length=181, Percent_Identity=46.9613259668508, Blast_Score=140, Evalue=1e-33, Organism=Homo sapiens, GI19557636, Length=181, Percent_Identity=42.5414364640884, Blast_Score=138, Evalue=2e-33, Organism=Homo sapiens, GI64276486, Length=179, Percent_Identity=37.9888268156425, Blast_Score=129, Evalue=1e-30, Organism=Homo sapiens, GI4758950, Length=178, Percent_Identity=41.5730337078652, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI4505991, Length=171, Percent_Identity=42.1052631578947, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI4826932, Length=150, Percent_Identity=44, Blast_Score=107, Evalue=5e-24, Organism=Homo sapiens, GI22547215, Length=179, Percent_Identity=40.2234636871508, Blast_Score=104, Evalue=5e-23, Organism=Homo sapiens, GI22547212, Length=179, Percent_Identity=40.2234636871508, Blast_Score=104, Evalue=5e-23, Organism=Homo sapiens, GI7657473, Length=179, Percent_Identity=40.2234636871508, Blast_Score=104, Evalue=5e-23, Organism=Homo sapiens, GI42560244, Length=187, Percent_Identity=38.5026737967914, Blast_Score=103, Evalue=9e-23, Organism=Homo sapiens, GI5454154, Length=178, Percent_Identity=39.8876404494382, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI10863927, Length=141, Percent_Identity=46.0992907801418, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI6631100, Length=178, Percent_Identity=36.5168539325843, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI256017253, Length=144, Percent_Identity=43.75, Blast_Score=99, Evalue=2e-21, Organism=Homo sapiens, GI221139811, Length=144, Percent_Identity=43.75, Blast_Score=99, Evalue=2e-21, Organism=Homo sapiens, GI256017251, Length=144, Percent_Identity=43.75, Blast_Score=99, Evalue=2e-21, Organism=Homo sapiens, GI178057341, Length=141, Percent_Identity=43.9716312056738, Blast_Score=96, Evalue=1e-20, Organism=Homo sapiens, GI209417936, Length=141, Percent_Identity=43.9716312056738, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI30102944, Length=141, Percent_Identity=43.9716312056738, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI219842199, Length=141, Percent_Identity=43.9716312056738, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI5174637, Length=177, Percent_Identity=39.5480225988701, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI310129267, Length=167, Percent_Identity=40.1197604790419, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI310120620, Length=167, Percent_Identity=40.1197604790419, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI5031987, Length=157, Percent_Identity=40.7643312101911, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI20911035, Length=184, Percent_Identity=31.5217391304348, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI310110104, Length=167, Percent_Identity=39.5209580838323, Blast_Score=89, Evalue=2e-18, Organism=Homo sapiens, GI303305009, Length=159, Percent_Identity=39.622641509434, Blast_Score=89, Evalue=2e-18, Organism=Homo sapiens, GI45439316, Length=159, Percent_Identity=39.622641509434, Blast_Score=89, Evalue=2e-18, Organism=Homo sapiens, GI169163387, Length=103, Percent_Identity=52.4271844660194, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI150418007, Length=147, Percent_Identity=39.4557823129252, Blast_Score=87, Evalue=6e-18, Organism=Homo sapiens, GI169164185, Length=99, Percent_Identity=53.5353535353535, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI169163623, Length=99, Percent_Identity=53.5353535353535, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI310127646, Length=141, Percent_Identity=41.1347517730496, Blast_Score=85, Evalue=4e-17, Organism=Homo sapiens, GI310114371, Length=141, Percent_Identity=41.1347517730496, Blast_Score=85, Evalue=4e-17, Organism=Homo sapiens, GI310119221, Length=141, Percent_Identity=41.1347517730496, Blast_Score=85, Evalue=4e-17, Organism=Homo sapiens, GI27735045, Length=150, Percent_Identity=37.3333333333333, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI310132444, Length=95, Percent_Identity=53.6842105263158, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI310113152, Length=95, Percent_Identity=53.6842105263158, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI14277126, Length=124, Percent_Identity=41.1290322580645, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI169214050, Length=153, Percent_Identity=37.9084967320261, Blast_Score=78, Evalue=5e-15, Organism=Homo sapiens, GI239751853, Length=153, Percent_Identity=37.9084967320261, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI113428306, Length=153, Percent_Identity=37.9084967320261, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI310127745, Length=129, Percent_Identity=41.8604651162791, Blast_Score=74, Evalue=6e-14, Organism=Homo sapiens, GI310119290, Length=129, Percent_Identity=41.8604651162791, Blast_Score=74, Evalue=6e-14, Organism=Homo sapiens, GI310114540, Length=129, Percent_Identity=41.8604651162791, Blast_Score=74, Evalue=7e-14, Organism=Homo sapiens, GI289803023, Length=176, Percent_Identity=31.8181818181818, Blast_Score=70, Evalue=9e-13, Organism=Escherichia coli, GI1786736, Length=186, Percent_Identity=38.7096774193548, Blast_Score=99, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17539496, Length=173, Percent_Identity=45.6647398843931, Blast_Score=140, Evalue=3e-34, Organism=Caenorhabditis elegans, GI71997782, Length=167, Percent_Identity=40.7185628742515, Blast_Score=124, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17552780, Length=172, Percent_Identity=46.5116279069767, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17506311, Length=181, Percent_Identity=40.3314917127072, Blast_Score=120, Evalue=5e-28, Organism=Caenorhabditis elegans, GI71980594, Length=180, Percent_Identity=37.2222222222222, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI71980590, Length=170, Percent_Identity=37.6470588235294, Blast_Score=117, Evalue=4e-27, Organism=Caenorhabditis elegans, GI17532641, Length=177, Percent_Identity=40.1129943502825, Blast_Score=116, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17506307, Length=174, Percent_Identity=45.4022988505747, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17551282, Length=176, Percent_Identity=41.4772727272727, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17551284, Length=176, Percent_Identity=41.4772727272727, Blast_Score=107, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17559074, Length=179, Percent_Identity=42.4581005586592, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17565860, Length=175, Percent_Identity=43.4285714285714, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17566266, Length=150, Percent_Identity=42, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17539498, Length=143, Percent_Identity=42.6573426573427, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17552784, Length=185, Percent_Identity=36.7567567567568, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17552782, Length=150, Percent_Identity=38.6666666666667, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17532643, Length=176, Percent_Identity=37.5, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI32563659, Length=185, Percent_Identity=32.972972972973, Blast_Score=88, Evalue=3e-18, Organism=Saccharomyces cerevisiae, GI6323562, Length=180, Percent_Identity=42.7777777777778, Blast_Score=110, Evalue=1e-25, Organism=Saccharomyces cerevisiae, GI6321848, Length=175, Percent_Identity=40, Blast_Score=108, Evalue=7e-25, Organism=Saccharomyces cerevisiae, GI6320359, Length=175, Percent_Identity=41.1428571428571, Blast_Score=106, Evalue=2e-24, Organism=Saccharomyces cerevisiae, GI6323246, Length=188, Percent_Identity=37.2340425531915, Blast_Score=103, Evalue=3e-23, Organism=Saccharomyces cerevisiae, GI6320510, Length=172, Percent_Identity=38.953488372093, Blast_Score=97, Evalue=2e-21, Organism=Saccharomyces cerevisiae, GI6322492, Length=209, Percent_Identity=33.4928229665072, Blast_Score=83, Evalue=3e-17, Organism=Drosophila melanogaster, GI19922376, Length=178, Percent_Identity=43.8202247191011, Blast_Score=152, Evalue=2e-37, Organism=Drosophila melanogaster, GI17986117, Length=177, Percent_Identity=44.6327683615819, Blast_Score=142, Evalue=2e-34, Organism=Drosophila melanogaster, GI20130249, Length=172, Percent_Identity=45.9302325581395, Blast_Score=117, Evalue=7e-27, Organism=Drosophila melanogaster, GI21357249, Length=179, Percent_Identity=35.195530726257, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI24652460, Length=181, Percent_Identity=35.3591160220994, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI19922912, Length=179, Percent_Identity=43.5754189944134, Blast_Score=107, Evalue=5e-24, Organism=Drosophila melanogaster, GI24650807, Length=178, Percent_Identity=37.0786516853933, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI17647301, Length=178, Percent_Identity=38.7640449438202, Blast_Score=95, Evalue=3e-20, Organism=Drosophila melanogaster, GI24664125, Length=174, Percent_Identity=39.6551724137931, Blast_Score=94, Evalue=6e-20, Organism=Drosophila melanogaster, GI21357783, Length=174, Percent_Identity=39.6551724137931, Blast_Score=94, Evalue=6e-20, Organism=Drosophila melanogaster, GI24586038, Length=185, Percent_Identity=36.2162162162162, Blast_Score=94, Evalue=6e-20, Organism=Drosophila melanogaster, GI45549139, Length=157, Percent_Identity=42.0382165605096, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI17136360, Length=177, Percent_Identity=36.7231638418079, Blast_Score=91, Evalue=5e-19, Organism=Drosophila melanogaster, GI21355677, Length=189, Percent_Identity=32.8042328042328, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI24661775, Length=105, Percent_Identity=40.9523809523809, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI21355237, Length=105, Percent_Identity=40.9523809523809, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24661771, Length=105, Percent_Identity=40.9523809523809, Blast_Score=69, Evalue=2e-12,
Paralogues:
None
Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR023214 - InterPro: IPR013200 - InterPro: IPR006379 - InterPro: IPR000150 - InterPro: IPR002130 [H]
Pfam domain/function: PF08282 Hydrolase_3; PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 21646; Mature: 21514
Theoretical pI: Translated: 4.43; Mature: 4.43
Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTYPQLDLENYKGTTAIINTNHGKMTVKLFDSLAPKTVKNFIELSKEGYYDGVIFHRIIK CCCCCCCCCCCCCCEEEEECCCCEEEEEEHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHH DFMIQGGDPTGTGMGGSSIYGEKFEDEFSMDLFNLRGALSMANAGPNTNGSQFFIVQNKN HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC LPYPKDSLIQGGWPEEVAETYTDGGTPHLDGRHTVFGQLVDEESYKVLDKIVAVRVGAQD CCCCHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCC KPVDDVVIESVEIIEP CCHHHHHHHHHHHCCC >Mature Secondary Structure TYPQLDLENYKGTTAIINTNHGKMTVKLFDSLAPKTVKNFIELSKEGYYDGVIFHRIIK CCCCCCCCCCCCCEEEEECCCCEEEEEEHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHH DFMIQGGDPTGTGMGGSSIYGEKFEDEFSMDLFNLRGALSMANAGPNTNGSQFFIVQNKN HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC LPYPKDSLIQGGWPEEVAETYTDGGTPHLDGRHTVFGQLVDEESYKVLDKIVAVRVGAQD CCCCHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCC KPVDDVVIESVEIIEP CCHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA