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The map label for this gene is arsB [H]

Identifier: 125624075

GI number: 125624075

Start: 1222048

End: 1223100

Strand: Direct

Name: arsB [H]

Synonym: llmg_1250

Alternate gene names: 125624075

Gene position: 1222048-1223100 (Clockwise)

Preceding gene: 125624074

Following gene: 125624076

Centisome position: 48.31

GC content: 35.04

Gene sequence:

>1053_bases
ATGAATCAAGTCACAAAGAAACTGTCGTTTTTCGACCGTTATCTGACACTTTGGATATTTGTAGCAATGGGAATTGGAGT
CGCTTTGGGATACTTCGTTCCTAGTGTTGCAACCACTATTAATGACTTATCAGTAGGAACAACATCAATTCCAATTGCCA
TTGGACTAATTCTCATGATGTATCCTCCATTAGTAAAAGTAAAATATGGAGAAATGGGAAAAGTATTTAAGGATTGGAAA
GTCTTGTTGCTTTCATTAGTTCAAAACTGGATTATTGGTCCGATACTAATGTTTATTCTTGCGGTCGTATTTTTACAAGG
TTATCCAAGCTATATGATTGGGCTTATCATGATTGGGCTTGCACGTTGTATTGCAATGGTTATTGTTTGGACTGATTTAG
CACATGGTGATAGTGAGTATACAGCAGGACTTGTAGCCTTCAACTCACTTTTCCAAGTATTCTTTTACTCAATCTTTGCT
TATTTCTTTGTAACCTTGCTTCCAAAATGGTTAGGTTTAGGAAATTTTGCAGTGCATATAACAATTGGTGAGATTGCTAC
CTCAGTATTCATCTATTTGGGAATTCCATTTATTGCAGGGATTATCTCTCATTTTGGTTTGATTAAATTAAAAGGTAAAG
AATGGTTTGAAGAAAAATTCATTCCAAAAATTAGTCGTATAACATTGGTTGCTCTTTTGTTTACAATCATTATCATGTTT
GCGGTTAAGGGTGAAAAGGTAGTAGAGCTTCCATTTGACGTAGTTAGAATAGCAATTCCATTGCTTCTGTACTTCGTATT
GATGTTCTTTGTTTCCTTCTTTCTCTCTAAAAAACTGGGAACAAGTTATCCTGTTACAGCATCTTTATCATTTACAGCAG
GAAGCAATAACTTTGAGCTTGCGATAGCAGTTGCGGTAGGTGTATTTGGAATTAATTCAGGAGAAGCCTTTGCGGCAGTT
ATTGGTCCGTTAGTGGAAGTTCCTGTTATGATTGCTTTAGTTAATGTGGCTTTGAAATTTAAAAAAATCTATTTTACAAA
AGAATCCGTATAA

Upstream 100 bases:

>100_bases
GAGGAATGAAGGATTTAGAGAAGTATACAATTTATCAGGCGGAAATAAAAATTATCAAGAAATTGCAAAACAAGAAAAAA
ATTAGGGGAAAAACTCAATT

Downstream 100 bases:

>100_bases
GGTGTATTATGAAATTTAAATTCACATCTCTTTCTTCGGCTGAAGAGAATTCTATCAATAATTACACGGGTGAAAAAAGT
GGAGACTATATTATTAAAGA

Product: putative arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MNQVTKKLSFFDRYLTLWIFVAMGIGVALGYFVPSVATTINDLSVGTTSIPIAIGLILMMYPPLVKVKYGEMGKVFKDWK
VLLLSLVQNWIIGPILMFILAVVFLQGYPSYMIGLIMIGLARCIAMVIVWTDLAHGDSEYTAGLVAFNSLFQVFFYSIFA
YFFVTLLPKWLGLGNFAVHITIGEIATSVFIYLGIPFIAGIISHFGLIKLKGKEWFEEKFIPKISRITLVALLFTIIIMF
AVKGEKVVELPFDVVRIAIPLLLYFVLMFFVSFFLSKKLGTSYPVTASLSFTAGSNNFELAIAVAVGVFGINSGEAFAAV
IGPLVEVPVMIALVNVALKFKKIYFTKESV

Sequences:

>Translated_350_residues
MNQVTKKLSFFDRYLTLWIFVAMGIGVALGYFVPSVATTINDLSVGTTSIPIAIGLILMMYPPLVKVKYGEMGKVFKDWK
VLLLSLVQNWIIGPILMFILAVVFLQGYPSYMIGLIMIGLARCIAMVIVWTDLAHGDSEYTAGLVAFNSLFQVFFYSIFA
YFFVTLLPKWLGLGNFAVHITIGEIATSVFIYLGIPFIAGIISHFGLIKLKGKEWFEEKFIPKISRITLVALLFTIIIMF
AVKGEKVVELPFDVVRIAIPLLLYFVLMFFVSFFLSKKLGTSYPVTASLSFTAGSNNFELAIAVAVGVFGINSGEAFAAV
IGPLVEVPVMIALVNVALKFKKIYFTKESV
>Mature_350_residues
MNQVTKKLSFFDRYLTLWIFVAMGIGVALGYFVPSVATTINDLSVGTTSIPIAIGLILMMYPPLVKVKYGEMGKVFKDWK
VLLLSLVQNWIIGPILMFILAVVFLQGYPSYMIGLIMIGLARCIAMVIVWTDLAHGDSEYTAGLVAFNSLFQVFFYSIFA
YFFVTLLPKWLGLGNFAVHITIGEIATSVFIYLGIPFIAGIISHFGLIKLKGKEWFEEKFIPKISRITLVALLFTIIIMF
AVKGEKVVELPFDVVRIAIPLLLYFVLMFFVSFFLSKKLGTSYPVTASLSFTAGSNNFELAIAVAVGVFGINSGEAFAAV
IGPLVEVPVMIALVNVALKFKKIYFTKESV

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=373, Percent_Identity=33.5120643431635, Blast_Score=169, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 38757; Mature: 38757

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure
MNQVTKKLSFFDRYLTLWIFVAMGIGVALGYFVPSVATTINDLSVGTTSIPIAIGLILMM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
YPPLVKVKYGEMGKVFKDWKVLLLSLVQNWIIGPILMFILAVVFLQGYPSYMIGLIMIGL
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARCIAMVIVWTDLAHGDSEYTAGLVAFNSLFQVFFYSIFAYFFVTLLPKWLGLGNFAVHI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
TIGEIATSVFIYLGIPFIAGIISHFGLIKLKGKEWFEEKFIPKISRITLVALLFTIIIMF
EHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AVKGEKVVELPFDVVRIAIPLLLYFVLMFFVSFFLSKKLGTSYPVTASLSFTAGSNNFEL
HCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEE
AIAVAVGVFGINSGEAFAAVIGPLVEVPVMIALVNVALKFKKIYFTKESV
EEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]