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The map label for this gene is xpt [H]

Identifier: 125624165

GI number: 125624165

Start: 1320261

End: 1320854

Strand: Reverse

Name: xpt [H]

Synonym: llmg_1346

Alternate gene names: 125624165

Gene position: 1320854-1320261 (Counterclockwise)

Preceding gene: 125624166

Following gene: 125624164

Centisome position: 52.22

GC content: 37.21

Gene sequence:

>594_bases
ATGAAGTTATTAGAAGACCGCATTAATACAGACGGTCAAGTATTAGGCCAAGACATTCTTAAAGTTGACCGCTTTTTGAC
ACACCAAGTGGATTATCAATTGATGAAGGAAATCGGTAAGCGTTTTGCACAAGTTTATGCAGATGCCGGAGTTACAAAGG
TTGTAACGATTGAAGCAAGTGGAATTGCCCCTGCTTTATATGCTGCTGAATCACTCAATGTTCCAATGATTTTTGCTAAA
AAAGCTAAAAATGTGACTATGAATGATGATTTATTGATTACAGAAGTTTATTCTTTCACTAAAAAATTAACTTCTACCGT
TCAAATTTCAAGTAAACTGATTGAAGAAGGCGATAAAGTCTTGATTATTGATGACTTTTTGGCCAATGGACAAGCAGCAC
TTGGTTTGGTTCATTTGATGGAACAAGCCAAAGCAGAAGTTGTTGGTCTAGGAATGGTGATTGAAAAATCTTTCCAAGAT
GGACGTCAAAAACTTCTTGATCAAGGAATGAAACTTACCAGTCTTGCCCGGATTGAGAAGTTTGAAGATGGTAAAGTAAT
CTTCGCCCCAGCGGACGATATCGCTTTCGATTAA

Upstream 100 bases:

>100_bases
TTTCTTTTTTGCGTATTTGAAACGTCTTGTTATTTTTTATAACGAGACGTTTTTCTCACCTGGGGCACAGATGAGAAAAA
AATTTTTTAAGGAGAGAATA

Downstream 100 bases:

>100_bases
AACTAAGCAATAAGCAATTAAAAAGAATAAAAAAAGAAAAATTTAAGGAAAATCAAAATGCCTCATAAAAATGAACAAAG
CCAGGAGCAAAGTAACTCTA

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKLLEDRINTDGQVLGQDILKVDRFLTHQVDYQLMKEIGKRFAQVYADAGVTKVVTIEASGIAPALYAAESLNVPMIFAK
KAKNVTMNDDLLITEVYSFTKKLTSTVQISSKLIEEGDKVLIIDDFLANGQAALGLVHLMEQAKAEVVGLGMVIEKSFQD
GRQKLLDQGMKLTSLARIEKFEDGKVIFAPADDIAFD

Sequences:

>Translated_197_residues
MKLLEDRINTDGQVLGQDILKVDRFLTHQVDYQLMKEIGKRFAQVYADAGVTKVVTIEASGIAPALYAAESLNVPMIFAK
KAKNVTMNDDLLITEVYSFTKKLTSTVQISSKLIEEGDKVLIIDDFLANGQAALGLVHLMEQAKAEVVGLGMVIEKSFQD
GRQKLLDQGMKLTSLARIEKFEDGKVIFAPADDIAFD
>Mature_197_residues
MKLLEDRINTDGQVLGQDILKVDRFLTHQVDYQLMKEIGKRFAQVYADAGVTKVVTIEASGIAPALYAAESLNVPMIFAK
KAKNVTMNDDLLITEVYSFTKKLTSTVQISSKLIEEGDKVLIIDDFLANGQAALGLVHLMEQAKAEVVGLGMVIEKSFQD
GRQKLLDQGMKLTSLARIEKFEDGKVIFAPADDIAFD

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR010079 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 21726; Mature: 21726

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLEDRINTDGQVLGQDILKVDRFLTHQVDYQLMKEIGKRFAQVYADAGVTKVVTIEAS
CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GIAPALYAAESLNVPMIFAKKAKNVTMNDDLLITEVYSFTKKLTSTVQISSKLIEEGDKV
CCCHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LIIDDFLANGQAALGLVHLMEQAKAEVVGLGMVIEKSFQDGRQKLLDQGMKLTSLARIEK
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FEDGKVIFAPADDIAFD
CCCCCEEEECCCCCCCC
>Mature Secondary Structure
MKLLEDRINTDGQVLGQDILKVDRFLTHQVDYQLMKEIGKRFAQVYADAGVTKVVTIEAS
CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GIAPALYAAESLNVPMIFAKKAKNVTMNDDLLITEVYSFTKKLTSTVQISSKLIEEGDKV
CCCHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LIIDDFLANGQAALGLVHLMEQAKAEVVGLGMVIEKSFQDGRQKLLDQGMKLTSLARIEK
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FEDGKVIFAPADDIAFD
CCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]